LOCUS       NM_001001659            2199 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 2 subfamily A member 14
            (OR2A14), mRNA.
ACCESSION   NM_001001659 XM_069616
VERSION     NM_001001659.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2199)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 2199)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC091768.4.
            
            On Jul 22, 2020 this sequence version replaced NM_001001659.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641068.1/ ENSP00000493353.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-89                AC091768.4         77750-77838
            90-2199             AC091768.4         83653-85762
FEATURES             Location/Qualifiers
     source          1..2199
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q35"
     gene            1..2199
                     /gene="OR2A14"
                     /gene_synonym="OR2A14P; OR2A6; OST182"
                     /note="olfactory receptor family 2 subfamily A member 14"
                     /db_xref="GeneID:135941"
                     /db_xref="HGNC:HGNC:15084"
     exon            1..89
                     /gene="OR2A14"
                     /gene_synonym="OR2A14P; OR2A6; OST182"
                     /inference="alignment:Splign:2.1.0"
     exon            90..2199
                     /gene="OR2A14"
                     /gene_synonym="OR2A14P; OR2A6; OST182"
                     /inference="alignment:Splign:2.1.0"
     CDS             124..1056
                     /gene="OR2A14"
                     /gene_synonym="OR2A14P; OR2A6; OST182"
                     /note="olfactory receptor, family 2, subfamily A, member
                     14 pseudogene; olfactory receptor, family 2, subfamily A,
                     member 6; olfactory receptor OR7-12; olfactory receptor
                     2A6"
                     /codon_start=1
                     /product="olfactory receptor 2A14"
                     /protein_id="NP_001001659.1"
                     /db_xref="CCDS:CCDS43672.1"
                     /db_xref="GeneID:135941"
                     /db_xref="HGNC:HGNC:15084"
                     /translation="MEGNKTWITDITLPRFQVGPALEILLCGLFSAFYTLTLLGNGVI
                     FGIICLDCKLHTPMYFFLSHLAIVDISYASNYVPKMLTNLMNQESTISFFPCIMQTFL
                     YLAFAHVECLILVVMSYDRYADICHPLRYNSLMSWRVCTVLAVASWVFSFLLALVPLV
                     LILSLPFCGPHEINHFFCEILSVLKLACADTWLNQVVIFAACVFILVGPLCLVLVSYL
                     RILAAILRIQSGEGRRKAFSTCSSHLCVVGLFFGSAIVTYMAPKSRHPEEQQKVLSLF
                     YSLFNPMLNPLIYSLRNAEVKGALRRALRKERLT"
ORIGIN      
        1 cccagtctat ccattctgcc tttcctgtct ttgaggttcc tagcaagccc aagggtatgt
       61 tagaagaaaa gaccacagat tattgtactc tctgaccttc ctgtcctaga tgtccacaag
      121 agcatggaag gcaacaagac atggatcaca gacatcacct tgccgcgatt ccaggttggt
      181 ccagcactgg agattctcct ctgtggactt ttctctgcct tctatacact caccctgctg
      241 gggaatgggg tcatctttgg gattatctgc ctggactgta agcttcacac acccatgtac
      301 ttcttcctct cacacctggc cattgttgac atatcctatg cttccaacta tgtccccaag
      361 atgctgacga atcttatgaa ccaggaaagc accatctcct tttttccatg cataatgcag
      421 acattcttgt atttggcttt tgctcacgta gagtgtctga ttttggtggt gatgtcctat
      481 gatcgctatg cggacatctg ccacccctta cgttacaata gcctcatgag ctggagagtg
      541 tgcactgtcc tggctgtggc ttcctgggtg ttcagcttcc tcctggctct ggtcccttta
      601 gttctcatcc tgagcctgcc cttctgcggg cctcatgaaa tcaaccactt cttctgtgaa
      661 atcctgtctg tcctcaagtt ggcctgtgct gacacctggc tcaaccaggt ggtcatcttt
      721 gcagcctgcg tgttcatcct ggtggggcca ctctgcctgg tgctggtctc ctacttgcgc
      781 atcctggccg ccatcttgag gatccagtct ggggagggcc gcagaaaggc cttctccacc
      841 tgctcctccc acctttgcgt ggtgggactc ttctttggca gcgccattgt cacgtacatg
      901 gcccccaagt cccgccatcc tgaggagcag cagaaagttc tttccctgtt ttacagcctt
      961 ttcaatccaa tgctgaaccc cctgatatat agcctaagga atgcagaggt caagggcgcc
     1021 ctgaggaggg cactgaggaa ggagaggctg acgtgagaca tctcaaaggg aaccatgggg
     1081 agggagcctt gctccctgca aaatatagaa gttggctttt tttttttgtc ttctgctaga
     1141 ataaatgcta ccttaaactg gaatactata gacctataca tataaactga agacacaaat
     1201 cttttagaaa agataggtaa atgcatttat aatactggat aggcataaat tcataaagaa
     1261 gacacaaaag tccctagata taaaattttt aagttcgata aatataggac ctcttcacat
     1321 taatcattgt gctcatcaaa gtcaccatta agaaagaaga aatgcaagcc acaaaccaag
     1381 tgatcgtatg gaaactacat gtacccagaa atggaactat tgttcataca gtacatagaa
     1441 agaactcctt taaatcagca ataaaaaata taaacaacca aattttataa aattagcaaa
     1501 acatgtgaac atatactctt acagaaaata caaggggctg ataaacatac aaatgctgct
     1561 ttccaccatt agtaagcaag gaattgtaaa ttaaaaccac catgagatac tattatatac
     1621 ccactaagat gtctgaaatt tttaatggct tatttatcat tgaggttatt ggaaatctat
     1681 ttctaatatt ggaaatggtc gatactagca gagtttgtgc caatagtagc caagtcacat
     1741 tgagttaaca ggagcatagt acacatcctc aagatcaata attagtgaca cttcctgtga
     1801 agatacacag gttaatgctt aaggctttga gggccatctt ctgcgtcaaa acaactcaac
     1861 tctgacaaaa gcagccatag acaatgtgta aacaaatggg tgtgcccgtg ttccaataaa
     1921 actttatttg taaaaacagg tggctgctgg aatggtgccc agggacagta gtttgtgaac
     1981 ccttgttcta gatcttaaaa ctagcatagt tccagctgat cccactttag agaccctcac
     2041 tgggtggggc ctcagggagc atgtgattag acatgtcttg cagtcaaatt cctgtgatca
     2101 cattgtactt acttgagagt gagacttttc ctcctttgac actttctaaa atatgccatg
     2161 actcaatagc cagtggactg taaatattca tggtttctc
//
