LOCUS       NM_001004297            2082 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 13 subfamily A member 1
            (OR13A1), mRNA.
ACCESSION   NM_001004297 XM_166707
VERSION     NM_001004297.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2082)
  AUTHORS   Deloukas,P., Earthrowl,M.E., Grafham,D.V., Rubenfield,M.,
            French,L., Steward,C.A., Sims,S.K., Jones,M.C., Searle,S.,
            Scott,C., Howe,K., Hunt,S.E., Andrews,T.D., Gilbert,J.G.,
            Swarbreck,D., Ashurst,J.L., Taylor,A., Battles,J., Bird,C.P.,
            Ainscough,R., Almeida,J.P., Ashwell,R.I., Ambrose,K.D.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Bates,K.,
            Beasley,H., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.C.,
            Burrill,W., Burton,J., Cahill,P., Camire,D., Carter,N.P.,
            Chapman,J.C., Clark,S.Y., Clarke,G., Clee,C.M., Clegg,S., Corby,N.,
            Coulson,A., Dhami,P., Dutta,I., Dunn,M., Faulkner,L., Frankish,A.,
            Frankland,J.A., Garner,P., Garnett,J., Gribble,S., Griffiths,C.,
            Grocock,R., Gustafson,E., Hammond,S., Harley,J.L., Hart,E.,
            Heath,P.D., Ho,T.P., Hopkins,B., Horne,J., Howden,P.J., Huckle,E.,
            Hynds,C., Johnson,C., Johnson,D., Kana,A., Kay,M., Kimberley,A.M.,
            Kershaw,J.K., Kokkinaki,M., Laird,G.K., Lawlor,S., Lee,H.M.,
            Leongamornlert,D.A., Laird,G., Lloyd,C., Lloyd,D.M., Loveland,J.,
            Lovell,J., McLaren,S., McLay,K.E., McMurray,A.,
            Mashreghi-Mohammadi,M., Matthews,L., Milne,S., Nickerson,T.,
            Nguyen,M., Overton-Larty,E., Palmer,S.A., Pearce,A.V., Peck,A.I.,
            Pelan,S., Phillimore,B., Porter,K., Rice,C.M., Rogosin,A.,
            Ross,M.T., Sarafidou,T., Sehra,H.K., Shownkeen,R., Skuce,C.D.,
            Smith,M., Standring,L., Sycamore,N., Tester,J., Thorpe,A.,
            Torcasso,W., Tracey,A., Tromans,A., Tsolas,J., Wall,M., Walsh,J.,
            Wang,H., Weinstock,K., West,A.P., Willey,D.L., Whitehead,S.L.,
            Wilming,L., Wray,P.W., Young,L., Chen,Y., Lovering,R.C.,
            Moschonas,N.K., Siebert,R., Fechtel,K., Bentley,D., Durbin,R.,
            Hubbard,T., Doucette-Stamm,L., Beck,S., Smith,D.R. and Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 10
  JOURNAL   Nature 429 (6990), 375-381 (2004)
   PUBMED   15164054
REFERENCE   2  (bases 1 to 2082)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK131555.1 and AL512324.14.
            
            On May 17, 2019 this sequence version replaced NM_001004297.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK131555.1, DB053156.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA2155751
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000553795.6/ ENSP00000451950.1
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-179               AK131555.1         1-179
            180-181             AL512324.14        134310-134311       c
            182-901             AK131555.1         182-901
            902-903             AL512324.14        130597-130598       c
            904-1896            AK131555.1         904-1896
            1897-1963           AL512324.14        129537-129603       c
            1964-2078           AK131555.1         1964-2078
            2079-2082           AL512324.14        129418-129421       c
FEATURES             Location/Qualifiers
     source          1..2082
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q11.21"
     gene            1..2082
                     /gene="OR13A1"
                     /note="olfactory receptor family 13 subfamily A member 1"
                     /db_xref="GeneID:79290"
                     /db_xref="HGNC:HGNC:14772"
     exon            1..85
                     /gene="OR13A1"
                     /inference="alignment:Splign:2.1.0"
     exon            86..155
                     /gene="OR13A1"
                     /inference="alignment:Splign:2.1.0"
     exon            156..297
                     /gene="OR13A1"
                     /inference="alignment:Splign:2.1.0"
     exon            298..2082
                     /gene="OR13A1"
                     /inference="alignment:Splign:2.1.0"
     CDS             310..1296
                     /gene="OR13A1"
                     /note="seven transmembrane helix receptor; olfactory
                     receptor OR10-3"
                     /codon_start=1
                     /product="olfactory receptor 13A1"
                     /protein_id="NP_001004297.2"
                     /db_xref="CCDS:CCDS31188.1"
                     /db_xref="GeneID:79290"
                     /db_xref="HGNC:HGNC:14772"
                     /translation="MKLWMESHLIVPETRPSPRMMSNQTLVTEFILQGFSEHPEYRVF
                     LFSCFLFLYSGALTGNVLITLAITFNPGLHAPMYFFLLNLATMDIICTSSIMPKALAS
                     LVSEESSISYGGCMAQLYFLTWAASSELLLLTVMAYDRYAAICHPLHYSSMMSKVFCS
                     GLATAVWLLCAVNTAIHTGLMLRLDFCGPNVIIHFFCEVPPLLLLSCSSTYVNGVMIV
                     LADAFYGIVNFLMTIASYGFIVSSILKVKTAWGRQKAFSTCSSHLTVVCMYYTAVFYA
                     YISPVSGYSAGKSKLAGLLYTVLSPTLNPLIYTLRNKEVKAALRKLFPFFRN"
     regulatory      2040..2045
                     /regulatory_class="polyA_signal_sequence"
                     /gene="OR13A1"
                     /note="hexamer: AATAAA"
     polyA_site      2082
                     /gene="OR13A1"
                     /note="major polyA site"
ORIGIN      
        1 actatattga atagaagcga agagacagag tatacttgtc ttgttcctaa tccagaagaa
       61 aagtttgaat cttttaccat tgagtaagct tgagtgccca agggtttgat aaatgtggaa
      121 aataaccgct gttcgaatat cctgttggcc tgctgaagaa atgactggct gaggctgtaa
      181 agaaatcttg tggtcattct catggaaaga ggattggagc cccgattctt tgatctcatt
      241 attgaccagt tgattgagaa gactgtcctc ctgtccccac ccaatcacaa taagtggctc
      301 tgaaatcaca tgaagctgtg gatggagagt cacctgatag tcccagaaac ccgtcccagc
      361 ccaaggatga tgagtaacca gacgttggta accgagttca tcctgcaggg cttttcggag
      421 cacccagaat accgggtgtt cttattcagc tgtttcctct tcctctactc tggggccctc
      481 acaggtaatg tcctcatcac cttggccatc acgttcaacc ctgggctcca cgctcctatg
      541 tactttttct tactcaactt ggctactatg gacattatct gcacctcttc catcatgccc
      601 aaggcgctgg ccagtctggt gtcggaagag agctccatct cctacggggg ctgcatggcc
      661 cagctctatt tcctcacgtg ggctgcatcc tcagagctgc tgctcctcac ggtcatggcc
      721 tatgaccggt acgcagccat ctgccacccg ctgcattaca gcagcatgat gagcaaggtg
      781 ttctgcagcg ggctggccac agccgtgtgg ctgctctgcg ccgtcaacac ggccatccac
      841 acggggctga tgctgcgctt ggatttctgt ggccccaatg tcattatcca tttcttctgc
      901 gaggtccctc ccctgctgct tctctcctgc agctccacct acgtcaacgg tgtcatgatt
      961 gtcctggcgg atgctttcta cggcatagtg aacttcctga tgaccatcgc gtcctatggc
     1021 ttcatcgtct ccagcatcct gaaggtgaag actgcctggg ggaggcagaa agccttctcc
     1081 acctgctctt cccacctcac cgtggtgtgc atgtattaca ccgctgtctt ctacgcctac
     1141 ataagcccgg tctctggcta cagcgcaggg aagagcaagt tggctggcct gctgtacact
     1201 gtgctgagtc ctaccctcaa ccccctcatc tatactttga gaaacaagga ggtcaaagca
     1261 gccctcagga agcttttccc tttcttcaga aattaacttg tgtcttctga agtttttgtc
     1321 cttggagact gcagttttag tggagtctga tgagcaagtt tctggactgg gaggtaaata
     1381 gacttgtttt ttctaaccca gcagaacctg tgcatggatg agctgggagt gctggttccc
     1441 tgagacttgg tgatgggggg attgcggtag gtgtgaccca ccagcctctg agacaccaga
     1501 tctcttggtc tgactccaag gtggtgtcag tgctgagttg gcagagaaac acagggccta
     1561 ggaggagaaa agtgttcctt gtgttttcaa ctcatagcca catcaaacat tttccttttg
     1621 tatgtacaac actcagggtg taaattctaa aatcacacct agaattcagc tgtgtgggtc
     1681 taaaaagtta ggcagaattg tggaccccac agcccctgaa gggttgtcag actgaagctt
     1741 tgttttaagg tgaccactgg cctctaggaa accttctacc cccattatct tacctcaact
     1801 gtttcctctg gagccacttg gacttcaaaa atagtttgat tttaatgcaa actgttgttt
     1861 ctgcttttgt cttttcttct tactaacact tcagattctg agtatctgac ctacctaatt
     1921 ggcctggagc gaggacagct gccatgagtc agctctaata agttaaacgg cattgtagta
     1981 aggcattgct atccttccat tgtttcagat aaaactgggt gaacgaatcc tctgtgtcta
     2041 ataaagacag gtcttgtgct tgtgctccat gctattacaa aa
//
