LOCUS       NM_001396106            3009 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 14 subfamily L member 1
            (OR14L1), mRNA.
ACCESSION   NM_001396106
VERSION     NM_001396106.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3009)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL606804.11.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2142586
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000641545.1/ ENSP00000502618.1
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-258               AL606804.11        175083-175340
            259-3009            AL606804.11        177562-180312
FEATURES             Location/Qualifiers
     source          1..3009
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q44"
     gene            1..3009
                     /gene="OR14L1"
                     /gene_synonym="OR1-35; OR1-36; OR14L1P; OR5AV1; OR5AV1P"
                     /note="olfactory receptor family 14 subfamily L member 1"
                     /db_xref="GeneID:127617"
                     /db_xref="HGNC:HGNC:15023"
     exon            1..258
                     /gene="OR14L1"
                     /gene_synonym="OR1-35; OR1-36; OR14L1P; OR5AV1; OR5AV1P"
                     /inference="alignment:Splign:2.1.0"
     CDS             222..1199
                     /gene="OR14L1"
                     /gene_synonym="OR1-35; OR1-36; OR14L1P; OR5AV1; OR5AV1P"
                     /note="olfactory receptor, family 5, subfamily AV, member
                     1 pseudogene; olfactory receptor OR1-35 pseudogene;
                     olfactory receptor OR1-36; putative olfactory receptor
                     5AV1; putative olfactory receptor 14L1; olfactory receptor
                     family 14 subfamily L member 1 pseudogene"
                     /codon_start=1
                     /product="olfactory receptor 14L1"
                     /protein_id="NP_001383035.1"
                     /db_xref="CCDS:CCDS91192.1"
                     /db_xref="GeneID:127617"
                     /db_xref="HGNC:HGNC:15023"
                     /translation="MAQFNKNQLIACRRNGTTTSDFNQTEVAEFFLMGFSNSWDIQIV
                     HAALFFLVYLAAVIGNLLIIILTTLDVHLQTPMYFFLRNLSFLDFCYISVTIPKSIVS
                     SLTHDTSISFFGCALQAFFFMDLATTEVAILTVMSYDRYMAICRPLHYEVIINQGVCL
                     RMMAMSWLSGVICGFMHVIATFSLPFCGRNRIRQFFCNIPQLLSLLDPKVITIEIGVM
                     VFGTSLVIISFVVITLSYMYIFSVIMRIPSKEGRSKTFSTCIPHLVVVTLFMISGSIA
                     YVKPISNSPPVLDVFLSAFYTVVPPTLNPVIYSLRNRDMKAALRRQCGP"
     exon            259..3009
                     /gene="OR14L1"
                     /gene_synonym="OR1-35; OR1-36; OR14L1P; OR5AV1; OR5AV1P"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2126..2131
                     /regulatory_class="polyA_signal_sequence"
                     /gene="OR14L1"
                     /gene_synonym="OR1-35; OR1-36; OR14L1P; OR5AV1; OR5AV1P"
                     /note="hexamer: ATTAAA"
     polyA_site      2158
                     /gene="OR14L1"
                     /gene_synonym="OR1-35; OR1-36; OR14L1P; OR5AV1; OR5AV1P"
                     /note="major polyA site"
ORIGIN      
        1 caaatattga atcacagcta aatggaaacc agatgtggca ctcatcaagt ttatattttt
       61 gaatcaggga gaagataaag acatttgcag ttgcaacttg gaggctacag ccacattgtt
      121 agattagggc atttttcaat tttatctgat atgttcaggt aaaccaaggc tccttctcaa
      181 agaaacagaa gtttgaaatt ttgaatgact ggagttgctc aatggcccag ttcaacaaaa
      241 atcagctcat agcatgcaga agaaatggaa cgaccacaag tgattttaac caaactgaag
      301 ttgctgaatt tttcctcatg ggattttcga attcctggga tattcagatt gtacatgctg
      361 ctctattctt cctagtttac ctggcagctg tcataggaaa tctcctaatc atcatactta
      421 ccactctgga tgttcacctc caaaccccaa tgtatttctt tttgagaaac ttgtctttct
      481 tagatttttg ttacatctct gtcacaattc caaaatctat tgttagttcc ttgactcatg
      541 atacttccat ttctttcttt gggtgtgctc tgcaagcctt ctttttcatg gacttggcaa
      601 ctacggaggt agccatcctt acagtgatgt cctatgaccg ctatatggcc atctgccggc
      661 ctttacatta tgaggtcatc ataaaccaag gtgtctgtct gaggatgatg gccatgtcgt
      721 ggctcagtgg ggtgatctgt ggattcatgc atgtgatagc aacattctca ttaccattct
      781 gtgggcgcaa tagaatacgt caatttttct gtaatattcc acagctccta agcctcttag
      841 accccaaagt aattaccatt gagattggag tcatggtttt tggtacaagt cttgtgataa
      901 tctcctttgt tgtaattact ctctcctaca tgtacatttt ttctgtcatc atgaggattc
      961 cttctaagga gggtagatca aaaacatttt ctacctgcat tccacatctt gtggttgtaa
     1021 cactctttat gatatctggc agcattgcct atgtgaagcc aatttcaaat tctccccccg
     1081 ttctggatgt tttcctgtct gcgttctaca cagtcgtgcc cccgaccctg aaccccgtca
     1141 tctatagtct gaggaatagg gacatgaagg cagccctgag aaggcagtgt ggtccctgag
     1201 aaggcagtgt ggtatgctag atgaagaatt tgattacgga ccagactctt gaactcttgc
     1261 tctaatcagg caatttgtaa actctctggg tttatatttt caattgattg ctgagctctt
     1321 tcttgatttt taaattaaat tcagctatag tttaccatac taaccatatt tgggtgaatt
     1381 caaccttaga atgcactaaa aggtacttcg gggtgttcaa aacattagaa cttgtgcttt
     1441 tattcatttt tatgagttgt agatctcaaa attttataaa ttatattgta ctcagtaata
     1501 caacatatta attaatataa aagtgaatta ctaatataaa tgaattacta ccgtatgtgt
     1561 atattaatta cagcagaaca agatcatatg gattaaaaac aaccaaatgg aaaataaaca
     1621 taaggtaaca gtgtgtgctc agaatttctt cagcattata aaggatggtc aaataggcta
     1681 gagaccagtg ttctgggagc atatctattg ggtgagatga aatatatgca ataatatcac
     1741 aaactataaa ggttcacata tgtttatggt gctgtgtata ggaaggttca cagaggagaa
     1801 atgtcatttt cattaaacac aatattatgt taagctaact aaaatcttct tccatttttc
     1861 ctctgcatag gaaagtatga actgaaagtt attatgcatt attcccagag tgcttttatg
     1921 tgtattctat ctatataaat attcatctat aaaatgcata gcatcatttt ataaattaat
     1981 acttaaacta taatataaat agcatcctac cttagttatc ctttttaaag tcctttaaat
     2041 tgtattttta gttgacaaat aaaaataatt atatatgcct atggggtaaa agtgatgttt
     2101 taatacatgt ttgcaatgtg gaatgattaa atcaggcaat gtaatatatc acctgaaaca
     2161 tttgtcattc atttgtggtg acattgttta aaatcctctt ttaactgttt tgaaacacac
     2221 aatacattgg tatgaactag attaatcttg ctgtgcaata gatcaccaga gcttatcctt
     2281 cctgtctaac tggaactctg tgctctccga ccaacatttc ccctttacca gtctaccatc
     2341 acccttgcct ccatcttctg gtcagcacca ttctactctg tatttttatg agtttgactt
     2401 tttcagattc cacatataag tgagatcctg tggtatttgt ctctctgtga ctggcttatt
     2461 tcacgtaaca tgatgtcttc tctaggttca tccatattgt caccaatgac agaatttcat
     2521 gttttttttc aaggctgaat agtattccat tgtgtgtgta tactacattt taaaaatcca
     2581 tttgtccatg gtggacactt agattgattc catatttcgg ctattgtaat gccgcaatgc
     2641 acatggaaat acagacatgc ctttgaccta ctgattccag ttctttggat agatgcaagc
     2701 gtacctcatt gtattgcact tcatttgctg aatttcacaa atattgcatt ttttataaat
     2761 caaaggtttt tggtaacttt gcattgggca agtctattgg caccattttt ctgacagcgt
     2821 gtgctcactt cacgtctgtg tgtcaccttt tagtgattct cacaatattt caaacttttt
     2881 cattattgtt atgtctgttt tggtgatctg tgatcagtga tgttcaatgt tactattgta
     2941 tttgtttcgg ggagccatga actgttctca tataagatga taaacttaat aagtgtgtgt
     3001 gttctgact
//
