LOCUS       NM_001355235            1873 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 2 subfamily AJ member 1
            (OR2AJ1), mRNA.
ACCESSION   NM_001355235
VERSION     NM_001355235.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1873)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from AC099571.3.
            
            On Aug 5, 2020 this sequence version replaced NM_001355235.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000318244.4/
                                                ENSP00000325078.3
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-280               AC099571.3         140998-141277
            281-1873            AC099571.3         149856-151448
FEATURES             Location/Qualifiers
     source          1..1873
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q44"
     gene            1..1873
                     /gene="OR2AJ1"
                     /gene_synonym="OR2AJ1P; OR2AJ1Q"
                     /note="olfactory receptor family 2 subfamily AJ member 1"
                     /db_xref="GeneID:127608"
                     /db_xref="HGNC:HGNC:15001"
     exon            1..280
                     /gene="OR2AJ1"
                     /gene_synonym="OR2AJ1P; OR2AJ1Q"
                     /inference="alignment:Splign:2.1.0"
     exon            281..1873
                     /gene="OR2AJ1"
                     /gene_synonym="OR2AJ1P; OR2AJ1Q"
                     /inference="alignment:Splign:2.1.0"
     CDS             303..1289
                     /gene="OR2AJ1"
                     /gene_synonym="OR2AJ1P; OR2AJ1Q"
                     /note="olfactory receptor, family 2, subfamily AJ, member
                     1 pseudogene; olfactory receptor OR1-52"
                     /codon_start=1
                     /product="olfactory receptor 2AJ1"
                     /protein_id="NP_001342164.2"
                     /db_xref="CCDS:CCDS91193.1"
                     /db_xref="GeneID:127608"
                     /db_xref="HGNC:HGNC:15001"
                     /translation="MGHQNHTFSSDFILLGLFSSSPTSVVFFLVLFVIFIMSVTENTL
                     MILLIRSDSRLHTPMYFLLSHLSLMDILHVSNIVPKMVTNFLSGSRTISFAGCGFQVF
                     LSLTLLGGECLLLAAMSCDRYVAICHPLRYPILMKEYASALMAGGSWLIGVFNSTVHT
                     AYALQFPFCGSRAIDHFFCEVPAMLKLSCADTTRYERGVCVSAVIFLLIPFSLISASY
                     GQIILTVLQMKSSEARKKSFSTCSFHMIVVTMYYGPFIFTYMRPKSYHTPGQDKFLAI
                     FYTILTPTLNPFIYSFRNKDVLAVMKNMLKSNFLHKKMNRKIPECVFCLFLC"
ORIGIN      
        1 gctacaggac ttccaactgg gaagttgtct ttcatccttt tccttgctcc tttcaaatca
       61 catatcccct tctccctgta aactgtcagc taatcggaag gaaatcgctg aactgagtat
      121 cacccaatgc ctctgagtca ctctcaagga catgacattg aaacaaacat ctgagtagca
      181 tgaacagcag ctggacacca tgagggagga aggggtgttg agcccagtgt gctaaatgtg
      241 aaaggccctg cctggaatgt cctgtgcgga gcggaacgtg gttaaaaaat agagaattca
      301 tgatgggcca tcagaatcac actttcagca gtgatttcat acttttggga ttgttctctt
      361 cttccccaac aagtgtggtc ttcttcttag ttttatttgt cattttcatt atgagtgtaa
      421 cagaaaatac gctcatgatc ctcctcattc gcagtgactc ccgactccac actccaatgt
      481 attttctgct cagccatctc tccttaatgg atatcttgca tgtttccaac atcgttccca
      541 aaatggtcac taactttctg tcaggcagca gaactatttc atttgcaggt tgtgggttcc
      601 aggtatttct gtccctcacc ctcctgggtg gtgagtgcct tctcctggct gcaatgtcct
      661 gtgatcgcta tgtggctatc tgtcacccgc tgcgctatcc gattcttatg aaggagtatg
      721 ccagcgctct catggctgga ggctcctggc tcattggggt tttcaactcc acagtccaca
      781 cagcttatgc actgcagttt cccttctgtg gctctagggc aattgatcac ttcttctgtg
      841 aagtccctgc catgttgaag ttgtcctgtg cagacacaac acgctatgaa cgaggggttt
      901 gtgtaagtgc tgtgatcttc ctgctgatcc ctttctcctt gatctctgct tcttatggcc
      961 aaattattct tactgtcctc cagatgaaat catcagaggc aaggaaaaag tcattttcca
     1021 cttgttcctt ccacatgatt gtggtcacga tgtactatgg gccatttatt tttacatata
     1081 tgagacctaa atcataccac actccaggcc aggataagtt cctggcaata ttctatacga
     1141 tcctcacacc cacactcaac cctttcatct acagctttag gaataaagat gttctggcgg
     1201 tgatgaaaaa tatgctcaaa agtaactttc tgcacaaaaa aatgaatagg aaaattcctg
     1261 aatgtgtgtt ctgtctattt ctatgttaaa tgcctgaagg atactcatga gaggtttcct
     1321 agaaagaaat caaagcttct atcttaccac atataagaag tgaatatttc agaaacattg
     1381 ttaataataa acaataatat gtgtttgtgt tgtaaacacg tacctctaaa aatgtagtgt
     1441 tccttctgtg gtaccaatta taatcatgca acagttacag gaagtagaag ttacccaagg
     1501 cgtcctattc cctaacacca aaattgtaag acttatgaga atatccctaa aaatacagtc
     1561 acacatccat tgtataaaag acaaatccat gtttattttt ataaaacttt gttaaattat
     1621 attgctaaca atcacttatc aaaaattcac aaattccata tgaaatcatt attctttgcc
     1681 tggtttatca acacctttat ttagtaaaat tttacagata cacatatata tgcacacaca
     1741 catatatatg tacacacata tatacagata taagttgtgt taaaattgaa ttactcatcc
     1801 tatgctagaa gcaactatac aatattagat aggaatatca taaaaattgc cttatttcat
     1861 ttatacatac agg
//
