LOCUS       NM_001004696             963 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 2 subfamily T member 4
            (OR2T4), transcript variant 1, coding, mRNA.
ACCESSION   NM_001004696 XM_060315
VERSION     NM_001004696.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 963)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC138089.2.
            
            On Nov 17, 2020 this sequence version replaced NM_001004696.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (1, coding) represents the
            protein-coding allele encoded by the GRCh38 reference genome.
            
            Sequence Note: The genomic coordinates were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000366473.4/ ENSP00000355429.3
            polymorphic pseudogene :: based on alignments, homology
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-963               AC138089.2         24859-25821
FEATURES             Location/Qualifiers
     source          1..963
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q44"
     gene            1..963
                     /gene="OR2T4"
                     /gene_synonym="OR1-60; OR2T4Q"
                     /note="olfactory receptor family 2 subfamily T member 4"
                     /db_xref="GeneID:127074"
                     /db_xref="HGNC:HGNC:15016"
     CDS             1..963
                     /gene="OR2T4"
                     /gene_synonym="OR1-60; OR2T4Q"
                     /note="olfactory receptor OR1-60"
                     /codon_start=1
                     /product="olfactory receptor 2T4"
                     /protein_id="NP_001004696.2"
                     /db_xref="CCDS:CCDS31113.2"
                     /db_xref="GeneID:127074"
                     /db_xref="HGNC:HGNC:15016"
                     /translation="MANITWMANHTGWSDFILLGLFRQSKHPALLCVVIFVVFLMALS
                     GNAVLILLIHCDAHLHTPMYFFISQLSLMDMAYISVTVPKMLLDQVMGVNKISAPECG
                     MQMFFYVTLAGSEFFLLATMAYDRYVAICHPLRYPVLMNHRVCLFLSSGCWFLGSVDG
                     FTFTPITMTFPFRGSREIHHFFCEVPAVLNLSCSDTSLYEIFMYLCCVLMLLIPVVII
                     SSSYLLILLTIHGMNSAEGRKKAFATCSSHLTVVILFYGAAIYTYMLPSSYHTPEKDM
                     MVSVFYTILTPVVNPLIYSLRNKDVMGALKKMLTVEPAFQKAME"
     exon            1..963
                     /gene="OR2T4"
                     /gene_synonym="OR1-60; OR2T4Q"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggccaata tcacctggat ggccaaccac actggatggt cggatttcat cctgttggga
       61 ctcttcagac aatccaaaca tccagcacta ctttgtgtgg tcatttttgt ggttttcctg
      121 atggcgttgt ctggaaatgc tgtcctgatc cttctgatac actgtgacgc ccacctccac
      181 acccccatgt actttttcat cagtcaattg tctctcatgg acatggcgta catttctgtc
      241 actgtgccca agatgctcct ggaccaggtc atgggtgtga ataagatctc agcccctgag
      301 tgtgggatgc agatgttctt ctacgtgaca ctagcaggtt cagaattttt ccttctagcc
      361 accatggcct atgaccgcta cgtggccatc tgccatcctc tccgttaccc tgtcctcatg
      421 aaccataggg tgtgtctctt cctgtcatca ggctgctggt tcctgggctc agtggatggc
      481 ttcacattca ctcccatcac catgaccttc cccttccgtg gatcccggga gattcatcat
      541 ttcttctgtg aagttcctgc tgtattgaat ctctcctgct cagacacctc actctatgag
      601 attttcatgt acttgtgctg tgtcctcatg ctcctcatcc ctgtggtgat catttcaagc
      661 tcctatttac tcatcctcct caccatccac gggatgaact cagcagaggg ccggaaaaag
      721 gcctttgcca cctgctcctc ccacctgact gtggtcatcc tcttctatgg ggctgccatc
      781 tacacctaca tgctccccag ctcctaccac acccctgaga aggacatgat ggtatctgtc
      841 ttctatacca tcctcactcc agtggtgaac cctttaatct atagtcttag gaataaggat
      901 gtcatggggg ctctgaagaa aatgttaaca gtggaacctg cctttcaaaa agctatggag
      961 tag
//
