LOCUS       NM_001258284            2429 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 2 subfamily L member 5
            (OR2L5), mRNA.
ACCESSION   NM_001258284
VERSION     NM_001258284.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2429)
  AUTHORS   Barnes,I.H.A., Ibarra-Soria,X., Fitzgerald,S., Gonzalez,J.M.,
            Davidson,C., Hardy,M.P., Manthravadi,D., Van Gerven,L.,
            Jorissen,M., Zeng,Z., Khan,M., Mombaerts,P., Harrow,J., Logan,D.W.
            and Frankish,A.
  TITLE     Expert curation of the human and mouse olfactory receptor gene
            repertoires identifies conserved coding regions split across two
            exons
  JOURNAL   BMC Genomics 21 (1), 196 (2020)
   PUBMED   32126975
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2429)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC099570.2.
            
            On Aug 5, 2020 this sequence version replaced NM_001258284.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000355281.2/ ENSP00000347428.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                AC099570.2         148355-148433
            80-2429             AC099570.2         156622-158971
FEATURES             Location/Qualifiers
     source          1..2429
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q44"
     gene            1..2429
                     /gene="OR2L5"
                     /gene_synonym="OR2L11; OR2L5P"
                     /note="olfactory receptor family 2 subfamily L member 5"
                     /db_xref="GeneID:81466"
                     /db_xref="HGNC:HGNC:15011"
     exon            1..79
                     /gene="OR2L5"
                     /gene_synonym="OR2L11; OR2L5P"
                     /inference="alignment:Splign:2.1.0"
     exon            80..2429
                     /gene="OR2L5"
                     /gene_synonym="OR2L11; OR2L5P"
                     /inference="alignment:Splign:2.1.0"
     CDS             101..1039
                     /gene="OR2L5"
                     /gene_synonym="OR2L11; OR2L5P"
                     /note="olfactory receptor, family 2, subfamily L, member
                     11; olfactory receptor, family 2, subfamily L, member 5
                     pseudogene; seven transmembrane helix receptor; olfactory
                     receptor OR1-53; olfactory receptor 2L11"
                     /codon_start=1
                     /product="olfactory receptor 2L5"
                     /protein_id="NP_001245213.1"
                     /db_xref="CCDS:CCDS58068.1"
                     /db_xref="GeneID:81466"
                     /db_xref="HGNC:HGNC:15011"
                     /translation="MENYNQTSTDFILLGLFPPSKIGLFLFILFVLIFLMALIGNLSM
                     ILLIFLDTHLHTPMYFLLSQLSLIDLNYISTIVPKMASDFLYGNKSISFIGCGIQSFF
                     FMTFAGAEALLLTSMAYDRYVAICFPLHYPIRMSKRMYVLMITGSWMIGSINSCAHTV
                     YAFRIPYCKSRAINHFFCDVPAMLTLACTDTWVYEYTVFLSSTIFLVFPFTGIACSYG
                     WVLLAVYRMHSAEGRKKAYSTCSTHLTVVTFYYAPFAYTYLCPRSLRSLTEDKVLAVF
                     YTILTPMLNPIIYSLRNKEVMGALTRVIQNIFSVKM"
ORIGIN      
        1 ctttgttcat atgatgacta tacgactgct ggcagccaac aaaggcagtg cgtgtttgaa
       61 attgaggaga taataaaagg aaggatcgta tgaatgcccc atggaaaatt acaatcaaac
      121 gtcaactgat ttcatcttat tggggctgtt cccaccatca aaaattggcc ttttcctctt
      181 cattctcttt gttctcattt tcctaatggc tctaattgga aacctatcca tgattcttct
      241 catcttcttg gacacccatc tccacacacc catgtatttc ctgcttagtc agctctccct
      301 cattgaccta aattacatct ctacgattgt tcctaagatg gcttctgatt ttctgtatgg
      361 aaacaagtct atctccttca ttgggtgtgg gattcagagt ttcttcttca tgacttttgc
      421 aggtgcagaa gcgctgctcc tgacatcaat ggcctatgat cgttatgtgg ccatttgctt
      481 tcctctccac tatcccatcc gtatgagcaa aagaatgtat gtgctgatga taacaggatc
      541 ttggatgata ggctccatca actcttgtgc tcacacagta tatgcattcc gtatcccata
      601 ttgcaagtcc agagccatca atcatttttt ctgtgatgtt ccagctatgt tgacattagc
      661 ctgtacagac acctgggtct atgagtacac agtgtttttg agcagcacca tctttcttgt
      721 gtttcccttc actggcattg cgtgttccta tggctgggtt ctccttgctg tctaccgcat
      781 gcactctgca gaagggagga aaaaggccta ttcgacctgc agcacccacc tcactgtagt
      841 aactttctac tatgcaccct ttgcttatac ctatctatgt ccaagatccc tgcgatctct
      901 gacagaggac aaggttctgg ctgttttcta caccatcctc accccaatgc tcaaccccat
      961 catctacagc ctgagaaaca aggaggtgat gggggccctg acacgagtga ttcagaatat
     1021 cttctcggtg aaaatgtaga catacgttct gtgttagagt caaagcgcta ggttcatatc
     1081 aactcagcag tgtacagcag tgaagaaaaa cattattaca tgcccagtat gtcaaacaga
     1141 gattaatcca gaatgtttgt cttttaattt agtcttgaca ttatagttgc atattctaag
     1201 acatctattt tgtttctgtt tgtgtttctt tttatcaaaa gacagatcat atattttaca
     1261 ctaaattgta aggccataga atttcattat catgtataaa tcaaaacaat aaatgtccaa
     1321 aggaatcata tcattcagca taatagttat atgttaattg tttcccatta ttattaaaat
     1381 aagacaaaat aacaaattat ttaagattac tgaatctaat tgaatattaa ataatatttt
     1441 atttactctc aactggtgtg tatgtgttcc tctttttgct aaagtaatga tttattaata
     1501 aatttacctc aggataaata agtatgtctg gggtgaagcc aatttgcctt tagtaaaaca
     1561 acaatttctt tataaaagat tctatggaat ttaccttcta tagaacctct tagactacag
     1621 ttgacttaga cttagttgaa tgtggagtag gttatttgaa ccattcccca gtcacatcac
     1681 aacacacaca atgtttgtct cctgagtagc cacgggtatt ctcatgcaag acgttctctt
     1741 ctgaacaatt tttttctact tactcttcaa aatcagcaag tctatacatc ttggattggg
     1801 atcaactcct ctgctccact atttttatac ctgcttaggc ctgtgcctag aaggatcaac
     1861 attattttta taaaagttgt cagcttaggt ccattctctg agtgaaaggc catggctctc
     1921 cacaagagcc cattcctgag aaacgcttta gtctctgagg agaggaggca agaaggaagg
     1981 tagaatgaac aagtaagaga aaagccctgc attatacaac tttccataat gtaacatttt
     2041 tctataacta tttttctaaa gttctttctg ttgctctcaa atagaataat cttcactctg
     2101 gaaatataat taaagtgcat aaaaactatt tatctgaaga ataacatcat gtgatcagaa
     2161 aatatatttt tatttttatt tgttattaat tttatttgtt tattttgttt attttttatg
     2221 ggggttctgg catatgtgag cagaacgtgc aggtttgtta cacaggtata catgtgccgt
     2281 tgtggtttgc tgcaccaata aacccgtcat ctaagtttta agccccatat gctttaggta
     2341 tttgtcctaa tgctctccct ccccttgccc aagaatttgt aatgatagcc attaaaatcc
     2401 caatgtagaa aattttatat ctgatttga
//
