LOCUS       NM_001004469             930 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 10 subfamily J member 5
            (OR10J5), mRNA.
ACCESSION   NM_001004469 XM_060458
VERSION     NM_001004469.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 930)
  AUTHORS   Tong,T., Ryu,S.E., Min,Y., de March,C.A., Bushdid,C.,
            Golebiowski,J., Moon,C. and Park,T.
  TITLE     Olfactory receptor 10J5 responding to alpha-cedrene regulates
            hepatic steatosis via the cAMP-PKA pathway
  JOURNAL   Sci Rep 7 (1), 9471 (2017)
   PUBMED   28842679
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 930)
  AUTHORS   Kim,S.H., Yoon,Y.C., Lee,A.S., Kang,N., Koo,J., Rhyu,M.R. and
            Park,J.H.
  TITLE     Expression of human olfactory receptor 10J5 in heart aorta,
            coronary artery, and endothelial cells and its functional role in
            angiogenesis
  JOURNAL   Biochem Biophys Res Commun 460 (2), 404-408 (2015)
   PUBMED   25791473
  REMARK    GeneRIF: data demonstrate the physiological role of OR10J5 in
            angiogenesis and represent roles of ORs in HUVEC cells
REFERENCE   3  (bases 1 to 930)
  AUTHORS   Reiner,A.P., Beleza,S., Franceschini,N., Auer,P.L., Robinson,J.G.,
            Kooperberg,C., Peters,U. and Tang,H.
  TITLE     Genome-wide association and population genetic analysis of
            C-reactive protein in African American and Hispanic American women
  JOURNAL   Am J Hum Genet 91 (3), 502-512 (2012)
   PUBMED   22939635
REFERENCE   4  (bases 1 to 930)
  AUTHORS   Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
            Gibbs,R.A. and Butte,N.F.
  TITLE     Novel genetic loci identified for the pathophysiology of childhood
            obesity in the Hispanic population
  JOURNAL   PLoS One 7 (12), e51954 (2012)
   PUBMED   23251661
REFERENCE   5  (bases 1 to 930)
  AUTHORS   Yang,Q., Kathiresan,S., Lin,J.P., Tofler,G.H. and O'Donnell,C.J.
  TITLE     Genome-wide association and linkage analyses of hemostatic factors
            and hematological phenotypes in the Framingham Heart Study
  JOURNAL   BMC Med Genet 8 Suppl 1 (Suppl 1), S12 (2007)
   PUBMED   17903294
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 930)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   7  (bases 1 to 930)
  AUTHORS   Gilad,Y., Bustamante,C.D., Lancet,D. and Paabo,S.
  TITLE     Natural selection on the olfactory receptor gene family in humans
            and chimpanzees
  JOURNAL   Am J Hum Genet 73 (3), 489-501 (2003)
   PUBMED   12908129
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL606752.11.
            
            On Sep 18, 2004 this sequence version replaced XM_060458.4.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC137026.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000334857.3/ ENSP00000334441.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-930               AL606752.11        38458-39387         c
FEATURES             Location/Qualifiers
     source          1..930
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q23.2"
     gene            1..930
                     /gene="OR10J5"
                     /gene_synonym="MOR23; OLFR16; OR1-28"
                     /note="olfactory receptor family 10 subfamily J member 5"
                     /db_xref="GeneID:127385"
                     /db_xref="HGNC:HGNC:14993"
                     /db_xref="MIM:619546"
     CDS             1..930
                     /gene="OR10J5"
                     /gene_synonym="MOR23; OLFR16; OR1-28"
                     /note="olfactory receptor OR1-28"
                     /codon_start=1
                     /product="olfactory receptor 10J5"
                     /protein_id="NP_001004469.1"
                     /db_xref="CCDS:CCDS30910.1"
                     /db_xref="GeneID:127385"
                     /db_xref="HGNC:HGNC:14993"
                     /db_xref="MIM:619546"
                     /translation="MKRKNFTEVSEFIFLGFSSFGKHQITLFVVFLTVYILTLVANII
                     IVTIICIDHHLHTPMYFFLSMLASSETVYTLVIVPRMLLSLIFHNQPISLAGCATQMF
                     FFVILATNNCFLLTAMGYDRYVAICRPLRYTVIMSKGLCAQLVCGSFGIGLTMAVLHV
                     TAMFNLPFCGTVVDHFFCDIYPVMKLSCIDTTINEIINYGVSSFVIFVPIGLIFISYV
                     LVISSILQIASAEGRKKTFATCVSHLTVVIVHCGCASIAYLKPKSESSIEKDLVLSVT
                     YTIITPLLNPVVYSLRNKEVKDALCRVVGRNIS"
     exon            1..930
                     /gene="OR10J5"
                     /gene_synonym="MOR23; OLFR16; OR1-28"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgaagagaa agaacttcac agaagtgtca gaattcattt tcttgggatt ttctagcttt
       61 ggaaagcatc agataaccct ctttgtggtt ttcctaactg tctacatttt aactctggtt
      121 gctaacatca tcattgtgac tatcatctgc attgaccatc atctccacac tcccatgtat
      181 ttcttcctaa gcatgctggc tagttcagag acggtgtaca cactggtcat tgtgccacga
      241 atgcttttga gcctcatttt tcataaccaa cctatctcct tggcaggctg tgctacacaa
      301 atgttctttt ttgttatctt ggccactaat aattgcttcc tgcttactgc aatggggtat
      361 gaccgctatg tggccatctg cagacccctg agatacactg tcatcatgag caagggacta
      421 tgtgcccagc tggtgtgtgg gtcctttggc attggtctga ctatggcagt tctccatgtg
      481 acagccatgt tcaatttgcc gttctgtggc acagtggtag accacttctt ttgtgacatt
      541 tacccagtca tgaaactttc ttgcattgat accactatca atgagataat aaattatggt
      601 gtaagttcat ttgtgatttt tgtgcccata ggcctgatat ttatctccta tgtccttgtc
      661 atctcttcca tccttcaaat tgcctcagct gagggccgga agaagacctt tgccacctgt
      721 gtctcccacc tcactgtggt tattgtccac tgtggctgtg cctccattgc ctacctcaag
      781 ccgaagtcag aaagttcaat agaaaaagac cttgttctct cagtgacgta caccatcatc
      841 actcccttgc tgaaccctgt tgtttacagt ctgagaaaca aggaggtaaa ggatgcccta
      901 tgcagagttg tgggcagaaa tatttcttaa
//
