LOCUS       NM_012367                942 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 2 subfamily B member 6
            (OR2B6), mRNA.
ACCESSION   NM_012367
VERSION     NM_012367.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 942)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 942)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
REFERENCE   3  (bases 1 to 942)
  AUTHORS   Rouquier,S., Taviaux,S., Trask,B.J., Brand-Arpon,V., van den
            Engh,G., Demaille,J. and Giorgi,D.
  TITLE     Distribution of olfactory receptor genes in the human genome
  JOURNAL   Nat Genet 18 (3), 243-250 (1998)
   PUBMED   9500546
  REMARK    Erratum:[Nat Genet 1998 May;19(1):102]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL133267.9.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC109251.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000244623.1/ ENSP00000244623.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-942               AL133267.9         20708-21649
FEATURES             Location/Qualifiers
     source          1..942
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p22.1"
     gene            1..942
                     /gene="OR2B6"
                     /gene_synonym="dJ408B20.2; OR2B1; OR2B1P; OR2B5; OR2B6P;
                     OR5-40; OR5-41; OR6-31"
                     /note="olfactory receptor family 2 subfamily B member 6"
                     /db_xref="GeneID:26212"
                     /db_xref="HGNC:HGNC:8241"
     CDS             1..942
                     /gene="OR2B6"
                     /gene_synonym="dJ408B20.2; OR2B1; OR2B1P; OR2B5; OR2B6P;
                     OR5-40; OR5-41; OR6-31"
                     /note="olfactory receptor, family 2, subfamily B, member 6
                     pseudogene; olfactory receptor, family 2, subfamily B,
                     member 5; olfactory receptor, family 2, subfamily B,
                     member 1 pseudogene; olfactory receptor OR6-4; hs6M1-32;
                     olfactory receptor 2B1; olfactory receptor 2B5; olfactory
                     receptor 5-40; olfactory receptor 6-31"
                     /codon_start=1
                     /product="olfactory receptor 2B6"
                     /protein_id="NP_036499.1"
                     /db_xref="CCDS:CCDS4642.1"
                     /db_xref="GeneID:26212"
                     /db_xref="HGNC:HGNC:8241"
                     /translation="MNWVNDSIIQEFILLGFSDRPWLEFPLLVVFLISYTVTIFGNLT
                     IILVSRLDTKLHTPMYFFLTNLSLLDLCYTTCTVPQMLVNLCSIRKVISYRGCVAQLF
                     IFLALGATEYLLLAVMSFDRFVAICRPLHYSVIMHQRLCLQLAAASWVTGFSNSVWLS
                     TLTLQLPLCDPYVIDHFLCEVPALLKLSCVETTANEAELFLVSELFHLIPLTLILISY
                     AFIVRAVLRIQSAEGRQKAFGTCGSHLIVVSLFYSTAVSVYLQPPSPSSKDQGKMVSL
                     FYGIIAPMLNPLIYTLRNKEVKEGFKRLVARVFLIKK"
     exon            1..942
                     /gene="OR2B6"
                     /gene_synonym="dJ408B20.2; OR2B1; OR2B1P; OR2B5; OR2B6P;
                     OR5-40; OR5-41; OR6-31"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgaattggg taaatgacag catcatacag gagtttattc tgctgggttt ctcagatcga
       61 ccttggctgg agtttccact ccttgtggtc ttcttgattt cttacactgt gaccatcttt
      121 ggcaatctga ccattattct agtgtcacgc ctggacacca aacttcatac ccccatgtat
      181 ttttttctta ccaatctatc actcctggat ctttgttaca ccacatgtac agtcccacaa
      241 atgctagtaa atttatgcag catcaggaaa gtaatcagtt atcgtggctg tgtagcccag
      301 cttttcatat ttctggcctt gggggctact gaatatcttc tcctggccgt catgtccttt
      361 gataggtttg tagctatttg tcggcctctc cattactcag ttatcatgca ccagagactc
      421 tgcctccagt tggcagctgc atcctgggtt actggtttta gtaactcagt gtggttgtct
      481 accctgactc tccagctgcc actctgtgac ccctatgtga tagatcactt tctctgtgaa
      541 gtccctgcac tgctcaagtt atcttgtgtt gagacaacag caaatgaggc tgaactattc
      601 cttgtcagtg agctcttcca tctaataccc ctgacactca tccttatatc atatgctttt
      661 attgtccgag cagtattgag gatacagtct gctgaaggtc gacaaaaagc atttgggaca
      721 tgtggttccc atctaattgt ggtgtctctt ttttatagta cagccgtctc tgtgtacctg
      781 caaccacctt cgcccagctc caaggaccaa ggaaagatgg tttctctctt ctatggaatc
      841 attgcaccca tgctgaatcc ccttatatat acacttagga acaaggaggt aaaggaaggc
      901 tttaaaaggt tggttgcaag agtcttctta atcaagaaat aa
//
