LOCUS       NM_001001802            4946 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 2 subfamily A member 42
            (OR2A42), mRNA.
ACCESSION   NM_001001802 XM_377995 XM_380067
VERSION     NM_001001802.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4946)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 4946)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC004889.1.
            
            On Aug 11, 2020 this sequence version replaced NM_001001802.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on partial alignments and paralogous comparisons.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641810.1/ ENSP00000493333.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-30                AC004889.1         91191-91220         c
            31-342              AC004889.1         90047-90358         c
            343-4946            AC004889.1         79859-84462         c
FEATURES             Location/Qualifiers
     source          1..4946
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q35"
     gene            1..4946
                     /gene="OR2A42"
                     /note="olfactory receptor family 2 subfamily A member 42"
                     /db_xref="GeneID:402317"
                     /db_xref="HGNC:HGNC:31230"
     exon            1..30
                     /gene="OR2A42"
                     /inference="alignment:Splign:2.1.0"
     exon            31..342
                     /gene="OR2A42"
                     /inference="alignment:Splign:2.1.0"
     exon            343..4946
                     /gene="OR2A42"
                     /inference="alignment:Splign:2.1.0"
     CDS             347..1279
                     /gene="OR2A42"
                     /note="olfactory receptor OR7-16; olfactory receptor
                     OR7-19; olfactory receptor, family 2, subfamily A, member
                     1"
                     /codon_start=1
                     /product="olfactory receptor 2A1/2A42"
                     /protein_id="NP_001001802.2"
                     /db_xref="CCDS:CCDS56515.1"
                     /db_xref="GeneID:402317"
                     /db_xref="HGNC:HGNC:31230"
                     /translation="MGENQTMVTEFLLLGFLLGPRIQMLLFGLFSLFYIFTLLGNGAI
                     LGLISLDSRLHTPMYFFLSHLAVVDIAYTRNTVPQMLANLLHPAKPISFAGCMTQTFL
                     CLSFGHSECLLLVLMSYDRYVAICHPLRYSVIMTWRVCITLAVTSWTCGSLLALAHVV
                     LILRLPFSGPHEINHFFCEILSVLRLACADTWLNQVVIFAACVFFLVGPPSLVLVSYS
                     HILAAILRIQSGEGRRKAFSTCSSHLCVVGLFFGSAIIMYMAPKSRHPEEQQKVFFLF
                     YSFFNPTLNPLIYSLRNGEVKGALRRALGKESHS"
ORIGIN      
        1 tcactgtgga catatacagc tggaacacag gagatgagca tgcaggaggt ttcatggccc
       61 agctcctcca gtgatccctc agctgtcaac caggctgagc acatcagaga ataacacctc
      121 cttttctgag gattctgata cattttcaat cagaaacaga agcaaagatt ctgcagctcc
      181 cacagaaact cccagaaacc ttcaggtgct tcactcttct gagatccttg agtccaaatg
      241 tgggagctaa ccaggttgcc tctttttact ttaccatgaa ttcctcctag acatgttgta
      301 gctcctggtc ttggttaact ttcacatcca ctacaaacat tgggaaatgg gggaaaatca
      361 gacaatggtc acagagttcc tcctactggg atttctcctg ggcccaagga ttcagatgct
      421 cctctttggg ctcttctccc tgttctatat cttcaccctg ctggggaacg gggccatcct
      481 ggggctcatc tcactggact ccagactcca cacccccatg tacttcttcc tctcacacct
      541 ggctgtcgtc gacatcgcct acacccgcaa cacggtgccc cagatgctgg cgaacctcct
      601 gcatccagcc aagcccatct cctttgctgg ttgcatgacg cagacctttc tctgtttgag
      661 ttttggacac agcgaatgtc tcctgctggt gctgatgtcc tacgatcgtt acgtggccat
      721 ctgccaccct ctccgatact ccgtcatcat gacctggaga gtctgcatca ccctggccgt
      781 cacttcctgg acgtgtggct ccctcctggc tctggcccat gtggttctca tcctaagact
      841 gcccttctct gggcctcatg aaatcaacca cttcttctgt gaaatcctgt ctgtcctcag
      901 gctggcctgt gctgacacct ggctcaacca ggtggtcatc tttgcagcct gcgtgttctt
      961 cctggtgggg ccacccagcc tggtgcttgt ctcctactcg cacatcctgg cggccatcct
     1021 gaggatccag tctggggagg gccgcagaaa ggccttctcc acctgctcct cccacctctg
     1081 cgtggtggga ctcttctttg gcagtgccat catcatgtac atggccccca agtcccgcca
     1141 tcctgaggag cagcaaaagg tcttttttct attttacagt tttttcaacc caacacttaa
     1201 ccccctgatt tacagcctga ggaacggaga ggtcaagggt gccctgagga gagcactggg
     1261 caaggaaagt cattcctaac tggtgtgaca tttgactctc cctcctcagt catctcctgg
     1321 aatcttggta ccaaatacca cctaagttca ctactctctt tatatctgag actgaatgaa
     1381 ccaagagact ctgcaaagca ttcctttttc ctgcctggga agtatttagt ttttgatgca
     1441 tttgttatac ttaacatttt ttaatttaag cacttattga gttgagaatg ttggggaaag
     1501 atttattttg tacactgcta tgagtccaga agtttaaaac agacactcca cctgtgactt
     1561 agtcaggtat gctcagtagt agaggaatag cagttattac cagataaagt catatctata
     1621 aaaagttttt aaaaatacag ccacaggcag agactccaga acccattgat acctctgtcc
     1681 attttcatcc tcatttggat gtttcccctc aattgtactt cctttcttat aagcagtaaa
     1741 tgtacctaag tgcctacttc agcttggagg gaaattgatt tttataaaat cctacaaact
     1801 gacaatttct gttgtcagag agagtgaatc cataaacatt cagctggcaa tctgaagcaa
     1861 ttacacaaca aaatccactt tccaacctgc cctgagactg tgatggtcac ttgtttctac
     1921 tcttctcacc tcctccaggg gactgtctat gattgtctct aaataagcac atgctcttca
     1981 cttagaggaa gttagtacca ccacacaact tttcactgct ggggacgaat ggaaagcccc
     2041 acacagagac aattcaatgg aaaaaagcgt tttaataata atgttaatag ttagcattat
     2101 tataaattac tctgcaccat ccactgcaca ttgataggta ctttatagag ataacctcag
     2161 tttatcatta tagccaattc atttcccatt attatcccat tttatagatg tgaacttcaa
     2221 gcagatggta aatgttagac tcatacccaa acaatctggc tcccaagcct tctttactta
     2281 accaggacaa tgtgggactt tattagcaac atttcaaatt aagaataagt ctaaccaatc
     2341 ctaacgtagg atatgttaag tgaatgtggg tttcttcccc atctagaatg tgccatgatg
     2401 aggccaggag agtcagagat tatttatgga aggcttctta tcctgtttga cgagtcctgt
     2461 gggcatggct gcaaaggagg ttaagagatt cagaggaaca cagaacacag acagggtggg
     2521 agtagaggct gttctcaatg agattagaga gtaagtttag aactatactt ggttctgggt
     2581 ggtaagatcc agaacaaaga catctctagt tcacgtacaa cactcacatg ctcacgtaca
     2641 tgcgtgcgcg cacacacaca cacacacata tacgcacagt gcttagtgaa gcactattcc
     2701 aagaacctta caagtaagag ctctttaagt cctcataaaa accctatgag gtagagacta
     2761 ttactactat ttttaggcga gaaaacagaa ctatagagag attatataat ttaaccaatg
     2821 ctcccagcta ataagtacct agtccagaat caaacttagg caatatgact gctgaaccca
     2881 taatcgtaac cattatataa aaatcaaaga gatcatgaaa tttccaaaga tgaagaggag
     2941 gagagatgaa aagcaatttt caatctctag ccaaagatag gcattgggct ccagacagaa
     3001 aagtacttaa agctggggga aaaacaaaca aacaaacaaa caaacaaaca aaaaacagct
     3061 ttttttatac tggtgcgtga aatgagatga ggtggtagca agaaggaact gtgactccaa
     3121 gggtcagaga cggaggagga gcctcttgac gggcaggatg gtgaaaccaa aaacaatgga
     3181 taaaactttt aagttgatgg ttcatcaatt gaagaacatt agaaagtgtt tttgtaaatt
     3241 atctagccgg gcatggcaac gtgtgcctac atccccagct attcgggagg ctgaggcaag
     3301 aggatcactt gagccaggga ttttgaggct gcagtgagcc atgatcgcac cactgcattc
     3361 cagcctgggt gacagagtga gaccttgtct ccaacaataa taacaatgaa ataatttatt
     3421 aaatttttta aaattaccca aactggatat acaatttgta attccattgc tgccgaacag
     3481 tttttaaacg gttgtttagt ttcacggcag atgctgcata ctgcattgca actaacactg
     3541 ggaagggata cattcaagtg gcaggacaaa ggtgaggagc tctaatacca ggggtaggtt
     3601 tcaagggatg aatactcccc tggtaccaga ggagcagcag gaaatcatgg tgtgcagaaa
     3661 ccatgctcag gcggttgcct gtgtggaccc taaattctgt gtgtgcagtc ctctcttagg
     3721 attggcccag gcatccagga agcccacgat gctgcctacc ccttaaatac acaaggtgcg
     3781 taccggaggc cctggttcta gttccagatg taccatttgc tagctgtgtt ttttgcagag
     3841 aagtccctta aactgcttaa gcttcagtcc ttcatctgaa aattatgcat atggaagctg
     3901 tttaggacac cacagagtgc cactgaaaac ccaaagcaag atgcaaatgg acacattttt
     3961 tttctgaaga cttaaaagtg ctatgtgaac ataagataaa ctgttatgat taccctgctg
     4021 tcagaagtta ttttaaacct gtcagggttg ctaaactttc tgatctggaa ccaaaattgc
     4081 tctttaaaca ggaagagcat tggtgctggt aggtcaccta cgcctttgcc ctcatggctt
     4141 ccccatgtcc cccctagagg cacaggaggc cactcactct tggagggcat agctggacca
     4201 ggagcatgag ctgtggccca gactcaggga acctctgtga gtcagctggc aaaggctccc
     4261 ggggagcctg tctctgaatc tggtcctagc ccgttcactt ggaaaaaaca ggagacttct
     4321 cccaaggtca aggaattcag attttggttt tggtttccaa ctttttgtaa tcctcaacct
     4381 gggatttaca gtgcatgtct caattatgtt tcattcattg cttcacaaag ggaaggacaa
     4441 gcactggttc atctctttac acctatacat tcctagcaca gagtgagtac tcacaaaaaa
     4501 catacggaat acatagagga cactttatct gttgacccca tttccaaatt ttcagtgttg
     4561 agccatcttc tgatttctaa acttctttaa atccctctaa ttttaggtca tactacagta
     4621 gaaatttaat tgtagctgat aattattgag cacttactat gtggttggca ctgcataaaa
     4681 tgctttagaa aaattcttac atcaaatatg tggagtaggt actaatacta tcctaacatt
     4741 aaaggggggg gggaaataaa gtttagtgta attaattaat ttattcaagg tcgccaaatc
     4801 attcagtggt agaaacatga atcaagacca ggcagtctga ctgtaaataa attctgagcc
     4861 actctcttgc agaggacctc ctgatattca tctcctgaat ggttggcaac aggcctgttc
     4921 atagtagaca ctcaataaac tttgac
//
