LOCUS       NM_001004461            6052 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 10 subfamily A member 6
            (gene/pseudogene) (OR10A6), transcript variant 1, mRNA.
ACCESSION   NM_001004461 XM_372373
VERSION     NM_001004461.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6052)
  AUTHORS   Olender,T., Waszak,S.M., Viavant,M., Khen,M., Ben-Asher,E.,
            Reyes,A., Nativ,N., Wysocki,C.J., Ge,D. and Lancet,D.
  TITLE     Personal receptor repertoires: olfaction as a model
  JOURNAL   BMC Genomics 13, 414 (2012)
   PUBMED   22908908
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6052)
  AUTHORS   Menashe,I., Aloni,R. and Lancet,D.
  TITLE     A probabilistic classifier for olfactory receptor pseudogenes
  JOURNAL   BMC Bioinformatics 7, 393 (2006)
   PUBMED   16939646
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6052)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC044810.7.
            
            On Jan 5, 2021 this sequence version replaced NM_001004461.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. This olfactory receptor gene is a
            segregating pseudogene, where some individuals have an allele that
            encodes a functional olfactory receptor, while other individuals
            have an allele encoding a protein that is predicted to be
            non-functional. [provided by RefSeq, Jun 2015].
            
            Sequence Note: This gene is a segregating pseudogene. This RefSeq
            represents the protein encoded by the reference genome allele,
            which is predicted to be non-functional as an olfactory receptor
            according to the Classifier for Olfactory Receptor Pseudogenes.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641238.1/ ENSP00000493068.1
            polymorphic pseudogene :: PMID: 22908908
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-72                AC044810.7         152065-152136       c
            73-99               AC044810.7         151855-151881       c
            100-128             AC044810.7         151729-151757       c
            129-6052            AC044810.7         145460-151383       c
FEATURES             Location/Qualifiers
     source          1..6052
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..6052
                     /gene="OR10A6"
                     /gene_synonym="OR11-96"
                     /note="olfactory receptor family 10 subfamily A member 6
                     (gene/pseudogene)"
                     /db_xref="GeneID:390093"
                     /db_xref="HGNC:HGNC:15132"
     exon            1..72
                     /gene="OR10A6"
                     /gene_synonym="OR11-96"
                     /inference="alignment:Splign:2.1.0"
     exon            73..99
                     /gene="OR10A6"
                     /gene_synonym="OR11-96"
                     /inference="alignment:Splign:2.1.0"
     exon            100..128
                     /gene="OR10A6"
                     /gene_synonym="OR11-96"
                     /inference="alignment:Splign:2.1.0"
     exon            129..6052
                     /gene="OR10A6"
                     /gene_synonym="OR11-96"
                     /inference="alignment:Splign:2.1.0"
     CDS             1982..2926
                     /gene="OR10A6"
                     /gene_synonym="OR11-96"
                     /note="isoform 1 is encoded by transcript variant 1;
                     olfactory receptor 10A6; olfactory receptor OR11-96;
                     olfactory receptor, family 10, subfamily A, member 6"
                     /codon_start=1
                     /product="olfactory receptor 10A6 isoform 1"
                     /protein_id="NP_001004461.1"
                     /db_xref="GeneID:390093"
                     /db_xref="HGNC:HGNC:15132"
                     /translation="MERQNQSCVVEFILLGFSNYPELQGQLFVAFLVIYLVTLIGNAI
                     IIVIVSLDQSLHVPMYLFLLNLSVVDLSFSAVIMPEMLVVLSTEKTTISFGGCFAQMY
                     FILLFGGAECFLLGAMAYDRFAAICHPLNYQMIMNKGVFMKLIIFSWALGFMLGTVQT
                     SWVSSFPFCGLNEINHISCETPAVLELACADTFLFEIYAFTGTFLIILVPFLLILLSY
                     IRVLFAILKMPSTTGRQKAFSTCAAHLTSVTLFYGTASMTYLQPKSGYSPETKKVMSL
                     SYSLLTPLLNLLIYSLRNSEMKRALMKLWRRRVVLHTI"
ORIGIN      
        1 aataggtggc ttttgactac aggtgaatct tctgataaag tagtatgaaa attaaagaga
       61 cagagtcaac agagaaaggt tcgggcaata agtagaagtg ctgaagcctt ggggaggaag
      121 tgatctgcgt ctgcactcaa gacagcactg tatgccttca acttgctgtg tccatctgtc
      181 ttcctggctt cctcatctct cacagtgaat ttcttttggt tttcaaaaca tcacacaaaa
      241 ggcagtaggc ttccattcta gttttatggt gtcaccaagt gcctcctgac ttgagcaagt
      301 cagttttcct cctcctgcca tcctcctccg acctaatggc cttccattca tgacatcctg
      361 tgattgtgtt tgttcatcct ccaccccctt caaatgtcat cattccctta cttaaatttc
      421 tacagcacgt gttattaatt tccaattgtg ttgtgtgctg acttctctta ggcactctat
      481 tccttaaaaa tagagtctag gtttttctta ttttaaaatt catttattca aaaatgttgg
      541 tttaaaacct attatgagcc agggagggtt gtagtgtagg cagtgtgtgt agagcaaaga
      601 agcaaacaaa atctttgccc tctgggagct aagctctagt gagggatttt atatatatat
      661 atatatatat atatatacat acacatacac ataccttact agagcttata tatatataat
      721 atatataaaa tattaatctg tttatattta tataaatatt taaaatatat tttacacata
      781 tttcttaaaa aaaggataga ggatatatta tattctatgc catataatgt tataaaatca
      841 atgaactgaa tcactcagtt gtgtatatat atgtgtgcat gtgtgtgtat atatatatat
      901 atatatatat atatatatat gtacacatag aaagagagag agaaagaaag agaaagtcct
      961 ggggtatgcg gtacggggag gtactagttt atgcagcata ctggttaagg ggttagaagc
     1021 tattttatgt agtgtgctta gctctctgtt gagctctgga ttcatgtgta ttcctaaggg
     1081 tgcagagcct agaaaatggt agctggttaa tcagtgcttg ttgaataatt aatgattaaa
     1141 tgaatttttt gatgacgagt atagtgggaa gagagaagag agaaaaggag agagagagtg
     1201 aaatctttta aattacacaa tgatccccca aatggttttt ttcttaagtc atcatggtca
     1261 gaaggataga ccttggagat ctggccccaa aaacttcaca tccaggtaaa tcccaatata
     1321 attggccaga tccaggatgg gcagaaatct gcaagcttga agccaattca catagtctat
     1381 aggtcaccta atatggttgt gttgaaaatt caaatcccct ctatgtttct acagaatgtt
     1441 gttttctttc tccaagtcat atataggtac tttgaatcta attaatattt taaataagtt
     1501 tatatcaaat atgctgtaac attggattat taggctatta tcacatttgt tgagatatct
     1561 ttttcaatct atctgctttt ttatatttta ttttttgtag tcttaagttt tgcatttatg
     1621 taaaattcag ttaaataaag aacacttgca ccaatgttat gggattggaa cctaaggtat
     1681 aaagtattta tatttccatt aaggctatgt ttaattttca aataatatca aataaatttt
     1741 gatattattt gacaagatct ctgagccaga attcttcatt tctatttttt atatttggaa
     1801 tataatccaa gtatttggtc attgtctaaa attgccaaag aaaatttctg tcaggatagg
     1861 ctcctcatct tctgccagaa tttctggggt gaatgcagac tggaactctt agctaatgga
     1921 ctgtggcttt attctgtata tactatgtcc ataaaatcaa tgcacgactt cattactgaa
     1981 aatggaaaga caaaatcaaa gctgtgtggt tgaattcatc ctcttgggct tttctaacta
     2041 tcctgagctc caggggcagc tctttgtggc tttcctggtt atttatctgg tgaccctgat
     2101 aggaaatgcc attattatag tcatcgtctc cctagaccag agcctccacg ttcccatgta
     2161 cctgtttctc ctgaacttat ctgtggtgga cctgagtttc agtgcagtta ttatgcctga
     2221 aatgctggtg gtcctctcta ctgaaaaaac tacaatttct tttgggggct gttttgcaca
     2281 gatgtatttc atccttcttt ttggtggggc tgaatgtttt cttctgggag caatggctta
     2341 tgaccgattt gctgcaattt gccatcctct caactaccaa atgattatga ataaaggagt
     2401 ttttatgaaa ttaattatat tttcatgggc cttaggtttt atgttaggta ctgttcaaac
     2461 atcatgggta tctagttttc ccttttgtgg ccttaatgaa attaaccata tatcttgtga
     2521 aaccccagca gtgttagaac ttgcatgtgc agacacgttt ttgtttgaaa tctatgcatt
     2581 cacaggcacc tttttgatta ttttggttcc tttcttgttg atactcttgt cttacattcg
     2641 agttctgttt gccatcctga agatgccatc aaccactggg agacaaaagg ccttttccac
     2701 ctgtgccgct cacctcacat ctgtgaccct attctatggc acagccagta tgacttattt
     2761 acaacccaaa tctggctact caccggaaac caagaaagtg atgtcattgt cttactcact
     2821 tctgacacca ctgctgaatc tgcttatcta cagtttgcga aatagtgaga tgaagagggc
     2881 tttgatgaaa ttatggcgaa ggcgagtggt tttacacaca atctgactgt gttgagaagc
     2941 catgtaagat ttagtcactg catgactgta ttcaatctaa atttaataaa tttagattca
     3001 ttaagtttgc attttttggc atgagtatga ctaatttatt gtgttctcca agtttgattg
     3061 tatatcagga gcatctttat atgttaatgt ttttagtttt ttcaccagtg cataatattc
     3121 cttaatattg aatataacac aatttcaaca atttgtttag tagtagccct actgatggtt
     3181 atttttttgt cacaatagat aatactaaaa caaccagttt ttatatattc ataaattctg
     3241 gtgctttaat ttttacagaa tagctttcac aaagtaggtt tgaagggtca aaacaaatgt
     3301 gagtttgcaa gttttcatag atattactga gttacttttt taaatgattt taacaacttc
     3361 agactgacct gagcacccat cctatccctc tactatgttg tatgccaaga agcctacaat
     3421 aacgagatga gattttctgc ttctgtagtg aaaatctgtt ccatacataa gtaggaaaga
     3481 acagttattt attgagagga acacaatgtc tctactcagg gacccagaga gtctataatt
     3541 caaaactaga tatcttctgg ttattttaga atatatattc ctccagtgtt ttgagtagag
     3601 aacatcatgt gatcattttt gaaggtcatt taaagtacgg ctgtcctttc cacttataaa
     3661 ctatattttt tgaaacttgg tcaaatttct ttcataaggc aaaaatgcac ctcatacagg
     3721 ccaaacaatg tatgattgtg tttttttgtt gtgggacata aatatgatta cctcattgtg
     3781 cctattttct attatccttg ggtcatatca atatttatgt gcatctttcc aacataaaat
     3841 aatcacataa tagtctttct agttatatat aaagatgaat aattagacac attgcaacat
     3901 tgaaatataa catttcattc ttgcttccta ttttaatatt gctataataa atagaaaggg
     3961 ttcttctcat taaatctata tcaaaggagt tgacaacacc cttcatttct gctctggggg
     4021 tggaggtggg gtaataaagc ggttagaaca cttctacaaa acaatcattc attggatgga
     4081 aaacccttct tttcttcact actccttctg ccaaaaataa aggtgaagtt gcaaatctat
     4141 ttgaatttca aaaaaagaga gaaatttcat gagaagaagg ctggaacctt gtgggtaatg
     4201 atgcaggact tttcttctca gtcactttgg aagctgggga cccctgaccg gcaacagccc
     4261 acctggcatg ccccagctca cctctgttat agcttgtacc tgcattcagc agttcccaag
     4321 cttttgtacc acacccaaga agaatgagga tatgctgggc attgaagggt aaggatggtg
     4381 gagaagaatt ttactgaagg acagaacaac tgtcagcaga gaggggatat ggggggtggt
     4441 tcccctactg gaaggcagga aagccccacc atggtggctg ggtccaggac cttttaggga
     4501 ctcaaaatgg gaagtacatg ctggtttgtg aggtatgcaa aaaggttaaa gtgaagacac
     4561 cactcaaagg tgggcatgac agtgtagaaa aaccaattag gaaagggtag gtatatgtaa
     4621 aataggtgaa gagcggggaa caatcagagg aaagtatgtg aaatgggaag ataagttctc
     4681 aatccggtcc cagagtttaa cttgcagttt ggctttcagg ctttaaactg tcttttgttt
     4741 agaggtgggg tttcaccagg aacccacccc atctgcctag gcatttggct gcctcctgtc
     4801 gctatcagtg atatctgaat gttgtataat actgttttca tttgggcacc aaacagccct
     4861 cagcaaaagc ctttgattgg atcccatctc ttgatatcct gaaatttcct tctgatagct
     4921 tttaaaagaa ccaattaagt aagacttatg taaaacgaac aaatcagcaa agaaacaaac
     4981 aaaggaagct aaatacagaa agtcttttta gccattcttt agttcatttt gttcattgat
     5041 tctgtaaacc aatttttttc ttaaaaaaaa ttctttataa aaatgtctta agagagctaa
     5101 atctaatgaa atagtctctg ctcttgaagg atttacagtg tactggtcat tagatgctgg
     5161 aaggttacta tatttgacgc tttcctcttt cattgccttt gtgataaata aagcctggat
     5221 tggcaagatg ttcatgaaat tacaataaga aattaggtca ctctaattct aaatttgtat
     5281 gtgtgtgtgt atatgcgtgt gtgaatccaa gtatgtgctg ggaatttata catttgtgat
     5341 gttatgtgag gagatagaaa taatcgctag taaatttagt catagtttaa aatttttatg
     5401 ttattctgat gaatagaaat tgttagtatg cttcacacat aatagcctaa tcatatcatt
     5461 tctgcatact attcttcatg gtgattttta gttatagtca ccgtggctgc tactgctgct
     5521 agttttctag tttatgccca ttctcctttt tctttaatag agaaaacccc atttttgttc
     5581 tttaagtaga aaaaaaaaac aagtttctta agggcagtaa tgtatccagt taataaccaa
     5641 tttcccagtt tctcttttga acaagggtgg tttgtgacac agttctgact agtgatatat
     5701 aggtggacat ccttgagtag ggtgtctatg aaaactcttt aaaaatgtga cttagttaat
     5761 aaggactttt tgctcttcaa cctcctcctt ccttctacct gaaacaagcc atgaggctag
     5821 agatagtgca gctatcttgc aatgagagtt aaagcatgac tagaaaagcc aggccctaca
     5881 gaggccaagt ggaaagctag agggcccctg ggtctgtgac ggcattgcgt agtgacctta
     5941 tcattcctct cctgcctatt tgtttactga ctgttacttc agagaaataa accttgtctt
     6001 tgtttaatcc agtatttgct aggttttctg ttacagcata acccaatcca ga
//
