LOCUS       NM_001386125           27019 bp    mRNA    linear   PRI 12-OCT-2024
DEFINITION  Homo sapiens obscurin, cytoskeletal calmodulin and
            titin-interacting RhoGEF (OBSCN), transcript variant 3, mRNA.
ACCESSION   NM_001386125
VERSION     NM_001386125.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 27019)
  AUTHORS   Wang,L., Tsakiroglou,P., Gonzales,R., Cho,S., Li,A., Dos
            Remedios,C., Wright,N. and Kontrogianni-Konstantopoulos,A.
  TITLE     Essential role of obscurin kinase-1 in cardiomyocyte coupling via
            N-cadherin phosphorylation
  JOURNAL   JCI Insight 9 (3), e162178 (2024)
   PUBMED   38127465
  REMARK    GeneRIF: Essential role of obscurin kinase-1 in cardiomyocyte
            coupling via N-cadherin phosphorylation.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27019)
  AUTHORS   Zemorshidi,F., Topf,A., Claeys,K.G., McFarlane,A., Patton,A.,
            Nafissi,S. and Straub,V.
  TITLE     Novel OBSCN variants associated with a risk to exercise-intolerance
            and rhabdomyolysis
  JOURNAL   Neuromuscul Disord 34, 83-88 (2024)
   PUBMED   38159459
  REMARK    GeneRIF: Novel OBSCN variants associated with a risk to
            exercise-intolerance and rhabdomyolysis.
REFERENCE   3  (bases 1 to 27019)
  AUTHORS   Cabrera-Serrano,M., Caccavelli,L., Savarese,M., Vihola,A.,
            Jokela,M., Johari,M., Capiod,T., Madrange,M., Bugiardini,E.,
            Brady,S., Quinlivan,R., Merve,A., Scalco,R., Hilton-Jones,D.,
            Houlden,H., Aydin,H.I., Ceylaner,S., Drewes,S., Vockley,J.,
            Taylor,R.L., Folland,C., Kelly,A., Goullee,H., Ylikallio,E.,
            Auranen,M., Tyynismaa,H., Udd,B., Forrest,A.R.R., Davis,M.R.,
            Bratkovic,D., Manton,N., Robertson,T., O'Gorman,C., McCombe,P.,
            Laing,N.G., Phillips,L., de Lonlay,P. and Ravenscroft,G.
  TITLE     Bi-allelic loss-of-function OBSCN variants predispose individuals
            to severe recurrent rhabdomyolysis
  JOURNAL   Brain 145 (11), 3985-3998 (2022)
   PUBMED   34957489
  REMARK    GeneRIF: Bi-allelic loss-of-function OBSCN variants predispose
            individuals to severe recurrent rhabdomyolysis.
REFERENCE   4  (bases 1 to 27019)
  AUTHORS   Tuntithavornwat,S., Shea,D.J., Wong,B.S., Guardia,T., Lee,S.J.,
            Yankaskas,C.L., Zheng,L., Kontrogianni-Konstantopoulos,A. and
            Konstantopoulos,K.
  TITLE     Giant obscurin regulates migration and metastasis via
            RhoA-dependent cytoskeletal remodeling in pancreatic cancer
  JOURNAL   Cancer Lett 526, 155-167 (2022)
   PUBMED   34826548
  REMARK    GeneRIF: Giant obscurin regulates migration and metastasis via
            RhoA-dependent cytoskeletal remodeling in pancreatic cancer.
REFERENCE   5  (bases 1 to 27019)
  AUTHORS   Fukuzawa,A., Idowu,S. and Gautel,M.
  TITLE     Complete human gene structure of obscurin: implications for isoform
            generation by differential splicing
  JOURNAL   J Muscle Res Cell Motil 26 (6-8), 427-434 (2005)
   PUBMED   16625316
  REMARK    GeneRIF: The complete gene giant muscle protein obscurin was
            analysed. The fusion of the conventional obscurin A, containing
            only the GEF domain, and obscurin B, fusing into the 3' kinase
            exons, was experimentally confirmed and analysed.
REFERENCE   6  (bases 1 to 27019)
  AUTHORS   Russell,M.W., Raeker,M.O., Korytkowski,K.A. and Sonneman,K.J.
  TITLE     Identification, tissue expression and chromosomal localization of
            human Obscurin-MLCK, a member of the titin and Dbl families of
            myosin light chain kinases
  JOURNAL   Gene 282 (1-2), 237-246 (2002)
   PUBMED   11814696
REFERENCE   7  (bases 1 to 27019)
  AUTHORS   Harrington,A.W., Kim,J.Y. and Yoon,S.O.
  TITLE     Activation of Rac GTPase by p75 is necessary for c-jun N-terminal
            kinase-mediated apoptosis
  JOURNAL   J Neurosci 22 (1), 156-166 (2002)
   PUBMED   11756498
REFERENCE   8  (bases 1 to 27019)
  AUTHORS   Bang,M.L., Centner,T., Fornoff,F., Geach,A.J., Gotthardt,M.,
            McNabb,M., Witt,C.C., Labeit,D., Gregorio,C.C., Granzier,H. and
            Labeit,S.
  TITLE     The complete gene sequence of titin, expression of an unusual
            approximately 700-kDa titin isoform, and its interaction with
            obscurin identify a novel Z-line to I-band linking system
  JOURNAL   Circ Res 89 (11), 1065-1072 (2001)
   PUBMED   11717165
REFERENCE   9  (bases 1 to 27019)
  AUTHORS   Young,P., Ehler,E. and Gautel,M.
  TITLE     Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor
            protein involved in sarcomere assembly
  JOURNAL   J Cell Biol 154 (1), 123-136 (2001)
   PUBMED   11448995
REFERENCE   10 (bases 1 to 27019)
  AUTHORS   Cirino,A.L. and Ho,C.
  TITLE     Hypertrophic Cardiomyopathy Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301725
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL359510.24, AL353593.33 and
            AL670729.19.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: The obscurin gene spans more than 150 kb, contains over 80
            exons and encodes a protein of approximately 720 kDa. The encoded
            protein contains 68 Ig domains, 2 fibronectin domains, 1
            calcium/calmodulin-binding domain, 1 RhoGEF domain with an
            associated PH domain, and 2 serine-threonine kinase domains. This
            protein belongs to the family of giant sacromeric signaling
            proteins that includes titin and nebulin, and may have a role in
            the organization of myofibrils during assembly and may mediate
            interactions between the sarcoplasmic reticulum and myofibrils.
            Alternatively spliced transcript variants encoding different
            isoforms have been identified. [provided by RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000680850.1/ ENSP00000505517.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-142               AL359510.24        89116-89257
            143-1148            AL359510.24        92838-93843
            1149-1418           AL359510.24        94513-94782
            1419-1679           AL359510.24        95246-95506
            1680-1988           AL353593.33        2117-2425
            1989-2255           AL353593.33        2890-3156
            2256-2537           AL353593.33        3748-4029
            2538-2813           AL353593.33        4340-4615
            2814-3089           AL353593.33        6651-6926
            3090-3365           AL353593.33        11786-12061
            3366-3641           AL353593.33        30510-30785
            3642-3917           AL353593.33        31623-31898
            3918-4193           AL353593.33        32740-33015
            4194-4469           AL353593.33        33855-34130
            4470-4745           AL353593.33        37292-37567
            4746-5021           AL353593.33        43978-44253
            5022-5297           AL353593.33        46828-47103
            5298-5573           AL353593.33        51443-51718
            5574-5849           AL353593.33        55857-56132
            5850-6146           AL353593.33        59252-59548
            6147-6422           AL353593.33        60599-60874
            6423-6701           AL353593.33        61097-61375
            6702-6968           AL353593.33        61505-61771
            6969-7238           AL353593.33        61899-62168
            7239-7505           AL353593.33        63087-63353
            7506-7772           AL353593.33        63777-64043
            7773-7885           AL353593.33        64257-64369
            7886-8039           AL353593.33        64487-64640
            8040-8201           AL353593.33        64832-64993
            8202-8306           AL353593.33        65081-65185
            8307-8573           AL353593.33        66016-66282
            8574-8843           AL353593.33        66502-66771
            8844-9110           AL353593.33        67148-67414
            9111-9377           AL353593.33        67506-67772
            9378-9644           AL353593.33        67857-68123
            9645-9917           AL353593.33        69260-69532
            9918-10184          AL353593.33        70345-70611
            10185-10451         AL353593.33        70830-71096
            10452-10724         AL353593.33        73405-73677
            10725-10991         AL353593.33        74100-74366
            10992-11258         AL353593.33        75021-75287
            11259-11522         AL353593.33        75388-75651
            11523-11786         AL353593.33        75952-76215
            11787-12050         AL353593.33        79225-79488
            12051-12314         AL353593.33        79850-80113
            12315-12578         AL353593.33        80680-80943
            12579-12842         AL353593.33        81479-81742
            12843-13106         AL353593.33        82107-82370
            13107-13370         AL353593.33        85781-86044
            13371-13634         AL353593.33        86586-86849
            13635-13898         AL353593.33        87209-87472
            13899-14162         AL353593.33        91002-91265
            14163-14426         AL353593.33        91630-91893
            14427-14690         AL353593.33        92450-92713
            14691-14957         AL353593.33        93699-93965
            14958-15224         AL353593.33        94228-94494
            15225-15497         AL353593.33        94586-94858
            15498-15770         AL353593.33        95438-95710
            15771-15967         AL353593.33        96426-96622
            15968-16043         AL353593.33        96811-96886
            16044-16316         AL353593.33        103174-103446
            16317-16592         AL353593.33        104036-104311
            16593-16880         AL353593.33        104791-105078
            16881-17162         AL353593.33        105219-105500
            17163-17533         AL353593.33        106211-106581
            17534-18404         AL353593.33        108671-109541
            18405-18683         AL353593.33        110655-110933
            18684-18762         AL353593.33        120187-120265
            18763-18887         AL353593.33        120526-120650
            18888-19085         AL353593.33        120910-121107
            19086-19118         AL353593.33        121839-121871
            19119-19217         AL353593.33        122142-122240
            19218-19436         AL353593.33        122407-122625
            19437-19497         AL353593.33        123118-123178
            19498-19568         AL353593.33        123527-123597
            19569-19691         AL353593.33        124331-124453
            19692-19831         AL353593.33        124571-124710
            19832-20032         AL353593.33        125271-125471
            20033-20115         AL353593.33        125617-125699
            20116-20289         AL353593.33        126180-126353
            20290-20446         AL353593.33        127272-127428
            20447-20563         AL353593.33        127833-127949
            20564-20728         AL353593.33        128051-128215
            20729-20887         AL353593.33        128422-128580
            20888-21065         AL353593.33        128764-128941
            21066-21179         AL353593.33        129446-129559
            21180-21347         AL670729.19        3253-3420
            21348-21450         AL670729.19        4204-4306
            21451-21580         AL670729.19        4684-4813
            21581-21692         AL670729.19        6314-6425
            21693-21872         AL670729.19        15939-16118
            21873-21969         AL670729.19        18344-18440
            21970-22094         AL670729.19        18799-18923
            22095-22207         AL670729.19        19437-19549
            22208-22376         AL670729.19        19763-19931
            22377-22458         AL670729.19        20171-20252
            22459-22659         AL670729.19        20338-20538
            22660-22720         AL670729.19        21249-21309
            22721-22798         AL670729.19        21702-21779
            22799-22971         AL670729.19        22085-22257
            22972-22998         AL670729.19        22499-22525
            22999-23151         AL670729.19        23305-23457
            23152-23197         AL670729.19        23556-23601
            23198-23275         AL670729.19        24042-24119
            23276-25334         AL670729.19        24386-26444
            25335-25415         AL670729.19        27295-27375
            25416-25526         AL670729.19        27677-27787
            25527-25694         AL670729.19        27948-28115
            25695-25817         AL670729.19        29065-29187
            25818-25988         AL670729.19        29371-29541
            25989-26070         AL670729.19        30156-30237
            26071-26310         AL670729.19        30415-30654
            26311-26534         AL670729.19        30852-31075
            26535-26610         AL670729.19        31294-31369
            26611-26760         AL670729.19        31634-31783
            26761-27019         AL670729.19        31981-32239
FEATURES             Location/Qualifiers
     source          1..27019
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q42.13"
     gene            1..27019
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /note="obscurin, cytoskeletal calmodulin and
                     titin-interacting RhoGEF"
                     /db_xref="GeneID:84033"
                     /db_xref="HGNC:HGNC:15719"
                     /db_xref="MIM:608616"
     exon            1..142
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            143..1148
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     CDS             161..26938
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /EC_number="2.7.11.1"
                     /note="isoform c is encoded by transcript variant 3;
                     obscurin, myosin light chain kinase; obscurin-MLCK"
                     /codon_start=1
                     /product="obscurin isoform c"
                     /protein_id="NP_001373054.1"
                     /db_xref="CCDS:CCDS91171.1"
                     /db_xref="GeneID:84033"
                     /db_xref="HGNC:HGNC:15719"
                     /db_xref="MIM:608616"
                     /translation="MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWE
                     KDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAE
                     AACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRV
                     EELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAA
                     LLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQ
                     LVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVP
                     FKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVR
                     NVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVELAVPVGP
                     VHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAP
                     RKPPLQPPVDPVVKARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGTYTWIRCHEA
                     EWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRTPLKAVQA
                     VEGGEVTFSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGAQL
                     KFVANGIESSIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAELSDQAAAVTWL
                     KDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARFL
                     HKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLV
                     AATVTRQDEGTYSCRVGEDSVDFRLRVSEPKAVFAKEQPACREVQAEVGASATLSCEV
                     AQDQMEVTWYKDGKKLSSSSKVHVEAVGCMRRLVVQQVGQADSGEYSCEARGQRVSFR
                     LDVAEPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCM
                     EATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEA
                     GASATLSCEVAQAQTEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSC
                     EARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVTWYKDGK
                     KLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQ
                     SVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQV
                     GKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQ
                     TEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEAGGQRLSFHLDVS
                     EPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVG
                     CTRRLVVQQACQADTGEYSCEAGGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGAST
                     TLSCEVAQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEAGS
                     QRLSFHLHVAEPKAVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSS
                     SLKVHVEAAGCTRRLVVQQAGQADTGEYSCEAGGQQLSFRLQVAEPKAVFAKEQPASR
                     EVQAEAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQAD
                     AGEYSCKAGDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVT
                     WYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEAGGQQLSFRLQVAEPKA
                     VFAKEQVVFAKDQPVHREVQAEAGTSTMLSCEVAQAQTEVMWYKDGKKLSSSSKMRVE
                     AVGCTRRLVVQEAGQADAGEYSCEAGGQRLSFHLHVAEPKVVFAKEQPACREVQAEAG
                     ASATLSCEVAQGQMEVTWYKDGKKLSSSSKVHMEASGYTRRLVVQQAGQADAGEYSCE
                     AGGQRLSFRLHVAELEPQISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGV
                     EIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVAAKFCRLL
                     EPVCGELGGTVTLACELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAE
                     DAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDVAVVW
                     FRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVREAPVL
                     FKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGARHRLVLH
                     NVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQLSHADV
                     DGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVTE
                     LPVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRS
                     LTIYRCEFADQGVYVCDAHDAQSSASVKVQGRNIQIVRPLEDVEVMEKDGATFSCEVS
                     HDEVPGQWFWEGSKLRPTDNVRIRQEGRTYTLIYRRVLAEDAGEIQFVAENAESRAQL
                     RVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQELQPGPKYELVSDG
                     LYRKLIISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFE
                     CETSIPSVRPPKWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSR
                     SSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFK
                     MSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVEAREVTVTGPLQDAEATEEG
                     WASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRASS
                     LKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPS
                     DKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEV
                     LEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAG
                     EVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTPVHWLKDR
                     KAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVEASKSTASLHVEEKANCFTEE
                     LTNLQVEEKGTAVFTCKTEHPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEK
                     ADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVH
                     WFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRASAALRVTEKP
                     SVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLL
                     ITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKDLEVLEGGAATLRCVLSSV
                     AAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSCSFGDQTTSATLTV
                     TALPAQFIGKLRNKEATEGATATLRCELSKAAPVEWRKGSETLRDGDRYCLRQDGAMC
                     ELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPAHFIGRLRHQESIEGATATLRCEL
                     SKAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATL
                     TVKALPAKFTEGLRNEEAVEGATAMLWCELSKVAPVEWRKGPENLRDGDRYILRQEGT
                     RCELQICGLAMADAGEYLCVCGQERTSATLTIRALPARFIEDVKNQEAREGATAVLQC
                     ELNSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSA
                     MLTVRALPIKFTEGLRNEEATEGATAVLRCELSKMAPVEWWKGHETLRDGDRHSLRQD
                     GARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRAMPSKFIEGLRNEEATEGDTATL
                     WCELSKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVCGQERT
                     SATLTVRALPARFIEDVKNQEAREGATAVLQCELSKAAPVEWRKGSETLRGGDRYSLR
                     QDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRALPARFTQDLKTKEASEGATA
                     TLQCELSKVAPVEWKKGPETLRDGGRYSLKQDGTRCELQIHDLSVADAGEYSCMCGQE
                     RTSATLTVRALPARFTEGLRNEEAMEGATATLQCELSKAAPVEWRKGLEALRDGDKYS
                     LRQDGAVCELQIHGLAMADNGVYSCVCGQERTSATLTVRALPARFIEDMRNQKATEGA
                     TVTLQCKLRKAAPVEWRKGPNTLKDGDRYSLKQDGTSCELQIRGLVIADAGEYSCICE
                     QERTSATLTVRALPARFIEDVRNHEATEGATAVLQCELSKAAPVEWRKGSETLRDGDR
                     YSLRQDGTRCELQIRGLAVEDTGEYLCVCGQERTSATLTVRALPARFIDNMTNQEARE
                     GATATLHCELSKVAPVEWRKGPETLRDGDRHSLRQDGTRCELQIRGLSVADAGEYSCV
                     CGQERTSATLTIRALPAKFTKGLRNEEATEGATAMLQCELSKVAPVEWRKGPETLRDG
                     DRYNLRQDGTRCELQIHGLSVADTGEYSCVCGQEKTSATLTVKAPQPVFREPLQSLQA
                     EEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEY
                     TCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGASVEWRKGSLQ
                     LFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKFKTRLQ
                     SLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEA
                     KDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQ
                     WCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPE
                     VTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHL
                     LTLHKVTLEDAGTVSFHVGTCSSEAQLKVTAKNTVVRGLENVEALEGGEALFECQLSQ
                     PEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDMVTSA
                     FLTVRGWRLEILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWT
                     VTADGSHHALLLRSAQPHHAGEVTFACRDAVASARLTVLGLPDPPEDAEVVARSSHTV
                     TLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFRVA
                     AVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGEDVSLELEVVAEAGEVI
                     WHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHCGLAQGSICPAAATFQVAL
                     SPASVDEAPQPSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSISELPEEDGRSQRL
                     PQEAEEVAPDLSEGYSTADELARTGDADLSHTSSDDESRAGTPSLVTYLKKAGRPGTS
                     PLASKVGAPAAPSVKPQQQQEPLAAVRPPLGDLSTKDLGDPSMDKAAVKIQAAFKGYK
                     VRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHH
                     IDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGEL
                     DDAFRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAEPEEPADWQTYREDEHFICIR
                     FEALTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCISKETPAPVVPPEPLPSL
                     LTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINED
                     QQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSY
                     FSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLY
                     WFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVR
                     GPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEA
                     ERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVS
                     GLPKVEEQEKVKEALISTFLQGTTQAISAQGLETASFADLGGQRKEEPLAAKEALGHL
                     SLAEVGTEEFLQKLTSQITEMVSAKITQAKLQVPGGDSDEDSKTPSASPRHGRSRPSS
                     SIQESSSESEDGDARGEIFDIYVVTADYLPLGAEQDAITLREGQYVEVLDAAHPLRWL
                     VRTKPTKSSPSRQGWVSPAYLDRRLKLSPEWGAAEAPEFPGEAVSEDEYKARLSSVIQ
                     ELLSSEQAFVEELQFLQSHHLQHLERCPHVPIAVAGQKAVIFRNVRDIGRFHSSFLQE
                     LQQCDTDDDVAMCFIKNQAAFEQYLEFLVGRVQAESVVVSTAIQEFYKKYAEEALLAG
                     DPSQPPPPPLQHYLEQPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQR
                     AENKLHVSLMENYPGTLQALGEPIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNHLVI
                     CKPRRDSRTDTVSYVFRNMMKLSSIDLNDQVEGDDRAFEVWQEREDSVRKYLLQARTA
                     IIKSSWVKEICGIQQRLALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISW
                     YKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ
                     VPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSG
                     LLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVED
                     TTLERADQEVTSVLKRLLGPKAPGPSTGDLTGPGPCPRGAPALQETGSQPPVTGTSEA
                     PAVPPRVPQPLLHEGPEQEPEAIARAQEWTVPIRMEGAAWPGAGTGELLWDVHSHVVR
                     ETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSV
                     QLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEP
                     DSEKQSHRRKLHSFYEVKEEIGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQAYR
                     ERDILAALSHPLVTGLLDQFETRKTLILILELCSSEELLDRLYRKGVVTEAEVKVYIQ
                     QLVEGLHYLHSHGVLHLDIKPSNILMVHPAREDIKICDFGFAQNITPAELQFSQYGSP
                     EFVSPEIIQQNPVSEASDIWAMGVISYLSLTCSSPFAGESDRATLLNVLEGRVSWSSP
                     MAAHLSEDAKDFIKATLQRAPQARPSAAQCLSHPWFLKSMPAEEAHFINTKQLKFLLA
                     RSRWQRSLMSYKSILVMRSIPELLRGPPDSPSLGVARHLCRDTGGSSSSSSSSDNELA
                     PFARAKSLPPSPVTHSPLLHPRGFLRPSASLPEEAEASERSTEAPAPPASPEGAGPPA
                     AQGCVPRHSVIRSLFYHQAGESPEHGALAPGSRRHPARRRHLLKGGYIAGALPGLREP
                     LMEHRVLEEEAAREEQATLLAKAPSFETALRLPASGTHLAPGHSHSLEHDSPSTPRPS
                     SEACGEAQRLPSAPSGGAPIRDMGHPQGSKQLPSTGGHPGTAQPERPSPDSPWGQPAP
                     FCHPKQGSAPQEGCSPHPAVAPCPPGSFPPGSCKEAPLVPSSPFLGQPQAPPAPAKAS
                     PPLDSKMGPGDISLPGRPKPGPCSSPGSASQASSSQVSSLRVGSSQVGTEPGPSLDAE
                     GWTQEAEDLSDSTPTLQRPQEQATMRKFSLGGRGGYAGVAGYGTFAFGGDAGGMLGQG
                     PMWARIAWAVSQSEEEEQEEARAESQSEEQQEARAESPLPQVSARPVPEVGRAPTRSS
                     PEPTPWEDIGQVSLVQIRDLSGDAEAADTISLDISEVDPAYLNLSDLYDIKYLPFEFM
                     IFRKVPKSAQPEPPSPMAEEELAEFPEPTWPWPGELGPHAGLEITEESEDVDALLAEA
                     AVGRKRKWSSPSRSLFHFPGRHLPLDEPAELGLRERVKASVEHISRILKGRPEGLEKE
                     GPPRKKPGLASFRLSGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWS
                     KDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAE
                     RPSSSPCPDIGEVYADGVLLVWKPVESYGPVTYIVQCSLEGGSWTTLASDIFDCCYLT
                     SKLSRGGTYTFRTACVSKAGMGPYSSPSEQVLLGGPSHLASEEESQGRSAQPLPSTKT
                     FAFQTQIQRGRFSVVRQCWEKASGRALAAKIIPYHPKDKTAVLREYEALKGLRHPHLA
                     QLHAAYLSPRHLVLILELCSGPELLPCLAERASYSESEVKDYLWQMLSATQYLHNQHI
                     LHLDLRSENMIITEYNLLKVVDLGNAQSLSQEKVLPSDKFKDYLETMAPELLEGQGAV
                     PQTDIWAIGVTAFIMLSAEYPVSSEGARDLQRGLRKGLVRLSRCYAGLSGGAVAFLRS
                     TLCAQPWGRPCASSCLQCPWLTEEGPACSRPAPVTFPTARLRVFVRNREKRRALLYKR
                     HNLAQVR"
     exon            1149..1418
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            1419..1679
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            1680..1988
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            1989..2255
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            2256..2537
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            2538..2813
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            2814..3089
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            3090..3365
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            3366..3641
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            3642..3917
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            3918..4193
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            4194..4469
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            4470..4745
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            4746..5021
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            5022..5297
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            5298..5573
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            5574..5849
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            5850..6146
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            6147..6422
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            6423..6701
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            6702..6968
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            6969..7238
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            7239..7505
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            7506..7772
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            7773..7885
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            7886..8039
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            8040..8201
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            8202..8306
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            8307..8573
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            8574..8843
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            8844..9110
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            9111..9377
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            9378..9644
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            9645..9917
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            9918..10184
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            10185..10451
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            10452..10724
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            10725..10991
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            10992..11258
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            11259..11522
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            11523..11786
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            11787..12050
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            12051..12314
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            12315..12578
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            12579..12842
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            12843..13106
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            13107..13370
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            13371..13634
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            13635..13898
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            13899..14162
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            14163..14426
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            14427..14690
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            14691..14957
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            14958..15224
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            15225..15497
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            15498..15770
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            15771..15967
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            15968..16043
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            16044..16316
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            16317..16592
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            16593..16880
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            16881..17162
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            17163..17533
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            17534..18404
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            18405..18683
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            18684..18762
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            18763..18887
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            18888..19085
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            19086..19118
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            19119..19217
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            19218..19436
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            19437..19497
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            19498..19568
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            19569..19691
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            19692..19831
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            19832..20032
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            20033..20115
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            20116..20289
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            20290..20446
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            20447..20563
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            20564..20728
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            20729..20887
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            20888..21065
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            21066..21179
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            21180..21347
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            21348..21450
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            21451..21580
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            21581..21692
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            21693..21872
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            21873..21969
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            21970..22094
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            22095..22207
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            22208..22376
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            22377..22458
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            22459..22659
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            22660..22720
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            22721..22798
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            22799..22971
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            22972..22998
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            22999..23151
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            23152..23197
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            23198..23275
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            23276..25334
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            25335..25415
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            25416..25526
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            25527..25694
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            25695..25817
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            25818..25988
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            25989..26070
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            26071..26310
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            26311..26534
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            26535..26610
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            26611..26760
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            26761..27019
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /inference="alignment:Splign:2.1.0"
     regulatory      26994..26999
                     /regulatory_class="polyA_signal_sequence"
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /note="hexamer: AATAAA"
     polyA_site      27019
                     /gene="OBSCN"
                     /gene_synonym="ARHGEF30; RHABDO1; UNC89"
                     /note="major polyA site"
ORIGIN      
        1 agtttgagga gcggccggag tgtgggctgc tggtaggcag cctgctggtc ctgggccctc
       61 ggagggaggt gagacccggc agcccctgcc tcccagcctg tgcccccagc ctgcgtgctg
      121 cccagagccc ccatagagag aggtccccgc cgccaccctc atggatcagc cacagttcag
      181 cggggcgccc cgctttctca cccggcccaa ggccttcgtg gtgtcggtgg gcaaggacgc
      241 caccctcagc tgccagatcg tgggtaatcc cacgccacag gtgagctggg agaaggacca
      301 gcagccggtg gcggccggcg cgcgcttccg tctggcccag gacggcgacc tctaccgcct
      361 cactatcctg gacctggcgc tgggcgacag tgggcaatac gtgtgccgcg cgcgcaatgc
      421 cataggcgag gccttcgctg ctgtgggcct gcaggtggac gcggaggccg cgtgcgccga
      481 gcaggcgccg cacttcctgc tgcggcccac gtccatccgc gtgcgcgagg gctcagaggc
      541 caccttccgc tgccgcgtgg gtggctcccc gaggccggca gtgagctggt ccaaggacgg
      601 gcggcgcctg ggtgagcccg acggcccccg cgtgcgcgtg gaggagctcg gcgaggcaag
      661 tgcgctgcgc attcgggcgg cgcggccgcg cgacggcggc acttacgagg tccgcgccga
      721 gaacccgctg ggcgctgcca gcgccgccgc ggcgctagtg gtggactcgg acgccgcgga
      781 cacggccagc cggcccggga cctccacggc cgcgctcctg gcgcacctgc agcggcggcg
      841 cgaggctatg cgcgccgagg gcgcccccgc ctcaccgccc agcaccggca cgcgcacctg
      901 cacggtgact gaaggcaagc acgcgcgcct cagctgctac gtgaccggcg agcccaagcc
      961 cgagacggtg tggaagaagg acggccagct ggtgaccgag ggccggcgcc acgtggtgta
     1021 cgaggacgcg caggagaact tcgtgctcaa gatcctcttc tgcaagcagt cggaccgcgg
     1081 cctctacacc tgcacggcgt ccaacctcgt gggccagacc tacagctctg tgctggtcgt
     1141 agtgcgcgag cccgcggttc ccttcaaaaa gcggctgcaa gatctggagg tgcgggagaa
     1201 ggagtcggcc acgttcctat gtgaggtgcc ccagccgtcc actgaggccg cgtggttcaa
     1261 ggaggagacg cggttgtggg cgagcgccaa gtacggcatc gaggaggagg gcaccgagcg
     1321 ccgcctgacc gtgcgcaatg tctcggccga cgacgacgcg gtgtacatct gcgagacgcc
     1381 agagggcagc cgcacggtgg cggagctcgc agtccaagga aacctcctcc gaaagctccc
     1441 tcggaagacg gcggtgcgcg tgggcgacac ggctatgttt tgcgtggagc tggcggtccc
     1501 ggtgggcccc gtccactggc tgcggaacca ggaggaagtg gtggcggggg gccgcgtggc
     1561 catctccgcg gagggcacgc gccacacact aaccatctcc cagtgctgcc tggaggatgt
     1621 gggccaggtg gcctttatgg ctggcgactg ccagacgtcc acccagttct gcgtgtcggc
     1681 ccccaggaag cctcccctgc aaccccctgt ggatcctgtg gtaaaggcca ggatggagag
     1741 ttccgtgatt ctcagctggt ccccaccacc ccatggggaa cgccctgtca ctatcgacgg
     1801 ctacctggta gagaagaaga agcttggcac ctacacctgg atcaggtgcc acgaggctga
     1861 atgggtggct acacctgagc tgaccgtggc tgatgtggcg gaggagggga acttccagtt
     1921 ccgagtgtcc gctctcaaca gctttggtca gagtccctac ctcgagttcc cggggactgt
     1981 ccacctggcc cccaagctgg ccgtgaggac accgctgaag gcggtgcagg cggtagaggg
     2041 tggcgaggtc actttctccg tggacctcac ggtggcctca gcgggtgagt ggttcctgga
     2101 tgggcaggcc ctgaaggcca gcagtgtgta tgagatccac tgtgatcgca cccggcacac
     2161 gctcaccatc cgggaggtgc ccgccagcct gcacggggcg cagctgaagt tcgtggccaa
     2221 cggcattgag agcagcatcc ggatggaggt ccgggcggcc ccagggctga ctgccaacaa
     2281 gccgccagcc gcagctgccc gggaggtgct ggctcggctg cacgaggagg cgcagctgct
     2341 ggctgagctg tcagatcagg ctgcggctgt gacgtggctg aaggatggtc gcacactgtc
     2401 cccaggcccc aagtatgagg tgcaggcatc ggccgggcgg cgggtgctcc ttgtgcgaga
     2461 tgtggcccgg gacgatgcag gcctctacga gtgcgtcagc cgcgggggcc gcatcgccta
     2521 ccagctctcc gtgcaaggcc tcgcgcgctt tctgcacaag gacatggcgg gcagctgtgt
     2581 ggatgccgtg gctgggggcc cggcgcagtt tgagtgtgag acctccgaag cccacgtcca
     2641 cgtgcactgg tacaaggatg gcatggagct gggccactcc ggtgagcgct tcttgcagga
     2701 ggatgtgggg acgcggcacc ggctggtggc agccacagtc accaggcagg atgaaggcac
     2761 ctactcctgc cgcgtgggcg aggactctgt ggacttccgg ctccgcgtct ctgagcccaa
     2821 ggcggtgttt gccaaggagc agccggcgtg cagggaggtg caggctgagg tgggggccag
     2881 cgccacgctg agctgtgagg tggcccagga ccagatggag gtgacgtggt acaaggacgg
     2941 gaagaagttg agctccagct cgaaagtgca cgtggaggct gtgggctgta tgcggaggct
     3001 ggtggtgcag caggtgggcc aggcagactc cggagagtac agctgtgagg ccaggggaca
     3061 gagggtctcc ttccgcctgg acgttgcaga gcccaaggtg gtgtttgcta aggagcagct
     3121 ggcacgcagg aagctgcagg cagaggcagg agccagtgcc acactgagct gcgaggtggc
     3181 ccaggcccag acggaggtga cgtggtacaa ggatgggaag aagctgagct ccagctcgaa
     3241 agtgtgcatg gaggccacag gctgcacgcg caggctggtt gtgcagcagg caggccaggc
     3301 ggatgccggg gagtatagct gcgaggctgg gggccagcgg ctctccttcc atctggatgt
     3361 caaagagccc aaggtggtgt ttgccaagga ccaggtggca cacagtgagg tgcaggctga
     3421 ggcaggggcc agtgccacgc tgagctgcga ggtggcccag gcccagacgg aggtgatgtg
     3481 gtacaaagat gggaagaagc tgagctccag cttgaaagtg catgtagagg ccaagggctg
     3541 cagacggagg ctggtggtgc agcaggcagg caagacagat gccggggact acagctgcga
     3601 ggccaggggc cagagggtct ccttccgcct gcacatcaca gagcccaaga tgatgtttgc
     3661 aaaggagcag tcagtgcata atgaggtgca ggctgaggcg ggggccagtg ccatgctgag
     3721 ctgtgaggtg gcccaggccc agacggaggt gacgtggtac aaggatggga agaagctgag
     3781 ctccagctca aaagtgggca tggaggtcaa agggtgcaca cggaggctgg tgctgccaca
     3841 ggcgggcaaa gcagatgctg gggagtacag ctgtgaggct gggggccaga gagtctcctt
     3901 ccacctgcac atcacagagc ccaagggggt gtttgcgaag gagcagtcag tgcataatga
     3961 ggtgcaggct gaggcgggga ccactgccat gctgagctgt gaggtggccc agccccagac
     4021 agaggtgacg tggtacaagg acgggaagaa gctgagctcc agctcaaaag tacgcatgga
     4081 ggtcaagggc tgcacacgaa ggctggtagt gcagcaggtg ggcaaagcag atgctgggga
     4141 gtacagctgc gaggctgggg gccagagagt ctcctttcaa ctgcacatca cagagcccaa
     4201 ggcagtgttt gccaaggagc agttggtgca taatgaggtg cggactgagg caggggccag
     4261 tgccacactg agctgtgagg tggcccaggc ccagacagag gtgacgtggt acaaggatgg
     4321 gaagaagctg agctccagtt cgaaagtgcg catagaggct gcgggctgca tgcggcagct
     4381 ggtggtgcag caggcaggcc aggcagatgc tggggagtac acctgtgagg ctgggggcca
     4441 gcggctctcc ttccacctgg atgtttcaga gcccaaggcg gtgtttgcaa aggagcagct
     4501 ggcacacagg aaggtgcagg ccgaggcggg ggccattgcc acgctgagct gcgaggtggc
     4561 ccaggcccag acagaggtga cgtggtacaa ggacgggaag aagctgagct ccagctcgaa
     4621 agttcgaatg gaggctgtgg gctgcacacg gaggctggtg gtgcagcagg catgccaggc
     4681 ggacaccggg gagtatagct gcgaggccgg gggccagcgg ctctccttca gcctggacgt
     4741 ggcagagccc aaggtggtgt ttgccaagga gcagccagtg cacagggagg tgcaggccca
     4801 ggcgggggcc agcaccacac tcagctgcga ggtggctcag gcccagacgg aggtgatgtg
     4861 gtacaaggac gggaagaagc tgagcttcag ctcgaaagtg cgcatggagg ctgtgggctg
     4921 cacacggagg ctggtggtgc agcaggcggg ccaggcggtc gccggggagt acagctgcga
     4981 ggcggggagc cagcggctct ccttccacct gcacgtggca gagcccaagg cggtgtttgc
     5041 taaggagcag ccagcacaca gggaggtgca ggctgaagca ggggctagcg ccacactgag
     5101 ctgtgaggtg gcccaggccc agacagaggt gacttggtac aaggacggga agaagctgag
     5161 ctccagcttg aaagtgcatg tggaggctgc aggctgtaca cggaggctgg tggtgcagca
     5221 ggcaggccag gcagacaccg gagagtatag ctgtgaggct gggggccagc agctctcctt
     5281 ccgcctgcaa gtggcagagc ccaaggcggt gtttgccaag gagcagccag cgagcaggga
     5341 ggtgcaggct gaggcgggga ccagtgccac gctgagctgc gaggtggccc aggcccagac
     5401 agaggtgacg tggtacaagg acgggaagaa actgagctcc agctcgaaag tgcgaatgga
     5461 ggccgtgggc tgcacacgga ggctggtggt gcaggaggca ggccaggcgg acgccgggga
     5521 gtacagctgc aaggccgggg atcagcggct gtccttccac ctgcacgtgg cagagcccaa
     5581 ggtggtgttt gccaaggagc agccagcaca cagggaggtg caggctgagg cgggggccag
     5641 tgccacgctg agctgcgagg tggcccaggc ccagacagag gtgacgtggt acaaggatgg
     5701 gaagaagctg agttccagct cgaaagtgcg cgtggaggcc gtgggctgca cacggaggct
     5761 ggtggtgcag caggcgggcc aggcagaggc cggggagtac agctgcgagg cagggggtca
     5821 gcagctctcc ttccgcctgc aggtggcaga gcccaaggcg gtgtttgcca aggagcaggt
     5881 ggtgtttgcc aaggatcagc cggtgcacag ggaggtgcag gctgaggcag ggaccagcac
     5941 catgctgagc tgcgaggtgg cccaagccca gacggaggtt atgtggtaca aggacgggaa
     6001 gaagctgagc tccagctcga aaatgcgtgt ggaggccgtg ggctgcacac ggaggctggt
     6061 ggtgcaggag gcaggccagg cggacgccgg ggagtacagc tgcgaggctg ggggccagcg
     6121 gctctccttc catctgcatg tggctgagcc caaggtggtg tttgccaagg agcagccggc
     6181 atgcagggag gtgcaggcgg aggcgggggc cagtgccacg ctgagctgtg aggtggccca
     6241 gggccagatg gaggtgacat ggtacaagga cgggaagaag ctgagctcca gctcaaaagt
     6301 gcacatggag gccagcggct acacacggag gctggtagtg cagcaggcgg gccaggcgga
     6361 tgctggggag tacagctgtg aggcgggggg ccaacggctg tccttccgcc tgcacgtggc
     6421 agagctggag ccccaaattt cagagagacc ctgccgcagg gagcctctgg tggtcaagga
     6481 gcatgaagac atcatcctga ccgccacact ggccacaccc tctgcggcca cggtgacctg
     6541 gctcaaggat ggtgtggaga ttcgccgcag caagcggcat gagacagcca gccaggggga
     6601 cacccacacc ctgaccgtgc atggcgccca ggttctggac agcgccatct acagctgccg
     6661 tgtgggcgca gaggggcagg acttcccagt gcaggtggaa gaggtggccg ccaagttctg
     6721 ccggctgctg gagcctgtgt gcggcgagct gggtggcacg gtgacactgg cctgcgagct
     6781 aagcccagcg tgtgcagagg tggtgtggcg ctgcggcaac acgcagcttc gggtgggcaa
     6841 gcgcttccag atggtggccg aggggcccgt gcgctcactc actgtgttgg ggctgcgcgc
     6901 agaggacgca ggggagtacg tgtgtgagag ccgtgatgac cacaccagtg cgcagctcac
     6961 cgtcagtgtg ccccgagtgg tgaagtttat gtctgggctg agcaccgtgg tcgcagagga
     7021 gggcggcgag gccaccttcc agtgcgtggt gtcccccagt gatgtggcag tcgtgtggtt
     7081 ccgggacggt gccctgcttc agcccagcga gaagtttgcc atatcacaga gtggcgccag
     7141 ccacagcctg accatctcag acctggtgct ggaggacgcg ggccagatca ccgtggaggc
     7201 tgagggcgcc tcatcctctg ctgccctgag ggtccgagag gcgcctgtgc tgttcaaaaa
     7261 gaagctggag ccgcagacgg tggaggagcg gagctcggtg accctggagg tggagctgac
     7321 gcggccgtgg ccggagctga ggtggacacg gaacgcgacg gccctggcgc cgggaaagaa
     7381 cgtggagatc cacgccgagg gcgcccgcca ccgcctggtt ctgcacaacg taggttttgc
     7441 cgaccgtggc ttctttggct gcgagacgcc ggatgacaag acacaggcca aactcaccgt
     7501 ggagatgcgc caggtacggc tcgtacgggg cctgcaggca gtggaggcac gggagcaggg
     7561 cacggctacc atggaggtgc agctgtcgca tgcggacgtg gatggcagct ggactcgtga
     7621 cggtctgcgg ttccagcagg ggcccacgtg ccacctggct gtgcggggcc ccatgcacac
     7681 cctcacactc tcggggctgc ggccagagga tagtggcctt atggtcttca aggccgaagg
     7741 agtgcacacg tcggcgcggc tcgtggtcac cgagcttccc gtgagcttca gccgcccgct
     7801 gcaggacgtg gtgaccactg agaaggagaa ggttaccctg gagtgcgagc tgtcgcgtcc
     7861 taatgtggat gtgcgctggc tgaaggacgg tgtggagctg cgggcaggca agacgatggc
     7921 catcgcagcc cagggcgcct gcaggagcct caccatttac cggtgcgagt tcgcggatca
     7981 gggagtgtat gtgtgtgatg cccatgatgc ccagagctct gcctccgtga aggtacaagg
     8041 ccgcaacatc cagatcgtga ggcccctgga ggatgtggaa gtgatggaga aggacggtgc
     8101 caccttctcc tgtgaggtct cccacgacga agtgcctggc cagtggttct gggagggcag
     8161 taaactgcgg cccactgaca acgtgcgcat ccgccaggaa ggaaggacat acactctcat
     8221 ctaccggaga gtcctggcgg aagatgcagg agagatccaa tttgtagccg aaaatgcaga
     8281 atcgcgagcc cagctccgag tgaaggagct gccagtgacc ctcgtgcgcc cgctgcggga
     8341 caagattgcc atggagaagc accgcggtgt gctggagtgt caggtgtccc gggccagcgc
     8401 ccaggtgcgg tggttcaagg gcagtcagga gctgcagccc gggcccaagt acgagctggt
     8461 cagtgatggc ctctaccgca agctgatcat cagtgatgtc cacgcagagg acgaggacac
     8521 ctacacctgt gacgccggtg atgtcaagac cagtgcacag ttcttcgtgg aagagcaatc
     8581 catcaccatt gtgcggggtc tgcaggacgt gacagtgatg gagcccgctc ctgcctggtt
     8641 tgagtgtgag acctccatcc cctcagtgcg gccacctaag tggctcctgg ggaagacggt
     8701 gttgcaggct ggggggaacg tgggcctgga gcaggagggc acggtgcacc ggctgatgct
     8761 gcggcggacc tgctccacca tgaccgggcc cgtgcacttc accgttggca agtcgcgctc
     8821 ctctgcccgc ctggtggtct cagacatccc cgtagtcctc acacggccgt tggagcccaa
     8881 gacagggcgt gagctgcagt cagtggtcct gtcctgcgac ttccggccag cccccaaggc
     8941 tgtgcagtgg tacaaggatg acacgcccct gtctccctct gagaagttta agatgagcct
     9001 ggagggtcag atggctgagc tgcgcatcct ccggctcatg cctgctgatg ctggtgtcta
     9061 ccggtgccag gcgggcagtg cccacagcag cactgaggtc actgtggaag cgcgggaggt
     9121 gacagtgaca gggccgctac aggatgcaga ggccacggag gagggctggg ccagcttctc
     9181 ctgtgagctg tcccacgagg atgaggaggt cgagtggtcg ctcaacggga tgcccctgta
     9241 caacgacagc ttccatgaga tctcacacaa gggccggcgc cacacgctgg tactgaagag
     9301 catccagcgg gctgatgcgg gcatagtacg cgcctcctcc ctgaaggtgt cgacctctgc
     9361 ccgcctggag gtccgagtga agccggtggt gttcctgaag gcgctggatg acctgtccgc
     9421 agaggagcgc ggcaccctgg ccctgcagtg tgaagtctct gaccccgagg cccatgtggt
     9481 gtggcgcaaa gatggcgtgc agctgggccc cagtgacaag tatgacttcc tgcacacggc
     9541 gggcacgcgg gggctcgtgg tgcatgacgt gagccctgaa gacgccggcc tgtacacctg
     9601 ccacgtgggc tccgaggaga cccgggcccg ggtccgcgtg cacgatctgc acgtgggcat
     9661 caccaagagg ctgaagacaa tggaggtgct ggaaggggaa agctgcagct ttgagtgcgt
     9721 cctgtcccac gagagtgcca gcgacccggc catgtggaca gtcggtggga agacagtggg
     9781 cagctccagc cgcttccagg ccacacgtca gggccgaaaa tacatcctgg tggtccggga
     9841 ggctgcacca agtgatgccg gggaggtggt cttctctgtg cggggcctca cctccaaggc
     9901 ctcactcatt gtcagagaga ggccggccgc catcatcaag cccctggaag accagtgggt
     9961 ggcgccaggg gaggacgtgg agctgcgctg tgagctgtca cgggcgggaa cgcccgtgca
    10021 ctggctgaag gacaggaagg ccatccgcaa gagccagaag tatgatgtgg tctgcgaggg
    10081 cacgatggcc atgctggtca tccgcggggc ctcgctcaag gacgcgggcg agtacacgtg
    10141 tgaggtggag gcttccaaga gcacagccag cctccatgtg gaagaaaaag caaactgctt
    10201 cacagaggag ctgaccaatc tgcaggtgga ggagaaaggc acagctgtgt tcacgtgcaa
    10261 gacggagcac cccgcggcca cagtgacctg gcgcaagggc ctcttggagc tacgggcctc
    10321 agggaagcac cagcccagcc aggagggcct gaccctgcgg ctcaccatca gtgccctgga
    10381 gaaggcagac agcgacacct atacctgcga cattggccag gcccagtccc gggcccagct
    10441 cctagtgcaa ggccggagag tgcacatcat cgaggacctg gaggatgtgg atgtgcagga
    10501 gggctcctcg gccaccttcc gttgccggat ctccccggcc aactacgagc ctgtgcactg
    10561 gttcctggac aagacacccc tgcatgccaa cgagctcaat gagatcgatg cccagcccgg
    10621 gggctaccac gtgctgaccc tgcggcagct ggcgctcaag gactcgggca ccatctactt
    10681 tgaggcgggt gaccagcggg cctcggccgc cctgcgggtc actgagaagc caagcgtctt
    10741 ctcccgggag ctcacagatg ccaccatcac agagggtgag gacttgaccc tggtgtgcga
    10801 gaccagcacc tgcgacattc ctgtgtgctg gaccaaggat gggaagaccc tgcgggggtc
    10861 tgcccggtgc cagctgagcc atgagggcca ccgggcccag ctgctcatca ctggggccac
    10921 cctgcaggac agtggacgct acaagtgtga ggctgggggc gcctgcagca gctccattgt
    10981 cagggtgcat gcgcggccag tgcggttcca ggaggccctg aaggacctgg aggtgctgga
    11041 gggtggtgct gccacactgc gctgtgtgct gtcatctgtg gctgcgcccg tgaagtggtg
    11101 ctatggaaac aacgtcctga ggccaggtga caaatacagc ctacgccagg agggtgccat
    11161 gctggagctg gtggtccgga acctccggcc gcaggacagc gggcggtact catgctcctt
    11221 cggggaccag actacttctg ccaccctcac agtgactgcc ctgcctgccc agttcatcgg
    11281 gaaactgaga aacaaggagg ccacagaagg ggccacggcc acgctgcggt gtgagctgag
    11341 caaggcagcc cctgtggagt ggagaaaggg gtccgagacc ctcagagatg gggacagata
    11401 ctgtctgagg caggacgggg ccatgtgtga gctgcagatc cgtggcctgg ccatggtgga
    11461 tgccgcggag tactcgtgtg tgtgtggaga ggagaggacc tcagcctcac tcaccatcag
    11521 gcccatgcct gcccacttca taggaagact gagacaccaa gagagcatag aaggggccac
    11581 agccacgctg cggtgtgagc tgagcaaggc ggcccccgtg gagtggagga aggggcgtga
    11641 gagcctcaga gatggggaca gacatagcct gaggcaggac ggggctgtgt gcgagctgca
    11701 gatctgtggc ctggctgtgg cagatgctgg ggagtactcc tgtgtgtgtg gggaggagag
    11761 gacctctgcc actctcaccg tgaaggccct gccagccaag ttcacagagg gtctgaggaa
    11821 tgaagaggcc gtggaagggg ccacagccat gttgtggtgt gaactgagca aggtggcccc
    11881 tgtggagtgg aggaaggggc ccgagaacct cagagatggg gacagataca tcctgaggca
    11941 ggaggggacc aggtgtgagc tgcagatctg tggcctggcc atggcggacg ccggggagta
    12001 cttgtgtgtg tgcgggcagg agaggacctc agccacgctc accatcaggg ctctgcctgc
    12061 caggttcata gaagatgtga aaaaccagga ggccagagaa ggggccacag ctgtgctgca
    12121 gtgtgagctg aacagtgcag cccctgtgga gtggagaaag gggtctgaga cccttagaga
    12181 tggggacaga tacagcctga ggcaggacgg gactaaatgt gagctgcaga ttcgtggcct
    12241 ggccatggca gacactgggg agtactcgtg cgtgtgcggg caggagagga cctcggctat
    12301 gctcaccgtc agggctctac ccatcaagtt cacagagggt ctgaggaacg aagaggccac
    12361 agaaggggca acagccgtgc tgcggtgtga gctgagcaag atggcccccg tggagtggtg
    12421 gaaggggcat gagaccctca gagatggaga cagacacagc ctgaggcagg acggggccag
    12481 gtgtgagctg cagatccgcg gcctcgtggc agaggacgct ggggagtacc tgtgcatgtg
    12541 cgggaaggag aggacctcag ccatgctcac cgtcagggcc atgccttcca agttcataga
    12601 gggtctgagg aatgaagagg ccacagaagg ggacacggcc acgctgtggt gtgagctgag
    12661 caaggcggca ccggtggagt ggaggaaggg gcatgagacc ctcagagatg gggacagaca
    12721 cagcctgagg caggacgggt ccaggtgtga gctgcagatc cgtggcctgg ctgtggtgga
    12781 tgccggggag tactcgtgtg tgtgcgggca ggagaggacc tcagccacac tcactgtcag
    12841 ggccctgcct gccagattca tagaagatgt gaaaaaccag gaggccagag aaggggccac
    12901 ggccgtgctg caatgtgagc tgagcaaggc ggcccccgtg gagtggagga aggggtctga
    12961 gaccctcaga ggtggggaca gatacagcct gaggcaggat gggaccagat gtgagctgca
    13021 gattcatggc ctgtctgtgg cagacactgg ggagtactcg tgtgtgtgcg ggcaggagag
    13081 gacctcggcc acactcaccg tcagggccct gcctgcacga ttcactcaag atctgaagac
    13141 caaggaggcc tcagaagggg ccacagctac actgcagtgt gagctgagca aggtggcccc
    13201 tgtggaatgg aagaagggtc ctgagaccct cagagatggg ggcagataca gcctgaagca
    13261 ggatgggacg aggtgtgagc tgcagatcca tgacctgtct gtggcggatg ctggggaata
    13321 ctcatgcatg tgtggacaag agaggacctc ggccacgctc actgtcaggg ccctgcctgc
    13381 caggttcaca gagggtctga ggaatgaaga ggccatggaa ggggccacag ccacactgca
    13441 atgtgagctg agcaaggcag cccctgtgga gtggaggaaa ggccttgagg ctctcagaga
    13501 tggggacaaa tacagcctga gacaagacgg ggctgtgtgt gagctgcaga ttcatggcct
    13561 ggctatggca gataacgggg tgtactcatg tgtgtgtggg caggagagga cctcagctac
    13621 actcactgtc agggccctgc ctgccagatt catagaggat atgagaaacc agaaggccac
    13681 agaaggggct acagtcacat tgcaatgtaa gctgagaaag gcggcccccg tggagtggag
    13741 aaaggggccc aacaccctca aagatgggga caggtacagc ctgaagcagg atgggaccag
    13801 ttgtgagctg cagattcgtg gcctggtcat agcagatgct ggagaatact cgtgcatatg
    13861 tgagcaggag aggacctcgg ccacgctcac tgtcagggcc ctgccggcca gattcataga
    13921 agatgtgaga aatcacgagg ccacagaagg ggccacagct gtgctgcagt gtgagctgag
    13981 caaggcggcc cccgtggagt ggcggaaggg gtctgagacc ctcagagatg gggacagata
    14041 tagcctgagg caggacggga cgaggtgtga gctgcagatt cgtggcctgg ctgtggagga
    14101 cactggagag tatttgtgtg tgtgcgggca ggagagaacc tcagctacac tcactgtcag
    14161 ggccctgcca gccagattca tagacaacat gacaaaccag gaggccagag aaggggccac
    14221 ggccacactg cactgtgaac tgagcaaggt ggcccctgtg gagtggagga agggacctga
    14281 aaccctccga gatggggaca gacacagcct gaggcaggat gggaccaggt gtgagctgca
    14341 gattcgtggc ctgtctgtgg cagatgccgg ggagtactcg tgcgtgtgtg ggcaggagag
    14401 gacctcagcc acactcacga tcagggccct gcccgccaag ttcacaaagg gtctgaggaa
    14461 tgaagaggcc acagaagggg ccacggctat gttgcagtgt gagctgagca aggtggcccc
    14521 tgttgagtgg aggaagggac ctgaaaccct cagagatggg gacagataca acctgaggca
    14581 ggatgggacc agatgtgagc tgcagattca tggcctgtcc gtggcagaca ctggggagta
    14641 ctcatgtgta tgtggtcagg agaagacgtc ggccactctc actgtcaagg ccccacagcc
    14701 agtgttccgg gagccgctgc agagtctgca ggcggaggag ggctccacgg ccaccctgca
    14761 gtgtgagctg tctgagccca ctgctacagt ggtctggagc aagggtggcc tgcagctgca
    14821 ggccaatggg cgccgggagc cacggcttca gggctgcacc gcggagctgg tgttacagga
    14881 cctacaacgt gaagacactg gcgaatacac ttgcacctgt ggctcccagg ccaccagtgc
    14941 caccctcact gtcacagctg cgcctgtgcg gttcctccga gagctgcagc accaggaggt
    15001 ggatgaggga ggcaccgcac acttatgctg cgagctgagc cgggcgggtg cgagcgtgga
    15061 gtggcgcaag ggctccctac agctcttccc ttgtgccaag taccagatgg tgcaggatgg
    15121 tgcagctgca gagctgctgg tacgcggagt ggagcaggag gatgcgggtg actacacgtg
    15181 tgacacgggc cacacgcaga gcatggccag cctctctgtc cgtgtcccca ggcccaagtt
    15241 caagacccgg cttcagagtc tggagcagga gacaggtgac atagcccggc tgtgctgtca
    15301 gctgagtgat gcagagtcgg gggccgtggt gcaatggctc aaggagggcg tggagctgca
    15361 tgcgggcccc aagtacgaga tgcggagcca gggggccacg cgggagctgc tgatccacca
    15421 actggaggcc aaggacacgg gcgagtatgc ctgtgtgaca ggcggccaga aaaccgctgc
    15481 ctccctcagg gtcacagagc ctgaggtgac cattgtacgg gggctggttg atgcggaggt
    15541 gacggccgat gaggatgttg agttcagctg tgaggtgtcc agggctggag ccacaggcgt
    15601 gcagtggtgc ctacagggcc tgccactgca aagcaatgag gtgacagagg tggctgtgcg
    15661 ggatggccgc atccacaccc tgcggctgaa gggcgtgacg cccgaggacg ctggcactgt
    15721 ctccttccat ttgggaaacc atgcttcctc tgcccagctc accgtcagag ctcctgaggt
    15781 gaccatcctg gagcccctgc aggacgtgca gctcagtgag ggccaggatg ccagcttcca
    15841 gtgccggcta tccagagctt caggccagga ggcccgctgg gctttaggag gggtgcccct
    15901 gcaggccaac gagatgaatg acatcactgt ggagcagggc acactccacc tgctcaccct
    15961 gcacaaggtg acccttgagg atgctggaac tgtcagtttc cacgtgggca cgtgtagctc
    16021 tgaggcccag ctgaaagtca cagccaagaa cacggtggtg cgggggctgg agaatgtgga
    16081 ggcgctggag ggcggcgagg cgctgttcga gtgccagctg tcccagcccg aggtggccgc
    16141 ccacacctgg ctgctggacg acgaacccgt gcacacctcg gagaacgccg aggtggtctt
    16201 cttcgagaac ggcctgcgcc acctgctgct gctcaaaaac ttgcggccac aagacagctg
    16261 ccgggtgacc ttcctggctg gggatatggt gacgtccgca ttcctcacgg tccgaggctg
    16321 gcgcctggag atcctggagc ctctgaaaaa cgcggcggtc cgggccggcg cacaggcatg
    16381 cttcacctgc acgctcagcg aggcggtgcc cgtgggagag gcgtcctggt acatcaatgg
    16441 cgcggcagtg cagccggatg acagcgactg gactgtcacc gccgacggca gtcaccacgc
    16501 cctactgctg cgcagcgccc agccccacca cgccggggag gtcaccttcg cttgccgcga
    16561 cgccgtggcc tctgcgcggc tcaccgtgct gggcctccct gatcccccag aggatgctga
    16621 ggtggtggct cgcagcagcc acactgtgac actgtcttgg gcagctccca tgagtgatgg
    16681 aggcggtggt ctctgtggct accgcgtgga ggtgaaggag ggggccacag gccagtggcg
    16741 gctgtgccac gagctggtgc ctggacccga gtgtgtggtg gatggcctgg cccccgggga
    16801 gacctaccgc ttccgtgtgg cagctgtggg ccctgtgggt gctggggaac cggttcacct
    16861 gccccagaca gtgcggcttg cagagccacc gaagcctgtg cctccccagc cctcagcccc
    16921 tgagagccgg caggtggcag ctggtgaaga tgtctctctg gagcttgagg tggtggctga
    16981 ggctggtgag gtcatctggc acaagggaat ggagcgcatc cagcccggtg ggcggttcga
    17041 ggtggtctcc cagggtcggc aacagatgct ggtgatcaag ggcttcacgg cagaagacca
    17101 gggcgagtac cactgtggcc tggctcaggg ctccatctgc cctgcggctg ccaccttcca
    17161 ggtggcactg agcccagcct ctgtggatga ggcccctcag cccagcttgc cccccgaggc
    17221 agcccaggag ggtgacctgc acctactgtg ggaggccctg gctcggaaac gtcgcatgag
    17281 ccgtgagccc acgctggact ccattagcga gctgccagag gaggacggcc gctcgcagcg
    17341 cctgccacag gaggcagagg aggtggcacc tgatctctct gaaggctact ccacggccga
    17401 tgagctggcc cgcactggag atgctgacct ctcacacacc agctctgatg atgagtcccg
    17461 ggcaggcacc ccttccctgg tcacctacct caagaaggct gggaggccag gcacctcacc
    17521 actggccagc aaggttgggg ccccagcagc cccctctgtg aagccacagc agcagcagga
    17581 gccactggct gctgtgcgcc caccactggg agacctgagc accaaagacc tgggtgatcc
    17641 ctcaatggac aaggcagctg tgaagatcca ggctgccttt aagggctaca aggtccggaa
    17701 ggagatgaag cagcaggaag ggcccatgtt ctcccacaca tttggggaca ccgaggcaca
    17761 ggtgggggat gccctgcggc tggagtgtgt cgtggccagc aaggcagatg tgcgagcccg
    17821 ctggctgaag gatggtgtgg agctgaccga tgggcggcac catcacatcg accagcttgg
    17881 ggatggcacc tgctctctgc tgatcactgg cctggaccgt gctgatgctg gctgctacac
    17941 ctgtcaggtg agcaacaagt ttggccaggt gacccacagt gcctgtgtgg tggtcagtgg
    18001 gtcagagagt gaagccgaga gctcctctgg gggtgagctg gacgatgcct tccgccgggc
    18061 tgcccgtcgg ctgcaccggc tcttccgcac caaaagtccg gctgaagttt cagatgagga
    18121 gctcttcctg agtgcagacg agggccctgc agagccagag gagcccgcgg actggcagac
    18181 ataccgcgaa gatgagcatt tcatctgcat ccgttttgag gcgctcactg aggcccgcca
    18241 ggcggtaact cgcttccagg agatgtttgc cacactgggc attggggtgg agatcaagct
    18301 ggtggaacag gggcctcgga gggtagagat gtgcatcagc aaagagactc ctgcccctgt
    18361 ggtgcctcca gagccattgc ccagcctact gacttctgac gctgccccag tgttcctgac
    18421 tgagttgcag aaccaagaag tgcaggatgg gtatcctgtg agctttgact gcgtggtgac
    18481 aggtcagccc atgcccagtg tgcgctggtt caaggatggg aagttgttgg aggaggatga
    18541 tcactacatg attaatgaag accaacaggg tggccatcag ctcatcatca cagccgtggt
    18601 gccagcagac atgggcgtct accgctgcct ggccgagaac agcatgggtg tctcctccac
    18661 caaggctgag ctccgtgtgg acttgacaag cacagactat gacactgcag cagatgccac
    18721 ggagtcctca tcctacttca gtgcccaagg ctacctgtcc agccgggagc aggagggaac
    18781 agagtccacc actgatgagg gccagctgcc ccaggtggtg gaggagctga gagacctcca
    18841 ggtggcccct ggcacacgcc tggccaagtt ccagctcaag gtgaaaggct accctgctcc
    18901 cagattatac tggttcaaag atggccagcc cctgaccgca tctgcccaca tccgcatgac
    18961 tgacaagaag atcctgcaca ccctggagat catctccgtc acccgggagg actctggcca
    19021 gtatgcagcc tatatcagca atgccatggg tgctgcctac tcgtctgccc ggctgctggt
    19081 tcgaggccct gatgagccag aagagaagcc tgcatcagat gtgcatgagc agctggtgcc
    19141 gccccgaatg ctggagaggt tcacccccaa gaaagtgaag aaaggctcca gcatcacctt
    19201 ctctgtgaag gtagaaggac gcccggtgcc caccgtgcac tggctcaggg aggaggctga
    19261 gagaggcgtg ctgtggattg gccctgacac accgggctac accgtggcca gctctgcgca
    19321 gcagcacagc ctggtcctgc tggacgtggg ccggcagcac cagggcacct acacatgcat
    19381 tgccagcaac gctgccggcc aggccctctg ctccgccagc ctgcacgtct cgggcctgcc
    19441 taaggtggag gagcaggaga aagtgaagga agcgctgatt tccactttcc tgcaggggac
    19501 cacacaagcc atctcagcac aggggttgga aactgcgagt tttgctgacc ttggtgggca
    19561 gaggaaagaa gagcctctgg ctgccaagga ggccctcggc cacctgtccc tcgctgaggt
    19621 gggcacagag gagttcctgc agaaactgac ctcccagatc actgagatgg tatcggccaa
    19681 gatcacgcag gccaagctgc aggtgcccgg aggtgacagt gatgaggact ccaagacacc
    19741 atctgcatcc ccccgccatg gccgatcacg gccatcctcc agcatccagg agtcttcctc
    19801 agagtcagag gacggcgatg cccgaggcga gatctttgac atctacgtgg tcaccgctga
    19861 ctacctgccc ctaggggctg agcaggatgc catcacgctg cgggaaggcc agtatgtgga
    19921 ggtcctggat gcagcccacc cactgcgctg gcttgtccgc accaagccca ccaagtccag
    19981 cccctcacgg cagggctggg tgtcaccagc ctacctggac aggaggctca agctgtcacc
    20041 tgagtggggg gccgctgagg cccctgagtt ccctggggag gctgtgtctg aagacgaata
    20101 caaggcaagg ctgagctctg tgatccagga gctgctgagt tctgagcagg ccttcgtgga
    20161 ggagctgcag ttcctgcaga gccaccacct gcagcacctg gagcgctgcc cccacgtgcc
    20221 catagctgtg gccggccaga aggcagtcat cttccgcaat gtgcgggaca tcggccgctt
    20281 ccacagcagc ttcctgcagg agttgcagca gtgcgacacg gacgacgacg tggccatgtg
    20341 cttcatcaag aaccaggcgg cctttgagca gtacctggag ttcctggtgg ggcgtgtgca
    20401 ggctgagtcg gtggtcgtca gcacggccat ccaggagttc tacaagaaat acgcggagga
    20461 ggccctgttg gcaggggacc cctctcagcc cccgccacca cctctgcagc actacctgga
    20521 gcagccagtg gagcgggtgc agcgctacca ggccttgctg aaggagctga tccgcaacaa
    20581 ggcgcggaac agacagaact gcgcgctgct ggagcaggcc tatgccgtgg tgtctgccct
    20641 gccacagcgc gctgagaaca agctgcacgt gtccctcatg gagaactacc caggcaccct
    20701 gcaggccctg ggcgagccca tccgccaggg ccacttcatc gtgtgggagg gtgcaccggg
    20761 ggcccgcatg ccctggaagg gccacaaccg tcacgtgttc ctcttccgca accacctggt
    20821 aatctgcaag ccccggcgag actcccgcac cgataccgtc agctacgtgt tccggaacat
    20881 gatgaagctg agcagcatcg acctgaacga ccaggtggag ggggatgacc gcgccttcga
    20941 ggtgtggcag gagcgggagg actcggtgcg caagtacctg ctgcaggcac ggacagccat
    21001 tatcaagagc tcgtgggtga aggagatctg tggcatccag cagcgtctgg ccctgcctgt
    21061 gtggcggccc ccggactttg aagaggagct ggccgactgc acagccgagc tgggtgagac
    21121 agtcaagctg gcctgccgcg tgacgggcac acccaagcct gtcatcagct ggtacaaaga
    21181 tgggaaagca gtgcaggtgg acccccacca catcctcatt gaagaccctg atggctcgtg
    21241 tgcactcatc ctggacagcc tgaccggtgt ggactctggc cagtacatgt gcttcgcggc
    21301 cagcgccgct ggcaactgca gtaccctggg caagatcctg gtgcaagtcc caccacggtt
    21361 cgtgaacaag gtccgggcct caccctttgt ggagggagag gacgcccagt tcacctgcac
    21421 catcgaaggc gccccgtacc cgcagatcag gtggtacaag gacggggccc tgctgaccac
    21481 tggcaacaag ttccagacac tgagtgagcc tcgcagcggc ctgctagtgc tggtgatccg
    21541 ggcggccagc aaggaggacc tggggctcta cgagtgtgag ctggtgaacc ggctgggctc
    21601 cgcgcgggct agtgcggagc tgcgcattca gagccccatg ctgcaggccc aggagcagtg
    21661 tcacagggag cagctcgtgg ctgcagtgga agacaccacc ctggagcgag cggaccagga
    21721 ggtcacatct gtcctgaaga gactgctggg ccccaaggcg ccaggcccct ccacagggga
    21781 cctcactggc cctggcccct gccccagggg ggcacccgca ctccaggaaa ccggctccca
    21841 gcccccagtc accggaactt cggaggcacc tgccgtgccc ccgagggtgc cacagcccct
    21901 cctccacgaa ggcccagagc aggagccgga ggccattgcc agagcccagg aatggactgt
    21961 gcccattcgg atggagggtg cagcctggcc cggggcaggc acaggggagc tgctctggga
    22021 cgtccacagc cacgtggtca gagagaccac acagaggacc tacacatacc aggccatcga
    22081 cacgcacacc gcacggcccc catccatgca ggtaaccatc gaggatgtgc aggcacagac
    22141 aggcggaacg gcccaattcg aggctatcat tgagggcgac ccacagccct cggtgacctg
    22201 gtacaaggac agcgtccagc tggtggacag cacccggctt agccagcagc aagaaggcac
    22261 cacatactcc ctggtgctga ggcatgtggc ctcgaaggat gccggcgttt acacctgcct
    22321 ggcccaaaac actggtggcc aggtgctctg caaggcagag ctgctggtgc ttggggggga
    22381 caatgagccg gactcagaga agcaaagcca ccggaggaag ctgcactcct tctatgaggt
    22441 caaggaggag attggaaggg gcgtgtttgg cttcgtaaaa agagtgcagc acaaaggaaa
    22501 caagatcttg tgcgctgcca agttcatccc cctacggagc agaactcggg cccaggcata
    22561 cagggagcga gacatcctgg ccgcgctgag ccacccgctg gtcacggggc tgctggacca
    22621 gtttgagacc cgcaagaccc tcatcctcat cctggagctg tgctcatccg aggagctgct
    22681 ggaccgcctg tacaggaagg gcgtggtgac ggaggccgag gtcaaggtct acatccagca
    22741 gctggtggag gggctgcact acctgcacag ccatggcgtt ctccacctgg acataaagcc
    22801 ctctaacatc ctgatggtgc atcctgcccg ggaagacatt aaaatctgcg actttggctt
    22861 tgcccagaac atcaccccag cagagctgca gttcagccag tacggctccc ctgagttcgt
    22921 ctcccccgag atcatccagc agaaccctgt gagcgaagcc tccgacattt gggccatggg
    22981 tgtcatctcc tacctcagcc tgacctgctc atccccattt gccggcgaga gtgaccgtgc
    23041 caccctcctg aacgtcctgg aggggcgcgt gtcatggagc agccccatgg ctgcccacct
    23101 cagcgaagac gccaaagact tcatcaaggc tacgctgcag agagcccctc aggcccggcc
    23161 tagtgcggcc cagtgcctct cccacccctg gttcctgaaa tccatgcctg cggaggaggc
    23221 ccacttcatc aacaccaagc agctcaagtt cctcctggcc cgaagtcgct ggcagcgttc
    23281 cctgatgagc tacaagtcca tcctggtgat gcgctccatc cctgagctgc tgcggggccc
    23341 acccgacagc ccctccctcg gcgtagcccg gcacctctgc agggacactg gtggctcctc
    23401 cagttcctcc tcctcctctg acaacgagct cgccccattt gcccgggcta agtcactgcc
    23461 accctccccg gtgacacact caccactgct gcacccccgg ggcttcctgc ggccctcggc
    23521 cagcctgcct gaggaagccg aggccagtga gcgctccacc gaggccccag ctccgcctgc
    23581 atctcccgag ggtgccgggc caccggccgc ccagggctgc gtgccccggc acagcgtcat
    23641 ccgcagcctg ttctaccacc aggcgggtga gagccctgag cacggggccc tggccccggg
    23701 gagcaggcgg cacccggccc ggcggcggca cctgctgaag ggcgggtaca ttgcgggggc
    23761 gctgccaggc ctgcgcgagc cactgatgga gcaccgcgtg ctggaggagg aggccgccag
    23821 ggaggagcag gccaccctcc tggccaaagc cccctcattc gagactgccc tccggctgcc
    23881 tgcctctggc acccacttgg cccctggcca cagccactcc ctggaacatg actctccgag
    23941 caccccccgc ccctcctcgg aggcctgcgg tgaggcacag cgactgcctt cagccccctc
    24001 cgggggggcc cctatcaggg acatggggca ccctcagggc tccaagcagc ttccatccac
    24061 tggtggccac ccaggcactg ctcagccaga gaggccatcc ccggacagcc cttgggggca
    24121 gccagcccct ttctgccacc ccaagcaggg ttctgccccc caggagggct gcagccccca
    24181 cccagcagtt gccccatgcc ctcctggctc cttccctcca ggatcttgca aagaggcccc
    24241 cttagtaccc tcaagcccct tcttgggaca gccccaggca ccccctgccc ctgccaaagc
    24301 aagcccccca ttggactcta agatggggcc tggagacatc tctcttcctg ggaggccaaa
    24361 acccggcccc tgcagttccc cagggtcagc ctcccaggcg agctcttccc aagtgagctc
    24421 cctcagggtg ggctcctccc aggtgggcac agagcctggc ccctccctgg atgcggaggg
    24481 ctggacccag gaggctgagg atctgtccga ctccacaccc accttgcagc ggcctcagga
    24541 acaggcgacc atgcgcaagt tctccctggg tggtcgcggg ggctacgcag gcgtggctgg
    24601 ctatggcacc tttgcctttg gtggagatgc agggggcatg ctggggcagg ggcccatgtg
    24661 ggccaggata gcctgggctg tgtcccagtc agaggaggag gagcaggagg aggccagggc
    24721 tgagtcccag tcggaggagc agcaggaggc cagggctgag agcccactgc cccaggtcag
    24781 tgcaaggcct gtgcctgagg tcggcagggc tcccaccagg agctctccag agcccacccc
    24841 atgggaggac atcgggcagg tctccctggt gcagatccgg gacctgtcag gtgatgcgga
    24901 ggcggccgac acaatatccc tggacatttc cgaggtggac cccgcctacc tcaacctctc
    24961 agacctgtac gatatcaagt acctcccatt cgagtttatg atcttcagga aagtccccaa
    25021 gtccgctcag ccagagccgc cctcccccat ggctgaggag gagctggccg agttcccgga
    25081 gcccacgtgg ccctggccag gtgaactggg cccccacgca ggcctggaga tcacagagga
    25141 gtcagaggat gtggacgcgc tgctggcaga ggctgccgtg ggcaggaagc gcaagtggtc
    25201 ctcgccgtca cgcagcctct tccacttccc tgggaggcac ctgccgctgg atgagcctgc
    25261 agagctgggg ctgcgtgaga gagtgaaggc ctccgtggag cacatctccc ggatcctgaa
    25321 gggcaggccg gaaggtctgg agaaggaggg gccccccagg aagaagccag gccttgcttc
    25381 cttccggctc tcaggtctga agagctggga ccgagcgccg acattcctaa gggagctctc
    25441 agatgagact gtggtcctgg gccagtcagt gacactggcc tgccaggtgt cagcccagcc
    25501 agctgcccag gccacctgga gcaaagacgg agcccccctg gagagcagca gccgtgtcct
    25561 catctctgcc accctcaaga acttccagct tctgaccatc ctggtggtgg tggctgagga
    25621 cctgggtgtg tacacctgca gcgtgagcaa tgcgctgggg acagtgacca ccacgggcgt
    25681 cctccggaag gcagagcgcc cctcatcttc gccatgcccg gatatcgggg aggtgtacgc
    25741 ggatggggtg ctgctggtct ggaagcccgt ggaatcctac ggccctgtga cctacattgt
    25801 gcagtgcagc ctagaaggcg gcagctggac cacactggcc tccgacatct ttgactgctg
    25861 ctacctgacc agcaagctct cccggggtgg cacctacacc ttccgcacgg catgtgtcag
    25921 caaggcagga atgggtccct acagcagccc ctcggagcaa gtcctcctgg gagggcccag
    25981 ccacctggcc tctgaggagg agagccaggg gcggtcagcc caacccctgc ccagcacaaa
    26041 gaccttcgca ttccagacac agatccagag gggccgcttc agcgtggtgc ggcaatgctg
    26101 ggagaaggcc agcgggcggg cgctggccgc caagatcatc ccctaccacc ccaaggacaa
    26161 gacagcagtg ctgcgcgaat acgaggccct caagggcctg cgccacccgc acctggccca
    26221 gctgcacgca gcctacctca gcccccggca cctggtgctc atcttggagc tgtgctctgg
    26281 gcccgagctg ctcccctgcc tggccgagag ggcctcctac tcagaatccg aggtgaagga
    26341 ctacctgtgg cagatgttga gtgccaccca gtacctgcac aaccagcaca tcctgcacct
    26401 ggacctgagg tccgagaaca tgatcatcac cgaatacaac ctgctcaagg tcgtggacct
    26461 gggcaatgca cagagcctca gccaggagaa ggtgctgccc tcagacaagt tcaaggacta
    26521 cctagagacc atggctccag agctcctgga gggccagggg gctgttccac agacagacat
    26581 ctgggccatc ggtgtgacag ccttcatcat gctgagcgcc gagtacccgg tgagcagcga
    26641 gggtgcacgc gacctgcaga gaggactgcg caaggggctg gtccggctga gccgctgcta
    26701 cgcggggctg tccgggggcg ccgtggcctt cctgcgcagc actctgtgcg cccagccctg
    26761 gggccggccc tgcgcgtcca gctgcctgca gtgcccgtgg ctaacagagg agggcccggc
    26821 ctgttcgcgg cccgcgcccg tgaccttccc taccgcgcgg ctgcgcgtct tcgtgcgcaa
    26881 tcgcgagaag agacgcgcgc tgctgtacaa gaggcacaac ctggcccagg tgcgctgagg
    26941 gtcgccccgg ccacaccctt ggtctccccg ctgggggtcg ctgcagacgc gccaataaaa
    27001 acgcacagcc gggcgagaa
//
