LOCUS       NM_001005487            2568 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 13 subfamily G member 1
            (OR13G1), mRNA.
ACCESSION   NM_001005487 XM_497748
VERSION     NM_001005487.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2568)
  AUTHORS   Barnes,I.H.A., Ibarra-Soria,X., Fitzgerald,S., Gonzalez,J.M.,
            Davidson,C., Hardy,M.P., Manthravadi,D., Van Gerven,L.,
            Jorissen,M., Zeng,Z., Khan,M., Mombaerts,P., Harrow,J., Logan,D.W.
            and Frankish,A.
  TITLE     Expert curation of the human and mouse olfactory receptor gene
            repertoires identifies conserved coding regions split across two
            exons
  JOURNAL   BMC Genomics 21 (1), 196 (2020)
   PUBMED   32126975
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2568)
  AUTHORS   Koch,W., Hoppmann,P., Schomig,A. and Kastrati,A.
  TITLE     Variations of specific non-candidate genes and risk of myocardial
            infarction: a replication study
  JOURNAL   Int J Cardiol 147 (1), 38-41 (2011)
   PUBMED   19709766
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   3  (bases 1 to 2568)
  AUTHORS   Yoshida,T., Kato,K., Fujimaki,T., Yokoi,K., Oguri,M., Watanabe,S.,
            Metoki,N., Yoshida,H., Satoh,K., Aoyagi,Y., Nishigaki,Y.,
            Tanaka,M., Nozawa,Y. and Yamada,Y.
  TITLE     Association of a polymorphism of the apolipoprotein E gene with
            chronic kidney disease in Japanese individuals with metabolic
            syndrome
  JOURNAL   Genomics 93 (3), 221-226 (2009)
   PUBMED   19056482
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   4  (bases 1 to 2568)
  AUTHORS   van der Net,J.B., Janssens,A.C., Defesche,J.C., Kastelein,J.J.,
            Sijbrands,E.J. and Steyerberg,E.W.
  TITLE     Usefulness of genetic polymorphisms and conventional risk factors
            to predict coronary heart disease in patients with familial
            hypercholesterolemia
  JOURNAL   Am J Cardiol 103 (3), 375-380 (2009)
   PUBMED   19166692
  REMARK    GeneRIF: Observational study of gene-disease association, gene-gene
            interaction, and gene-environment interaction. (HuGE Navigator)
REFERENCE   5  (bases 1 to 2568)
  AUTHORS   Luke,M.M., O'Meara,E.S., Rowland,C.M., Shiffman,D., Bare,L.A.,
            Arellano,A.R., Longstreth,W.T. Jr., Lumley,T., Rice,K., Tracy,R.P.,
            Devlin,J.J. and Psaty,B.M.
  TITLE     Gene variants associated with ischemic stroke: the cardiovascular
            health study
  JOURNAL   Stroke 40 (2), 363-368 (2009)
   PUBMED   19023099
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   6  (bases 1 to 2568)
  AUTHORS   van der Net,J.B., Oosterveer,D.M., Versmissen,J., Defesche,J.C.,
            Yazdanpanah,M., Aouizerat,B.E., Steyerberg,E.W., Malloy,M.J.,
            Pullinger,C.R., Kastelein,J.J., Kane,J.P. and Sijbrands,E.J.
  TITLE     Replication study of 10 genetic polymorphisms associated with
            coronary heart disease in a specific high-risk population with
            familial hypercholesterolemia
  JOURNAL   Eur Heart J 29 (18), 2195-2201 (2008)
   PUBMED   18599554
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   7  (bases 1 to 2568)
  AUTHORS   Shiffman,D., O'Meara,E.S., Bare,L.A., Rowland,C.M., Louie,J.Z.,
            Arellano,A.R., Lumley,T., Rice,K., Iakoubova,O., Luke,M.M.,
            Young,B.A., Malloy,M.J., Kane,J.P., Ellis,S.G., Tracy,R.P.,
            Devlin,J.J. and Psaty,B.M.
  TITLE     Association of gene variants with incident myocardial infarction in
            the Cardiovascular Health Study
  JOURNAL   Arterioscler Thromb Vasc Biol 28 (1), 173-179 (2008)
   PUBMED   17975119
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   8  (bases 1 to 2568)
  AUTHORS   Shiffman,D., Ellis,S.G., Rowland,C.M., Malloy,M.J., Luke,M.M.,
            Iakoubova,O.A., Pullinger,C.R., Cassano,J., Aouizerat,B.E.,
            Fenwick,R.G., Reitz,R.E., Catanese,J.J., Leong,D.U., Zellner,C.,
            Sninsky,J.J., Topol,E.J., Devlin,J.J. and Kane,J.P.
  TITLE     Identification of four gene variants associated with myocardial
            infarction
  JOURNAL   Am J Hum Genet 77 (4), 596-605 (2005)
   PUBMED   16175505
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   9  (bases 1 to 2568)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL390860.10.
            
            On Aug 4, 2020 this sequence version replaced NM_001005487.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000642119.1/ ENSP00000493110.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-100               AL390860.10        54113-54212         c
            101-2568            AL390860.10        45285-47752         c
FEATURES             Location/Qualifiers
     source          1..2568
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q44"
     gene            1..2568
                     /gene="OR13G1"
                     /gene_synonym="OR1-37"
                     /note="olfactory receptor family 13 subfamily G member 1"
                     /db_xref="GeneID:441933"
                     /db_xref="HGNC:HGNC:14999"
                     /db_xref="MIM:611677"
     exon            1..100
                     /gene="OR13G1"
                     /gene_synonym="OR1-37"
                     /inference="alignment:Splign:2.1.0"
     exon            101..2568
                     /gene="OR13G1"
                     /gene_synonym="OR1-37"
                     /inference="alignment:Splign:2.1.0"
     CDS             339..1262
                     /gene="OR13G1"
                     /gene_synonym="OR1-37"
                     /note="olfactory receptor OR1-37"
                     /codon_start=1
                     /product="olfactory receptor 13G1"
                     /protein_id="NP_001005487.1"
                     /db_xref="CCDS:CCDS31094.1"
                     /db_xref="GeneID:441933"
                     /db_xref="HGNC:HGNC:14999"
                     /db_xref="MIM:611677"
                     /translation="MNHSVVTEFIILGLTKKPELQGIIFLFFLIVYLVAFLGNMLIII
                     AKIYNNTLHTPMYVFLLTLAVVDIICTTSIIPKMLGTMLTSENTISYAGCMSQLFLFT
                     WSLGAEMVLFTTMAYDRYVAICFPLHYSTIMNHHMCVALLSMVMAIAVTNSWVHTALI
                     MRLTFCGPNTIDHFFCEIPPLLALSCSPVRINEVMVYVADITLAIGDFILTCISYGFI
                     IVAILRIRTVEGKRKAFSTCSSHLTVVTLYYSPVIYTYIRPASSYTFERDKVVAALYT
                     LVTPTLNPMVYSFQNREMQAGIRKVFAFLKH"
ORIGIN      
        1 tttgatagca aactggcaag agctactgta cttttagttt tttacagtga tttaatacag
       61 gtcaccattt gaacatgaca atactctgca aaaaactaca tttgagtcat caatggagga
      121 acatacatca gagaatggga ttagtctgga aaacagagta tattgcctgg aatacagaac
      181 tccatcaaat gggaattcct gctgcaaagt tgtgtccaat caagaattaa gtccctaagt
      241 acacacactc ctcatgttat ctcctaacaa cacagggatt ctttccattt tcagttgttt
      301 attctgtgca attactgcca ttcaatcacc caagcaggat gaatcacagc gttgtaactg
      361 agttcattat tctgggcctc accaaaaagc ctgaactcca gggaattatc ttcctctttt
      421 ttctcattgt ctatcttgtg gcttttctcg gcaacatgct catcatcatt gccaaaatct
      481 ataacaacac cttgcatacg cccatgtatg ttttccttct gacactggct gttgtggaca
      541 tcatctgcac aacaagcatc ataccgaaga tgctggggac catgctaaca tcagaaaata
      601 ccatttcata tgcaggctgc atgtcccagc tcttcttgtt cacatggtct ctgggagctg
      661 agatggttct cttcaccacc atggcctatg accgctatgt ggccatttgt ttccctcttc
      721 attacagtac tattatgaac caccatatgt gtgtagcctt gctcagcatg gtcatggcta
      781 ttgcagtcac caattcctgg gtgcacacag ctcttatcat gaggttgact ttctgtgggc
      841 caaacaccat tgaccacttc ttctgtgaga tacccccatt gctggctttg tcctgtagcc
      901 ctgtaagaat caatgaggtg atggtgtatg ttgctgatat taccctggcc ataggggact
      961 ttattcttac ctgcatctcc tatggtttta tcattgttgc tattctccgt atccgcacag
     1021 tagaaggcaa gaggaaggcc ttctcaacat gctcatctca tctcacagtg gtgacccttt
     1081 actattctcc tgtaatctac acctatatcc gccctgcttc cagctataca tttgaaagag
     1141 acaaggtggt agctgcactc tatactcttg tgactcccac attaaacccg atggtgtaca
     1201 gcttccagaa tagggagatg caggcaggaa ttaggaaggt gtttgcattt ctgaaacact
     1261 agtagtttca acatgcaaca tcacttctgt actccagaac catcttctag agcatctcag
     1321 attttactgg tttttcatac ttacctccac tccaattttc ccttccctct tattcctgcc
     1381 ttcttcctag cagtctcatt gtctccaaaa ttctgtactc tttatgtgaa gaatattcat
     1441 aaagcaatat gcacaatacc ctcacataaa tatatgtcat aatatatatt ccaacatttt
     1501 ccaaaaatat gtacataact tcgaatactt atatatgcat atacacaaat atttacctat
     1561 atgtgcatgt gcacatcata catgcaaata tcacaaaaca ttttgtgtat tttgtgccat
     1621 ttatttgttg gtatgtgaat gtgagctgga gagaagtagt gtgtgtgata aattttccct
     1681 tgcttaatag gctgggttca ttcacttaca gcattgtgat aatgaggtat ctactctggg
     1741 gttgaacctc attacgttat ttagatttca ttggagaaaa atcgtgctct actgaataaa
     1801 attattgggc aaactctaaa gtctccatgt gttcaggaaa aagtgacaga atattactcc
     1861 agtcctttta aaccagtgag tacacttatg cctcatgcaa cattagtctg acattaggca
     1921 ggcagtcaat agtgtgtatg gcggttcaat gggtccatca atgaaacagg caccttcagt
     1981 catcttgttc tgcccttcaa tattgttttc cctaggatca tgaatggctt ttgtattact
     2041 aggcgtctca tccataaccc aagtagaatg aaggctaagg acagagattt catgaggcaa
     2101 atgaagcact gcctattatt tttataagga taacccagta agtataagct acatctcatt
     2161 ggctatagct atattattac accatttcaa gttgtaagta ccaattggaa gagtatattc
     2221 taaaattagg cacttggcac ccctgaaaaa atttggatgt aacatagatg ggatgagaaa
     2281 tgggtgtcta tactatggca gttgctatga gtatctacta gcaaatgtat cataaatgca
     2341 gatttgaagt cacaaactaa atcatgaaat aaagttaggt tgagagagtg agaatgccaa
     2401 aactgaggct acataataaa aatatacaat atacaacaca tcttataaca agttggaaga
     2461 aatatatcat ttgctgtgat tagtaaagca tatttttaca atatatttcc acaattatga
     2521 aaacatgttg gaattttgtc ttacaaatac atctggagca gttgtgtc
//
