LOCUS       NM_001258285            1548 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 2 subfamily AP member 1
            (OR2AP1), mRNA.
ACCESSION   NM_001258285
VERSION     NM_001258285.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1548)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC009779.18.
            
            On Jul 31, 2020 this sequence version replaced NM_001258285.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641114.1/ ENSP00000493043.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-155               AC009779.18        164576-164730       c
            156-1548            AC009779.18        161586-162978       c
FEATURES             Location/Qualifiers
     source          1..1548
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q13.2"
     gene            1..1548
                     /gene="OR2AP1"
                     /gene_synonym="OR2AP1P"
                     /note="olfactory receptor family 2 subfamily AP member 1"
                     /db_xref="GeneID:121129"
                     /db_xref="HGNC:HGNC:15335"
     exon            1..155
                     /gene="OR2AP1"
                     /gene_synonym="OR2AP1P"
                     /inference="alignment:Splign:2.1.0"
     exon            156..1548
                     /gene="OR2AP1"
                     /gene_synonym="OR2AP1P"
                     /inference="alignment:Splign:2.1.0"
     CDS             351..1280
                     /gene="OR2AP1"
                     /gene_synonym="OR2AP1P"
                     /note="olfactory receptor, family 2, subfamily AP, member
                     1 pseudogene; seven transmembrane helix receptor;
                     olfactory receptor OR12-9"
                     /codon_start=1
                     /product="olfactory receptor 2AP1"
                     /protein_id="NP_001245214.1"
                     /db_xref="CCDS:CCDS58241.1"
                     /db_xref="GeneID:121129"
                     /db_xref="HGNC:HGNC:15335"
                     /translation="MKNKTVLTEFILLGLTDVPELQVAVFTFLFLAYLLSILGNLTIL
                     ILTLLDSHLQTPMYFFLRNFSFLEISFTNIFIPRVLISITTGNKSISFAGCFTQYFFA
                     MFLGATEFYLLAAMSYDRYVAICKPLHYTTIMSSRICIQLIFCSWLGGLMAIIPTITL
                     MSQQDFCASNRLNHYFCDYEPLLELSCSDTSLIEKVVFLVASVTLVVTLVLVILSYAF
                     IIKTILKLPSAQQRTKAFSTCSSHMIVISLSYGSCMFMYINPSAKEGDTFNKGVALLI
                     TSVAPLLNPFIYTLRNQQVKQPFKDMVKKLLNL"
ORIGIN      
        1 gaatatttag gattaaaatc tcacaatagt catttggata gtcaagtcag gaagtatgtt
       61 acctgtttat agcttcattt attttacttc tctggagttg taaagactga aactgatgca
      121 gatgtgaata ttcaaccact ccctgaagac tccagggcaa atgggactgg gaaggatcca
      181 acatcattca aatgggccac tggtctggac tatgtcatca gaggagaagt taatcatcca
      241 tttcattttt ttcttgtcag acttcatccg ttcatttcag agcacctctt cctttctcac
      301 ttttgattac tactctcttt ttcactttga gactcaaaat tttttcaaca atgaaaaata
      361 aaaccgtgtt aactgagttt atccttctgg gtctaacaga tgtccctgaa ctccaggtgg
      421 cagttttcac ctttcttttc cttgcgtatt tactcagcat ccttggaaat ctgactatcc
      481 tcatcctcac cttgctggac tcccaccttc agactcccat gtatttcttt ctccggaact
      541 tctccttctt ggaaatttcc ttcacaaaca tcttcattcc aagggtcctg attagcatca
      601 caacagggaa caagagtatc agctttgctg gctgcttcac tcagtatttc tttgccatgt
      661 tccttggggc tacagagttt taccttctgg ctgccatgtc ctatgaccgc tatgtggcca
      721 tctgcaaacc tctgcattac accaccatca tgagcagcag aatctgcatc cagctgattt
      781 tctgctcttg gctgggtggg ctaatggcta ttataccaac aatcaccctg atgagtcagc
      841 aggacttttg tgcatccaac agactgaatc attacttctg tgactatgag cctcttctgg
      901 aactctcatg ttcagacaca agcctcatag agaaggttgt ctttcttgtg gcatctgtga
      961 ccctggtggt cactctggtg ctagtgattc tctcctatgc attcattatc aagactattc
     1021 tgaagctccc ctctgcccaa caaaggacaa aagccttttc cacatgttct tcccacatga
     1081 ttgtcatctc cctctcttac ggaagctgca tgtttatgta cattaatccc tctgcaaaag
     1141 aaggggatac attcaacaag ggagtagctc tactcattac ttcagttgct cctttgttga
     1201 acccctttat ttacacccta aggaaccaac aggtaaaaca acccttcaag gatatggtca
     1261 aaaagcttct gaatctttaa agaatttaag aattatgcat cgcgacatta ttcacaatag
     1321 caaagacttg gaaccaaccc aaatgtccaa caatgataga ctggattaag aaaatatggc
     1381 acatatacac catggaatac tatgcagcca ttaaaaatga tgagttgatg tcctttgtag
     1441 ggacatggat gaaattggaa atcatcattc tcagtaaact atcacaagaa caaaaaaccg
     1501 aacaccacat attctcactc ataggtggga actgaacaat gagaacac
//
