LOCUS       NM_001005226            1106 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 2 subfamily B member 3
            (OR2B3), mRNA.
ACCESSION   NM_001005226 XM_498068
VERSION     NM_001005226.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1106)
  AUTHORS   St Pourcain,B., Whitehouse,A.J., Ang,W.Q., Warrington,N.M.,
            Glessner,J.T., Wang,K., Timpson,N.J., Evans,D.M., Kemp,J.P.,
            Ring,S.M., McArdle,W.L., Golding,J., Hakonarson,H., Pennell,C.E.
            and Smith,G.D.
  TITLE     Common variation contributes to the genetic architecture of social
            communication traits
  JOURNAL   Mol Autism 4 (1), 34 (2013)
   PUBMED   24047820
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1106)
  AUTHORS   Barcellos,L.F., May,S.L., Ramsay,P.P., Quach,H.L., Lane,J.A.,
            Nititham,J., Noble,J.A., Taylor,K.E., Quach,D.L., Chung,S.A.,
            Kelly,J.A., Moser,K.L., Behrens,T.W., Seldin,M.F., Thomson,G.,
            Harley,J.B., Gaffney,P.M. and Criswell,L.A.
  TITLE     High-density SNP screening of the major histocompatibility complex
            in systemic lupus erythematosus demonstrates strong evidence for
            independent susceptibility regions
  JOURNAL   PLoS Genet 5 (10), e1000696 (2009)
   PUBMED   19851445
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   3  (bases 1 to 1106)
  AUTHORS   Clamp,M., Fry,B., Kamal,M., Xie,X., Cuff,J., Lin,M.F., Kellis,M.,
            Lindblad-Toh,K. and Lander,E.S.
  TITLE     Distinguishing protein-coding and noncoding genes in the human
            genome
  JOURNAL   Proc Natl Acad Sci U S A 104 (49), 19428-19433 (2007)
   PUBMED   18040051
REFERENCE   4  (bases 1 to 1106)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   5  (bases 1 to 1106)
  AUTHORS   Volz,A., Ehlers,A., Younger,R., Forbes,S., Trowsdale,J.,
            Schnorr,D., Beck,S. and Ziegler,A.
  TITLE     Complex transcription and splicing of odorant receptor genes
  JOURNAL   J Biol Chem 278 (22), 19691-19701 (2003)
   PUBMED   12637542
REFERENCE   6  (bases 1 to 1106)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AJ459873.1 and BC136817.1.
            
            On Mar 12, 2009 this sequence version replaced NM_001005226.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000377173.4/ ENSP00000366378.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-65                AJ459873.1         1-65
            66-1106             BC136817.1         25-1065
FEATURES             Location/Qualifiers
     source          1..1106
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p22.1"
     gene            1..1106
                     /gene="OR2B3"
                     /gene_synonym="6M1-1; OR2B3P; OR6-14; OR6-4"
                     /note="olfactory receptor family 2 subfamily B member 3"
                     /db_xref="GeneID:442184"
                     /db_xref="HGNC:HGNC:8238"
     exon            1..1106
                     /gene="OR2B3"
                     /gene_synonym="6M1-1; OR2B3P; OR6-14; OR6-4"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..1007
                     /gene="OR2B3"
                     /gene_synonym="6M1-1; OR2B3P; OR6-14; OR6-4"
                     /note="olfactory receptor OR6-14; hs6M1-1; olfactory
                     receptor 6-4"
                     /codon_start=1
                     /product="putative olfactory receptor 2B3"
                     /protein_id="NP_001005226.1"
                     /db_xref="CCDS:CCDS34358.1"
                     /db_xref="GeneID:442184"
                     /db_xref="HGNC:HGNC:8238"
                     /translation="MNWENESSPKEFILLGFSDRAWLQMPLFVVLLISYTITIFGNVS
                     IMMVCILDPKLHTPMYFFLTNLSILDLCYTTTTVPHMLVNIGCNKKTISYAGCVAHLI
                     IFLALGATECLLLAVMSFDRYVAVCRPLHYVVIMNYWFCLRMAAFSWLIGFGNSVLQS
                     SLTLNMPRCGHQEVDHFFCEVPALLKLSCADTKPIEAELFFFSVLILLIPVTLILISY
                     GFIAQAVLKIRSAEGRQKAFGTCGSHMIVVSLFYGTAIYMYLQPPSSTSKDWGKMVSL
                     FYGIITSMLNSLIYSLRNKDMKEAFKRLMPRIFFCKK"
ORIGIN      
        1 ataaacaaac attgattgct ttcctatctt acattttttt aggagtgcga aataagtgag
       61 tcatcatgaa ttgggaaaat gagagctccc caaaagagtt tatactactt ggcttctcag
      121 atagggcttg gctacaaatg cccctttttg tggtcctgtt aatatcatac acaatcacca
      181 tatttggcaa tgtgtccatc atgatggtgt gcattctgga tcccaaactt catactccca
      241 tgtatttctt tctcactaat ctctccatct tagatctctg ctataccaca actacagtcc
      301 ctcatatgtt ggtaaatatt ggttgcaaca aaaagaccat cagctatgct ggctgtgtgg
      361 cccacctcat catcttcctg gccctaggtg ctacagagtg tctccttctg gctgttatgt
      421 cctttgacag atatgtggct gtttgcagac ccctccacta tgtagtcatc atgaattatt
      481 ggttctgcct aaggatggca gccttctcat ggctcattgg tttcggcaac tcagtgctgc
      541 agtcttcctt gactcttaac atgccacgct gtggtcacca ggaagtggac cactttttct
      601 gtgaggtgcc tgcacttctc aagttgtcat gtgctgacac aaagcctatt gaggctgagc
      661 tcttcttctt tagtgtacta attcttctaa ttccagtgac attgatcctc atctcctatg
      721 gcttcatagc tcaagcagta ttaaaaatca ggtcagcaga aggacggcaa aaagcatttg
      781 ggacatgtgg gtcccacatg attgtggtgt ccctctttta tggaacagcc atttatatgt
      841 atcttcaacc accttcatcc acctctaagg actggggaaa gatggtttcc ctcttctatg
      901 gaatcatcac atccatgttg aactccctca tctacagcct tagaaataaa gatatgaagg
      961 aggccttcaa gaggctgatg ccaagaatct ttttctgtaa gaaataagaa gtactccatt
     1021 gtgatgagaa tcttcttagt ctttccttat cttcaatgat ggtaatgacc tttgaactca
     1081 ttttcctatt ttccaggctc tggtga
//
