LOCUS       NM_001394828            2611 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 11 subfamily A member 1
            (OR11A1), transcript variant 2, mRNA.
ACCESSION   NM_001394828
VERSION     NM_001394828.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2611)
  AUTHORS   Barcellos,L.F., May,S.L., Ramsay,P.P., Quach,H.L., Lane,J.A.,
            Nititham,J., Noble,J.A., Taylor,K.E., Quach,D.L., Chung,S.A.,
            Kelly,J.A., Moser,K.L., Behrens,T.W., Seldin,M.F., Thomson,G.,
            Harley,J.B., Gaffney,P.M. and Criswell,L.A.
  TITLE     High-density SNP screening of the major histocompatibility complex
            in systemic lupus erythematosus demonstrates strong evidence for
            independent susceptibility regions
  JOURNAL   PLoS Genet 5 (10), e1000696 (2009)
   PUBMED   19851445
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   2  (bases 1 to 2611)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   3  (bases 1 to 2611)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
REFERENCE   4  (bases 1 to 2611)
  AUTHORS   Volz,A., Ehlers,A., Younger,R., Forbes,S., Trowsdale,J.,
            Schnorr,D., Beck,S. and Ziegler,A.
  TITLE     Complex transcription and splicing of odorant receptor genes
  JOURNAL   J Biol Chem 278 (22), 19691-19701 (2003)
   PUBMED   12637542
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AJ459854.1 and AL645927.3.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000377149.5/ ENSP00000366354.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-473               AJ459854.1         1-473
            474-2611            AL645927.3         34759-36896         c
FEATURES             Location/Qualifiers
     source          1..2611
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p22.1"
     gene            1..2611
                     /gene="OR11A1"
                     /gene_synonym="6M1-18; dJ994E9.6; hs6M1-18; OR11A2"
                     /note="olfactory receptor family 11 subfamily A member 1"
                     /db_xref="GeneID:26531"
                     /db_xref="HGNC:HGNC:8176"
     exon            1..85
                     /gene="OR11A1"
                     /gene_synonym="6M1-18; dJ994E9.6; hs6M1-18; OR11A2"
                     /inference="alignment:Splign:2.1.0"
     exon            86..209
                     /gene="OR11A1"
                     /gene_synonym="6M1-18; dJ994E9.6; hs6M1-18; OR11A2"
                     /inference="alignment:Splign:2.1.0"
     exon            210..334
                     /gene="OR11A1"
                     /gene_synonym="6M1-18; dJ994E9.6; hs6M1-18; OR11A2"
                     /inference="alignment:Splign:2.1.0"
     exon            335..382
                     /gene="OR11A1"
                     /gene_synonym="6M1-18; dJ994E9.6; hs6M1-18; OR11A2"
                     /inference="alignment:Splign:2.1.0"
     exon            383..2611
                     /gene="OR11A1"
                     /gene_synonym="6M1-18; dJ994E9.6; hs6M1-18; OR11A2"
                     /inference="alignment:Splign:2.1.0"
     CDS             474..1421
                     /gene="OR11A1"
                     /gene_synonym="6M1-18; dJ994E9.6; hs6M1-18; OR11A2"
                     /note="olfactory receptor, family 11, subfamily A, member
                     2; olfactory receptor OR6-30; olfactory receptor 11A2"
                     /codon_start=1
                     /product="olfactory receptor 11A1"
                     /protein_id="NP_001381757.1"
                     /db_xref="CCDS:CCDS34363.1"
                     /db_xref="GeneID:26531"
                     /db_xref="HGNC:HGNC:8176"
                     /translation="MEIVSTGNETITEFVLLGFYDIPELHFLFFIVFTAVYVFIIIGN
                     MLIIVAVVSSQRLHKPMYIFLANLSFLDILYTSAVMPKMLEGFLQEATISVAGCLLQF
                     FIFGSLATAECLLLAVMAYDRYLAICYPLHYPLLMGPRRYMGLVVTTWLSGFVVDGLV
                     VALVAQLRFCGPNHIDQFYCDFMLFVGLACSDPRVAQVTTLILSVFCLTIPFGLILTS
                     YARIVVAVLRVPAGASRRRAFSTCSSHLAVVTTFYGTLMIFYVAPSAVHSQLLSKVFS
                     LLYTVVTPLFNPVIYTMRNKEVHQALRKILCIKQTETLD"
ORIGIN      
        1 catcctagca gtgaatggaa acacacatat ggggagaaac taaggctccc tactaaaaac
       61 gtgcaacatg tgactgggac atcttgttga gctcaagcag ggagggagct gaaggtagga
      121 aattccaaca ttctgaagtc ttcagcaaat cttagcagat catctcctcc tcacagtcct
      181 gtctttagag aacagggtcg atatttcggg aatcctatag aaagactcca agcctcagaa
      241 tgagtttgga ccagataaaa taatctagag ttaaagatgg cccacatagg gagtgccaga
      301 ttcactcaca aggaaatgca gatgggatca aaggttaata aacacatatt gctttgaata
      361 gcatatgaaa accttccagc agctctaata acgttaggct tggtatagaa gatgcagaga
      421 catgctaaaa tttctccccc aattattgcc aagcagaaac ttggacgatc gacatggaaa
      481 ttgtctccac aggaaacgaa actattactg aatttgtcct ccttggcttc tatgacatcc
      541 ctgaactgca tttcttgttt tttattgtat tcactgctgt ctatgtcttc atcatcatag
      601 ggaatatgct gattattgta gcagtggtta gctcccagag gctccacaaa cccatgtata
      661 ttttcttggc gaatctgtcc ttcctggata ttctctacac ctccgcagtg atgccaaaaa
      721 tgctggaggg cttcctgcaa gaagcaacta tctctgtggc tggttgcttg ctccagttct
      781 ttatcttcgg ctctctagcc acagctgaat gcttactgct ggctgtcatg gcatatgacc
      841 gctacctggc aatttgctac ccactccact acccactcct gatggggccc agacggtaca
      901 tggggctggt ggtcacaacc tggctctctg gatttgtggt agatggactg gttgtggccc
      961 tggtggccca gctgaggttc tgtggcccca accacattga ccagttttac tgtgacttta
     1021 tgcttttcgt gggcctggct tgctcggatc ccagagtggc tcaggtgaca actctcattc
     1081 tgtctgtgtt ctgcctcact attccttttg gactgattct gacatcttat gccagaattg
     1141 tggtggcagt gctgagagtt cctgctgggg caagcaggag aagggctttc tccacatgct
     1201 cctcccacct agctgtagtg accacattct atggaacgct catgatcttt tatgttgcac
     1261 cctctgctgt ccattcccag ctcctctcca aggtcttctc cctgctctac actgtggtca
     1321 cccctctctt caatcctgtg atctatacca tgaggaacaa ggaggtgcat caggcacttc
     1381 ggaagattct ctgtatcaaa caaactgaaa cacttgattg aaggagagta atgaagatgt
     1441 tattttggac ttcggacacc tccactgggg actcttccag gatgggttgg agaggagtaa
     1501 ctttgtctta ttcgaccatt ctctttgaac tcttctgcag ttatactaaa aatgaaaatg
     1561 atagggcaac aattttttaa cttttatttt aagttcaagg gtacatgtgc aggtttgtta
     1621 cataggtaaa cttgtgtcat gggggtttac tgtacagatt atttcatcac ccaggtatta
     1681 agcctagtac tcattaatca tttttcctga tcttctccct cctcccaacc tccaccctca
     1741 agtaggattc agtgtgttgt tcccctctat gtatccatat gttttcataa tttagctccc
     1801 acttatgagt gaagacatac ggtatttgat tttctgttcc tgtgttagtt tgcgaaggat
     1861 agtagcctcc aattccatcc atgtcaaata atcaaaatta tttaaacttt gattagttct
     1921 ttattaaata tgtcataaat atttaaaaat aatacagcaa taccaaaata aacctagaaa
     1981 tattgttttt tatattattg ttgtatgaca tttaaaaatt tctttctatg tgtatttata
     2041 tttatacata caagttggat catggagttt gtaatctggt tttccactga acactgtgtc
     2101 acgaacaact ttttctatta acaagcatct atttctttat tcttctgggc ttcatcgtat
     2161 ggctaaacat gatttgttat tctattttgg gaatttttag ttgtattcta ttcttttact
     2221 gtacattgtt tacatctgga ttttcctgta ataaactttt agcacctaaa ttgcaagatc
     2281 taaggatatg tgtttttaaa aatctaaagc tgaattcctt ttcttttaaa cttcttttct
     2341 tgtagaacat ttcaaacata cataaaagag aagagcacag tgaaccccca tgtactccat
     2401 gtagccacca tccagcttca acatcaacat tttgctaatc ttattttaat tagctacagc
     2461 tccttgtttg ttagttttca tggaaaattt tagggcaaat tccagatgtt gtataactat
     2521 tatgttgtgt aagttatgta tgtacatatt ccacatatgt atttagtata atctgtgact
     2581 aataaagaca ttttaaaaaa ccatgcccac a
//
