LOCUS       NM_012368               1418 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 2 subfamily C member 1
            (OR2C1), mRNA.
ACCESSION   NM_012368
VERSION     NM_012368.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1418)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 1418)
  AUTHORS   Centola,M., Chen,X., Sood,R., Deng,Z., Aksentijevich,I., Blake,T.,
            Ricke,D.O., Chen,X., Wood,G., Zaks,N., Richards,N., Krizman,D.,
            Mansfield,E., Apostolou,S., Liu,J., Shafran,N., Vedula,A.,
            Hamon,M., Cercek,A., Kahan,T., Gumucio,D., Callen,D.F.,
            Richards,R.I., Moyzis,R.K., Doggett,N.A., Collins,F.S., Liu,P.P.,
            Fischel-Ghodsian,N. and Kastner,D.L.
  TITLE     Construction of an approximately 700-kb transcript map around the
            familial Mediterranean fever locus on human chromosome 16p13.3
  JOURNAL   Genome Res 8 (11), 1172-1191 (1998)
   PUBMED   9847080
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC126269.1, BC069158.1 and AC025283.6.
            
            On May 17, 2019 this sequence version replaced NM_012368.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC130328.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000304936.4/ ENSP00000307726.2
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-105               BC126269.1         1-105
            106-338             BC069158.1         54-286
            339-498             BC126269.1         339-498
            499-981             BC069158.1         447-929
            982-1036            BC126269.1         982-1036
            1037-1418           AC025283.6         54494-54875
FEATURES             Location/Qualifiers
     source          1..1418
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p13.3"
     gene            1..1418
                     /gene="OR2C1"
                     /gene_synonym="OLFmf3; OR2C2P"
                     /note="olfactory receptor family 2 subfamily C member 1"
                     /db_xref="GeneID:4993"
                     /db_xref="HGNC:HGNC:8242"
     exon            1..1418
                     /gene="OR2C1"
                     /gene_synonym="OLFmf3; OR2C2P"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..991
                     /gene="OR2C1"
                     /gene_synonym="OLFmf3; OR2C2P"
                     /note="olfactory receptor, family 2, subfamily C, member 2
                     pseudogene; olfactory receptor OR16-1; olfactory receptor
                     OR16-2; olfactory receptor 2C2"
                     /codon_start=1
                     /product="olfactory receptor 2C1"
                     /protein_id="NP_036500.2"
                     /db_xref="CCDS:CCDS10502.1"
                     /db_xref="GeneID:4993"
                     /db_xref="HGNC:HGNC:8242"
                     /translation="MDGVNDSSLQGFVLMGISDHPQLEMIFFIAILFSYLLTLLGNST
                     IILLSRLEARLHTPMYFFLSNLSSLDLAFATSSVPQMLINLWGPGKTISYGGCITQLY
                     VFLWLGATECILLVVMAFDRYVAVCRPLRYTAIMNPQLCWLLAVIACLGGLGNSVIQS
                     TFTLQLPLCGHRRVEGFLCEVPAMIKLACGDTSLNQAVLNGVCTFFTAVPLSIIVISY
                     CLIAQAVLKIRSAEGRRKAFNTCLSHLLVVFLFYGSASYGYLLPAKNSKQDQGKFISL
                     FYSLVTPMVNPLIYTLRNMEVKGALRRLLGKGREVG"
ORIGIN      
        1 ttccagcagc ttgcgctaaa tgaattcatc aagtgactga agacaaccag tgatggacgg
       61 ggtgaatgat agctccttgc agggctttgt tctgatgggc atatcagacc atccccagct
      121 ggagatgatc ttttttatag ccatcctctt ctcctatttg ctgaccctac ttgggaactc
      181 aaccatcatc ttgctttccc gcctggaggc ccggctccat acacccatgt acttcttcct
      241 cagcaacctc tcctccttgg accttgcttt cgctactagt tcagtccccc aaatgctgat
      301 caatttatgg ggaccaggca agaccatcag ctatggtggc tgcataaccc agctctatgt
      361 cttcctttgg ctgggggcca ccgagtgcat cctgctggtg gtgatggcat ttgaccgcta
      421 cgtggcagtg tgccggcccc tccgctacac cgccatcatg aacccccagc tctgctggct
      481 gctggctgtg attgcctgcc tgggtggctt gggcaactct gtgatccagt caacattcac
      541 tctgcagctc ccattgtgtg ggcaccggag ggtggaggga ttcctctgcg aggtgcctgc
      601 catgatcaaa ctggcctgtg gcgacacaag tctcaaccag gctgtgctca atggtgtctg
      661 caccttcttc actgcagtcc cactaagcat catcgtgatc tcctactgcc tcattgctca
      721 ggcagtgctg aaaatccgct ctgcagaggg gaggcgaaag gcgttcaata cgtgcctctc
      781 ccatctgctg gtggtgttcc tcttctatgg ctcagccagc tatgggtatc tgcttccggc
      841 caagaacagc aaacaggacc agggcaagtt catttccctg ttctactcgt tggtcacacc
      901 catggtgaat cccctcatct acacgctgcg gaacatggaa gtgaagggcg cactgaggag
      961 gttgctgggg aaaggaagag aagttggctg agagaacact ccttcgttat ttattgcgtc
     1021 ttcatctcta catgcgtttc tcattaactc tctctggcca ggtgaacatg aggaatacta
     1081 attccggtaa aaccaaggca tgttcctgac agccctaagc tgacagccct aagctgttgg
     1141 gaacatggtt agtgttattc gtaatgttct acacttattt accaaaaatc ctactgtgga
     1201 ctaccgatag caggggagac atgttgttga gggctcagag gttattgacc tgtgacagac
     1261 ctgtctcact gtctctgtct ctgttgccca catgttattt aatatgcctt atatttctgc
     1321 agaattctgt acttttctaa gcaaagcacc tccacttgca gtatcttaca taatgttact
     1381 ataattccat aaaatcaagc catgtattat taacttca
//
