LOCUS       NM_001004463            3449 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 10 subfamily G member 7
            (OR10G7), mRNA.
ACCESSION   NM_001004463 XM_372437
VERSION     NM_001004463.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3449)
  AUTHORS   Tham,E.H., Dyjack,N., Kim,B.E., Rios,C., Seibold,M.A., Leung,D.Y.M.
            and Goleva,E.
  TITLE     Expression and function of the ectopic olfactory receptor OR10G7 in
            patients with atopic dermatitis
  JOURNAL   J Allergy Clin Immunol 143 (5), 1838-1848 (2019)
   PUBMED   30445058
  REMARK    GeneRIF: OR10G7 is expressed at significantly greater levels in
            undifferentiated keratinocytes from patients with atopic dermatitis
            compared with healthy control subjects
REFERENCE   2  (bases 1 to 3449)
  AUTHORS   Kosova,G., Scott,N.M., Niederberger,C., Prins,G.S. and Ober,C.
  TITLE     Genome-wide association study identifies candidate genes for male
            fertility traits in humans
  JOURNAL   Am J Hum Genet 90 (6), 950-961 (2012)
   PUBMED   22633400
REFERENCE   3  (bases 1 to 3449)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP001884.4.
            
            On Aug 5, 2020 this sequence version replaced NM_001004463.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641585.1/ ENSP00000492905.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-440               AP001884.4         92632-93071         c
            441-3449            AP001884.4         87759-90767         c
FEATURES             Location/Qualifiers
     source          1..3449
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q24.2"
     gene            1..3449
                     /gene="OR10G7"
                     /gene_synonym="OR11-283"
                     /note="olfactory receptor family 10 subfamily G member 7"
                     /db_xref="GeneID:390265"
                     /db_xref="HGNC:HGNC:14842"
     exon            1..440
                     /gene="OR10G7"
                     /gene_synonym="OR11-283"
                     /inference="alignment:Splign:2.1.0"
     exon            441..3449
                     /gene="OR10G7"
                     /gene_synonym="OR11-283"
                     /inference="alignment:Splign:2.1.0"
     CDS             461..1396
                     /gene="OR10G7"
                     /gene_synonym="OR11-283"
                     /note="olfactory receptor OR11-283"
                     /codon_start=1
                     /product="olfactory receptor 10G7"
                     /protein_id="NP_001004463.1"
                     /db_xref="CCDS:CCDS31705.1"
                     /db_xref="GeneID:390265"
                     /db_xref="HGNC:HGNC:14842"
                     /translation="MSNATLLTAFILTGLPHAPGLDAPLFGIFLVVYVLTVLGNLLIL
                     LVIRVDSHLHTPMYYFLTNLSFIDMWFSTVTVPKMLMTLVSPSGRTISFHSCVAQLYF
                     FHFLGSTECFLYTVMSYDRYLAISYPLRYTNMMTGRSCALLATGTWLSGSLHSAVQTI
                     LTFHLPYCGPNQIQHYFCDAPPILKLACADTSANEMVIFVNIGLVASGCFVLIVLSYV
                     SIVCSILRIRTSEGRHRAFQTCASHCIVVLCFFGPGLFIYLRPGSRDALHGVVAVFYT
                     TLTPLFNPVVYTLRNKEVKKALLKLKNGSVFAQGE"
ORIGIN      
        1 agataattag ctcctttata actaaaaccc atatttacta ttattaaatt taaaaaagaa
       61 ataggaaaaa aatcattccc tgcacaagga gttttcagat ccagagtgtc atagttattc
      121 attttggaag ttgatttttg gctaaataaa aaggtttatg gaatgatggc catccaatgc
      181 agaatcaact ttagcagatg catttggaaa aaattccaag tgtttatcat gatgtcaaca
      241 cattatcttc actcataagg actgtagagc taacggagtg tctcctaaga catcaaattc
      301 atattaagtt ctatttaaaa agagtttctt ctgtggtttc atctttgcaa gaaaagaaaa
      361 attataccac ttatcaagaa ctgacatttt ctttcaatat tgaattttgc ttcatgatcc
      421 aaaacctagt tgtaaaattg agccccatat atgagaagaa atgtccaacg ccaccctact
      481 gacagcgttc atcctcacgg gccttcccca tgccccaggg ctggacgccc ccctctttgg
      541 aatcttcctg gtggtttacg tgctcactgt gctggggaac ctcctcatcc tgctggtgat
      601 cagggtggat tctcacctcc acacccccat gtactacttc ctcaccaacc tgtccttcat
      661 tgacatgtgg ttctccactg tcacggtgcc caaaatgctg atgaccttgg tgtccccaag
      721 cggcaggact atctccttcc acagctgcgt ggctcagctc tattttttcc acttcctggg
      781 gagcaccgag tgtttcctct acacagtcat gtcctatgat cgctacctgg ccatcagtta
      841 cccgctcagg tacaccaaca tgatgactgg gcgctcgtgt gccctcctgg ccaccggcac
      901 ttggctcagt ggctctctgc actctgctgt ccagaccata ttgactttcc atttgcccta
      961 ctgtggaccc aaccagatcc agcactactt ctgtgacgca ccgcccatcc tgaaactggc
     1021 ctgtgcagac acctcagcca acgagatggt catctttgtg aatattgggc tagtggcctc
     1081 gggctgcttt gtcctgatag tgctgtccta tgtgtccatc gtctgttcca tcctgcggat
     1141 ccgcacctca gaggggaggc acagagcctt tcagacctgt gcctcccact gtatcgtggt
     1201 cctttgcttc tttggccctg gtcttttcat ttacctgagg ccaggctcca gggacgcctt
     1261 gcatggggtt gtggccgttt tctacaccac gctgactcct cttttcaacc ctgttgtgta
     1321 caccctgaga aacaaggagg taaagaaagc tctgttgaag ctgaaaaatg ggtcagtatt
     1381 tgctcagggt gaatagttaa gaaaggccat atatggctaa cttttctttt tttatttgta
     1441 attaaattaa accttcaaca taagcattat acttgaatgg agcatttcaa ttattcagtc
     1501 ttaattttta attggacagt taattaattt ttcatttttt tctgcagagt gtttgttaga
     1561 atcctagtta aagcagccat ttcacggtga taatctaaga gaaaggataa tagtctattc
     1621 ttttcacgtt ccattaagta atcagaaaag taatttattt tcttatataa atattttcca
     1681 gaattgttat tcagtataat gttcttacag tttattttgt gtcatttaag tcaaagcctt
     1741 ataaaaatct tttcatgttt taaactttct atattgaaaa attcattata gcattcataa
     1801 ataactacat aatttaatat ccataagata aaatttttac tttagaaaat actagacaaa
     1861 aaggcttggt tctcaagaag aatggcttta ttcacattca tgggccaata aaaaccatat
     1921 aactctttaa tatttttttc ttactttggc ctgaaagatt tctgagagta aatatttgtc
     1981 catttatgca ctgtatacac tgtacacatt gtattggtct ctgatgacaa ctatctagac
     2041 tttccttcca tatttgtgga gctgccaatc tcttatcctc aatggcaagt ttccattttc
     2101 agcaatttta aaattatttt tataagtacc agaggataaa taataaatat acaaaaatga
     2161 tcaaataatc ttagagacaa aaatatgcag tcaaaaactg ttaagagtat cccttaattt
     2221 agaataaagt actagataat atttcccatg taattagact atgtctgcaa gtcacattcg
     2281 tttgtttgac ttaaagtata tgaaatggac tctgtacact ctctgggtag gtaaggctca
     2341 gaccatgaac cttataatct gtcatccaaa taaatacata tatttaaagt gtaaataaat
     2401 ttttctcaaa ataaatgttt aatttaaata ccacaggtat cctggtcatg ccaactctgc
     2461 ctagcatagc atgaagagta aaagaaaact agaaggcagc tgctagaact gaaaagcatt
     2521 tctcaaactc ctcagatttg cagcagctgc atttcaaaga tgctttagca agaatgctcc
     2581 tttgtgccaa ctttccatat cttgctccaa gtaaactgtg cggtgatatt gagaagaaaa
     2641 acatactaac ttggtaagca tgagctacat aaaccatgac acagtacatg aagcatgaac
     2701 tacataaacc atgatcagta taagaggtaa atttttggtt ttcacaccaa gaaaccagat
     2761 tgctatggac caattatata attcagctca tttctcaaag gaaaaaactg aggtagacat
     2821 aaaccaaaat tacttagtca ttggattcac ttggattctt acacttctct gtaacatcac
     2881 gctgttatat ctaacttacc attacctaaa atgttatggg atatttattg ggtgttaagt
     2941 cacatgctaa acagtagata cgcaaaaaca atagacaagg tctctgcatt caccaaagtc
     3001 attgtctggc aagggggaaa aatatgttgc attgtccagg ttacattgtt gtaagtgcaa
     3061 tggatgccca aggagagatt cattattagt tttgacttgg aaagatgcta aaggattcaa
     3121 aatactatgg caatatgtat cacacacaac cattttgaaa gtaaattatt gataaacata
     3181 tataagaaga atgtcagtct ttatttaatt gaaaatgttg ttgaaataat tttagaatcg
     3241 catgaagttg taagaaataa cacagtgata gttcttgtta taccttgccc agtttccccc
     3301 aatggtaaca gttagcaaaa ttgtagtgca atatcacaac tgggatattg acattattat
     3361 aatccacaaa tcttattcag atttttctag ttttactcac gtgtatgtgt gtgtatttgt
     3421 taaatactat acagttttaa caccagtgt
//
