LOCUS       NM_001004457            1103 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 1 subfamily N member 2
            (OR1N2), mRNA.
ACCESSION   NM_001004457 XM_071151
VERSION     NM_001004457.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1103)
  AUTHORS   Letra,A., Menezes,R., Govil,M., Fonseca,R.F., McHenry,T.,
            Granjeiro,J.M., Castilla,E.E., Orioli,I.M., Marazita,M.L. and
            Vieira,A.R.
  TITLE     Follow-up association studies of chromosome region 9q and
            nonsyndromic cleft lip/palate
  JOURNAL   Am J Med Genet A 152A (7), 1701-1710 (2010)
   PUBMED   20583170
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   2  (bases 1 to 1103)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   3  (bases 1 to 1103)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL359636.17.
            
            On Nov 7, 2018 this sequence version replaced NM_001004457.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC137182.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000373688.3/
                                                ENSP00000362792.3
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1103              AL359636.17        165428-166530
FEATURES             Location/Qualifiers
     source          1..1103
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q33.2"
     gene            1..1103
                     /gene="OR1N2"
                     /gene_synonym="OR9-23"
                     /note="olfactory receptor family 1 subfamily N member 2"
                     /db_xref="GeneID:138882"
                     /db_xref="HGNC:HGNC:15111"
     exon            1..1103
                     /gene="OR1N2"
                     /gene_synonym="OR9-23"
                     /inference="alignment:Splign:2.1.0"
     CDS             101..1051
                     /gene="OR1N2"
                     /gene_synonym="OR9-23"
                     /note="olfactory receptor OR9-23"
                     /codon_start=1
                     /product="olfactory receptor 1N2"
                     /protein_id="NP_001004457.2"
                     /db_xref="CCDS:CCDS35123.2"
                     /db_xref="GeneID:138882"
                     /db_xref="HGNC:HGNC:15111"
                     /translation="MGKPGRVNQTTVSDFLLLGLSEWPEEQPLLFGIFLGMYLVTMVG
                     NLLIILAISSDPHLHTPMYFFLANLSLTDACFTSASIPKMLANIHTQSQIISYSGCLA
                     QLYFLLMFGGLDNCLLAVMAYDRYVAICQPLHYSTSMSPQLCALMLGVCWVLTNCPAL
                     MHTLLLTRVAFCAQKAIPHFYCDPSALLKLACSDTHVNELMIITMGLLFLTVPLLLIV
                     FSYVRIFWAVFVISSPGGRWKAFSTCGSHLTVVLLFYGSLMGVYLLPPSTYSTERESR
                     AAVLYMVIIPTLNPFIYSLRNRDMKEALGKLFVSGKTFFL"
ORIGIN      
        1 cagttctggc cacacagatg catatctgta aattgatcta ataaataaat actgacacat
       61 ggaaggtttt tatctgcgca gatcacacga actacaaggg atgggaaaac caggcagagt
      121 gaaccaaacc actgtttcag acttcctcct tctaggactc tctgagtggc cagaggagca
      181 gcctcttctg tttggcatct tccttggcat gtacctggtc accatggtgg ggaacctgct
      241 cattatcctg gccatcagct ctgacccaca cctccatact cccatgtact tctttctggc
      301 caacctgtca ttaactgatg cctgtttcac ttctgcctcc atccccaaaa tgctggccaa
      361 cattcatacc cagagtcaga tcatctcgta ttctgggtgt cttgcacagc tatatttcct
      421 ccttatgttt ggtggccttg acaactgcct gctggctgtg atggcatatg accgctatgt
      481 ggccatctgc caaccactcc attacagcac atctatgagt ccccagctct gtgcactaat
      541 gctgggtgtg tgctgggtgc taaccaactg tcctgccctg atgcacacac tgttgctgac
      601 ccgcgtggct ttctgtgccc agaaagccat ccctcatttc tattgtgatc ctagtgctct
      661 cctgaagctt gcctgctcag atacccatgt aaacgagctg atgatcatca ccatgggctt
      721 gctgttcctc actgttcccc tcctgctgat cgtcttctcc tatgtccgca ttttctgggc
      781 tgtgtttgtc atctcatctc ctggagggag atggaaggcc ttctctacct gtggttctca
      841 tctcacggtg gttctgctct tctatgggtc tcttatgggt gtgtatttac ttcctccatc
      901 aacttactct acagagaggg aaagtagggc tgctgttctc tatatggtga ttattcccac
      961 gctaaaccca ttcatttata gcttgaggaa cagagacatg aaggaggctt tgggtaaact
     1021 ttttgtcagt ggaaaaacat tctttttatg attagacatc tagacggtga tgtctaatct
     1081 tgatcaaccc ctccctgtct tcc
//
