LOCUS       NM_001348294            2311 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 2 subfamily J member 1
            (OR2J1), mRNA.
ACCESSION   NM_001348294
VERSION     NM_001348294.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2311)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL662791.3 and AL645937.6.
            
            On Jul 21, 2020 this sequence version replaced NM_001348294.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. This olfactory receptor gene is a
            segregating pseudogene, where some individuals have an allele that
            encodes a functional olfactory receptor, while other individuals
            have an allele encoding a protein that is predicted to be
            non-functional. [provided by RefSeq, Jan 2017].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments. This gene is a segregating
            pseudogene. This RefSeq represents the protein encoded by the
            reference genome allele.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641659.2/ ENSP00000493312.1
            polymorphic pseudogene :: based on alignments, homology
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-242               AL662791.3         134222-134463
            243-369             AL645937.6         2000-2126
            370-2311            AL645937.6         3028-4969
FEATURES             Location/Qualifiers
     source          1..2311
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p22.1"
     gene            1..2311
                     /gene="OR2J1"
                     /gene_synonym="6M1-4P; dJ80I19.2; hs6M1-4; OR2J1P; OR6-15;
                     OR6-5"
                     /note="olfactory receptor family 2 subfamily J member 1"
                     /db_xref="GeneID:442185"
                     /db_xref="HGNC:HGNC:8259"
     exon            1..369
                     /gene="OR2J1"
                     /gene_synonym="6M1-4P; dJ80I19.2; hs6M1-4; OR2J1P; OR6-15;
                     OR6-5"
                     /inference="alignment:Splign:2.1.0"
     exon            370..2311
                     /gene="OR2J1"
                     /gene_synonym="6M1-4P; dJ80I19.2; hs6M1-4; OR2J1P; OR6-15;
                     OR6-5"
                     /inference="alignment:Splign:2.1.0"
     CDS             553..1491
                     /gene="OR2J1"
                     /gene_synonym="6M1-4P; dJ80I19.2; hs6M1-4; OR2J1P; OR6-15;
                     OR6-5"
                     /note="olfactory receptor, family 2, subfamily J, member 1
                     pseudogene; olfactory receptor OR6-15; olfactory receptor
                     6-5"
                     /codon_start=1
                     /product="olfactory receptor 2J1"
                     /protein_id="NP_001335223.1"
                     /db_xref="CCDS:CCDS87377.1"
                     /db_xref="GeneID:442185"
                     /db_xref="HGNC:HGNC:8259"
                     /translation="MLMKKNASFEDFFLLLGFSNWPHLEVVLFVVILIFYLITLIGNL
                     FIIILSYLDSHLHTPMYFFLSNLSFLDLCYTTSSIPQLLVNLWGPEKTISYAGCTVQL
                     YFVLALGTAECVLLVVMSYDRYAAVCRPLHYTVLMHPRFCRLLAAASWVSGFTTSALH
                     SSFTFWIPLCRHRLVDHFFCEVPALLRLSCVDTQANELTLMVMSSIFVLIPLILILTS
                     YGAIARAVLSMQSTTGLQKVLRTCGAHLMVVSLFFIPVMCMYLQPPSENSQDQGKFIA
                     LFYTVVTPSLNPLIYTFRNKDVRGAVKRLMGWEWGM"
ORIGIN      
        1 aattactgta gtaaggaagt caggcagctg cattaggaaa gaaaattata cctgcattag
       61 caaaagtatc cacaacattt gagttcaagt atcttacaga atattacctt tcaacctagc
      121 gaaattttta aaaaaattct tgcaattttt ccatgatttc tcaaaaggta atgatcattt
      181 cattatcaac aatatggaaa agtgtacaga tatctttgta cctgtctgga gcatctgcac
      241 agacttggcc caagttcaac gttcctagct ctccagctgt aactcaacta attaggcaaa
      301 cccttacatc tttttcaaga gtcaagatta gaatatttga gttgttaaaa gtttttcaaa
      361 acactgaagc tggacaaata tctcaatgaa gcatacaaag gaaactgtat aaaaattcta
      421 ctgccataat ggtgcacact atctggaatt gggatacttt tttctccaat ctgtttgcaa
      481 gtgagcagtt ggcaatgcat ggacagactt tgagtttatg cgattctttc tttaggtaca
      541 ggaaaaataa gaatgttgat gaaaaaaaat gcaagttttg aagacttctt tcttctactt
      601 ggattttcta actggcctca tctggaagta gttctctttg tggttatctt gatcttctac
      661 ttgataacac tgataggaaa cctgttcatc atcatcctgt catacctgga ctcccatctc
      721 cacactccca tgtacttctt cctttcaaat ctctcatttc tggatctctg ctacaccacc
      781 agctctatcc ctcagttgct ggtgaatctc tggggcccgg aaaagaccat ctcttatgct
      841 ggttgtacgg ttcaacttta ctttgttctc gcactgggaa ccgcagagtg tgtcctactg
      901 gtggtgatgt cctatgatcg ttatgcagct gtgtgtagac ctttgcatta cactgtcctc
      961 atgcaccctc gtttctgccg cttgttggct gcggcttctt gggtaagtgg ttttacaacc
     1021 tcagcacttc attcctcctt tactttctgg atacccctat gtagacatcg cctagtggat
     1081 cacttcttct gtgaagttcc agcacttctg cgattatcat gtgttgatac ccaggcaaat
     1141 gagctgaccc tcatggtcat gagctccata tttgttctca tacctctcat cctcatcctc
     1201 acttcctatg gtgccattgc ccgggctgta ctgagcatgc aatcaaccac tgggcttcag
     1261 aaagtgctta ggacatgtgg agcccatctt atggttgtat ctctcttttt cattccagtc
     1321 atgtgcatgt atctccagcc accatcagaa aattctcaag atcaaggcaa gttcattgcc
     1381 ctcttttaca ctgttgtcac acctagtctt aaccctctaa tctacacttt cagaaacaag
     1441 gatgtaagag gggcagtgaa gagactaatg gggtgggaat gggggatgtg acagggaaat
     1501 catgttggct gttgtttttc ctagggtctt atccattttg aaaggttgtt tccctgcttc
     1561 tttgtgattt gtgtttcatc taacagctca caaaacatgg aatagttcag ttcccccatt
     1621 tgttgctctg tttaatattt agttctgaaa tattatgttg agataaaggt tttgattagt
     1681 accattttgt tcttttacaa ttctatattt atttccatga aaattgtgga ctgtggtttc
     1741 aacataaata aatgtgtgtg tgaataatta tgaggagatt atttaaaaaa tattggcaat
     1801 atttctgaca atgtgctaaa ttatgaactg accattgata tgtataggaa gagaagggca
     1861 atattgcaaa gatgtaggct gaagaagttt ttggttatta aataaacctt aaatgaagct
     1921 aaaaatagtc acagcaaaga aaaatagtaa acataatgaa taacaccatt tattatatgg
     1981 taaaggatat gtcataattt tttggttgaa gttcactttt taaagacact aaattatata
     2041 atttatcctg taggtctgca ttcttgtcac attgaacagt aaactaatat ctctttaaaa
     2101 tggctgattc gttcatctgt ccatttattc attaacttat tcttcattag ctaaatctta
     2161 ctggacatgt actctctccc agtttgtgaa attcttggta acatgtataa atataacata
     2221 ctttgtctga acagaatgca ctctctatcg ggaaaaatgg caacataaga taaaagatga
     2281 agtatctgta catggcttaa tttgtcactg g
//
