LOCUS       NM_001005239             948 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 11 subfamily H member 1
            (OR11H1), mRNA.
ACCESSION   NM_001005239
VERSION     NM_001005239.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 948)
  AUTHORS   Li,X., Wang,G., Wang,X., Li,W., Li,N., Liu,X., Fan,W., He,S.,
            Han,Y., Su,G., Cao,Q., Yang,P. and Hou,S.
  TITLE     OR11H1 Missense Variant Confers the Susceptibility to
            Vogt-Koyanagi-Harada Disease by Mediating Gadd45g Expression
  JOURNAL   Adv Sci (Weinh) 11 (11), e2306563 (2024)
   PUBMED   38168905
  REMARK    GeneRIF: OR11H1 Missense Variant Confers the Susceptibility to
            Vogt-Koyanagi-Harada Disease by Mediating Gadd45g Expression.
REFERENCE   2  (bases 1 to 948)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   3  (bases 1 to 948)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP000534.1.
            
            On Feb 19, 2021 this sequence version replaced NM_001005239.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000643195.1/ ENSP00000495403.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-948               AP000534.1         32582-33529         c
FEATURES             Location/Qualifiers
     source          1..948
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q11.1"
     gene            1..948
                     /gene="OR11H1"
                     /gene_synonym="OR11H12; OR22-1"
                     /note="olfactory receptor family 11 subfamily H member 1"
                     /db_xref="GeneID:81061"
                     /db_xref="HGNC:HGNC:15404"
     CDS             1..948
                     /gene="OR11H1"
                     /gene_synonym="OR11H12; OR22-1"
                     /note="olfactory receptor OR22-1; seven transmembrane
                     helix receptor"
                     /codon_start=1
                     /product="olfactory receptor 11H1"
                     /protein_id="NP_001005239.2"
                     /db_xref="CCDS:CCDS74807.2"
                     /db_xref="GeneID:81061"
                     /db_xref="HGNC:HGNC:15404"
                     /translation="MNVSEPNSSFAFVNEFILQGFSCEWTIQIFLFSLFTTTYALTIT
                     GNGAIAFVLWCDRRLHTPMYMFLGNFSFLEIWYVSSTVPKMLVNFLSEKKNISFAGCF
                     LQFYFFFSLGTSECLLLTVMAFDQYLAICRPLLYPNIMTGHLYAKLVILCWVCGFLWF
                     LIPIVLISQMPFCGPNIIDHVVCDPGPRFALDCVSAPRIQLFCYTLSSLVIFGNFLFI
                     IGSYTLVLKAMLGMPSSTGRHKAFSTCGSHLAVVSLCYSSLMVMYVSPGLGHSTGMQK
                     IETLFYAMVTPLFNPLIYSLQNKEIKAALRKVLGSSNII"
     exon            1..948
                     /gene="OR11H1"
                     /gene_synonym="OR11H12; OR22-1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgaatgtct ctgagccaaa ttccagcttt gcttttgtaa atgaatttat actccaaggt
       61 ttctcttgtg agtggacaat tcagatcttc ctcttctcac tctttactac aacatatgca
      121 ctgactataa cagggaatgg agccattgct tttgtcctgt ggtgtgaccg gcgacttcac
      181 actcccatgt acatgttcct gggaaatttc tcctttttag agatatggta tgtctcttct
      241 acagttccca agatgttggt caacttcctt tcagagaaaa aaaacatctc ctttgctgga
      301 tgttttctcc agttttattt cttcttctct ttgggtacat cagaatgctt gcttttgact
      361 gtgatggcct ttgatcagta ccttgctatc tgccgtccct tgctctatcc taatatcatg
      421 actgggcatc tctatgccaa actggtcata ctgtgctggg tttgtggatt tctgtggttc
      481 ctgatcccca ttgttctcat ctctcagatg cccttctgtg gcccaaacat tattgaccat
      541 gttgtgtgtg acccagggcc acgatttgca ttggattgtg tttctgcccc aagaatccaa
      601 ctgttttgct acactctaag ctcattagtt atttttggta acttcctctt tattattgga
      661 tcctatactc ttgtcctgaa agctatgttg ggtatgcctt caagcactgg gagacataag
      721 gccttctcta cctgtgggtc tcatttggct gtggtatcac tgtgctatag ctctcttatg
      781 gtcatgtatg tgagcccagg actcggacat tctacaggga tgcagaaaat tgaaactttg
      841 ttctatgcta tggtgacccc actcttcaat ccccttatct atagcctcca gaataaggag
      901 ataaaggcag ccctgaggaa agttctgggg agttccaaca taatctaa
//
