LOCUS       NM_001258283            2423 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 2 subfamily V member 1
            (OR2V1), mRNA.
ACCESSION   NM_001258283
VERSION     NM_001258283.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2423)
  AUTHORS   Barnes,I.H.A., Ibarra-Soria,X., Fitzgerald,S., Gonzalez,J.M.,
            Davidson,C., Hardy,M.P., Manthravadi,D., Van Gerven,L.,
            Jorissen,M., Zeng,Z., Khan,M., Mombaerts,P., Harrow,J., Logan,D.W.
            and Frankish,A.
  TITLE     Expert curation of the human and mouse olfactory receptor gene
            repertoires identifies conserved coding regions split across two
            exons
  JOURNAL   BMC Genomics 21 (1), 196 (2020)
   PUBMED   32126975
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC008620.12.
            
            On Aug 6, 2020 this sequence version replaced NM_001258283.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA2148874, SAMEA2151887
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641551.1/ ENSP00000492946.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-120               AC008620.12        73297-73416         c
            121-163             AC008620.12        72420-72462         c
            164-219             AC008620.12        71767-71822         c
            220-2423            AC008620.12        65369-67572         c
FEATURES             Location/Qualifiers
     source          1..2423
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q35.3"
     gene            1..2423
                     /gene="OR2V1"
                     /gene_synonym="OR2V1P; OST265"
                     /note="olfactory receptor family 2 subfamily V member 1"
                     /db_xref="GeneID:26693"
                     /db_xref="HGNC:HGNC:8280"
     exon            1..120
                     /gene="OR2V1"
                     /gene_synonym="OR2V1P; OST265"
                     /inference="alignment:Splign:2.1.0"
     exon            121..163
                     /gene="OR2V1"
                     /gene_synonym="OR2V1P; OST265"
                     /inference="alignment:Splign:2.1.0"
     exon            164..219
                     /gene="OR2V1"
                     /gene_synonym="OR2V1P; OST265"
                     /inference="alignment:Splign:2.1.0"
     exon            220..2423
                     /gene="OR2V1"
                     /gene_synonym="OR2V1P; OST265"
                     /inference="alignment:Splign:2.1.0"
     CDS             241..1188
                     /gene="OR2V1"
                     /gene_synonym="OR2V1P; OST265"
                     /note="olfactory receptor, family 2, subfamily V, member 1
                     pseudogene"
                     /codon_start=1
                     /product="olfactory receptor 2V1"
                     /protein_id="NP_001245212.1"
                     /db_xref="CCDS:CCDS58992.1"
                     /db_xref="GeneID:26693"
                     /db_xref="HGNC:HGNC:8280"
                     /translation="MGRWVNQSYTDGFFLLGIFSHSQTDLVLFSAVMVVFTVALCGNV
                     LLIFLIYLDAGLHTPMYFFLSQLSLMDLMLVCNIVPKMAANFLSGRKSISFVGCGIQI
                     GFFVSLVGSEGLLLGLMAYDRYVAVSHPLHYPILMNQRVCLQITGSSWAFGIIDGVIQ
                     MVAAMGLPYCGSRSVDHFFCEVQALLKLACADTSLFDTLLFACCVFMLLLPFSIIMAS
                     YACILGAVLRIRSAQAWKKALATCSSHLTAVTLFYGAAMFMYLRPRRYRAPSHDKVAS
                     IFYTVLTPMLNPLIYSLRNGEVMGALRKGLDRCRIGSQH"
ORIGIN      
        1 agaaccgtgg acttcagccc catccccagc agcccacgaa gacactgacc ctgcagaaac
       61 gcctgtcagg tttatgagga tcccaaccag gcccccaggc tccacccgac tctcgtgaag
      121 gtgactctgc tgagtttgtt cccctgcagg gacccaccca caggatcttg ccgtctgtgt
      181 cctgagaggc acaagtggct ggtgcctctg aacatggtgg tgacagtgaa caactaagcc
      241 atgggaagat gggtgaacca gtcctacaca gatggcttct tcctcttggg catcttttcc
      301 cacagccaga ctgaccttgt cctcttctct gcagttatgg tggtcttcac agtggccctc
      361 tgtgggaatg tcctcctcat cttcctcatc tacctggacg ctggacttca cacccccatg
      421 tacttcttcc tcagccagct ctccctcatg gacctcatgt tggtctgtaa cattgtgcca
      481 aagatggcag ccaacttcct gtctggcagg aagtccatct cctttgtggg ctgtggcata
      541 caaattggct tttttgtctc tcttgtggga tctgaggggc tcttgctggg actcatggct
      601 tatgaccgct acgtggccgt tagccaccca cttcactatc ccatcctcat gaatcagagg
      661 gtctgtctcc agattactgg gagctcctgg gcctttggga taatagatgg agtgattcag
      721 atggtggcag ccatgggctt accttactgt ggctcaagga gcgtggatca ctttttctgt
      781 gaggtacaag ctttattgaa gctggcctgt gcagacactt ccctttttga caccctcctc
      841 tttgcttgct gtgtcttcat gcttctcctt cccttctcca tcatcatggc ctcctatgct
      901 tgcatcctag gggctgtgct ccgaatacgc tctgctcagg cctggaaaaa agccctggcc
      961 acctgctcct cccacctaac agctgtcacc ctcttctatg gggcagccat gttcatgtac
     1021 ctgaggccta ggcgctaccg ggcccctagc catgacaagg tggcctctat cttctacaca
     1081 gtccttactc ccatgctgaa ccccctcatt tacagcttga ggaatgggga ggtgatgggg
     1141 gcactgagga aggggctgga ccgctgcagg attggcagcc agcactgaac cccagagtct
     1201 ggtgcctgct gtgccccttc ttgcctgtgt cacattggga agtcactcaa cctttgtgag
     1261 tgtctgtttc cattcacctg ttgatggtca ttggatggtt tataggtttt ggccatcatg
     1321 agaaaagcca ttatgaacat ttctgtacca aaaaaaaagg aaaaaaagat aatcaggaca
     1381 ctcgtgctct gagggatttt gtaaagatca caatgtgtca atctaaagct ccatgaagaa
     1441 gcaacggctg ctattattgt cattgttgat tgtttatgac atccttggac taaatttact
     1501 ctatttttta ttttctttat tttatttttt gtgtttttct gccctttagt gctatatttc
     1561 ttaattcttc ttggtaatag ctgtctttta ttggatgctt actaagttct aggttcctgt
     1621 tccttttcta ttctttctaa attatttaat tgatgactta gactaacaaa tgtggatatc
     1681 ttaagtggaa actttctaaa tggcagaaat tgagtcccta taactctttt tggacagttc
     1741 tttgcctttt tctatgttca attagaggct ttataaaacc tcctttaagt aataaaaata
     1801 aatccctgca gtttagtagt tatcctcgtg gggggaatat cttgtttttt tgtgtgtgtt
     1861 atgaaaggag gatatcttgg gcccccaaaa tcacgaggat aaagggaaaa gtcaaggtgg
     1921 gaactgctca gggcaaacct gcctcccatt ctttcaaagt cagccctctg ctcactgaga
     1981 tcgatgcagc ttctgattga ctcctttgga atgtctcatc ggaaactcaa aagactgcaa
     2041 ccatttgtct ctcacctacc tgtgacctgg aagccccctc cctgcttcga gctgtccccg
     2101 cctttctgga tggaaccagt gtatttctta catacattga ttgatgtctc atgtctccct
     2161 aaaatgtata aaaccaagcg tgccctgacc accttgggca cgtgtcgtca ggacctccgg
     2221 agggccgcgt cacgggtgca cgtcctcaac cttgacaaaa taaactttct aaattaactg
     2281 atatctgtct caaaggttgg gggttcacag tgtattacca gtaccagacc ctgtgcctta
     2341 taagtagcag ttgctcaata aaacattatt gaatgaatgc aagaagagag catcaagtga
     2401 ggtaatataa atggaagcat ttt
//
