LOCUS       NM_001004478            6323 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 10 subfamily Z member 1
            (OR10Z1), mRNA.
ACCESSION   NM_001004478 XM_060953
VERSION     NM_001004478.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6323)
  AUTHORS   van der Harst,P., Zhang,W., Mateo Leach,I., Rendon,A., Verweij,N.,
            Sehmi,J., Paul,D.S., Elling,U., Allayee,H., Li,X.,
            Radhakrishnan,A., Tan,S.T., Voss,K., Weichenberger,C.X.,
            Albers,C.A., Al-Hussani,A., Asselbergs,F.W., Ciullo,M., Danjou,F.,
            Dina,C., Esko,T., Evans,D.M., Franke,L., Gogele,M., Hartiala,J.,
            Hersch,M., Holm,H., Hottenga,J.J., Kanoni,S., Kleber,M.E.,
            Lagou,V., Langenberg,C., Lopez,L.M., Lyytikainen,L.P., Melander,O.,
            Murgia,F., Nolte,I.M., O'Reilly,P.F., Padmanabhan,S., Parsa,A.,
            Pirastu,N., Porcu,E., Portas,L., Prokopenko,I., Ried,J.S.,
            Shin,S.Y., Tang,C.S., Teumer,A., Traglia,M., Ulivi,S., Westra,H.J.,
            Yang,J., Zhao,J.H., Anni,F., Abdellaoui,A., Attwood,A., Balkau,B.,
            Bandinelli,S., Bastardot,F., Benyamin,B., Boehm,B.O., Cookson,W.O.,
            Das,D., de Bakker,P.I., de Boer,R.A., de Geus,E.J., de Moor,M.H.,
            Dimitriou,M., Domingues,F.S., Doring,A., Engstrom,G.,
            Eyjolfsson,G.I., Ferrucci,L., Fischer,K., Galanello,R.,
            Garner,S.F., Genser,B., Gibson,Q.D., Girotto,G., Gudbjartsson,D.F.,
            Harris,S.E., Hartikainen,A.L., Hastie,C.E., Hedblad,B., Illig,T.,
            Jolley,J., Kahonen,M., Kema,I.P., Kemp,J.P., Liang,L.,
            Lloyd-Jones,H., Loos,R.J., Meacham,S., Medland,S.E., Meisinger,C.,
            Memari,Y., Mihailov,E., Miller,K., Moffatt,M.F., Nauck,M.,
            Novatchkova,M., Nutile,T., Olafsson,I., Onundarson,P.T.,
            Parracciani,D., Penninx,B.W., Perseu,L., Piga,A., Pistis,G.,
            Pouta,A., Puc,U., Raitakari,O., Ring,S.M., Robino,A., Ruggiero,D.,
            Ruokonen,A., Saint-Pierre,A., Sala,C., Salumets,A., Sambrook,J.,
            Schepers,H., Schmidt,C.O., Sillje,H.H., Sladek,R., Smit,J.H.,
            Starr,J.M., Stephens,J., Sulem,P., Tanaka,T., Thorsteinsdottir,U.,
            Tragante,V., van Gilst,W.H., van Pelt,L.J., van Veldhuisen,D.J.,
            Volker,U., Whitfield,J.B., Willemsen,G., Winkelmann,B.R.,
            Wirnsberger,G., Algra,A., Cucca,F., d'Adamo,A.P., Danesh,J.,
            Deary,I.J., Dominiczak,A.F., Elliott,P., Fortina,P., Froguel,P.,
            Gasparini,P., Greinacher,A., Hazen,S.L., Jarvelin,M.R., Khaw,K.T.,
            Lehtimaki,T., Maerz,W., Martin,N.G., Metspalu,A., Mitchell,B.D.,
            Montgomery,G.W., Moore,C., Navis,G., Pirastu,M., Pramstaller,P.P.,
            Ramirez-Solis,R., Schadt,E., Scott,J., Shuldiner,A.R., Smith,G.D.,
            Smith,J.G., Snieder,H., Sorice,R., Spector,T.D., Stefansson,K.,
            Stumvoll,M., Tang,W.H., Toniolo,D., Tonjes,A., Visscher,P.M.,
            Vollenweider,P., Wareham,N.J., Wolffenbuttel,B.H., Boomsma,D.I.,
            Beckmann,J.S., Dedoussis,G.V., Deloukas,P., Ferreira,M.A.,
            Sanna,S., Uda,M., Hicks,A.A., Penninger,J.M., Gieger,C.,
            Kooner,J.S., Ouwehand,W.H., Soranzo,N. and Chambers,J.C.
  TITLE     Seventy-five genetic loci influencing the human red blood cell
  JOURNAL   Nature 492 (7429), 369-375 (2012)
   PUBMED   23222517
REFERENCE   2  (bases 1 to 6323)
  AUTHORS   Shimada,M., Miyagawa,T., Kawashima,M., Tanaka,S., Honda,Y.,
            Honda,M. and Tokunaga,K.
  TITLE     An approach based on a genome-wide association study reveals
            candidate loci for narcolepsy
  JOURNAL   Hum Genet 128 (4), 433-441 (2010)
   PUBMED   20677014
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   3  (bases 1 to 6323)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL353894.14.
            
            On Jul 30, 2020 this sequence version replaced NM_001004478.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641002.1/ ENSP00000493003.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-134               AL353894.14        21624-21757
            135-6323            AL353894.14        22682-28870
FEATURES             Location/Qualifiers
     source          1..6323
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q23.1"
     gene            1..6323
                     /gene="OR10Z1"
                     /gene_synonym="OR1-15"
                     /note="olfactory receptor family 10 subfamily Z member 1"
                     /db_xref="GeneID:128368"
                     /db_xref="HGNC:HGNC:14996"
     exon            1..134
                     /gene="OR10Z1"
                     /gene_synonym="OR1-15"
                     /inference="alignment:Splign:2.1.0"
     exon            135..6323
                     /gene="OR10Z1"
                     /gene_synonym="OR1-15"
                     /inference="alignment:Splign:2.1.0"
     CDS             248..1189
                     /gene="OR10Z1"
                     /gene_synonym="OR1-15"
                     /note="olfactory receptor OR1-15"
                     /codon_start=1
                     /product="olfactory receptor 10Z1"
                     /protein_id="NP_001004478.1"
                     /db_xref="CCDS:CCDS30901.1"
                     /db_xref="GeneID:128368"
                     /db_xref="HGNC:HGNC:14996"
                     /translation="MGQTNVTSWRDFVFLGFSSSGELQLLLFALFLSLYLVTLTSNVF
                     IIIAIRLDSHLHTPMYLFLSFLSFSETCYTLGIIPRMLSGLAGGDQAISYVGCAAQMF
                     FSASWACTNCFLLAAMGFDRYVAICAPLHYASHMNPTLCAQLVITSFLTGYLFGLGMT
                     LVIFHLSFCSSHEIQHFFCDTPPVLSLACGDTGPSELRIFILSLLVLLVSFFFITISY
                     AYILAAILRIPSAEGQKKAFSTCASHLTVVIIHYGCASFVYLRPKASYSLERDQLIAM
                     TYTVVTPLLNPIVYSLRNRAIQTALRNAFRGRLLGKG"
ORIGIN      
        1 agagtaggag atttcaagat gcatctcaag tctttctcct gtggtctatc ctgctgggag
       61 gcagtctagt gcatgggagc taaaaggcag gacttgcttt gtgagcctct tcaggtcagc
      121 gtgagtctgt tcagttgcaa caggaacaag agaaaaagaa tccatatcat ccacctttta
      181 aagaagttag gcatctactg gcaaggtgga agaaatcaac aaatctatca gggatatacc
      241 tctcagaatg gggcagacca acgtaacctc ctggagggat tttgtcttcc tgggcttctc
      301 cagttctggg gagttgcagc tccttctctt tgccttgttc ctctctctgt atctagtcac
      361 tctgaccagc aatgtcttca ttatcatagc catcaggctg gatagccatc tgcacacccc
      421 catgtacctc ttcctttcct tcctatcctt ctctgagacc tgctacactt tgggcatcat
      481 ccctagaatg ctctctggcc tggctggggg ggaccaggct atctcctatg tgggctgtgc
      541 tgcccagatg ttcttttctg cctcatgggc ctgtactaac tgcttccttc tggctgccat
      601 gggctttgac agatatgtgg ccatctgtgc tccactccac tatgccagcc acatgaatcc
      661 taccctctgt gcccagctgg tcattacttc cttcctgact ggatacctct ttggactggg
      721 aatgacacta gttattttcc acctctcatt ctgcagctcc catgaaatcc agcacttttt
      781 ttgtgacacg ccacctgtgc tgagcctagc ctgtggagat acaggcccga gtgagctgag
      841 gatctttatc ctcagtcttt tggtcctctt ggtctccttc ttcttcatca ccatctccta
      901 cgcctacatc ttggcagcaa tactgaggat cccctctgct gaggggcaga agaaggcctt
      961 ctccacttgt gcctcgcacc ttacagtggt cattattcat tatggctgtg cttccttcgt
     1021 gtacctgagg cccaaagcca gctactctct tgagagagat cagcttattg ccatgaccta
     1081 tactgtagtg acccccctcc ttaatcccat tgtttatagt ctaaggaata gggctataca
     1141 gacagctctg aggaatgctt tcagagggag attgctgggt aaaggatgaa ggttacccca
     1201 ataggacact ttcttctgtg taggctgggc atagaccaag aacccaagcc aaagggccag
     1261 gtattcaagg cctcaggcca aagctgtcct acccccaatc ttctgggaaa gccttatcct
     1321 gcctcttgcc cttccccctg actgcttgga atgcagaggc ggggcttcct gctctgctca
     1381 ctgtgcacaa ctcaaaatga gcccaaaatc tgaattttaa ctttcagcct cctagatgcc
     1441 acccctagtt actgaaaccc attgagaatt aaaaatttaa ttaagataat caagaatttt
     1501 ttaattgagc tgaacaaaat gagggaagtt tggagtgttc aagttcaagg cagggctggc
     1561 tggagcccat cagggatact gtagagattt ctaaaatcat tacataatta gactatttga
     1621 cctgtaatgt tcttccaaga tttgaaacct ggggaatatc agcttgacag gttagtttaa
     1681 agctttgtta aatgaacagg tgggtcattt ttactcccac tgggtgtctt tcatcttttt
     1741 atgtttttat tttttttaat ttcaactatt atttcatata cagtggggca catgtgctta
     1801 tacattcctc attgtgctat tgacagtagc aaaaacatgg aatcatcttt ttatatagtt
     1861 gtcctcacta tctctgactc tgttactttg ccctttttgt tttgattgat tttccaagct
     1921 gggtgcactc tatttcagaa aatatattta cttcctattt ttttttataa ctgttaatgt
     1981 tccctggtag cttcagaatc ttgagtgtca aagacctttc tcatttgggt cgcttatcaa
     2041 attggatact gttcttttga atctattgca gaactatcta ttctgcctat tccactttcc
     2101 acatataatg tggttatata tagcggcgga cattattaga gaaagtgtaa tgaactcaca
     2161 agaccgtcag gcaggagttt gaatccaaac tcttcaactt actagctgtg tgactctagg
     2221 taagttattt aacatttttt tcagcttccg agtcttatct ttacaatggt tggtgactaa
     2281 acaggatcat gcatacaaag aatttagcac aacccttgga tcatagcgat cgtccaataa
     2341 attccagttg ctactattaa aatgtgtgaa ggaaaaagat attggctttt agtttaggta
     2401 gagtttactc taggtggagg atcagagaag acttcatgtc ttaaatagta tctgaacttg
     2461 ttcctaaagg atgggtgagc tttgaatgca ctgactgggg agaaagtaca ttctcagaag
     2521 agagaatgta atagccaaag gcttgatggt aagacaatat aagcctagtt taatgtgtgt
     2581 gagttattca gaggggctgg aaacaactca caaatgatgc tgagaagtta gtttgagtca
     2641 tgacttactt gttgaaataa tttgaatacc ttgcttcaga catggtcctt ttgtctatag
     2701 gagataaggc acagtaaaac gttgaacaga gagaggcatc tgggaaggga ttcaggaaga
     2761 ttaatccagc agcaaagggg atgatagatt tcagtagaga gaaaccagag gcaaggagat
     2821 cagcaagaaa cccatggata tcagcttaaa aaaaggcaaa gaggcttgaa tatggatagt
     2881 gacattcaga gactgaagga aatcacaaac atgagatttt gagaaggtag aattcacagg
     2941 atttggcagt gagatagaag tggggcatgg cttgagagac aaggaaagac cttaggccga
     3001 gaagatattt ttcagacaga aatccatatt ttttcatgct ttcaggaaag aaatacatcc
     3061 tctaattgga atttgatgaa aacaatttga gaggaaggaa gctagagctc agagaagaga
     3121 acaggatgaa gacaagtaga tgagttagtc agatagccaa aagggcctca tcaggggaga
     3181 aaggccatct actctgaagt tctcaatatt ggaagaagta atgcctcatt gcactgaggc
     3241 catgtgagca aattcatttc accagttcat tcagtctgcc cagcataaca ttgactaaat
     3301 gcacagtgac gaatggttag taaggatgtt tcaagtattg ctaagtaata cttagaggtc
     3361 taacttccac atgtagtagt cttaagtatg gaagggtata aaatcacttg gagggatttt
     3421 tccaaatagg tgtttttgga atctatctaa tttgtttcta ccttgaaaca attgatttgg
     3481 gatagggaca acataatagt cttcaaaatc tcgtttggtg attcaaattt cctctcttga
     3541 ttaagtatgt gactacgcgc ttagaaaggg caaactcttc ttccaggtac acacatttga
     3601 cccactaaat gactaataat ttgatttagg ccttgaaaat ttttggcagg gttagcattg
     3661 ggggaatgga atcacatcca cctttgcttg tgattatttt cagcacaaat agttttagac
     3721 tatccatatg tggtaagtgt gatattaaac aatgctaatt ttcgatggcc tatatctttt
     3781 ctaactgtac tatttttggt aacttataat caggcaattt agacatttgt gaacattaat
     3841 tttgaaaata ctttctgctt gttatattcc atagtatttg actatttaag aaaagaatca
     3901 ctaaaatacc tgtatgttgt tagtatcaat gataactttt tagctttaac caactttttg
     3961 tttaaaaaag gctcctatga caggatttgt cctgcacaga ttcatttcta tgcagaggaa
     4021 gggactgaga cttaagatgg taatcaagtg gcaacatgaa tggattggta agtggggact
     4081 atttgtgcag aacgctagca gttttataca cagcaattaa gatatctaag aattctcacc
     4141 agcaaatgac accattacct tttatagatc aaatcagaat gtcggcatat aaacctgttc
     4201 agaataaacc tggcctgaaa atttttgaag atagcatcac ctcttctttt tttaaaatta
     4261 attcttaatt ttataaataa ttctattaac tgttacttta acaggatatt gaagtattat
     4321 ttttattaca ttaaaactta agagaaaata cgggagcttg gaggacaaga gaaagccctg
     4381 ctatgctgga attttgtctt tctgagagta ataacatcta caataatttt gaagtatgga
     4441 aaaaaaacaa gaagaaaaca ggtgttatgc tgatctgtgt gttgtttcat tgtacaaact
     4501 aaaatattca tgttccccag aaaatcaaat atctttattt tcaaatttaa atttaaacac
     4561 attccaaagt ttaaaaaaat tgtttgaaaa ttgccttgga ttttatttat ctactatacc
     4621 atggcccttc tttacagtaa aattagctgc ccactcttat atgagtacag ttcccagaaa
     4681 tatagaagct caacatttta cttaactttg ccccaaaaaa tatttttaaa aagaattact
     4741 ttattctata atcggaataa agcaaaatga taaagacgtg caaaacagaa caaataaaaa
     4801 tagaaacttt gacacccctc agcagtgact agttgcatac aaaatagctt ccactcctcc
     4861 aactctatta acctttctat ctcccaccct tgagattttt taagatccta caataaatgt
     4921 aatatgcaca caaacacaag cacacacaca cacacacaca cacacacaca cacacgaggc
     4981 catctttatc ttccacattt gcctgtactc tttgcccccc agtaaatttc ccacgacact
     5041 aagattttct acgatccacg aggagctgct tattagttgc caaagtagga attggtgaag
     5101 ccaacgtagt catagccaga gagatggctt cgaccccgtg ggtccatata ttgctgcata
     5161 tgtgtggcac agaatgacac ttgctctggg gtaagggcct gaaaagtata aaaagagaaa
     5221 aatacagtta tagggattca aaatagctgg ttccttgggg cttcccatat tacgccataa
     5281 atgcaggaga tggagagtct ctggaagacg caagccctat ttctattaca cacaattttt
     5341 atctcataaa tttataattt ctaatgagta acttaacttt taatctcagc cctttcttga
     5401 aaaagagagc ttactcactt tgattattct gtaaatctca ttccctaaag ttgttttatt
     5461 aaatagaagg aattatatgc ctaacaacat ttgttgacca cttgatctat ttcatcttcc
     5521 tggctgcttt gagatgtggg gactagcatg ttttatgagt aaggtaaaat actcaagaag
     5581 gtagaataac tcaccagtgg ttacactgcc agaaagtggt agagctggga cttgaaccta
     5641 tgatcctctt atgccaaaga gttcctctat tcactgtgct gtttgattac caagtggatc
     5701 cctaaagact ccaataagtt agcgtgtggg tgggtggctc cagatagtgt ctggaagacc
     5761 acatcatttt ctttttgtaa cagctttgtc gaggtatgat tgataaagaa ttgcaccttt
     5821 aatgtgtaca gtttgatgag tttagacaat tggatgagtt tgtgcaaaac gataccatca
     5881 tgtatgtgac cctttgtaat ctggtttctg cttaattgtt ttccctttca ctttctgtta
     5941 ctatcttctt accttatgct ttaggtatta ggaaaatctg ttttctcaag ttcctttgca
     6001 cacacacttg cctttgcctg aaacacttag gctttccttt gatgacttga tgagttcctg
     6061 cacgtccttc aacactcacc ctgtgttaat catagatgat actttccctg atgcaagtat
     6121 tttaaggaga ggaatgaaga aagctcttgg aatcagagag aagagagatt acttctggtt
     6181 gtaataaaat tccccacatc tttgttccca tgacagatgt gtttgcttct gttacagtgt
     6241 ttttaacttg taaagttctg tcttccccac tacacctgaa tttagggact gtgtcttact
     6301 aaagtttgca ctcctcatgc ctg
//
