LOCUS       NM_001004713            5984 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 1 subfamily I member 1
            (OR1I1), mRNA.
ACCESSION   NM_001004713 XM_065050
VERSION     NM_001004713.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5984)
  AUTHORS   Barnes,I.H.A., Ibarra-Soria,X., Fitzgerald,S., Gonzalez,J.M.,
            Davidson,C., Hardy,M.P., Manthravadi,D., Van Gerven,L.,
            Jorissen,M., Zeng,Z., Khan,M., Mombaerts,P., Harrow,J., Logan,D.W.
            and Frankish,A.
  TITLE     Expert curation of the human and mouse olfactory receptor gene
            repertoires identifies conserved coding regions split across two
            exons
  JOURNAL   BMC Genomics 21 (1), 196 (2020)
   PUBMED   32126975
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5984)
  AUTHORS   Grimwood,J., Gordon,L.A., Olsen,A., Terry,A., Schmutz,J.,
            Lamerdin,J., Hellsten,U., Goodstein,D., Couronne,O.,
            Tran-Gyamfi,M., Aerts,A., Altherr,M., Ashworth,L., Bajorek,E.,
            Black,S., Branscomb,E., Caenepeel,S., Carrano,A., Caoile,C.,
            Chan,Y.M., Christensen,M., Cleland,C.A., Copeland,A., Dalin,E.,
            Dehal,P., Denys,M., Detter,J.C., Escobar,J., Flowers,D.,
            Fotopulos,D., Garcia,C., Georgescu,A.M., Glavina,T., Gomez,M.,
            Gonzales,E., Groza,M., Hammon,N., Hawkins,T., Haydu,L., Ho,I.,
            Huang,W., Israni,S., Jett,J., Kadner,K., Kimball,H., Kobayashi,A.,
            Larionov,V., Leem,S.H., Lopez,F., Lou,Y., Lowry,S., Malfatti,S.,
            Martinez,D., McCready,P., Medina,C., Morgan,J., Nelson,K.,
            Nolan,M., Ovcharenko,I., Pitluck,S., Pollard,M., Popkie,A.P.,
            Predki,P., Quan,G., Ramirez,L., Rash,S., Retterer,J., Rodriguez,A.,
            Rogers,S., Salamov,A., Salazar,A., She,X., Smith,D., Slezak,T.,
            Solovyev,V., Thayer,N., Tice,H., Tsai,M., Ustaszewska,A., Vo,N.,
            Wagner,M., Wheeler,J., Wu,K., Xie,G., Yang,J., Dubchak,I.,
            Furey,T.S., DeJong,P., Dickson,M., Gordon,D., Eichler,E.E.,
            Pennacchio,L.A., Richardson,P., Stubbs,L., Rokhsar,D.S.,
            Myers,R.M., Rubin,E.M. and Lucas,S.M.
  TITLE     The DNA sequence and biology of human chromosome 19
  JOURNAL   Nature 428 (6982), 529-535 (2004)
   PUBMED   15057824
REFERENCE   3  (bases 1 to 5984)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC004699.1 and AC004794.1.
            
            On Aug 7, 2020 this sequence version replaced NM_001004713.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000641398.1/
                                                ENSP00000493393.1
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-66                AC004699.1         42908-42973
            67-5984             AC004794.1         6021-11938
FEATURES             Location/Qualifiers
     source          1..5984
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.12"
     gene            1..5984
                     /gene="OR1I1"
                     /gene_synonym="OR19-20; OR1I1P; OR1I1Q"
                     /note="olfactory receptor family 1 subfamily I member 1"
                     /db_xref="GeneID:126370"
                     /db_xref="HGNC:HGNC:8207"
     exon            1..66
                     /gene="OR1I1"
                     /gene_synonym="OR19-20; OR1I1P; OR1I1Q"
                     /inference="alignment:Splign:2.1.0"
     exon            67..5984
                     /gene="OR1I1"
                     /gene_synonym="OR19-20; OR1I1P; OR1I1Q"
                     /inference="alignment:Splign:2.1.0"
     CDS             80..1147
                     /gene="OR1I1"
                     /gene_synonym="OR19-20; OR1I1P; OR1I1Q"
                     /note="olfactory receptor 19-20"
                     /codon_start=1
                     /product="olfactory receptor 1I1"
                     /protein_id="NP_001004713.1"
                     /db_xref="CCDS:CCDS32937.1"
                     /db_xref="GeneID:126370"
                     /db_xref="HGNC:HGNC:8207"
                     /translation="MEPEKQTEISEFFLQGLSEKPEHQTLLFTMFLSTYLVTIIGNAL
                     IILAIITDSHLHTPMYFFLFNLSLVDTLLSSTTVPKMLANIQAQSRAIPFVGCLTQMY
                     AFHLFGTMDSFLLAVMAIDRFVAIVHPQRYLVLMCSPVCGLLLGASWMITNLQSLIHT
                     CLMAQLTFCAGSEISHFFCDLMPLLKLSGSDTHTNELVIFAFGIVVGTSPFSCILLSY
                     IRIFWTVFKIPSTRGKWKAFSTCGLHLTVVSLSYGTIFAVYLQPTSPSSSQKDKAAAL
                     MCGVFIPMLNPFIYSIRNKDMKAALGKLIGKVAVPCPRPEQLLDVYHVPGSLLAARDT
                     EMHPIPYPGGVQSLAGNRDME"
ORIGIN      
        1 ctgggggcgg gggggtacac atatgaatcc ttcccataga catcaggcta accccagcga
       61 tcacagtcac agaccataca tggaaccaga aaagcaaacc gaaatctcag aattcttcct
      121 ccagggactc tcagaaaagc cagagcatca gaccctcctc ttcacaatgt tcctctccac
      181 atacctggtc accatcattg gaaatgccct cattatcctg gccatcatca cggactctca
      241 cctccacaca cccatgtact tctttctctt caacctctca ctcgttgaca ccctattatc
      301 ctccaccacc gtccccaaga tgctagcgaa catccaggct cagagcagag ccatcccctt
      361 tgtgggctgc ctcacccaga tgtatgcctt ccacctgttc gggaccatgg acagctttct
      421 cctggcagta atggccatcg accgcttcgt ggccattgtc cacccacagc gttacttggt
      481 tctcatgtgc tcccctgtct gtgggctgct gctgggagca tcatggatga tcaccaacct
      541 ccagtctctc atacacacct gcctcatggc tcaactgacc ttctgcgccg gctctgaaat
      601 ctcccacttc ttctgtgacc tcatgcccct gctgaagctc tccggctcag acacgcacac
      661 caacgagctg gtgatctttg cttttggcat tgtcgtgggc accagcccat tctcctgcat
      721 ccttctctcg tacatccgca ttttctggac agtctttaag atcccttcta ctcggggcaa
      781 gtggaaagcc ttctccacct gtggcttaca cctcactgtg gtgtcactgt cctatgggac
      841 catctttgct gtgtacttac agcccacatc ccccagctcc tcccagaagg acaaggcagc
      901 cgccctaatg tgtggggtgt tcatccccat gctcaacccc tttatctaca gcatacggaa
      961 caaggatatg aaggcagccc tggggaagct catcggcaaa gtggccgtcc cctgtcctag
     1021 gccagaacag ttattggatg tttatcatgt tccaggatca ctgttggctg ctagggacac
     1081 agagatgcat cccatcccct accctggagg agttcagagt ctagctggga acagagacat
     1141 ggaataaatc cttccagtac aacgtgataa atgtgtcata aagagatgaa caaagtgtat
     1201 gagcacccaa aggaaaggtg tgcattttcc ccaggattta tcttccccaa aaagatcaga
     1261 atagcaagga tcaaactggc ctgaaattag ccctcctgga ggatcagcct tttaggattg
     1321 ctatgtgaat aagagtagtt gaaaacaaga gacgtagcta cactcatttt agtattgaca
     1381 aaggccaggt gtggaagctc aagcctgtga tcccagcatt ttgggaggcc aaggtggaag
     1441 gatcacttga ggccaggagt ttgagaccag cctgggcaac atacagagac cctatctcca
     1501 cacacacaca caaaatcact ttagcaagac atggtggtat acgcctgtag tctcagctaa
     1561 tcaggaggct gaggcaggca gatcatttga gcccaggagt tcaaggttgc agtgagctat
     1621 gactgcacca ctgcacttca gcagtttggg aaactgagca agatctgtca ctcataggta
     1681 gatagataga tagatagata gatagataga tagatagata gatagacaga cagatagata
     1741 gagaggataa gataagatag gtagataggg tggatagata agatatgtag atagatagat
     1801 agatagatag atagatagat agatagatag atagatatac agatagatac atagatagat
     1861 aggatagata ggtaggtagg taggtaggtc aaccgatcga tagatctatc tattgacaga
     1921 cagatagatg attgattgat agatagatca tataagtaga tagatgatag atagatagat
     1981 agatagatag atagatgaga taggtaggta ggtcagtcga tcgattgatc aatcgatcaa
     2041 cagatagatg atagatagat ggatggatag atagagatag aggaggtagg tagatagata
     2101 gatagataga taggtagata cagacagccc atgtattagc cagtgtttcc taagtgttgt
     2161 ggaagaactt tgaaaatatt tgcaagtgag attagctcac gtgctgttcg cttagtcagc
     2221 cagcaagcct cagcctcctg gggggtcttg agacctccac ttgtaactat gactgtggtt
     2281 ggggcttact ttctcaattc ccaacaggct tcctgtctcc ccacaacccc cagtcaaggg
     2341 gactctgatg cagacggtcc atcaatcgta gtttgggaac acagacccta gcctagctcc
     2401 aaaatctatg tgtttcctgt gacattcatc gcctgactct gaacccagta tgattctaca
     2461 cgcagggtca gccacagcag atcaggtggc ccggggcact taaaaagtta gtgttatggg
     2521 ttgaactgtg gctcccaaaa aaagatacgt gggaggccag gcgcagtggc tcacacctgt
     2581 aaactctggc actttgggag gttgagtagg gagaatcatt tgaagctagg agttcaggac
     2641 cagcctgaac aacatagtga gatctcatcc ctacaaaaaa taaaaatgaa aaaagaaaaa
     2701 attacctggg tgtggtggtg tgcacctgtc atcttagtta ctcgggaggc tgagacagga
     2761 ggacctcttg agccaaggag gtcgaggctg catgagctat gttcctgcca ctgcactcca
     2821 gcctgggaaa cagagcaagg ccctgtctgc aaaagtaata ataataaaat aaaaaagata
     2881 tgttgaagtc ctaaccccaa ggacctcaga atgtgaccat atttgaagat agggtgttta
     2941 cagaggtcat tagattacag taaggtcatt aggttggtcc ctaatctgat acgactggcg
     3001 tccttatgaa aaggggagat ttggacacag gcacccacac acatggagac cgccacatga
     3061 agatggaggc agagattggg gtgatgctcc tacaagccaa ggaatgccag ggactgcctg
     3121 cagaccacca gaagccagga gaggcgtgga acaggctatc cctctcagcc ctcagaagga
     3181 accaaggaat caaagctgct gacaactgat cttttttttt tttttttttt tttgagacgg
     3241 agtcttgctc tgtcatcccg gctggatgca gtggcatgat tttggctcac tgcaacctcc
     3301 acctcccagg ttcaagcaat tctcctgcct cagcctccca agtagctggg attacaggca
     3361 cccaccacca cgcccagcta attttgtgtt tttagtagag atgggatttc actatgttgg
     3421 ccagactggt ctcaaactcc tggcctccag tgatctgccc acctcagcct cccaaagtgc
     3481 tgggattaca agcgtgggcc actgcacctg gcccaacacc ttgatctcgg actcttaacc
     3541 tccagaactg taagacaaca aatttctatt gtttaagtca cctagttcat ggtaattttt
     3601 aaattttttt ttcttttaga gacagacagg atctactgtg tcacccaggc tggagtacag
     3661 tggtgcaatc atagctaaag tgcaacctca cctcaaactc ctgggctcaa gcaatcctcc
     3721 tgcctcagcc tcctgagtag ttgggactac aggcctatgc cactgcaatc agctatatat
     3781 atttgtagag acagggtctc actatgttgc ccaggctggt ctcaaactcc cggcctcaag
     3841 agatctgccc tcctcggctt cacaaagtgc tgggattgca ggtgtaaacc accacactcg
     3901 gcctgatttg tggtactttg ttgcaacatt gctagaaaac aaatgcagtt agtttaagaa
     3961 atgtcagcaa cctacaaaac ctacaaagtg tcccagtaca tcctctcaag tttacaattg
     4021 accatgtgtt ctggccaagg gaccctgggc tagaactgga gaaaaggatg aaggatttag
     4081 attgcatgga ttcacttact gggtatcagc atgatgacaa taatgatgat gacaaccgag
     4141 atttattatc tgaacaatgc taactccttt atatgcacaa tctcaataag tgttaagcaa
     4201 cacccctaca aggtaggtgc agaagtaatt gtggttttgc cactgaaagt aacagcaggc
     4261 tgcgcatggt ggctcacacc tgtattccca gcactttggg aggccgaggc gggcagatca
     4321 caaggtcagt agatcgagac catcctgacc aacatggtga aaccccctct ctactaaaaa
     4381 tacgaaaatt aggccgggca cagtggctca tgcctgtaat cccagaactt tgggaggctg
     4441 aggtgggcgg atcatgaggt caggagatca agaccatcct ggctaacatg gtgaaacccc
     4501 atctctacta aaaatacaaa aaattagccg gacatgttgg cgggcacctg tagtcccagc
     4561 tactcgggag gctgaggcag gagaatggcc tgaacccggg aggcggagct tgcagtgagc
     4621 caaggccacg ccactgcacc ccagcctggg tgacagagcg agactcctcc tcaatttaaa
     4681 aaaaaataca aaacttagcc aggcgtggtg gcccacacct gtagtcccag ctacttggga
     4741 ggctgaggca ggagaatggc gtcaacccgg gaggcggagt ttgcgtgagc cgagatcgcc
     4801 ccactgcact ccagcctggg tgacagagcg agactctgtc tcaaaaaaaa aaaaaaaaaa
     4861 aaaaaaaagt ttgtaattta aaagtttgag catcactggg ctagatgggg gtcctgtaga
     4921 taaccgggac ccaaataggc tttaggtaca gagatacagg agaaccagat ttggggtgcc
     4981 gctctagcca ctgtgtccag gagggaacct tcccaaccgc cctaaaagct ctgaaaacta
     5041 cagttagaga agtggccact aggtggcaat aatgtcattt cacaaattgg atttaaaacg
     5101 cttttttttt tttttttttt ttttggtttt tggttgtttt ttttttttcc ccggaaactt
     5161 gtattctagc tgtgaactgg cccaggtcca tggcccttag gtgtaatctc cccctggaag
     5221 ggcacaacag gtgcaaagtt tccatgatga gaaggagcct gtgttgttta aagaaatcac
     5281 ggagactggt gtggcctgag cccagagtga cagggaagct gggtttgcag ggggcccgtg
     5341 gagggcactg ggagtaacac ggtgtgtgga ccacggggag tgggaccatg acaaggttta
     5401 aggaggatag ggggtggggc tgtgcttcag aacgaacctg ccagttatcc atgccataga
     5461 tctggagtca gcaaactttt tctgtcaagg tccaggtcgt caatattgtc agctttaggg
     5521 accttaccat ctccgttgca atgactgaac tctgctgctg tctggcgaaa gcagccatag
     5581 atgagacatc aacgaatggg cttggctgtg ttccactaaa actttgttta taaacacaga
     5641 agcttccatt tcatatcata gtacatgtca taccttgtag cctttgggtt tgttttcaac
     5701 cacttttaaa atgttaaaac tactctaggc caggtgcatt cactcatgcc tgtaatccca
     5761 gcactttgag aggccaaggg aggaggattg cttgaagcca ggagttcgag actggagtgg
     5821 gcaacatagt gagacctccc ccatctctac aaaaattttt taattagctg ggcatggtgg
     5881 tgcatgcctg tagtctcagc tactcaggag gctgaggaag gaggatcact taagcccagg
     5941 aggtcaaggc tgcagtgagc tatgattgca ccaccgcact ccag
//
