LOCUS       NM_001005466            1105 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 10 subfamily G member 2
            (OR10G2), mRNA.
ACCESSION   NM_001005466
VERSION     NM_001005466.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1105)
  AUTHORS   Lin,C.W., Chang,Y.L., Chang,Y.C., Lin,J.C., Chen,C.C., Pan,S.H.,
            Wu,C.T., Chen,H.Y., Yang,S.C., Hong,T.M. and Yang,P.C.
  TITLE     MicroRNA-135b promotes lung cancer metastasis by regulating
            multiple targets in the Hippo pathway and LZTS1
  JOURNAL   Nat Commun 4, 1877 (2013)
   PUBMED   23695671
  REMARK    GeneRIF: Expression of miR-135b, LZTS1, LATS2 and nuclear TAZ
            predicts poor outcomes of non-small-cell lung cancer.
REFERENCE   2  (bases 1 to 1105)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   3  (bases 1 to 1105)
  AUTHORS   Koop,B.F., Rowen,L., Wang,K., Kuo,C.L., Seto,D., Lenstra,J.A.,
            Howard,S., Shan,W., Deshpande,P. and Hood,L.
  TITLE     The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region:
            organization, sequence, and evolution of 97.6 kb of DNA
  JOURNAL   Genomics 19 (3), 478-493 (1994)
   PUBMED   8188290
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC243972.3.
            
            On Apr 16, 2014 this sequence version replaced NM_001005466.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC137371.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000542433.1/ ENSP00000445383.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1105              AC243972.3         132837-133941
FEATURES             Location/Qualifiers
     source          1..1105
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q11.2"
     gene            1..1105
                     /gene="OR10G2"
                     /gene_synonym="OR14-41"
                     /note="olfactory receptor family 10 subfamily G member 2"
                     /db_xref="GeneID:26534"
                     /db_xref="HGNC:HGNC:8170"
     exon            1..1105
                     /gene="OR10G2"
                     /gene_synonym="OR14-41"
                     /inference="alignment:Splign:2.1.0"
     CDS             99..1031
                     /gene="OR10G2"
                     /gene_synonym="OR14-41"
                     /note="olfactory receptor OR14-41 pseudogene"
                     /codon_start=1
                     /product="olfactory receptor 10G2"
                     /protein_id="NP_001005466.2"
                     /db_xref="CCDS:CCDS32047.1"
                     /db_xref="GeneID:26534"
                     /db_xref="HGNC:HGNC:8170"
                     /translation="MGKTKNTSLDAVVTDFILLGLSHPPNLRSLLFLVFFIIYILTQL
                     GNLLILLTMWADPKLCARPMYILLGVLSFLDMWLSSVTVPLLILDFTPSIKAIPFGGC
                     VAQLYFFHFLGSTQCFLYTLMAYDRYLAICQPLRYPVLMNGRLCTVLVAGAWVAGSMH
                     GSIQATLTFRLPYCGPNQVDYFICDIPAVLRLACADTTVNELVTFVDVGVVAASCFML
                     ILLSYANIVNAILKIRTTDGRRRAFSTCGSHLIVVTVYYVPCIFIYLRAGSKDPLDGA
                     AAVFYTVVTPLLNPLIYTLRNQEVKSALKRITAG"
ORIGIN      
        1 ggcatcaatc atccgacaaa agcattcact tacaacatca ttgtgctgtg tttctcttgt
       61 caaacgtcac cattcatctt agcagactac aaaaagacat gggaaagacc aaaaacacat
      121 cgctggatgc cgtggtgaca gatttcattc ttctgggttt gtctcacccc ccaaatctaa
      181 gaagcctcct cttcctggtc ttcttcatca tttacatcct cactcagctg gggaacctgc
      241 tcattctgct caccatgtgg gctgacccga agctctgtgc tcgccccatg tacattcttc
      301 tgggagtgct ctcattcctg gacatgtggc tctcctcagt caccgttcct ctgcttattt
      361 tggattttac tccttccatc aaggctatcc cgtttggtgg ctgtgtggct caactgtatt
      421 tctttcactt cctgggcagc acccagtgct tcctctacac cttgatggcc tatgacaggt
      481 acctggcaat atgtcagccc ctgcgctacc cagtgctcat gaatgggagg ttatgcacag
      541 tccttgtggc tggagcttgg gtcgccggct ccatgcatgg gtctatccag gccaccttga
      601 ccttccgcct gccctactgt gggcccaatc aggtggatta ctttatctgt gacatccccg
      661 cagtattgag actggcctgt gctgacacaa ctgtcaatga gcttgtgacc tttgtggacg
      721 tcggggtagt ggccgccagt tgcttcatgt taattctgct ctcgtatgcc aacatagtaa
      781 atgccatcct gaagatacgc accactgatg ggaggcgccg ggccttctcc acctgtggct
      841 cccacctaat cgtggtcaca gtctactatg tcccctgtat tttcatctac cttagggctg
      901 gctccaaaga ccccctggat ggggcagcgg ctgtgtttta cactgttgtc actccattac
      961 tgaaccccct catctataca ctgaggaacc aggaagtgaa gtctgccctg aagaggataa
     1021 cagcaggttg aaggactgaa tgaaaataag taactacatc tgcatcatta tcactgccac
     1081 tctcttcagc tactgctgca tgtga
//
