LOCUS       NM_024648               4249 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens 2-oxoglutarate and iron dependent oxygenase domain
            containing 3 (OGFOD3), transcript variant 1, mRNA.
ACCESSION   NM_024648 XM_941411
VERSION     NM_024648.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4249)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK025875.1 and AC132938.9.
            
            On Nov 22, 2018 this sequence version replaced NM_024648.2.
            
            Transcript Variant: This variant (1) encodes isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK025875.1, SRR1163655.604250.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000313056.10/ ENSP00000320116.5
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1235              AK025875.1         1-1235
            1236-4249           AC132938.9         74696-77709
FEATURES             Location/Qualifiers
     source          1..4249
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q25.3"
     gene            1..4249
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
                     /note="2-oxoglutarate and iron dependent oxygenase domain
                     containing 3"
                     /db_xref="GeneID:79701"
                     /db_xref="HGNC:HGNC:26174"
     exon            1..175
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
                     /inference="alignment:Splign:2.1.0"
     CDS             102..1061
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
                     /note="isoform 1 is encoded by transcript variant 1; PKHD
                     domain-containing transmembrane protein C17orf101;
                     2-oxoglutarate and iron-dependent oxygenase
                     domain-containing protein 3"
                     /codon_start=1
                     /product="2-oxoglutarate and iron-dependent oxygenase
                     domain-containing protein 3 isoform 1"
                     /protein_id="NP_078924.1"
                     /db_xref="CCDS:CCDS11811.1"
                     /db_xref="GeneID:79701"
                     /db_xref="HGNC:HGNC:26174"
                     /translation="MAPQRRAATKAPEGNGAAERRNRSSTKKDRAPREVQRLWQRPWL
                     RTAGLGAGFVLTALLLWSSLGADDGVAEVLARRGEVVAGRFIEVPCSEDYDSHRRFEG
                     CTPRKCGRGVTDVVITREEAERIRSVAEKGLSLGGSDGGASILDLHSGALSVGKHFVN
                     LYRYFGDKIQNIFSEEDFRLYREVRQKVQLTIAEAFGISASSLHLTKPTFFSRINSTE
                     ARTAHDEYWHAHVDKVTYGSFDYTSLLYLSNYLEDFGGGRFMFMEEGANKTVEPRAGR
                     VSFFTSGSENLHRVEKVHWGTRYAITIAFSCNPDHGIEDPAFP"
     exon            176..405
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
                     /inference="alignment:Splign:2.1.0"
     exon            406..481
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
                     /inference="alignment:Splign:2.1.0"
     exon            482..524
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
                     /inference="alignment:Splign:2.1.0"
     exon            525..589
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
                     /inference="alignment:Splign:2.1.0"
     exon            590..646
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
                     /inference="alignment:Splign:2.1.0"
     exon            647..800
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
                     /inference="alignment:Splign:2.1.0"
     exon            801..924
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
                     /inference="alignment:Splign:2.1.0"
     exon            925..4249
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1216..1221
                     /regulatory_class="polyA_signal_sequence"
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
                     /note="hexamer: AGTAAA"
     polyA_site      1235
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
                     /note="major polyA site"
     regulatory      2110..2115
                     /regulatory_class="polyA_signal_sequence"
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
                     /note="hexamer: AATAAA"
     polyA_site      2130
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
     regulatory      3320..3325
                     /regulatory_class="polyA_signal_sequence"
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
                     /note="hexamer: AGTAAA"
     polyA_site      3343
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
     regulatory      4228..4233
                     /regulatory_class="polyA_signal_sequence"
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
                     /note="hexamer: AATAAA"
     polyA_site      4249
                     /gene="OGFOD3"
                     /gene_synonym="C17orf101"
ORIGIN      
        1 actcgcgtcc ctgcgccgtg cctgcctcgc gctccctgtt acggcgttcg tccccgggcc
       61 tggcgcccgc gtccggcccg gctccgcggc ggcctggtcc gatggctcct cagcggaggg
      121 ccgcaaccaa ggcgcccgag ggcaacggag cggccgagcg ccggaaccgg agcagcacca
      181 agaaggaccg agccccgcgg gaggtgcaga ggctgtggca gaggccgtgg ctaaggaccg
      241 cgggcctggg ggctggcttt gtgctcaccg cactcctgct ctggagcagc ttgggggccg
      301 acgacggggt cgcagaggtc ctggcccgcc gtggcgaggt cgtggcaggg agattcatcg
      361 aggtgccctg ctctgaggac tacgacagtc accgcaggtt cgaaggctgc actccccgaa
      421 agtgcggcag aggtgtcacc gatgtcgtca tcaccaggga ggaagcggag cggattcgca
      481 gcgtagctga aaaggggctc tccctgggag gatctgacgg aggggcatcc attctggact
      541 tgcactcagg ggccctgtct gtcgggaagc actttgtgaa cctgtacaga tacttcgggg
      601 ataaaataca gaacatcttc tcagaggagg acttccggtt ataccgggag gtgcggcaga
      661 aggtccagct caccattgct gaggcttttg gcatcagcgc atcctcgctg catctgacca
      721 agcccacctt cttctcccgc ataaacagca cggaagcgcg gacggcgcac gacgagtact
      781 ggcatgcgca cgtggacaag gtgacctacg gctccttcga ctacacctcg ctgctgtacc
      841 tctccaacta cctggaggac ttcggcggag ggcggttcat gttcatggag gagggtgcca
      901 acaagacggt ggagccgaga gctggtcgcg tctccttctt cacctcgggg tccgagaacc
      961 tacaccgcgt ggagaaggtc cactggggca cccgttacgc catcaccatc gccttcagct
     1021 gcaaccccga ccatggcatc gaggacccag cgttcccgta gccagcagcc gggccaaggt
     1081 aacttcagga gggcccgtgt ggaggcagcc gcgccagtcg tgcacccacc cccacgtcca
     1141 cccgctcctg ttgcacagag tgccttagga attctctgat tttgatttgc tgacgtgtta
     1201 atcttttcat ctgtgagtaa atgaagggaa ccagcttttc acttctccag catcatgtgt
     1261 gcttgggctg taggcctggg agcctgaggt ggaggccagg aaagggaccc agcaggacgg
     1321 ggcacaagtc cccatctgtg aatggacggg actcatccac ccaggttcag caaccccccg
     1381 ggactcgtcc aggttcagca accccccggc ccatcaaaga ctggctaaag catcagccat
     1441 aaatggggac aaacgtgggg ccagcagctt ctgttcgggg tctcggcatc agcaaaccgc
     1501 agcagctttg gagaagggtc cgtgagtggc ggctctggag gcagcaacgg ggtcctttgg
     1561 ggtgggtggg agttctgctg gattcaggtg gaggtgaaca tctgccgttc ccacagccct
     1621 gcgtgcaccc ccaatgctgc tggcccacaa atcaccgtgg gccacggccc caccacacca
     1681 ggcttggccc tgtcagcggc cagcatccca agggccaggg tccgagtgtc ctcaccaagg
     1741 aggctcttgg cgtcgctgtg ccggctccca tgggccttct gctgggtcga gggtaggtct
     1801 cctcctcccc ctttgccctg gcattaaact gatggtcagg ctgggcgcgg tggctcacac
     1861 ctgtaatctc agcactgcgg gaggccgagg caggaggatc acttgaggtc aggagttcaa
     1921 gaccagcctg gccaacatgg cgaaaccctg tctctactaa aaacacaaaa acaaattaat
     1981 cccagctact ggggaggctg aggcaggaga atcgcttgaa cccagggggc agaagttgca
     2041 gtgagccgag atcgtgccac tacactccag cctgggtgac agagtgagac tccatcttaa
     2101 aaatataaaa ataaagtggt ggtcagagga gccccgaata gaccagttgt ggagaggcct
     2161 gggtggggtg gctggcaggg agggcaggcc aagcccagtt tctgcccaca gtcacctcga
     2221 ggtgactgtc cagggctttg ggcaccttcc cgggaggggg acggccgccc accctgagtg
     2281 gtgttggaag ctgggctctc ctggatgccc tgacccagct gcctggggag agccctgggc
     2341 ccctcctccc tcagcacctc ctccctcagc ccctcctgcc tcggtccctc ctcccttagc
     2401 ctgtctggca tagatccatg ttccctagcc cctggcacag gtgcctctga ctggaggagg
     2461 ccccacctgt ggcccgggag ctgctctggg ggttgataaa gggcagcatt attgggtcct
     2521 gggaaggagc gggcgtgagg ccagctgagg catggtgacc cctgggaagg agcgggcgtg
     2581 aggccagctg aggcatggtg acccctggga aggagcgggc gtgaggccag ctgaggcatg
     2641 gtgacccctg ggaaggagcg ggcgtgaggc cagctgaggc atggtgaccc ctgggaagga
     2701 gcgggcgtga ggccagctga ggcatggtga cccctgggta cgggggactt gggggccgca
     2761 ccttggtttg cccagggccc ctcctgcacc acgggccaca tgcggaggac ggcgtgggat
     2821 aggctccctg ggtccacagc ttctgcccgt gtatggggaa ccctccttgg tcagggctgc
     2881 aggctctggg cagatggggc aggaaccctg aggctcccgc gccctcccat ggcctctgat
     2941 gtgggacact ggagcgaggc acgattctga aggactccat ggatctggga ggatgaggcc
     3001 cacctccggt tggtggccaa agccgtcctt gcggggccgg ctgcttcacg gacactctcc
     3061 gggtcgggct ggtgggcccc atcgtgggtg ggaagtcgcc tgagcctggg ccgcccttga
     3121 gcttctccca gtcttgactt tccagagggt ccgtggctgt ggtcatggtc ggggcaggtg
     3181 gaaaatgctg catggaaacc tgatcctgtc accttggagt aaatgatgat gtcgccggct
     3241 tctcgccacg tctaaaggat aaatgcattt gaagaaagtg ggtgttgggt ttgttatggg
     3301 ttaaagtgct tttgaaataa gtaaattatt agtttgattt tcattcttgg ctacttacac
     3361 tattcatgat aatcacagag atacttggac aaagaaatat atttgggcaa aagcaagaat
     3421 ttccttcttt ttttttttga gacggagtct aactctgtcg cccaggctgg agtgcagtgg
     3481 cgcaatctcg gctcactgca aggtccacct cctgggttcc caccattctc ctgcctcaac
     3541 ctcccgagta gctgggacta caggcgcccg ccaccatgcc cggctaattt tttttgtatt
     3601 tttagtagag atgggatttc accgtgttag ccagaatgaa gaatttcctt ctgaagtggg
     3661 aacatatggc tcatgctggt aatcccagca ctttgggagg ccaaggtagg aagatcactt
     3721 gagcccagga gttggagacc catctgtgca acatagtgag acgctgtctg tacaagaaac
     3781 ttttaaaaaa tgtagctggg cgtggcagtg tgctcctgtg gtcccagcta ctcggagctg
     3841 aggcaggacg actgcttgag cccaggaggt cgaggctaca gtgagctgtg acggctccac
     3901 tgcattccag cctgggagac agcaagatac tgtctcaaaa aaaaatttat cattgaagcc
     3961 tgggcatttt aaaaaaataa aaaggtggga aaatacgtgg gcacagcagt gaatcctcac
     4021 accctgggct ttgcccaaga agtgctcgtg aacctgatga aagtgtcggg tgtggccgac
     4081 gtgaggctgt tccaggagcc acgaggggtg attggttccg ctagaaggtt ccagggagga
     4141 actggagtct caggtgtgtc ctctgatgag tgatctattt ttaagtaaaa gtgtttcatt
     4201 aaagtcaaag atgattattc ctttcaaaat aaagaatcta ggagggcga
//
