LOCUS       NM_001370640            2748 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 1 subfamily F member 1
            (OR1F1), transcript variant 3, mRNA.
ACCESSION   NM_001370640 XM_011522506
VERSION     NM_001370640.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2748)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 2748)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
REFERENCE   3  (bases 1 to 2748)
  AUTHORS   Bernot,A., Heilig,R., Clepet,C., Smaoui,N., Da Silva,C.,
            Petit,J.L., Devaud,C., Chiannilkulchai,N., Fizames,C., Samson,D.,
            Cruaud,C., Caloustian,C., Gyapay,G., Delpech,M. and Weissenbach,J.
  TITLE     A transcriptional Map of the FMF region
  JOURNAL   Genomics 50 (2), 147-160 (1998)
   PUBMED   9653642
REFERENCE   4  (bases 1 to 2748)
  AUTHORS   Rouquier,S., Taviaux,S., Trask,B.J., Brand-Arpon,V., van den
            Engh,G., Demaille,J. and Giorgi,D.
  TITLE     Distribution of olfactory receptor genes in the human genome
  JOURNAL   Nat Genet 18 (3), 243-250 (1998)
   PUBMED   9500546
  REMARK    Erratum:[Nat Genet 1998 May;19(1):102]
REFERENCE   5  (bases 1 to 2748)
  CONSRTM   French FMF Consortium
  TITLE     A candidate gene for familial Mediterranean fever
  JOURNAL   Nat Genet 17 (1), 25-31 (1997)
   PUBMED   9288094
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AJ003147.1.
            
            On Feb 21, 2023 this sequence version replaced NM_001370640.5.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038197.2266826.1,
                                           SRR18074967.3365266.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03465403, SAMN03465404
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000304646.3/
                                                ENSP00000305424.2
            RefSeq Select criteria           :: based on manual assertion,
                                                conservation, expression,
                                                longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-276               AJ003147.1         147433-147708
            277-326             AJ003147.1         148978-149027
            327-426             AJ003147.1         150467-150566
            427-2748            AJ003147.1         163464-165785
FEATURES             Location/Qualifiers
     source          1..2748
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p13.3"
     gene            1..2748
                     /gene="OR1F1"
                     /gene_synonym="OLFMF; OR16-36; OR16-37; OR16-88; OR16-89;
                     OR16-90; OR1F10; OR1F13P; OR1F4; OR1F5; OR1F6; OR1F7;
                     OR1F8; OR1F9; OR3-145; ORL1023"
                     /note="olfactory receptor family 1 subfamily F member 1"
                     /db_xref="GeneID:4992"
                     /db_xref="HGNC:HGNC:8194"
                     /db_xref="MIM:603232"
     exon            1..276
                     /gene="OR1F1"
                     /gene_synonym="OLFMF; OR16-36; OR16-37; OR16-88; OR16-89;
                     OR16-90; OR1F10; OR1F13P; OR1F4; OR1F5; OR1F6; OR1F7;
                     OR1F8; OR1F9; OR3-145; ORL1023"
                     /inference="alignment:Splign:2.1.0"
     exon            277..326
                     /gene="OR1F1"
                     /gene_synonym="OLFMF; OR16-36; OR16-37; OR16-88; OR16-89;
                     OR16-90; OR1F10; OR1F13P; OR1F4; OR1F5; OR1F6; OR1F7;
                     OR1F8; OR1F9; OR3-145; ORL1023"
                     /inference="alignment:Splign:2.1.0"
     exon            327..426
                     /gene="OR1F1"
                     /gene_synonym="OLFMF; OR16-36; OR16-37; OR16-88; OR16-89;
                     OR16-90; OR1F10; OR1F13P; OR1F4; OR1F5; OR1F6; OR1F7;
                     OR1F8; OR1F9; OR3-145; ORL1023"
                     /inference="alignment:Splign:2.1.0"
     exon            427..2748
                     /gene="OR1F1"
                     /gene_synonym="OLFMF; OR16-36; OR16-37; OR16-88; OR16-89;
                     OR16-90; OR1F10; OR1F13P; OR1F4; OR1F5; OR1F6; OR1F7;
                     OR1F8; OR1F9; OR3-145; ORL1023"
                     /inference="alignment:Splign:2.1.0"
     CDS             439..1377
                     /gene="OR1F1"
                     /gene_synonym="OLFMF; OR16-36; OR16-37; OR16-88; OR16-89;
                     OR16-90; OR1F10; OR1F13P; OR1F4; OR1F5; OR1F6; OR1F7;
                     OR1F8; OR1F9; OR3-145; ORL1023"
                     /note="isoform 1 is encoded by transcript variant 3;
                     olfactory receptor, family 1, subfamily F, member 9;
                     olfactory receptor, family 1, subfamily F, member 7;
                     olfactory receptor, family 1, subfamily F, member 6;
                     olfactory receptor, family 1, subfamily F, member 4;
                     olfactory receptor, family 1, subfamily F, member 5;
                     olfactory receptor, family 1, subfamily F, member 10;
                     olfactory receptor, family 1, subfamily F, member 13
                     pseudogene"
                     /codon_start=1
                     /product="olfactory receptor 1F1 isoform 1"
                     /protein_id="NP_001357569.2"
                     /db_xref="GeneID:4992"
                     /db_xref="HGNC:HGNC:8194"
                     /db_xref="MIM:603232"
                     /translation="MSGTNQSSVSEFLLLGLSRQPQQQHLLFVFFLSMYLATVLGNLL
                     IILSVSIDSCLHTPMYFFLSNLSFVDICFSFTTVPKMLANHILETQTISFCGCLTQMY
                     FVFMFVDMDNFLLAVMAYDHFVAVCHPLHYTAKMTHQLCALLVAGLWVVANLNVLLHT
                     LLMAPLSFCADNAITHFFCDVTPLLKLSCSDTHLNEVIILSEGALVMITPFLCILASY
                     MHITCTVLKVPSTKGRWKAFSTCGSHLAVVLLFYSTIIAVYFNPLSSHSAEKDTMATV
                     LYTVVTPMLNPFIYSLRNRYLKGALKKVVGRVVFSV"
     polyA_site      2748
                     /gene="OR1F1"
                     /gene_synonym="OLFMF; OR16-36; OR16-37; OR16-88; OR16-89;
                     OR16-90; OR1F10; OR1F13P; OR1F4; OR1F5; OR1F6; OR1F7;
                     OR1F8; OR1F9; OR3-145; ORL1023"
                     /note="major polyA site"
ORIGIN      
        1 aaggacagga gactaggaag gcggagggag gctgctattg gcagggcctc agtggagacc
       61 tcccggggtc ccgggacgca gacggacggg cctgaatcgc tcgccttggt gaaatgggat
      121 ccagcgctgc caactgcggc aactgcggtt aaaggagacg accccgtgca gcaggaggag
      181 gttatttaga ataaggaaga atgcgccggg ctcattggtc gctacagggg cataaatttt
      241 ttctaggatt ccagagtatg gctgctccag tcccagattc ggctcgactt acagacctca
      301 gcgcaggacg tggacgccct gcaaaggagg acatttcagc ggacggcaga gaatacagat
      361 ttatgccagc gccctgcgga aggagcctct ggcgggtcat ctccatttat gggagatcgc
      421 agagcggatc ccaggcccat gagcgggaca aaccagtcga gtgtctccga gttcctcctc
      481 ctgggactct ccaggcagcc ccagcagcag catctcctct ttgtgttctt cctcagcatg
      541 tacctggcca ctgtcctggg gaacctgctc atcatcctgt ccgtaagcat agactcctgc
      601 ctgcacaccc ccatgtactt cttcctcagc aacctgtctt ttgtggacat ctgcttctcc
      661 ttcaccaccg tccccaagat gctggccaat cacatactcg agactcagac catctccttc
      721 tgtggctgtc tcacacagat gtatttcgtt ttcatgttcg tggacatgga caatttcctc
      781 ctagctgtga tggcctatga ccactttgtc gccgtgtgcc accccttaca ttacacagca
      841 aagatgaccc atcagctctg tgccctgctg gttgctggat tatgggtggt tgccaacctg
      901 aatgtccttc tgcacaccct gctgatggct ccactctcat tctgtgcaga caatgccatc
      961 actcacttct tctgcgatgt gactccccta ctgaaactct cctgctcaga cacacacctc
     1021 aatgaggtca taatccttag tgagggtgcc ctggtcatga tcaccccatt tctttgcatc
     1081 ctggcttctt atatgcacat cacctgcact gtcctgaagg tcccatccac aaagggaagg
     1141 tggaaagcct tctccacctg tggttctcac ctggctgtgg ttctcctctt ctacagcacc
     1201 atcattgctg tgtattttaa ccctctgtcc tcccactcag ctgagaaaga cactatggct
     1261 actgtgttgt atacagtagt gactcccatg ctaaaccctt tcatctacag cctgaggaac
     1321 aggtacttga aaggggctct gaaaaaagta gttggcaggg tggtgttttc tgtctgatga
     1381 aataatcaag actgaatctc attcccaagg aaatttattt ttcaccaatt gagtttaatg
     1441 cagtagttgt ttcattaaat gatgttcttg ctagtgacac acttagtaat tatactaagt
     1501 taaactatta attataattt tttttgagac agggtcatgc tctgtcaccc aggctggagt
     1561 gcagtgccgt gatcttggct cactgcaccc tccatctccc aggctcaagt gatcctcctg
     1621 cctcagcctc ctgagtagct gggaccacag gtgtgtgcca catgcctagc taaatttttt
     1681 tttttttttt tgagacggag tctctctatg tcgccaggct ggatgctgtt gcgggaagtc
     1741 agggaccctg aacagaggga ccagctggag ctgtgtcaga ggaacataaa ttgtgaagat
     1801 ttcattttaa tatggacatg tatcggttcc caaaattaat acttttataa tttcttacgc
     1861 ctgtctttac tgcaatctct gaacataagc tgtgaagatt tcacggacat ttatcagttc
     1921 ccgaaattaa cacttataat ttctcatgcc tgtctttact ttaatctctt aatcctgtta
     1981 tcttcgtaag ctgacgatgt acgtcacctc aggaccactg tgataattct acctaactat
     2041 acaaattgat tgtaaaacat gtgtatttga acaatatgaa atcagtgcac cttgaaaaag
     2101 aacagaataa cagtgatttt agggaacaag ggaagataat cataaggtct gactatctgt
     2161 ggagttgggc agaatggagc catatttttc ttcttgcaga gagcctataa atggacgtgc
     2221 aagtagggat atcactgaat tcttttccta gcaaggaatg ttaataatta agaccttggg
     2281 agaggaatgc actcctcggg ggaggtctat aaatggctgc tctgggagag tctgtcttat
     2341 gcagttgaga taaggactga aatatgccct ggtctcctgc agtaccctca ggcttattag
     2401 tgtggggaaa aaaccccacc ctggtgaatt taaggtcaga cagattctct gctcttgaac
     2461 cctgttttct gttgtttaag atgtttatca agacaatacg tgcacagctg aacatagacc
     2521 cttatctgga ggttttgatt ttgtcctttg ccttgtgatc tctattggct tcagaggcat
     2581 gtgatctttg ttctcctttt tgccctttga cacctgtgat ctctgtgacc tactccctgt
     2641 tcgtacaccc ccaccccttt taaagtcctt aataaaaacc tcctggtttt gcggctcagg
     2701 tgggtcctac caatatggga tgtcaccccc agaggcctag ctgtaaaa
//
