LOCUS       NM_001004491            1154 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 2 subfamily AK member 2
            (OR2AK2), mRNA.
ACCESSION   NM_001004491 XM_372822
VERSION     NM_001004491.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1154)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC099570.2.
            
            On Jun 16, 2021 this sequence version replaced NM_001004491.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC136816.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000366480.5/
                                                ENSP00000355436.4
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1154              AC099570.2         99928-101081
FEATURES             Location/Qualifiers
     source          1..1154
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q44"
     gene            1..1154
                     /gene="OR2AK2"
                     /gene_synonym="OR1-47; OR2AK1P"
                     /note="olfactory receptor family 2 subfamily AK member 2"
                     /db_xref="GeneID:391191"
                     /db_xref="HGNC:HGNC:19569"
     exon            1..1154
                     /gene="OR2AK2"
                     /gene_synonym="OR1-47; OR2AK1P"
                     /inference="alignment:Splign:2.1.0"
     CDS             145..1107
                     /gene="OR2AK2"
                     /gene_synonym="OR1-47; OR2AK1P"
                     /note="olfactory receptor, family 2, subfamily AK, member
                     1 pseudogene; olfactory receptor OR1-47; olfactory
                     receptor 2AK1"
                     /codon_start=1
                     /product="olfactory receptor 2AK2"
                     /protein_id="NP_001004491.2"
                     /db_xref="CCDS:CCDS31102.2"
                     /db_xref="GeneID:391191"
                     /db_xref="HGNC:HGNC:19569"
                     /translation="MKTGNQSFGTDFLLVGLFQYGWINSLLFVVIATLFTVALTGNIM
                     LIHLIRLNTRLHTPMYFLLSQLSIVDLMYISTTVPKMAVSFLSQSKTIRFLGCEIQTY
                     VFLALGGTEALLLGFMSYDRYVAICHPLHYPMLMSKKICCLMVACAWASGSINAFIHT
                     LYVFQLPFCRSRLINHFFCEVPALLSLVCQDTSQYEYTVLLSGLIILLLPFLAILASY
                     ARVLIVVFQMSSGKGQAKAVSTCSSHLIVASLFYATTLFTYTRPHSLRSPSRDKAVAV
                     FYTIVTPLLNPFIYSLRNKEVTGAVRRLLGYWICCRKYDFRSLY"
ORIGIN      
        1 tgctctaaac atgtagatag ttgccaaaca tgtaagtgaa tatttatttc tgaatgccat
       61 gtcattttac tttctcttaa gggaagtcaa cattattaca tgaacatttc agatgtcatc
      121 tcctttgata ttttggtttc agccatgaaa acaggaaatc aaagttttgg gacagatttt
      181 ctacttgttg gtcttttcca atatggctgg ataaactctc ttctctttgt cgtcattgcc
      241 accctcttta cagttgctct gacaggaaat atcatgctga tccacctcat tcgactgaac
      301 accagactcc acactccaat gtactttctg ctcagtcagc tctccatcgt tgacctcatg
      361 tacatctcca ccacagtgcc caagatggca gtcagcttcc tctcacagag taagaccatt
      421 agatttttgg gctgtgagat tcaaacgtat gtgttcttgg cccttggtgg aactgaagcc
      481 cttctccttg gttttatgtc ttatgatcgc tatgtagcta tctgtcaccc tttacattat
      541 cctatgctta tgagcaagaa gatctgctgc ctcatggttg catgtgcatg ggccagtggt
      601 tctatcaatg ctttcataca tacattgtat gtgtttcagc ttccattctg taggtctcgg
      661 ctcattaacc actttttctg tgaagttcca gctctactat cattggtgtg tcaggacacc
      721 tcccagtatg agtatacagt cctcctgagt ggacttatta tcttgctact accattccta
      781 gccattctgg cttcctatgc tcgtgtgctt attgtggtat tccagatgag ctcaggaaaa
      841 ggacaggcaa aagctgtttc cacttgttcc tcccacctga ttgtggcaag cctgttctat
      901 gcaaccactc tctttaccta cacaaggcca cactccttgc gttccccttc acgggataag
      961 gcggtggcag tattttacac cattgtcaca cctctactga acccatttat ctacagcctg
     1021 agaaataagg aagtgacggg ggcagtgagg agactgttgg gatattggat atgctgtaga
     1081 aaatatgact tcagatctct gtattgattg agcattaaca acataaaaag ctgttcctga
     1141 aaactatctg gaaa
//
