LOCUS       NM_001004454            2024 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 1 subfamily L member 8
            (OR1L8), mRNA.
ACCESSION   NM_001004454 XM_071150
VERSION     NM_001004454.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2024)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 2024)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL162254.17 and AL359636.17.
            
            On Jan 7, 2021 this sequence version replaced NM_001004454.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            CDS exon combination :: SRR1803614.467560.1 [ECO:0000331]
            RNAseq introns       :: mixed sample support SAMEA2145245,
                                    SAMEA2145743 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641027.1/ ENSP00000493411.1
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-64                AL162254.17        1801-1864           c
            65-186              AL359636.17        190640-190761       c
            187-322             AL359636.17        189082-189217       c
            323-451             AL359636.17        185096-185224       c
            452-2024            AL359636.17        179433-181005       c
FEATURES             Location/Qualifiers
     source          1..2024
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q33.2"
     gene            1..2024
                     /gene="OR1L8"
                     /gene_synonym="OR9-24"
                     /note="olfactory receptor family 1 subfamily L member 8"
                     /db_xref="GeneID:138881"
                     /db_xref="HGNC:HGNC:15110"
     exon            1..64
                     /gene="OR1L8"
                     /gene_synonym="OR9-24"
                     /inference="alignment:Splign:2.1.0"
     exon            65..186
                     /gene="OR1L8"
                     /gene_synonym="OR9-24"
                     /inference="alignment:Splign:2.1.0"
     exon            187..322
                     /gene="OR1L8"
                     /gene_synonym="OR9-24"
                     /inference="alignment:Splign:2.1.0"
     exon            323..451
                     /gene="OR1L8"
                     /gene_synonym="OR9-24"
                     /inference="alignment:Splign:2.1.0"
     exon            452..2024
                     /gene="OR1L8"
                     /gene_synonym="OR9-24"
                     /inference="alignment:Splign:2.1.0"
     CDS             664..1593
                     /gene="OR1L8"
                     /gene_synonym="OR9-24"
                     /note="olfactory receptor OR9-24"
                     /codon_start=1
                     /product="olfactory receptor 1L8"
                     /protein_id="NP_001004454.1"
                     /db_xref="CCDS:CCDS35124.1"
                     /db_xref="GeneID:138881"
                     /db_xref="HGNC:HGNC:15110"
                     /translation="MERINHTSSVSEFILLGLSSRPEDQKTLFVLFLIVYLVTITGNL
                     LIILAIRFNPHLQTPMYFFLSFLSLTDICFTTSVVPKMLMNFLSEKKTISYAGCLTQM
                     YFLYALGNSDSCLLAVMAFDRYVAVCDPFHYVTTMSHHHCVLLVAFSCSFPHLHSLLH
                     TLLLNRLTFCDSNVIHHFLCDLSPVLKLSCSSIFVNEIVQMTEAPIVLVTRFLCIAFS
                     YIRILTTVLKIPSTSGKRKAFSTCGFYLTVVTLFYGSIFCVYLQPPSTYAVKDHVATI
                     VYTVLSSMLNPFIYSLRNKDLKQGLRKLMSKRS"
ORIGIN      
        1 caggatccca tcgaggatat tatattatat tcagtcatcc tgtctccttc ggcttctctt
       61 gactatggag tcttgcactg tcgcccaggc tggagtgccg tggcatgatc tcaactcact
      121 gcaatctccg cctcccaggt tcaagctatt ctcctgcctc agcctcccga gtatctggga
      181 ttacagatcc atcagagaag tgaggtcaca cggcaaccca ctgcccccca aattggagag
      241 acagacaaca aaaatacaaa gaatcacagc ttactggagc agaaacccac aaacagaagc
      301 ctctgcagga atcagtgcta agtccagaag ttcagaggag aaacatgagg aagctgagct
      361 ttggctaaga agcagagttg gaaatcacag atgtgcagaa gatccacttc ttgagacaca
      421 tggaagcaaa ggaaaaacgc tggatacaga gatttcaata taatgccctt atggagccca
      481 tagatttggg aagggaggac cccatcaagg accatgaggt gaacaagcca tcccacaatt
      541 agcacagtag ctaattgtga ccaaacagaa gaaacaaaga cttgctaggt tctcatgatt
      601 ggtgttatga aatcagagca tgttaaatga caaaacttct tgtttataac tgagcccaag
      661 tcaatggaaa gaatcaacca caccagcagt gtctccgagt ttatcctcct gggactctcc
      721 tcccggcctg aggaccaaaa gacactcttt gttctcttcc tcatcgtgta cctggtcacc
      781 ataacaggga acctgctcat catcctggcc attcgcttca acccccatct tcagacccct
      841 atgtatttct tcttgagttt tctgtctctc actgatattt gctttacaac aagcgttgtc
      901 cccaagatgc tgatgaactt cctgtcagaa aagaagacca tctcctatgc tgggtgtctg
      961 acacagatgt attttctcta tgccttgggc aacagtgaca gctgccttct ggcagtcatg
     1021 gcctttgacc gctatgtggc cgtctgtgac cctttccact atgtcaccac catgagccac
     1081 caccactgtg tcctgctggt ggccttctcc tgctcatttc ctcacctcca ctcactcctg
     1141 cacacacttc tgctgaatcg tctcaccttc tgtgactcca atgttatcca ccactttctc
     1201 tgtgacctca gccctgtgct gaaattgtcc tgctcttcca tatttgtcaa tgaaattgtg
     1261 cagatgacag aagcacctat tgttttggtg actcgttttc tctgcattgc tttctcttat
     1321 atacgaatcc tcactacagt tctcaagatt ccctctactt ctgggaaacg caaagccttc
     1381 tccacctgtg gtttttacct caccgtggtg acgctctttt atggaagcat cttctgtgtc
     1441 tatttacagc ccccatccac ctacgctgtc aaggaccacg tggcaacaat tgtttacaca
     1501 gttttgtcat ccatgctcaa tccttttatc tacagcctga gaaacaaaga cctgaaacag
     1561 ggcctgagga agcttatgag caagagatcc taggaagcac cctcttgaaa aactcgtaag
     1621 tggaatctgc tcaacttgga cgtgttttct actggtttct ggtgaacagt caaagctgtt
     1681 ggaagctagc acttctgacc catgtgagac aaggctattg tgggcactta catccattga
     1741 tgatgaccca acaattcggc ctgtatctct taaatcacaa tcgtttcctg tctgtgtctc
     1801 ctctttcttg gaaagattta ttttttccac tttctcattt tccaaaaact gctttaatct
     1861 aatcctttcc ccatgaatat ttcctaaaca aatttctctc cttttattaa ggcagatcct
     1921 ccaaaattct tcacatttca atatattgct gaaaaatgtg taatttgtag ccattgaatg
     1981 tttttgcaaa aaaattgaaa agagaaagaa tgaaggaaga ggag
//
