LOCUS       NM_001004136            3405 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 2 subfamily T member 2
            (OR2T2), mRNA.
ACCESSION   NM_001004136 XM_937468
VERSION     NM_001004136.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3405)
  AUTHORS   Barnes,I.H.A., Ibarra-Soria,X., Fitzgerald,S., Gonzalez,J.M.,
            Davidson,C., Hardy,M.P., Manthravadi,D., Van Gerven,L.,
            Jorissen,M., Zeng,Z., Khan,M., Mombaerts,P., Harrow,J., Logan,D.W.
            and Frankish,A.
  TITLE     Expert curation of the human and mouse olfactory receptor gene
            repertoires identifies conserved coding regions split across two
            exons
  JOURNAL   BMC Genomics 21 (1), 196 (2020)
   PUBMED   32126975
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3405)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   3  (bases 1 to 3405)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC138089.2.
            
            On Aug 4, 2020 this sequence version replaced NM_001004136.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000641925.2/
                                                ENSP00000492947.1
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                AC138089.2         108830-108862
            34-256              AC138089.2         109782-110004
            257-455             AC138089.2         112387-112585
            456-3405            AC138089.2         115969-118918
FEATURES             Location/Qualifiers
     source          1..3405
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q44"
     gene            1..3405
                     /gene="OR2T2"
                     /gene_synonym="OR1-43; OR2T2P"
                     /note="olfactory receptor family 2 subfamily T member 2"
                     /db_xref="GeneID:401992"
                     /db_xref="HGNC:HGNC:14725"
     exon            1..33
                     /gene="OR2T2"
                     /gene_synonym="OR1-43; OR2T2P"
                     /inference="alignment:Splign:2.1.0"
     exon            34..256
                     /gene="OR2T2"
                     /gene_synonym="OR1-43; OR2T2P"
                     /inference="alignment:Splign:2.1.0"
     exon            257..455
                     /gene="OR2T2"
                     /gene_synonym="OR1-43; OR2T2P"
                     /inference="alignment:Splign:2.1.0"
     exon            456..3405
                     /gene="OR2T2"
                     /gene_synonym="OR1-43; OR2T2P"
                     /inference="alignment:Splign:2.1.0"
     CDS             478..1452
                     /gene="OR2T2"
                     /gene_synonym="OR1-43; OR2T2P"
                     /note="olfactory receptor, family 2, subfamily T, member 2
                     pseudogene; olfactory receptor OR1-43"
                     /codon_start=1
                     /product="olfactory receptor 2T2"
                     /protein_id="NP_001004136.1"
                     /db_xref="CCDS:CCDS31116.1"
                     /db_xref="GeneID:401992"
                     /db_xref="HGNC:HGNC:14725"
                     /translation="MGMEGLLQNSTNFVLTGLITHPAFPGLLFAIVFSIFVVAITANL
                     VMILLIHMDSRLHTPMYFLLSQLSIMDTIYICITVPKMLQDLLSKDKTISFLGCAVQI
                     FLYLTLIGGEFFLLGLMAYDRYVAVCNPLRYPLLMNRRVCLFMVVGSWVGGSLDGFML
                     TPVTMSFPFCRSREINHFFCEIPAVLKLSCTDTSLYETLMYACCVLMLLIPLSVISVS
                     YTHILLTVHRMNSAEGRRKAFATCSSHIMVVSVFYGAAFYTNVLPHSYHTPEKDKVVS
                     AFYTILTPMLNPLIYSLRNKDVAAALRKVLGRCGSSQSIRVATVIRKG"
ORIGIN      
        1 gctttagaaa gacttggacc cagcttctct gagcgttagc agggtggact ggatgggcca
       61 tatgccagat cctttgattt ctatttgcca ccacacgaac tgacactgct gcccagaagc
      121 attcccctgc acatccacat cacagccctc ctgctggcag cttggaattt agacctttta
      181 ctctcaatgc tccaggaaac cagatgtact tctttctttc ttgtccattg gtgatatcct
      241 tgacaatgta gtttagcttt acaggtacgt tgtgtcaagt ggagaagatc agttctggtt
      301 agcagcttta ttgccacaga aaggacactg gcagatactt ctcatagctc tagtcatgct
      361 gaattcccgg aaaggggtgt cagaatgaat tgctctaagc tcttctccct ggtagaagaa
      421 cctgtgactt ctcttggaga tctcttcaat tttcgcccaa ggagcttgtc atggaccatg
      481 ggcatggagg gtcttctcca gaactccact aacttcgtcc tcacaggcct catcacccat
      541 cctgccttcc ccgggcttct ctttgcaata gtcttctcca tctttgtggt ggctataaca
      601 gccaacttgg tcatgattct gctcatccac atggactccc gcctccacac acccatgtac
      661 ttcttgctca gccagctctc catcatggat accatctaca tctgtatcac tgtccccaag
      721 atgctccagg acctcctgtc caaggacaag accatttcct tcctgggctg tgcagttcag
      781 atcttcctct acctgaccct gattggaggg gaattcttcc tgctgggtct catggcctat
      841 gaccgctatg tggctgtgtg caaccctcta cggtaccctc tcctcatgaa ccgcagggtt
      901 tgcttattca tggtggtcgg ctcctgggtt ggtggttcct tggatgggtt catgctgact
      961 cctgtcacta tgagtttccc cttctgtaga tcccgagaga tcaatcactt tttctgtgag
     1021 atcccagccg tgctgaagtt gtcttgcaca gacacgtcac tctatgagac cctgatgtat
     1081 gcctgctgcg tgctgatgct gcttatccct ctatctgtca tctctgtctc ctacacgcac
     1141 atcctcctga ctgtccacag gatgaactct gctgagggcc ggcgcaaagc ctttgctacg
     1201 tgttcctccc acattatggt ggtgagcgtt ttctacgggg cagccttcta caccaacgtg
     1261 ctgccccact cctaccacac tccagagaaa gataaagtgg tgtctgcctt ctacaccatc
     1321 ctcaccccca tgctcaaccc actcatctac agcttgagga ataaagatgt ggctgcagct
     1381 ctgaggaaag tactagggag atgtggttcc tcccagagca tcagggtggc gactgtgatc
     1441 aggaagggct agcagggact cccacagcat cagagtggtg actgtgatcg ggaaggatta
     1501 gcggggactc ccagagcatc aggggtggtg actgatcagg aaggactagc aaggactagc
     1561 gcaaacatct gcggtgctgc ggccaataac gcagctatta cagaaaatat ggtattggtt
     1621 ctgaagaatg ttcagtgtca ctttcagcaa ttcaaaatta acaggcaaaa tcatcctgtt
     1681 gcaaggatta cttaggaaca gtagcgaagt tggtgagcat ctccgcatta gtcaactttg
     1741 ttcaactgga ttcacaaaca tttccagagg gcattctcag tcaagtagcc ctacaaacca
     1801 ttcatggcac gccaagcagc tcttggaagt gcccatgtta acatgtgacc atgagtcctt
     1861 cctgtctgta ttgctaacgt gtgatcatga gtcctgcctg cctgtattgc tgacgtgtga
     1921 tcatgagtcc tgcctgtctg tattgctaac gtgtgatgag tccttctgtg tctgtattgc
     1981 taacgtgtga tcgtgagtcc ttcctgtcta tattgctaat gtgtgaccat gagtcctgcc
     2041 tgtctgtatt gctaacgtgt gaccatgagt cctgcctgtc tgtattgcta acgtgtgatc
     2101 atgggtcctg cctgtctgta ttgctaacgt gtgatcatgg gtcctgcctg tctgtattgc
     2161 taacacgtga ttgagtcctg cctgtctcta ttgttaacct gtgatcatga gtcctgcctg
     2221 tctgtctgta ttgctgacca acttttgaat ggaaattgga aggagcattt gccacctcct
     2281 tgatgactta atttcaaaca ttcaatacaa gtaaaatatt ttctagtgct aaatgtgtag
     2341 caattttatt agaaaacatt taggaaggtg atactatttt tggttccatg ttcttagtta
     2401 cattttatga atgttatcac ttacctctga aattaaatac ttgccctgcc tttattcaca
     2461 tggagtccaa tatattcctg gaaatattga ttcattgatt gaaaattgac tctgccatta
     2521 agattgttac atggccaaaa acctacaaaa ctgccattta tgctcaaatt gttaatagat
     2581 aaatgtagaa tgaataaacc aagacatttt attagctaac ttagttcccg tggaataagt
     2641 tgctcaattt tcttattctc aacatcttca ttgatatgct gaagacaagt atttttgtaa
     2701 ttagttggag ttaggtgtgg tgctttgata gatgtgtaac tttggtggaa tactaactaa
     2761 gcaaagacta cactgacccc accattcatg taactttagt ttctcctgtg tgtaaggtcc
     2821 tgaaatatga gacataaaaa atattgacgg acctggtgtt tattttcttt gttgatacga
     2881 ggcttagaaa acattggaca gagcggttac atagttgaca aagactaagc aaaggttact
     2941 cagccttatg ttgttctagt gtcaacacag atagaaggaa aaatgtttcc tccattgttg
     3001 ctgacgtaga taaagaatat tcccttcaat atgctaaccc ctaggtggct tttcattcag
     3061 aaggttccta ataatttgat ctttaccctg aaatcaaaca catggaaaag agatggaaga
     3121 atgtcctgga gggattaagt gaagaaacag accaggattc atttatgaaa tatcctcggt
     3181 gttatttcaa ttcagctcca ttcacatttt attcttttgt gtctctgcac taatgccctc
     3241 catattctcc attctcctgc cttagctagc accttctcga tcttccctct acaaaactcc
     3301 ttcagttcac attgcatttg tgctctatcc tgggatatgt gttttctttc ccatttcctc
     3361 agttgctatg tattaaaaat taggactttt attcttatgt ttcca
//
