LOCUS       NM_001004734            4520 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 14 subfamily I member 1
            (OR14I1), mRNA.
ACCESSION   NM_001004734 XM_005273132 XM_377645
VERSION     NM_001004734.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4520)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 4520)
  AUTHORS   Barnes,I.H.A., Ibarra-Soria,X., Fitzgerald,S., Gonzalez,J.M.,
            Davidson,C., Hardy,M.P., Manthravadi,D., Van Gerven,L.,
            Jorissen,M., Zeng,Z., Khan,M., Mombaerts,P., Harrow,J., Logan,D.W.
            and Frankish,A.
  TITLE     Expert curation of the human and mouse olfactory receptor gene
            repertoires identifies conserved coding regions split across two
            exons
  JOURNAL   BMC Genomics 21 (1), 196 (2020)
   PUBMED   32126975
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CR589904.4, AL672295.15 and AC098483.2.
            
            On Aug 2, 2023 this sequence version replaced NM_001004734.3.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1163657.438533.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA2157437
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000695265.1/ ENSP00000511782.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-64                CR589904.4         226-289             c
            65-159              AL672295.15        8442-8536           c
            160-218             AL672295.15        5378-5436           c
            219-333             AC098483.2         161244-161358       c
            334-4520            AC098483.2         153930-158116       c
FEATURES             Location/Qualifiers
     source          1..4520
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q44"
     gene            1..4520
                     /gene="OR14I1"
                     /gene_synonym="OR5BU1; OR5BU1P"
                     /note="olfactory receptor family 14 subfamily I member 1"
                     /db_xref="GeneID:401994"
                     /db_xref="HGNC:HGNC:19575"
                     /db_xref="MIM:618516"
     exon            1..64
                     /gene="OR14I1"
                     /gene_synonym="OR5BU1; OR5BU1P"
                     /inference="alignment:Splign:2.1.0"
     exon            65..159
                     /gene="OR14I1"
                     /gene_synonym="OR5BU1; OR5BU1P"
                     /inference="alignment:Splign:2.1.0"
     exon            160..218
                     /gene="OR14I1"
                     /gene_synonym="OR5BU1; OR5BU1P"
                     /inference="alignment:Splign:2.1.0"
     exon            219..333
                     /gene="OR14I1"
                     /gene_synonym="OR5BU1; OR5BU1P"
                     /inference="alignment:Splign:2.1.0"
     exon            334..4520
                     /gene="OR14I1"
                     /gene_synonym="OR5BU1; OR5BU1P"
                     /inference="alignment:Splign:2.1.0"
     CDS             354..1289
                     /gene="OR14I1"
                     /gene_synonym="OR5BU1; OR5BU1P"
                     /note="olfactory receptor, family 5, subfamily BU, member
                     1 pseudogene; olfactory receptor 5BU1"
                     /codon_start=1
                     /product="olfactory receptor 14I1"
                     /protein_id="NP_001004734.1"
                     /db_xref="CCDS:CCDS31125.1"
                     /db_xref="GeneID:401994"
                     /db_xref="HGNC:HGNC:19575"
                     /db_xref="MIM:618516"
                     /translation="MDNLTKVTEFLLMEFSGIWELQVLHAGLFLLIYLAVLVGNLLII
                     AVITLDQHLHTPMYFFLKNLSVLDLCYISVTVPKSIRNSLTRRSSISYLGCVAQVYFF
                     SAFASAELAFLTVMSYDRYVAICHPLQYRAVMTSGGCYQMAVTTWLSCFSYAAVHTGN
                     MFREHVCRSSVIHQFFRDIPHVLALVSCEVFFVEFLTLALSSCLVLGCFILMMISYFQ
                     IFSTVLRIPSGQSRAKAFSTCSPQLIVIMLFLTTGLFAALGPIAKALSIQDLVIALTY
                     TVLPPFLNPIIYSLRNKEIKTAMWRLFVKIYFLQK"
     regulatory      4501..4506
                     /regulatory_class="polyA_signal_sequence"
                     /gene="OR14I1"
                     /gene_synonym="OR5BU1; OR5BU1P"
                     /note="hexamer: AATAAA"
     polyA_site      4520
                     /gene="OR14I1"
                     /gene_synonym="OR5BU1; OR5BU1P"
                     /note="major polyA site"
ORIGIN      
        1 cagcagagca ctaggagaac agcaggccca catcattctg gctttggcat ttgctctgag
       61 tgagccatga aagacatgcc tgcttcccct tcaccttcca ccgtgattgt aagtttcctg
      121 aggcccccca gccatgcttc ctgtacagcc tgcagaaccg tctgcttgtg tgcatctctt
      181 catttcaatg gctacgtcac gaatacctgc aagaaactat aatacattac aaggaattgg
      241 ccacgtggca gttttgtaga attttacatc taccgatagc aagctaaccc gggagatagt
      301 atactcctgt acactgctga ttctgctgga aggatcacag atttccctgc caaatggaca
      361 atctcacaaa agtgacagaa ttcctgctga tggagttttc tggtatctgg gagctgcagg
      421 tgctgcacgc cgggctgttt ctgctgattt atctggcagt gctggtgggg aacctgctca
      481 tcattgcagt catcactctc gatcagcatc ttcacacacc catgtacttc ttcctgaaga
      541 acctctccgt tttggatctg tgctacatct cagtcactgt gcctaaatcc atccgtaact
      601 ccctgactcg cagaagctcc atctcttatc ttggctgtgt ggctcaagtc tattttttct
      661 ctgcctttgc atctgctgag ctggccttcc ttactgtcat gtcttatgac cgctatgttg
      721 ccatttgcca ccccctccaa tacagagccg tgatgacatc aggagggtgc tatcagatgg
      781 cagtcaccac ctggctaagc tgcttttcct acgcagccgt ccacactggc aacatgtttc
      841 gggagcacgt ttgcagatcc agtgtgatcc accagttctt ccgtgacatc cctcatgtgt
      901 tggccctggt ttcctgtgag gttttctttg tagagttttt gaccctggcc ctgagctcat
      961 gcttggttct gggatgcttt attctcatga tgatctccta tttccaaatc ttctcaacgg
     1021 tgctcagaat cccttcagga cagagtcgag caaaagcctt ctccacctgc tccccccagc
     1081 tcattgtcat catgctcttt cttaccacag ggctctttgc tgccttagga ccaattgcaa
     1141 aagctctgtc cattcaggat ttagtgattg ctctgacata cacagttttg cctcccttcc
     1201 tcaatcccat catatatagt cttaggaata aggagattaa aacagccatg tggagactct
     1261 ttgtgaagat atattttctg caaaagtaga acatcctggt ctttactata gaagatctgc
     1321 aacaaaaccc caaaaaagca taaatacttt atgacaaaaa aagatgaaaa aattgttgat
     1381 gaaatgatga aaaatcctga aaaaaaaaac ctgttgaatg ggagaaagac aatatttgca
     1441 ctactatatg tagatagaaa tgcaaatgtt tcttcaaaaa ctaaaagtat aaaagtataa
     1501 aagtaccttc ataaaatatt tcaaggttgt gtaactgcag cttgttgtgg tgatttattc
     1561 cttcccattc cacacatgtt cgaactgctt taattacctc atcttgaacc tgtagccttg
     1621 cactcctgtt agtatgaatt ttttggaaga ggacacacac atacacacac acacacacac
     1681 acacacacac gcacacagtt ttagtacctg atttagccag tcaacaaaaa agaacataaa
     1741 acaagcagaa gggttattag aacaggaacg tatgttttag attttgccaa atattttaag
     1801 gatatttctc tttcacttag ttatttttag aaatctgtca ggaaattaac acaatttcca
     1861 tcaatgcatc tactgagatt gtcactgagt gcctcagttt ctgcatttgt gttagtattc
     1921 aatgtgttga tagaaacgga tctctttcct gggttttagt gcctcagttt ctacacctgt
     1981 gttaatattc aatgtgttaa tacatacaga gctctttcct gggtctgagt tcttggtcac
     2041 tgctggtgat tatcatcatc gccattgtca ttattttgtc agaacacctg agcgtgagtc
     2101 ccttggcaca tgggctgtct gccattctca ggtgactggg ctcgtgaaat gtacactggc
     2161 tattcctgat tttcacttga tgggatggga agaggattcg tggaaacact gatattctta
     2221 gttggttcag gataagagtc ttgatgtgtg aactgtcatt agcccatcgc agttgtgtgt
     2281 gaggctgacc tctccattag gcactggact ttacatccca aatctcactt ttactttcca
     2341 gagagattgc aaacaattgg gaaaatacaa taaaacataa aattctgtaa atataattct
     2401 tcgatatgct gccaaataaa aatttgtaaa attatttttt ctcattttta actatgcttt
     2461 tgtagttatc aatgtaatag atgtttattg ctttaaatgt ctttcttaaa aactgtcctg
     2521 ctttaatttt ataaaacaag gaaaaaagtt actcaaagtg ctacaacaca ggagaaagaa
     2581 ttctttgctt agacctatct atttgcaact attttatata aaattttact tgaatgctta
     2641 atatgtgttt tttcctgttc ttgaaagtac atttaaaaca ttaaatattg tttataattc
     2701 taaatgaatg taaatgtttt attgcataat aaaacctttg ttattaagct atcactgttt
     2761 ttctctcata agatgaacat ctgaaactat aagataattt gccatggatt aatattttta
     2821 cttaaataca gtcctagata agcaagtact ttcaccctca gtcttatgac cctgatgtca
     2881 gagaagccaa tggcccagga tggggaaaat gtgctagctt tcttcagctt ctagacctga
     2941 aatttatgga ggtggactca ggaccagcta tacctgataa ggctcaaatg acacctgtcc
     3001 caccagagca ggtgtgagtg ttcctgagtg actactcagg gttcttgagg tcaaggacta
     3061 ttttaaggga attttaggga gcaagttgac tcatcactta atgaaagagg caacagggct
     3121 tctaagaaag acaagcacat tataaatggt ttttaatccc ttttaatatt aagtagtata
     3181 ataaagcaca tagtataata tagcatatag ctatattaca tatattagta ctaaacatac
     3241 taatatatat tacaatatat attatattag tactaaacat caagcgacag aacatcacca
     3301 tcacggaagc cctcttgcca ctcctcccaa tcagcacaca ctccccacca aaaatattaa
     3361 cattattcta attttttaat gcttacgttg aactttaagt attcagaaaa gctgcaaaat
     3421 ttgtacagag tttttatgta gtgctcaccc agcttctcct aattttatac agagtttcac
     3481 ttatgtactt gtgtcattca tatttttctt gatccagagc ccctggcatt caacatttcc
     3541 attaagtaaa tttctagggt tgtaccattt ggggcaggag tagctgctca cctacatgaa
     3601 gtagttacaa ggatcaggat ctaacagctt tttatacaaa ttttagacaa gcctcctatt
     3661 tgaactgttt agaggtactt gattacttca acttcaagct tttggaggga ttcttctagt
     3721 ataattctgc aagcttctga gctgcttcta tgaccacatt aatattcagc ttttttagat
     3781 ctaagaagtc caattctaat tatttttttt tcagcctcca aaaatttctt gctgttatct
     3841 tctttcccaa actgttggcc tttgtgtatt tatgctttaa atataatagt tccttcagac
     3901 aatggtaaaa actcttgtct aaaaaaagaa atctgaaaat ttcttgtgtt ctctgccttt
     3961 atttttgaat gatactttag ctggatttag aattaaggct ttgtaggtaa cctgaaatta
     4021 tttcatagca catacaacaa ctataattaa tgaaatatgc gtgtaattta aaaatagaat
     4081 taaaacttca taaatttctt aacattttcc tttgagactt cctgtttgtc ctgtggatta
     4141 tttagaaaca tattgtttaa tttccaagta gttacagatt tttccagttg ttttcgtgta
     4201 attgacttcc aatttgattc agtgttgcca gagaaaacat tgcacatgat ttagaatctt
     4261 ttaaatttgt taaggtttat ttaatgatct gtgaaatggt ctatcttgct gactattcat
     4321 gagtctttga aataaaagta tattctgatg ttgaatggaa tgtcctcaaa gacattaaat
     4381 ctgttatcac aacatcccct gtggacaccc tcatgactac attagatacc ttagcttatt
     4441 tatatgttcc tgccttattg tcctttttgt cattatgtag tagctctata aaatatttgg
     4501 aataaaatat tgaatgcaaa
//
