LOCUS       NM_012351               1246 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 10 subfamily J member 1
            (OR10J1), transcript variant 3, mRNA.
ACCESSION   NM_012351
VERSION     NM_012351.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Reiner,A.P., Beleza,S., Franceschini,N., Auer,P.L., Robinson,J.G.,
            Kooperberg,C., Peters,U. and Tang,H.
  TITLE     Genome-wide association and population genetic analysis of
            C-reactive protein in African American and Hispanic American women
  JOURNAL   Am J Hum Genet 91 (3), 502-512 (2012)
   PUBMED   22939635
REFERENCE   2  (bases 1 to 1246)
  AUTHORS   Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
            Gibbs,R.A. and Butte,N.F.
  TITLE     Novel genetic loci identified for the pathophysiology of childhood
            obesity in the Hispanic population
  JOURNAL   PLoS One 7 (12), e51954 (2012)
   PUBMED   23251661
REFERENCE   3  (bases 1 to 1246)
  AUTHORS   Bozaoglu,K., Curran,J.E., Stocker,C.J., Zaibi,M.S., Segal,D.,
            Konstantopoulos,N., Morrison,S., Carless,M., Dyer,T.D., Cole,S.A.,
            Goring,H.H., Moses,E.K., Walder,K., Cawthorne,M.A., Blangero,J. and
            Jowett,J.B.
  TITLE     Chemerin, a novel adipokine in the regulation of angiogenesis
  JOURNAL   J Clin Endocrinol Metab 95 (5), 2476-2485 (2010)
   PUBMED   20237162
REFERENCE   4  (bases 1 to 1246)
  AUTHORS   Yang,Q., Kathiresan,S., Lin,J.P., Tofler,G.H. and O'Donnell,C.J.
  TITLE     Genome-wide association and linkage analyses of hemostatic factors
            and hematological phenotypes in the Framingham Heart Study
  JOURNAL   BMC Med Genet 8 Suppl 1 (Suppl 1), S12 (2007)
   PUBMED   17903294
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1246)
  AUTHORS   Benjamin,E.J., Dupuis,J., Larson,M.G., Lunetta,K.L., Booth,S.L.,
            Govindaraju,D.R., Kathiresan,S., Keaney,J.F. Jr., Keyes,M.J.,
            Lin,J.P., Meigs,J.B., Robins,S.J., Rong,J., Schnabel,R., Vita,J.A.,
            Wang,T.J., Wilson,P.W., Wolf,P.A. and Vasan,R.S.
  TITLE     Genome-wide association with select biomarker traits in the
            Framingham Heart Study
  JOURNAL   BMC Med Genet 8 Suppl 1 (Suppl 1), S11 (2007)
   PUBMED   17903293
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1246)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   7  (bases 1 to 1246)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
REFERENCE   8  (bases 1 to 1246)
  AUTHORS   Parmentier,M., Libert,F., Schurmans,S., Schiffmann,S., Lefort,A.,
            Eggerickx,D., Ledent,C., Mollereau,C., Gerard,C., Perret,J. et al.
  TITLE     Expression of members of the putative olfactory receptor gene
            family in mammalian germ cells
  JOURNAL   Nature 355 (6359), 453-455 (1992)
   PUBMED   1370859
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL663023.10 and BC069150.1.
            
            On Nov 7, 2018 this sequence version replaced NM_012351.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC112292.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000423932.6/
                                                ENSP00000399078.4
            RefSeq Select criteria           :: based on manual assertion,
                                                conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-49                AL663023.10        27209-27257
            50-222              BC069150.1         13-185
            223-346             AL663023.10        27431-27554
            347-1000            BC069150.1         310-963
            1001-1246           AL663023.10        28209-28454
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q23.2"
     gene            1..1246
                     /gene="OR10J1"
                     /gene_synonym="HGMP07J; HSHGMP07J"
                     /note="olfactory receptor family 10 subfamily J member 1"
                     /db_xref="GeneID:26476"
                     /db_xref="HGNC:HGNC:8175"
     exon            1..1246
                     /gene="OR10J1"
                     /gene_synonym="HGMP07J; HSHGMP07J"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..1000
                     /gene="OR10J1"
                     /gene_synonym="HGMP07J; HSHGMP07J"
                     /note="olfactory receptor OR1-26; olfactory receptor-like
                     protein HGMP07J"
                     /codon_start=1
                     /product="olfactory receptor 10J1"
                     /protein_id="NP_036483.3"
                     /db_xref="CCDS:CCDS86023.1"
                     /db_xref="GeneID:26476"
                     /db_xref="HGNC:HGNC:8175"
                     /translation="MKRENFTLITDFVFQGFSSFHEQQITLFGVFLALYILTLAGNII
                     IVTIIRMDLHLHTPMYFFLSMLSTSETVYTLVILPRMLSSLVGMSQPISLAGCATQMF
                     FFVTFGITNCFLLTAMGYDRYVAICNPLRYMVIMNKRLRIQLVLGACSIGLIVAITQV
                     TSVFRLPFCARKVPHFFCDIRPVMKLSCIDTTVNEILTLIISVLVLVVPMGLVFISYV
                     LIISTILKIASVEGRKKAFATCASHLTVVIVHYSCASIAYLKPKSENTREHDQLISVT
                     YTVITPLLNPVVYTLRNKEVKDALCRAVGGKFS"
     regulatory      1228..1233
                     /regulatory_class="polyA_signal_sequence"
                     /gene="OR10J1"
                     /gene_synonym="HGMP07J; HSHGMP07J"
                     /note="hexamer: AATAAA"
     polyA_site      1246
                     /gene="OR10J1"
                     /gene_synonym="HGMP07J; HSHGMP07J"
                     /note="major polyA site"
ORIGIN      
        1 tgtgcttcta ctgctttact gggactatgt gacttttatg cttttatgtt tcagatttgg
       61 gaaccaatcc atgaaaagag agaactttac tctcatcact gactttgttt tccaaggttt
      121 ctctagcttc catgagcagc agatcaccct ttttggcgtg ttccttgcac tatacatctt
      181 aaccttagca ggcaatatca tcattgtgac catcatccga atggatcttc atcttcacac
      241 acccatgtac ttcttcctga gcatgctgtc cacttcagag actgtatata cattggtcat
      301 tctcccaaga atgctctcca gcctcgtagg tatgagccag cccatatcat tggcagggtg
      361 tgccacacag atgttctttt ttgtaacctt tggcatcact aactgcttcc tgctcacagc
      421 aatgggatat gaccgctatg tggccatctg caaccccctg agatacatgg ttattatgaa
      481 caagaggctg cgtatccaac ttgtcctggg ggcctgcagc attgggctga ttgtagcaat
      541 aacgcaagtg acatctgtat tcaggttacc cttctgtgct agaaaggtgc cccacttctt
      601 ctgtgacatc cgccctgtga tgaagctctc ctgcattgac accactgtca atgaaatcct
      661 gactttgatt atcagtgtgc tggtgcttgt tgtacctatg ggtctggttt tcatttctta
      721 tgttctcatt atctctacaa tcctcaagat tgcttcagtt gagggccgga agaaggcttt
      781 tgccacctgt gcatcccacc tcactgtggt cattgtccac tacagctgtg cctccattgc
      841 ctacctcaag cccaagtcag agaacaccag agaacatgac cagctgatct cggtgaccta
      901 cactgtcatc actcccctac tgaaccctgt ggtatacacc ctgagaaata aagaggtcaa
      961 agatgctctg tgcagggctg ttggtgggaa gttttcctga ccatgtagga agagttctcc
     1021 tgaggctgtc aacatccaca ctaggcagga atatgaggtg taaactcaca aacacttggc
     1081 tcctagagac ctgcccctta aataagaggc aaaagaggaa tagcagtttc atacaactgg
     1141 gagtctgaag ctttaaataa agttactgga tggagtgtta tccctatttt tggggataaa
     1201 tagacaaaca aggataagat atgcctaaat aaaaggccag aaagta
//
