LOCUS       NM_001004699            1755 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 2 subfamily Z member 1
            (OR2Z1), mRNA.
ACCESSION   NM_001004699 XM_210382
VERSION     NM_001004699.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1755)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 1755)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC243312.2.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jan 8, 2021 this sequence version replaced NM_001004699.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641125.1/ ENSP00000493322.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-409               AC243312.2         126789-127197
            410-454             AC243312.2         128261-128305
            455-1755            AC243312.2         136015-137315
FEATURES             Location/Qualifiers
     source          1..1755
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.2"
     gene            1..1755
                     /gene="OR2Z1"
                     /gene_synonym="OR19-4; OR2Z2"
                     /note="olfactory receptor family 2 subfamily Z member 1"
                     /db_xref="GeneID:284383"
                     /db_xref="HGNC:HGNC:15391"
     exon            1..409
                     /gene="OR2Z1"
                     /gene_synonym="OR19-4; OR2Z2"
                     /inference="alignment:Splign:2.1.0"
     exon            410..454
                     /gene="OR2Z1"
                     /gene_synonym="OR19-4; OR2Z2"
                     /inference="alignment:Splign:2.1.0"
     exon            455..1755
                     /gene="OR2Z1"
                     /gene_synonym="OR19-4; OR2Z2"
                     /inference="alignment:Splign:2.1.0"
     CDS             624..1568
                     /gene="OR2Z1"
                     /gene_synonym="OR19-4; OR2Z2"
                     /note="olfactory receptor, family 2, subfamily Z, member
                     2; olfactory receptor OR19-4; olfactory receptor 2Z2"
                     /codon_start=1
                     /product="olfactory receptor 2Z1"
                     /protein_id="NP_001004699.1"
                     /db_xref="CCDS:CCDS32895.1"
                     /db_xref="GeneID:284383"
                     /db_xref="HGNC:HGNC:15391"
                     /translation="MGDVNQSVASDFILVGLFSHSGSRQLLFSLVAVMFVIGLLGNTV
                     LLFLIRVDSRLHTPMYFLLSQLSLFDIGCPMVTIPKMASDFLRGEGATSYGGGAAQIF
                     FLTLMGVAEGVLLVLMSYDRYVAVCQPLQYPVLMRRQVCLLMMGSSWVVGVLNASIQT
                     SITLHFPYCASRIVDHFFCEVPALLKLSCADTCAYEMALSTSGVLILMLPLSLIATSY
                     GHVLQAVLSMRSEEARHKAVTTCSSHITVVGLFYGAAVFMYMVPCAYHSPQQDNVVSL
                     FYSLVTPTLNPLIYSLRNPEVWMALVKVLSRAGLRQMC"
ORIGIN      
        1 tgccaacctg cacgctggat gcatcttacc ttgtctgtta ttgctgctgt gaatccaagc
       61 aggctggacc tctagatagc agaaggtcac ccatgttgac gttcattcca aaccttccat
      121 aaaatgtgct ggaagcagca aggggtgggc acctcacctt ggccatgggg ccgggactag
      181 aacaacccat ctggcatggg ctggaagcac cttcagctca ctttctggag actgtgacca
      241 tcctacaaca gtgatgctct ggaggaattc tcagctcaga attccaggga agatgagttg
      301 agtgttaagt ccaagaaaga gacagtgtcc agaatagaga cagctcagga tctgaaatca
      361 aactgggttc aaatcccagt ctaccctctt cttagctgtg tgactttaga tgcatcaaag
      421 acagtgggac cacctgggca ccctgaaagg aaagcctact gattctagct gcagcctcat
      481 tactcttctc aagacaccat cccaggaagc cactaccaat caatgatgat tggcatgtga
      541 gatgaaaatt atttgccacc ccatgcaggc ttcttgccat agttcagctg ttcttcctgc
      601 agctaaagtg cattgtgtaa aacatggggg atgtgaatca gtcggtggcc tcagacttca
      661 ttctggtggg cctcttcagt cactcaggat cacgccagct cctcttctcc ctggtggctg
      721 tcatgtttgt cataggcctt ctgggcaaca ccgttcttct cttcttgatc cgtgtggact
      781 cccggctcca cacacccatg tacttcctgc tcagccagct ctccctgttt gacattggct
      841 gtcccatggt caccatcccc aagatggcat cagactttct gcggggagaa ggtgccacct
      901 cctatggagg tggtgcagct caaatattct tcctcacact gatgggtgtg gctgagggcg
      961 tcctgttggt cctcatgtct tatgaccgtt atgttgctgt gtgccagccc ctgcagtatc
     1021 ctgtacttat gagacgccag gtatgtctgc tgatgatggg ctcctcctgg gtggtaggtg
     1081 tgctcaacgc ctccatccag acctccatca ccctgcattt tccctactgt gcctcccgta
     1141 ttgtggatca cttcttctgt gaggtgccag ccctactgaa gctctcctgt gcagatacct
     1201 gtgcctacga gatggcgctg tccacctcag gggtgctgat cctaatgctc cctctttccc
     1261 tcatcgccac ctcctacggc cacgtgttgc aggctgttct aagcatgcgc tcagaggagg
     1321 ccagacacaa ggctgtcacc acctgctcct cgcacatcac ggtagtgggg ctcttttatg
     1381 gtgccgccgt gttcatgtac atggtgcctt gcgcctacca cagtccacag caggataacg
     1441 tggtttccct cttctatagc cttgtcaccc ctacactcaa cccccttatc tacagtctga
     1501 ggaatccgga ggtgtggatg gctttggtca aagtgcttag cagagctgga ctcaggcaaa
     1561 tgtgctgact acatagaaac tgctggtgag attccagcgg tcctcgatcc cacccacctt
     1621 cccaaagtat gcatttggca ttcaattgcc aatttgtgca actggccaaa tatccagcca
     1681 ttgcccaagg tgcaactttt tgagaaaatg tctgcctttt aaattgaggt agaatacacg
     1741 taacataaaa tgagc
//
