LOCUS       NM_001004473            2124 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 10 subfamily K member 1
            (OR10K1), mRNA.
ACCESSION   NM_001004473
VERSION     NM_001004473.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2124)
  AUTHORS   Shimada,M., Miyagawa,T., Kawashima,M., Tanaka,S., Honda,Y.,
            Honda,M. and Tokunaga,K.
  TITLE     An approach based on a genome-wide association study reveals
            candidate loci for narcolepsy
  JOURNAL   Hum Genet 128 (4), 433-441 (2010)
   PUBMED   20677014
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   2  (bases 1 to 2124)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL365440.13.
            
            On Jul 28, 2020 this sequence version replaced NM_001004473.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641535.1/ ENSP00000493025.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-71                AL365440.13        39596-39666
            72-2124             AL365440.13        43168-45220
FEATURES             Location/Qualifiers
     source          1..2124
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q23.1"
     gene            1..2124
                     /gene="OR10K1"
                     /gene_synonym="OR1-6"
                     /note="olfactory receptor family 10 subfamily K member 1"
                     /db_xref="GeneID:391109"
                     /db_xref="HGNC:HGNC:14693"
     exon            1..71
                     /gene="OR10K1"
                     /gene_synonym="OR1-6"
                     /inference="alignment:Splign:2.1.0"
     exon            72..2124
                     /gene="OR10K1"
                     /gene_synonym="OR1-6"
                     /inference="alignment:Splign:2.1.0"
     CDS             228..1169
                     /gene="OR10K1"
                     /gene_synonym="OR1-6"
                     /note="olfactory receptor OR1-6"
                     /codon_start=1
                     /product="olfactory receptor 10K1"
                     /protein_id="NP_001004473.1"
                     /db_xref="CCDS:CCDS30897.1"
                     /db_xref="GeneID:391109"
                     /db_xref="HGNC:HGNC:14693"
                     /translation="MEQVNKTVVREFVVLGFSSLARLQQLLFVIFLLLYLFTLGTNAI
                     IISTIVLDRALHTPMYFFLAILSCSEICYTFVIVPKMLVDLLSQKKTISFLGCAIQMF
                     SFLFFGSSHSFLLAAMGYDRYMAICNPLRYSVLMGHGVCMGLMAAACACGFTVSLVTT
                     SLVFHLPFHSSNQLHHFFCDISPVLKLASQHSGFSQLVIFMLGVFALVIPLLLILVSY
                     IRIISAILKIPSSVGRYKTFSTCASHLIVVTVHYSCASFIYLRPKTNYTSSQDTLISV
                     SYTILTPLFNPMIYSLRNKEFKSALRRTIGQTFYPLS"
ORIGIN      
        1 cttgaatgat gggtagtgtt tgagaaagcc tctttctgtg cctcccatgg agatcagtga
       61 tggcatttct gcaggcattt taatggggga atgaagaatt ccatcaaata tctggaaatg
      121 cctgccacct gcaaactttg tgtgaaattt cccgtacatt tccactctcc tttctggatc
      181 ctggtttcta cctctgtccc tgactctcct ttatagaagt gctctccatg gagcaagtca
      241 ataagactgt ggtgagagag ttcgtcgtcc tcggcttctc atccctggcc aggctgcagc
      301 agctgctctt tgttatcttc ctgctcctct acctgttcac tctgggcacc aatgcaatca
      361 tcatttccac cattgtgctg gacagagccc ttcatactcc catgtacttc ttccttgcca
      421 tcctttcttg ctctgagatt tgctatacct ttgtcattgt acccaagatg ctggttgacc
      481 tgctgtccca gaagaagacc atttctttcc tgggctgtgc catccaaatg ttttccttcc
      541 tcttctttgg ctcctctcac tccttcctgc tggcagccat gggctatgat cgctatatgg
      601 ccatctgtaa cccactgcgc tactcagtgc tcatgggaca tggggtgtgt atgggactaa
      661 tggctgctgc ctgtgcctgt ggcttcactg tctccctggt caccacctcc ctagtatttc
      721 atctgccctt ccactcctcc aaccagctcc atcacttctt ctgtgacatc tcccctgtcc
      781 ttaaactggc atctcagcac tccggcttca gtcagctggt catattcatg cttggtgtat
      841 ttgccttggt cattcctctg ctacttatcc tagtctccta catccgcatc atctctgcca
      901 ttctaaaaat cccttcctcc gttggaagat acaagacctt ctccacctgt gcctcccatc
      961 tcattgtggt aactgttcac tacagttgtg cctctttcat ctacttaagg cccaagacta
     1021 attacacttc aagccaagac accctaatat ctgtgtcata caccatcctt accccattgt
     1081 tcaatccaat gatttatagt ctgagaaata aggaattcaa atcagcccta cgaagaacaa
     1141 tcggccaaac tttctatcct cttagttaaa gagctatttt ttaaactact aatgcctagt
     1201 acatgccagg cagaacgtgt gttttataca ttttttttca tttaattgtc cagctccact
     1261 gtaacataag aacattttac atatgagaag aatgaggctc acagaagtta agacagtctg
     1321 gctttctact ctccatgata ctttaacaag actaatcaga tatgggaaca gagcacacag
     1381 ttccataaca aatttaatta tattttactg ctttaaatat tgctaattta aaaactaata
     1441 tgagagcaaa gatgcatcta aactgatgag agctgtgtct tgaagtagag agcttggata
     1501 catcaggaaa gaaaagatgt atccaaaaaa aaaaaaagaa agaaaaaaga aaaaaaaaag
     1561 gaaaacagca ggaaatccat ctatccgtac ttttcttttc ctaaagacaa cagaaaactt
     1621 tggtcccaca cattctgcta caaatcttgg tggtcctttt tgtccccaat tcatttcctt
     1681 aacctacata ttgaaatatc ttggccttta cttggggttg ttttgttctt cctttgtttg
     1741 aggtggaacc actttatggt tctcttcctg atgcacatgt atgtccttca catactagtg
     1801 tgtcttagcc cccacatttg ttcctgagac accatactaa tttgctctct tcaaggaagc
     1861 tactagcatt gcctacttgc tgaaatatct caagtaattc caagcaaagg gcttgagtta
     1921 atattaatag aaggctagat tcctagaatg accagaaaac tcatggaaaa ccctccagtg
     1981 actccctttg ccctacaaga taatgccaag ggtccttcat tgtcatgaat ctatcatcta
     2041 gtttccacct acctcttcag tattatcatt tctaattttg ttattctcca ttttctatat
     2101 gccttttgta cactctgaag ctaa
//
