LOCUS       NM_003554                972 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 1 subfamily E member 2
            (OR1E2), mRNA.
ACCESSION   NM_003554 NM_001303278
VERSION     NM_003554.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 972)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 972)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
REFERENCE   3  (bases 1 to 972)
  AUTHORS   Glusman,G., Sosinsky,A., Ben-Asher,E., Avidan,N., Sonkin,D.,
            Bahar,A., Rosenthal,A., Clifton,S., Roe,B., Ferraz,C., Demaille,J.
            and Lancet,D.
  TITLE     Sequence, structure, and evolution of a complete human olfactory
            receptor gene cluster
  JOURNAL   Genomics 63 (2), 227-245 (2000)
   PUBMED   10673334
REFERENCE   4  (bases 1 to 972)
  AUTHORS   Rouquier,S., Taviaux,S., Trask,B.J., Brand-Arpon,V., van den
            Engh,G., Demaille,J. and Giorgi,D.
  TITLE     Distribution of olfactory receptor genes in the human genome
  JOURNAL   Nat Genet 18 (3), 243-250 (1998)
   PUBMED   9500546
  REMARK    Erratum:[Nat Genet 1998 May;19(1):102]
REFERENCE   5  (bases 1 to 972)
  AUTHORS   Ben-Arie,N., Lancet,D., Taylor,C., Khen,M., Walker,N.,
            Ledbetter,D.H., Carrozzo,R., Patel,K., Sheer,D., Lehrach,H. et al.
  TITLE     Olfactory receptor gene cluster on human chromosome 17: possible
            duplication of an ancestral receptor repertoire
  JOURNAL   Hum Mol Genet 3 (2), 229-235 (1994)
   PUBMED   8004088
REFERENCE   6  (bases 1 to 972)
  AUTHORS   Gotschlich,E.C.
  TITLE     Development of polysaccharide vaccines for the prevention of
            meningococcal diseases
  JOURNAL   Monogr Allergy 9, 245-258 (1975)
   PUBMED   804088
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC121106.1.
            
            On or before Jan 6, 2015 this sequence version replaced
            NM_001303278.1, NM_003554.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC121105.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000248384.1/ ENSP00000248384.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-972               BC121106.1         5-976
FEATURES             Location/Qualifiers
     source          1..972
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17p13.2"
     gene            1..972
                     /gene="OR1E2"
                     /gene_synonym="OR17-135; OR17-136; OR17-93; OR1E4; OR1E7;
                     OST529"
                     /note="olfactory receptor family 1 subfamily E member 2"
                     /db_xref="GeneID:8388"
                     /db_xref="HGNC:HGNC:8190"
     CDS             1..972
                     /gene="OR1E2"
                     /gene_synonym="OR17-135; OR17-136; OR17-93; OR1E4; OR1E7;
                     OST529"
                     /note="olfactory receptor, family 1, subfamily E, member
                     4; olfactory receptor, family 1, subfamily E, member 7;
                     olfactory receptor OR17-3; olfactory receptor OR17-17;
                     olfactory receptor 1E4; olfactory receptor
                     17-93/17-135/17-136"
                     /codon_start=1
                     /product="olfactory receptor 1E2"
                     /protein_id="NP_003545.1"
                     /db_xref="CCDS:CCDS11026.1"
                     /db_xref="GeneID:8388"
                     /db_xref="HGNC:HGNC:8190"
                     /translation="MMGQNQTSISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLL
                     IIVLIRLDSHLHTPVYLFLSNLSFSDLCFSSVTMPKLLQNMQNQDPSIPYADCLTQMY
                     FFLYFSDLESFLLVAMAYDRYVAICFPMHYTAICFLLHYTAIMSPMLCLSVVALSWVL
                     TTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLACSDTRVNEWVIFIMGGLILVI
                     PFLLILGSYARIVSSILKVPSSKGICKAFSTCGSHLSVVSLFYGTVIGLYLCPSANSS
                     TLKDTVMAMMYTVVTPMLTPFIYSLRNRDMKGALERVICKRKNPFLL"
     exon            1..972
                     /gene="OR1E2"
                     /gene_synonym="OR17-135; OR17-136; OR17-93; OR1E4; OR1E7;
                     OST529"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgatgggac aaaatcaaac cagcatctca gacttcctgc tcctgggcct gcccatccaa
       61 ccagagcagc aaaacctgtg ctatgccctg ttcttggcca tgtatcttac caccctcctg
      121 gggaacctcc tcatcattgt cctcattcga ctggactccc atctccacac gcctgtgtat
      181 ttgtttctca gcaacttgtc cttctctgac ctctgctttt cctcagtcac aatgcccaaa
      241 ttgctgcaga acatgcagaa ccaagaccca tccatcccct atgcagactg cctgacccaa
      301 atgtacttct tcttgtattt ttcggatcta gagagcttcc tccttgtggc catggcctat
      361 gaccgctatg tggccatctg cttccccatg cactacaccg ccatctgctt cctcctgcac
      421 tacaccgcca tcatgagccc catgctctgt ctctccgtgg tggcgctgtc ctgggtgctg
      481 accaccttcc atgccatgtt acacacttta ctcatggcca ggttgtgttt ttgtgcagac
      541 aatgtgatcc cccacttttt ctgtgatatg tctgctctgc tgaagctggc ctgctctgac
      601 actcgagtta atgaatgggt gatatttatc atgggagggc tcattcttgt catcccattc
      661 ctactcatcc ttgggtccta tgcaagaatt gtctcctcca tcctcaaggt cccttcttct
      721 aagggtatct gcaaggcctt ctctacttgt ggctcccacc tctctgtggt gtcactgttc
      781 tatgggaccg ttattggtct ctacttatgc ccatcagcta atagttctac tctaaaggac
      841 actgtcatgg ctatgatgta cactgtggtg acccctatgc tgaccccctt catctacagc
      901 ctgaggaaca gagacatgaa gggagccctg gaaagggtca tttgtaaaag gaaaaatccc
      961 ttccttctat ga
//
