LOCUS       NM_207186                995 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 10 subfamily A member 4
            (OR10A4), mRNA.
ACCESSION   NM_207186
VERSION     NM_207186.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 995)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 995)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
REFERENCE   3  (bases 1 to 995)
  AUTHORS   Gaudin,J.C., Breuils,L. and Haertle,T.
  TITLE     New GPCRs from a human lingual cDNA library
  JOURNAL   Chem Senses 26 (9), 1157-1166 (2001)
   PUBMED   11705801
REFERENCE   4  (bases 1 to 995)
  AUTHORS   Lane,R.P., Cutforth,T., Young,J., Athanasiou,M., Friedman,C.,
            Rowen,L., Evans,G., Axel,R., Hood,L. and Trask,B.J.
  TITLE     Genomic analysis of orthologous mouse and human olfactory receptor
            loci
  JOURNAL   Proc Natl Acad Sci U S A 98 (13), 7390-7395 (2001)
   PUBMED   11416212
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC087280.11.
            
            On Jan 21, 2010 this sequence version replaced NM_207186.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC137024.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000379829.2/ ENSP00000369157.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-995               AC087280.11        107118-108112
FEATURES             Location/Qualifiers
     source          1..995
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..995
                     /gene="OR10A4"
                     /gene_synonym="JCG5; OR10A4P"
                     /note="olfactory receptor family 10 subfamily A member 4"
                     /db_xref="GeneID:283297"
                     /db_xref="HGNC:HGNC:15130"
     exon            1..995
                     /gene="OR10A4"
                     /gene_synonym="JCG5; OR10A4P"
                     /inference="alignment:Splign:2.1.0"
     CDS             24..971
                     /gene="OR10A4"
                     /gene_synonym="JCG5; OR10A4P"
                     /note="olfactory receptor, family 10, subfamily A, member
                     4 pseudogene; hP2 olfactory receptor; olfactory
                     receptor-like protein JCG5; olfactory receptor OR11-87"
                     /codon_start=1
                     /product="olfactory receptor 10A4"
                     /protein_id="NP_997069.2"
                     /db_xref="CCDS:CCDS7774.1"
                     /db_xref="GeneID:283297"
                     /db_xref="HGNC:HGNC:15130"
                     /translation="MMWENWTIVSEFVLVSFSALSTELQALLFLLFLTIYLVTLMGNV
                     LIILVTIADSALQSPMYFFLRNLSFLEIGFNLVIVPKMLGTLIIQDTTISFLGCATQM
                     YFFFFFGAAECCLLATMAYDRYVAICDPLHYPVIMGHISCAQLAAASWFSGFSVATVQ
                     TTWIFSFPFCGPNRVNHFFCDSPPVIALVCADTSVFELEALTATVLFILFPFLLILGS
                     YVRILSTIFRMPSAEGKHQAFSTCSAHLLVVSLFYSTAILTYFRPQSSASSESKKLLS
                     LSSTVVTPMLNPIIYSSRNKEVKAALKRLIHRTLGSQKL"
ORIGIN      
        1 ccagtgaagt cctgggcaga agaatgatgt gggaaaactg gacaattgtc agtgaatttg
       61 ttctcgtgag cttctcagcc ctgtccactg agcttcaggc tctactgttt ctccttttct
      121 tgaccattta cttggttact ttaatgggca atgtcctcat catcctggtc actatagctg
      181 actctgcact acaaagtcct atgtacttct tcctcagaaa cttgtccttc ctggagatag
      241 gtttcaactt ggtcattgtg cccaagatgc tggggaccct gatcattcaa gacacaacca
      301 tctccttcct tggatgtgcc actcagatgt atttcttctt cttttttggg gctgctgagt
      361 gctgcctcct ggccaccatg gcatatgacc gctacgtggc catctgtgac cccttgcact
      421 acccagtcat catgggccac atatcctgtg cccagctggc agctgcctct tggttctcag
      481 ggttttcagt ggccactgtg caaaccacat ggattttcag tttccctttt tgtggcccca
      541 acagggtgaa ccacttcttc tgtgacagcc ctcctgttat tgcactggtc tgtgctgaca
      601 cctctgtgtt tgaactggag gctctgacag ccactgtcct attcattctc tttcctttct
      661 tgctgatcct gggatcctat gtccgcatcc tctccactat cttcaggatg ccgtcagctg
      721 aggggaaaca tcaggcattc tccacctgtt ccgcccacct cttggttgtc tctctcttct
      781 atagcactgc catcctcacg tatttccgac cccaatccag tgcctcttct gagagcaaga
      841 agctgctgtc actctcttcc acagtggtga ctcccatgtt gaaccccatc atctacagct
      901 caaggaataa agaagtgaag gctgcactga agcggcttat ccacaggacc ctgggctctc
      961 agaaactatg attggcttag atggaaactg aaggg
//
