LOCUS       NM_001004459             939 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 1 subfamily S member 2
            (OR1S2), mRNA.
ACCESSION   NM_001004459 XM_166916
VERSION     NM_001004459.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 939)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 939)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP004247.2.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jun 15, 2021 this sequence version replaced NM_001004459.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641683.2/ ENSP00000493223.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-939               AP004247.2         164680-165618       c
FEATURES             Location/Qualifiers
     source          1..939
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.1"
     gene            1..939
                     /gene="OR1S2"
                     /gene_synonym="OR11-231"
                     /note="olfactory receptor family 1 subfamily S member 2"
                     /db_xref="GeneID:219958"
                     /db_xref="HGNC:HGNC:15141"
     CDS             1..939
                     /gene="OR1S2"
                     /gene_synonym="OR11-231"
                     /note="olfactory receptor OR11-231"
                     /codon_start=1
                     /product="olfactory receptor 1S2"
                     /protein_id="NP_001004459.2"
                     /db_xref="CCDS:CCDS31545.2"
                     /db_xref="GeneID:219958"
                     /db_xref="HGNC:HGNC:15141"
                     /translation="MHQENQTTITEFILLGLSNQAEHQNLLFVLFLSMYVVTVVGNGL
                     IIVAISLDIYLHTPMYLFLAYLSFADISSISNSVPKMLVNIQTNSQSISYESCITQMY
                     FSIVFVVTDNLLLGTMAFDHFVAICHPLNYTTFMRARFGTLLTVISWFLSNIIALTHT
                     LLLIQLLFCDHNTLPHFFCDLAPLLKLSCSDTMINELVLFIVGLSVIIFPFVLIFFSY
                     VCIIRAVLGVSSTQGKWKAFSTCGSHLTIALLFYGTTVGVYFFPSSTHPEDTDKIGAV
                     LFTVVTPMMNPFIYSLRNKDMKGALRKLINRKISSL"
     exon            1..939
                     /gene="OR1S2"
                     /gene_synonym="OR11-231"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgcatcaag aaaaccaaac caccatcact gaattcattc tcctgggact ctccaaccag
       61 gctgaacatc aaaacctcct ctttgtgctt ttcctgagta tgtatgtggt cactgtggtt
      121 gggaacgggc tcatcattgt ggctatcagc ttggatatat accttcacac ccccatgtat
      181 ctcttccttg cctacctatc ctttgctgat atttcctcca tttccaactc agtccccaaa
      241 atgctggtga atattcaaac caacagccaa tccatctctt atgagagctg catcacacag
      301 atgtactttt ctattgtgtt tgtcgtcact gacaatttgc ttttggggac catggccttc
      361 gaccactttg tggcgatctg ccaccctctg aactatacaa ctttcatgcg ggccaggttc
      421 ggcactttgc tcacagtcat ctcgtggttc ctcagtaata ttattgctct tacacacacc
      481 cttctgctca ttcaattgct cttctgtgac cacaacactc tcccacactt cttctgtgac
      541 ttggcccctc tgctcaaact gtcctgttca gatacaatga tcaatgagct tgtgttgttt
      601 attgtgggtt tatcagttat catcttcccc tttgtactca tcttcttctc ctatgtctgc
      661 atcatcagag ctgtcctggg agtatcatcc acacagggaa agtggaaagc cttctccact
      721 tgtggctctc acctgacaat tgcattactg ttctacggaa ccactgtagg cgtgtacttt
      781 ttcccctcct ccactcaccc tgaggacact gataagattg gtgctgtcct attcactgtg
      841 gtgacaccca tgatgaaccc cttcatctac agcttgagga ataaggatat gaaaggtgcc
      901 ctgagaaagc tcatcaatag aaaaatttct tccctttga
//
