LOCUS       NM_001004466            6376 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 10 subfamily H member 5
            (OR10H5), mRNA.
ACCESSION   NM_001004466 XM_210787
VERSION     NM_001004466.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6376)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 6376)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC011537.8.
            
            On Aug 6, 2020 this sequence version replaced NM_001004466.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000642092.2/ ENSP00000493242.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-56                AC011537.8         27206-27261
            57-6376             AC011537.8         33583-39902
FEATURES             Location/Qualifiers
     source          1..6376
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.12"
     gene            1..6376
                     /gene="OR10H5"
                     /gene_synonym="OR19-25; OR19-26"
                     /note="olfactory receptor family 10 subfamily H member 5"
                     /db_xref="GeneID:284433"
                     /db_xref="HGNC:HGNC:15389"
     exon            1..56
                     /gene="OR10H5"
                     /gene_synonym="OR19-25; OR19-26"
                     /inference="alignment:Splign:2.1.0"
     exon            57..6376
                     /gene="OR10H5"
                     /gene_synonym="OR19-25; OR19-26"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..1015
                     /gene="OR10H5"
                     /gene_synonym="OR19-25; OR19-26"
                     /note="olfactory receptor OR19-26; olfactory receptor
                     OR19-25"
                     /codon_start=1
                     /product="olfactory receptor 10H5"
                     /protein_id="NP_001004466.1"
                     /db_xref="CCDS:CCDS32940.1"
                     /db_xref="GeneID:284433"
                     /db_xref="HGNC:HGNC:15389"
                     /translation="MQGLNHTSVSEFILVGFSAFPHLQLMLFLLFLLMYLFTLLGNLL
                     IMATVWSERSLHMPMYLFLCALSITEILYTVAIIPRMLADLLSTQRSIAFLACASQMF
                     FSFSFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSLRGCTCRVGCSWAGGLVMGMVVT
                     SAIFHLAFCGHKEIHHFFCHVPPLLKLACGDDVLVVAKGVGLVCITALLGCFLLILLS
                     YAFIVAAILKIPSAEGRNKAFSTCASHLTVVVVHYGFASVIYLKPKGPQSPEGDTLMG
                     ITYTVLTPFLSPIIFSLRNKELKVAMKKTCFTKLFPQNC"
     regulatory      6356..6361
                     /regulatory_class="polyA_signal_sequence"
                     /gene="OR10H5"
                     /gene_synonym="OR19-25; OR19-26"
                     /note="hexamer: AATAAA"
     polyA_site      6376
                     /gene="OR10H5"
                     /gene_synonym="OR19-25; OR19-26"
                     /note="major polyA site"
ORIGIN      
        1 tgcccagggc cattacaggc ctggctgcaa ggcgtcccta aaggtctctg atgaaggggt
       61 ggccgccatg caggggctaa accacacctc cgtgtctgaa ttcatcctcg ttggcttctc
      121 tgccttcccc cacctccagc tgatgctctt cctgctgttc ctgctgatgt acctgttcac
      181 gctgctgggc aacctgctca tcatggccac tgtctggagc gagcgcagcc tccacatgcc
      241 catgtacctc ttcctgtgtg ccctctccat caccgagatc ctctacaccg tggccatcat
      301 cccgcgcatg ctggccgacc tgctgtccac ccagcgctcc atcgccttcc tggcctgtgc
      361 cagtcagatg ttcttctcct tcagcttcgg cttcacccac tccttcctgc tcactgtcat
      421 gggctacgac cgctacgtgg ccatctgcca ccccctgcgt tacaacgtgc tcatgagcct
      481 gcggggctgc acctgccggg tgggctgctc ctgggctggt ggcttggtca tggggatggt
      541 ggtgacctcg gccattttcc acctcgcctt ctgtggacac aaggagatcc accatttctt
      601 ctgccacgtg ccacctctgt tgaagttggc ctgtggagat gatgtgctgg tggtggccaa
      661 aggcgtgggc ttggtgtgta tcacggccct gctgggctgt tttctcctca tcctcctctc
      721 ctatgccttc atcgtggccg ccatcttgaa gatcccttct gctgaaggtc ggaacaaggc
      781 cttctccacc tgtgcctctc acctcactgt ggtggtcgtg cactatggct ttgcctccgt
      841 catttacctg aagcccaaag gtccccagtc tccggaagga gacaccttga tgggcatcac
      901 ctacacggtc ctcacaccct tcctcagccc catcatcttc agcctcagga acaaggagct
      961 gaaggtcgcc atgaagaaga cttgcttcac caaactcttt ccacagaact gctgaaatgg
     1021 ctgactttct ctcaagagat gtagcgaatg ggaacacttt agtcttcctc ctttatttct
     1081 tttcctttcc tccctccctc ctttcctccc tccctccctt ccttccttct ttccttcctc
     1141 cctccctcct ttcctccctc cttctctgac ctacagtcca ccctccctcc cccctcctcc
     1201 ttgccttcct tccatccttc ctccctccct ccctccccct tccttcttct ctgcctactt
     1261 ccctctttcc cttctctctg tctctttctg tttctatacc tctctgtctc tgtcactctc
     1321 tttctccctc cttgttcttt tgtttttgtt tttgtttttg ttttgactga gtctcgttct
     1381 gtcacccagg ttggagtgcg ttggcacaat ctcggctcac tgcaacctcc acctcctggg
     1441 ttcaagcgat tctcctgcct cagcctcccg actagctggg attacaggca cacaccacca
     1501 tgcctggcta atttttgtat ttgtagtaga gacggggttt caccatgttg gccaggctgg
     1561 tctcgaactc ctgacctcag gcattatgcc cacctcagcc tcccaaagtg ctgggatcac
     1621 aggcgtgagt caccacaccc agccctgact tttttactgt agacatccca gtggtttctt
     1681 attggggttt tgatttgcat ttccccaatg actaatgaca ggctttaggt gcttaacaca
     1741 tgtgagttat tttacttcac agggaagata ggattactaa ctccattttg tttgttcgtt
     1801 agttggttgg ttttatacac ggtcttgctc tgttgcccag gctggagtgc agtagtccaa
     1861 tcatggctaa gtgcagcgtc aacttctggg ctcaagcaat tctcccacct cagcctccag
     1921 agaagctagc actgcagatg catgccacca caagggtaac tttgtatttt ttgtagcgac
     1981 aggatctcac gatgttgccc aggctagtct tgaactcctg gcctcaagca atcctgccat
     2041 ctcggcctcc ccaaatgctg ggattacagg catgagccgt gacaccggcc aagttctatt
     2101 ctgaagatga ggaagctaag ttatgaagag attaagttaa ttagccaaag gtcttgtcac
     2161 tgacatggaa aagctagaat tgaacctatt ctttaaatta gagctgggga taagaagtac
     2221 acatttctca gggcctgtga agaggggaag tcagtctgtt ccagaaaggg aggaagagct
     2281 ggattgaaaa caagagacac attctagcta gcaccaatgg agtgagccca gaactagaaa
     2341 tatgctgtct ctatgggttt aggaggaatc acccagtgtc agagaattag ggatacacct
     2401 tatgagtttg gccaaactgg ctgtagtatt tctgtgtttt ttagtagacg tgttaatacg
     2461 aaagagtgtg tcacattcaa atattaaatt gggccaggca cagtgcctca cacctgtaat
     2521 tccaaaattt ggggaggccg tgacaggagg atcactggag tccaggagtt caagaccagc
     2581 ctgggcaaca aagtgaaacc ttatctctac aaaaaaatta aaaaattagc tagacatggc
     2641 tgcatgtgcc tgtagtacca gctactcaag aggctgaggt gggaggatca cttgagccca
     2701 ggaggttgag gctgcagtga gcagtaattg tgccactgcc ctccagcctg agtgacagag
     2761 tgagaccttg tcccaaaaaa ttaaattaaa ttaaattaaa cgctttgcaa aaaaaaaaaa
     2821 ctacccatta aatccgggtt cctgggttat attagaagtt ccggccgggt gcagtggctc
     2881 atgcctataa tcccagcact ttgggaggct gaggtgggtg gatcacgagg tcaggagttt
     2941 gagaccagcc tgaccaacat agtgaaaccc cgtctctact aaaaatacaa aaaattaccc
     3001 gggcgtggtg gcacatgcct gtaatcccag ctactcagga ggctgaggca ggagaattgc
     3061 ttgaatccag gaggcgaagg ttgcagtgag ccgagattgg gccatggcac tctagcctgg
     3121 gtgacagagc gagactctgt ctcaaaaaaa caataaaaaa aagaagaaga agttctaggg
     3181 cacttaacta ctaatatctg ggggggcatt ctttgcctcc cctataaaat gtaaagggat
     3241 cccaaatgtt aaacttccac ccccatcacc tcgagttgtc atggaaaaga gaatgttata
     3301 ccctgtttat accccacgtg tcctggggtg tagctagtgc tttctagctg atcatgattc
     3361 tgaagatacc ttggaatagg ctgggaaaca ggtaaaaatc agactgtgtg agtttgaaag
     3421 agtgcaggaa aggtggcttc tgggttatat ccaagatgtg tcattgtggt tccccgtggt
     3481 gatcagaaaa gcgagccagc ttgctgtagt ttggttgacc aatgtccatg cattctgaaa
     3541 ttaaaataag ctttgtgatt actccttcac tttatttagt agtagtcatt gtgtaaattt
     3601 gaaacaaccg gagaagttgg gcttagtgtt gtttttatac atggcatatt ctagaccctg
     3661 agggccaggt cagggtgagg tgagggagac acctcacctc ctttaaacat tatttaaaat
     3721 gttgacattt tgttcaccgt ggattttttt tgcattcatt ttggtttttt aaaatattgc
     3781 attaggccgg gtgtggtggc tcactcctgt aatcccagca ctttgggaag ccgaggcagg
     3841 tggatcattt gaagtcagga gttcgacacc agcctggcca acatggtgaa accctgtgtc
     3901 tactaaaaat acaaaaatta gctgggtgtg gtgtgcgtgt gtggtcccag ctactcgaga
     3961 ggctgaggca ggataattgc tttaaccggg gagacagatg ttgcagtgag tcaagatcgt
     4021 gccactgcac tccagcctgg gcgacaagag tgacactcca tctaaaaaaa aaaaaaaaaa
     4081 aaaaaaagca taaacgtaat ttatcttgat tgctgaattt tttgatggcc ccttacattg
     4141 ggtgctcaaa gtgactgcct tatctcccca caaaggaaaa acaaaacgct tgcatttttc
     4201 cctcaaaaga ctaaaaaata gaagccatca ttaatttaaa ataggattaa gtgccaaaag
     4261 ttcagtgaga acacagcagg tctgggggtg tcaactctcc atgccccagg tgtggaaaca
     4321 gtccccctct gcctgctagc tttggccagc cccctccccc gggaccctgt cctcatctcc
     4381 ccccattaat cagccttcac tttctgaagt ctcacacctc ctgcattcct cactgtttgc
     4441 caagccttga taatggtccc ctctgtgatt ggtatcccca aggcaggacc agagcccaga
     4501 gaggtgatta aggggcagga gatcccaggc ttcagggacc tgctccctga gttccttgga
     4561 gcccagtgtt gtagtcctaa ttgctagaga ccaaggccag cttgaaagat gtgatctgtg
     4621 tccttcactt cttttgttct tttcttcccc ggtgctggcc taacctcctt gcatgtggat
     4681 aaaaattcaa tcccctcctc atggaggttg tccctcttgt ttcaccccca aaatcctcca
     4741 gtttctgtct gccaagcagc tagaaggagc tttttttttt tttttttttt tttgagatgg
     4801 aatctagctc tgtctcccag cctggagtgc agtggtgcta tctcggctca ctgcagcctc
     4861 tgcctcccgg gttcaagcga tttttctgcc tcagcttccc aagtagctgg gattgcaggc
     4921 acatgccacc acacccaact attttttgta tttttagtag agacggggtt tcgccatgtt
     4981 agccagactg gtctcggact cctgatttca ggtgatacta ccacctcggc ctcccaaggt
     5041 gccgggatta caggtgtgag ccaccacatc cagccagaag gatctttcta aagggaaact
     5101 ctgaaaaatc atccctctac ttaaaccttc tgtttctctt aggatacagt atagactcta
     5161 gtgtgatcat cagggctgcg tggccaggtc tatacttcat ccccaaattc attctttgac
     5221 cctatagccc aatgggctcc ctgctgtccc ggcagtaaac caagcacacc cggaccccag
     5281 gaaccttgca tctactcttt tttttttctt cagagattgg ggcatgaaat cttccattcc
     5341 tctttgcatt gctggtttgc attattgggg gtattagaag acactggctt ttggcaagag
     5401 gagtctagat tccaggtttg gtgctaactg acaaagtatc ttgcggcagg tagaaataat
     5461 cagttttctt gcattttttc cctcgaaaga ctaaaaaatg gaagccatca ttaatttaaa
     5521 acaggattaa gtgccaaaag ttcagtgaaa acacagccac atctgtgttt tctctgtgtt
     5581 agtatctcac acacaattcc actccaaata catccctgat gctgatgaaa cgttatgtat
     5641 ataattgtat gttgtctaca aggtaaacct taaaagtatg acaaatagag gttactatat
     5701 gttcattgaa tgtctttttt tttttttgag agagagagag agagagaaat aagatctcac
     5761 tctgtcaccc atgctggagt gcagtggcat gatctcagct cactgcaacc ttcacctccc
     5821 aggttcaaac aattctcctg tgtcagactc cctggaatta caggcgtgcc accatgcctg
     5881 gctaaatttt ttttgtgttt ttagtacaga cagggtttcg ccatgttgcc caggatggtt
     5941 tcaaactcct ggcctcaagt gacctgccca ccttggcctc ccaaagttct ggggttacag
     6001 gcatgagcca ccacgcctgg ccccttgcat ctactcttgc ttttgcctgt aatacccttc
     6061 ccccacctgc tcgcacactc ccttcggtct tcctgagggt cacctcctca gaaagctctt
     6121 tcctgacttc tccacactcg gtcaccaccc ctattacaag ccctcatagc aactcactta
     6181 ggtccctcag agcttttatc acaagttccc atatatatta attggtgcaa ttatttgttt
     6241 atttatgtct tcctctttct agggcagaca ttgagatcgg gatgtcttat ctaattggtt
     6301 caaccctgtc ttcccagtgg tgcctagaaa aatgcctggt acacagtagg tgctcaataa
     6361 atgctttttg agtgaa
//
