LOCUS       NM_001005276             972 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 2 subfamily AE member 1
            (OR2AE1), mRNA.
ACCESSION   NM_001005276
VERSION     NM_001005276.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 972)
  AUTHORS   Thompson,E.E., Kuttab-Boulos,H., Yang,L., Roe,B.A. and Di Rienzo,A.
  TITLE     Sequence diversity and haplotype structure at the human CYP3A
            cluster
  JOURNAL   Pharmacogenomics J 6 (2), 105-114 (2006)
   PUBMED   16314882
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB065478.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000316368.3/ ENSP00000313936.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..972
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q22.1"
     gene            1..972
                     /gene="OR2AE1"
                     /gene_synonym="OR2AE2"
                     /note="olfactory receptor family 2 subfamily AE member 1"
                     /db_xref="GeneID:81392"
                     /db_xref="HGNC:HGNC:15087"
     CDS             1..972
                     /gene="OR2AE1"
                     /gene_synonym="OR2AE2"
                     /note="olfactory receptor, family 2, subfamily AE, member
                     2; olfactory receptor 2AE2"
                     /codon_start=1
                     /product="olfactory receptor 2AE1"
                     /protein_id="NP_001005276.1"
                     /db_xref="CCDS:CCDS34696.1"
                     /db_xref="GeneID:81392"
                     /db_xref="HGNC:HGNC:15087"
                     /translation="MWQKNQTSLADFILEGLFDDSLTHLFLFSLTMVVFLIAVSGNTL
                     TILLICIDPQLHTPMYFLLSQLSLMDLMHVSTIILKMATNYLSGKKSISFVGCATQHF
                     LYLCLGGAECFLLAVMSYDRYVAICHPLRYAVLMNKKVGLMMAVMSWLGASVNSLIHM
                     AILMHFPFCGPRKVYHFYCEFPAVVKLVCGDITVYETTVYISSILLLLPIFLISTSYV
                     FILQSVIQMRSSGSKRNAFATCGSHLTVVSLWFGACIFSYMRPRSQCTLLQNKVGSVF
                     YSIITPTLNSLIYTLRNKDVAKALRRVLRRDVITQCIQRLQLWLPRV"
     exon            1..972
                     /gene="OR2AE1"
                     /gene_synonym="OR2AE2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtggcaga agaatcagac ctctctggca gacttcatcc ttgaggggct cttcgatgac
       61 tcccttaccc accttttcct tttctccttg accatggtgg tcttccttat tgcggtgagt
      121 ggcaacaccc tcaccattct cctcatctgc attgatcccc agcttcatac accaatgtat
      181 ttcctgctca gccagctctc cctcatggat ctgatgcatg tctccacaat catcctgaag
      241 atggctacca actacctatc tggcaagaaa tctatctcct ttgtgggctg tgcaacccag
      301 cacttcctct atttgtgtct aggtggtgct gaatgttttc tcttagctgt catgtcctat
      361 gaccgctatg ttgccatctg tcatccactg cgctatgctg tgctcatgaa caagaaggtg
      421 ggactgatga tggctgtcat gtcatggttg ggggcatccg tgaactccct aattcacatg
      481 gcgatcttga tgcacttccc tttctgtggg cctcggaaag tctaccactt ctactgtgag
      541 ttcccagctg ttgtgaagtt ggtatgtggc gacatcactg tgtatgagac cacagtgtac
      601 atcagcagca ttctcctcct cctccccatc ttcctgattt ctacatccta tgtcttcatc
      661 cttcaaagtg tcattcagat gcgctcatct gggagcaaga gaaatgcctt tgccacttgt
      721 ggctcccacc tcacggtggt ttctctttgg tttggtgcct gcatcttctc ctacatgaga
      781 cccaggtccc agtgcactct attgcagaac aaagttggtt ctgtgttcta cagcatcatt
      841 acgcccacat tgaattctct gatttatact ctccggaata aagatgtagc taaggctctg
      901 agaagagtgc tgaggagaga tgttatcacc cagtgcattc aacgactgca attgtggttg
      961 ccccgagtgt ag
//
