LOCUS       XM_047438676            4110 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens NACHT and WD repeat domain containing 1
            (NWD1), transcript variant X7, mRNA.
ACCESSION   XM_047438676
VERSION     XM_047438676.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000019.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4110
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
     gene            1..4110
                     /gene="NWD1"
                     /note="NACHT and WD repeat domain containing 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 6 ESTs, 8 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     7 samples with support for all annotated introns"
                     /db_xref="GeneID:284434"
                     /db_xref="HGNC:HGNC:27619"
                     /db_xref="MIM:616250"
     CDS             775..4110
                     /gene="NWD1"
                     /codon_start=1
                     /product="NACHT domain- and WD repeat-containing protein 1
                     isoform X5"
                     /protein_id="XP_047294632.1"
                     /db_xref="GeneID:284434"
                     /db_xref="HGNC:HGNC:27619"
                     /db_xref="MIM:616250"
                     /translation="MQRGKPCRALPTLKCQTFCQRHGLMFEVVDLRWGIRNIEATDHL
                     TTELCLEEVDRCWKTSIGPAFVALIGDQYGPCLIPSRIDEKEWEVLRDHLTARPSDLE
                     LVARYFQRDENAFPPTYVLQAPGTGEACEPEEATLTSVLRSGAQEARRLGLITQEQWQ
                     HYHRSVIEWEIERSLLSSEDREQGATVFLREIQDLHKHILEDCALRMVDRLADGCLDA
                     DAQNLLSSLKSHITDMHPGVLKTHRLPWSRDLVNPKNKTHACYLKELGEQFVVRANHQ
                     VLTRLRELDTAGQELAWLYQEIRHHLWQSSEVIQTFCGRQELLARLGQQLRHDDSKQH
                     TPLVLFGPPGIGKTALMCKLAEQMPRLLGHKTVTVLRLLGTSQMSSDARGLLKSICFQ
                     VCLAYGLPLPPAQVLDAHTRVVQFFHTLLHTVSCRNFESLVLLLDAMDDLDSVRHARR
                     VPWLPLNCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLL
                     AAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTVPVPLATTAEEATHQL
                     CTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYRDWTPPSKELL
                     RFPPLLWVRLRRDLGYYLARRPVDGFTLLAIAHRQLVEVVRERYLSGSERAKRHGVLA
                     DFFSGTWSQGTKKLITLPLVGKPLNLDRKVAPQPLWFSHTVANLRKLKELPYHLLHSG
                     RLEELKQEVLGSMSWISCRGISGGIEDLLDDFDLCAPHLDSPEVGLVREALQLCRPAV
                     ELRGMERSLLYTELLARLHFFATSHPALVGQLCQQAQSWFQLCAHPVLVPLGGFLQPP
                     GGPLRATLSGCHKGITAMAWGVEEKLLVIGTQDGIMAVWDMEEQHVIHMLTGHTGEVR
                     CVKIFAKGTLANSASKDYTLHLWNLLSGQEKFTIWDGGSKNPAEPQIWNLHVDEAHKV
                     VYSASGSKINAWNLETAEPVFHILGDASDPWMCMAVLASQATLLTVSRDGVVSLWSSA
                     TGKLQGKQHMSSIKEETPTCAVSVQKQGKLVTGFSNGSISLALEDRCGYSWRTRGAFA
                     DSWPWIWNMKTWWRRLFLVLRTT"
ORIGIN      
        1 agttgctggg agaattgggc aaggagagac ccataaaata cctaagacga aagttactag
       61 gatagccagg ggcttgtctt ccgggtggcg ccgaggccag gaaactgtcc tctctaacct
      121 atttccccag aggagtctaa attggtcgtt caactaccag caaaggctaa agagaggctg
      181 gagcccccag gacagccaga acgctgacac tgcaaagggc ctctgtcctt actggggaag
      241 cccagtcctg ctcagctgtc ttcttcagca acaaacagaa gtccagaaag agaaacagtt
      301 gtggaggaag ctgttgtgat gataatttac tgagcaccta ctatgtgcca ggcacgccag
      361 ccttaccaga caagatcctt gggctcatgg aattcacttt ctcgtgggac agacaaacaa
      421 taacatgtag aaacatatca gctgttgcag gcagtaacca agggagcgtg gccaggcgct
      481 gaagtgaatt cgggtccaag gagcctgctg ggacccagga aaacgagaga aggaacagaa
      541 attgtggtgg aggcaaattc aagatcagaa gattggggag gaggtgctaa gagaggtctg
      601 gagagatgct gggacccaga actggggcct cagtgagatc agcaggctgc agctaaactg
      661 tggtatccag accatgcggc cgatgccctg ggagggagac cacttgctta agtcctccag
      721 gagggcgatg gaggagccgg cattccaacc aggctcacgg atgccaagat atggatgcag
      781 agagggaagc cctgcagagc actgcctacc ctgaagtgcc agaccttctg ccagaggcac
      841 ggcttgatgt ttgaggtcgt tgatctgagg tggggtattc ggaacattga agccactgac
      901 cacttgacca cagaactctg cttggaggag gttgaccggt gttggaaaac atccataggg
      961 ccagcttttg ttgccctcat cggtgatcag tacggcccct gtctgattcc ctcgcggatc
     1021 gatgagaagg agtgggaggt attgagggac catctgactg ccaggccaag tgacctggag
     1081 ctggtggcac gatacttcca gagggacgag aatgcgtttc ctcccaccta cgtcctgcag
     1141 gcaccaggta ctggggaggc ctgtgaacca gaggaggcca ccttaacttc tgtcctacgc
     1201 tctggagccc aggaggcccg gaggctgggg ctcatcaccc aggagcagtg gcagcactac
     1261 caccggtcag tcattgagtg ggagatagag cggagcctgc tgagctcaga ggaccgggaa
     1321 cagggagcca ccgtcttcct tagagagatc caagacctcc acaaacacat ccttgaagac
     1381 tgcgccctta ggatggtgga ccggctcgcg gatggctgcc tggacgctga tgcccagaac
     1441 cttctcagca gcctcaaaag tcacatcact gacatgcacc caggggtcct caagacccac
     1501 cgcctgccgt ggagccgcga cttggtgaac cccaagaaca agactcacgc ctgctacctg
     1561 aaggagctgg gtgagcagtt tgtggtgagg gccaatcacc aggtcctcac acgcctccgt
     1621 gagctggata cggccggaca ggagttggcg tggctctacc aagagatccg ccaccacctt
     1681 tggcagagct cggaggtcat tcagaccttc tgcggacgcc aggaactcct ggcccggctt
     1741 gggcagcagc tcaggcacga tgacagcaag cagcacaccc ccctggtact ctttgggccc
     1801 ccaggcattg gaaagacagc cctgatgtgc aagctggctg agcagatgcc aaggctgctg
     1861 gggcacaaga cagtgaccgt cctgcggctg ctggggacgt cacaaatgag ctcagatgcc
     1921 cgtggcctgc tgaagagcat ctgcttccag gtgtgcctgg cctatgggct gcccttgccc
     1981 cctgcccagg ttctggacgc ccacaccagg gtggtccagt ttttccatac cctcctccac
     2041 actgtctctt gcagaaactt cgagtctctc gtgctcctgc tggatgctat ggatgacctg
     2101 gactctgtcc gccatgctcg gagggttccc tggctgcctc tcaactgccc cccgagggtg
     2161 cacctcatcc tctcagcttg ctcgggggca ctgggggttt tggacacctt gcagcgggtg
     2221 ctcctggacc cggaggccta ctgggaggtg aagccccttt ccggaaacca aggccagcag
     2281 atgatccaac tcctgctggc agctgcaagg aggacgctga gcccggtgca cacagatttg
     2341 ctctgggcca gcctcccaga gtgtgggaac ccagggcggc tgaggctggc gtttgaggaa
     2401 gcccggaaat gggcctcttt caccgtgcct gtcccgctgg ccaccaccgc agaggaagcc
     2461 acgcaccaac tctgcacccg cctggagcag acacacgggc agctcctcgt ggcccacgtg
     2521 ctgggctaca ttgtgtcttc ccgacacggt ctctcggagg cggagctgaa ggatgttttg
     2581 tccctggacg acgaggtcct gcaggatgtg taccgagatt ggaccccgcc cagcaaggag
     2641 ctgctgcgct tcccgcccct gctgtgggtg cggcttcgtc gggatctggg atactacttg
     2701 gcccggcggc ccgtggatgg cttcaccctc ctggccattg cccacagaca gctggtcgag
     2761 gtggtccgtg agcgctacct gtcaggatcc gagagagcca agaggcatgg cgtcctggcc
     2821 gacttcttct cagggacctg gagccagggt accaagaagc tcatcactct gccacttgtg
     2881 gggaaaccac tgaacttgga ccgaaaggtg gccccgcagc ctctgtggtt ctcacatacg
     2941 gttgcaaacc tgcggaagct gaaggagttg ccctatcacc tgcttcactc gggccgcctg
     3001 gaggagctga aacaggaggt tctgggcagc atgagctgga tttcctgccg gggcatctct
     3061 gggggcattg aagacctgct ggatgacttt gacctgtgtg cccctcacct ggactcccct
     3121 gaggttggcc tggtccgtga agccctccag ctctgccgcc ctgctgtgga gctccgaggc
     3181 atggagagga gcctcctgta cacagaactg ctggccagac tccatttctt cgccacctca
     3241 catccagcac tggtgggaca gctatgccaa caggcccaga gctggttcca gttgtgcgca
     3301 caccctgtgc tggtgcccct cggaggattc ctccagcccc cgggaggacc cctccgggca
     3361 actctcagcg gctgtcacaa aggcatcacc gccatggcat ggggtgtgga ggagaagctg
     3421 ctggtgattg gcacccagga tggcatcatg gctgtgtggg acatggaaga gcagcatgtg
     3481 atccacatgc taactggaca cacaggagag gtgaggtgtg tgaaaatatt tgccaaaggg
     3541 accctcgcca actctgcttc aaaggattac acgctgcact tgtggaactt actctctggc
     3601 caggagaaat ttaccatttg ggatggaggc tcaaaaaatc ccgctgaacc tcagatctgg
     3661 aaccttcatg tggatgaggc acacaaagtt gtgtattcag catctggctc aaagatcaat
     3721 gcttggaatc tggaaactgc agagccggta ttccatatcc tgggagatgc ctctgatcct
     3781 tggatgtgca tggccgtgct ggcctcccag gccacactgc tgacagtgtc cagggatggt
     3841 gtggtcagtc tgtggagctc agctacggga aaacttcagg ggaagcaaca tatgtccagc
     3901 atcaaagaag aaacacctac ctgtgccgtc tcagtccaga agcaaggaaa gcttgttacc
     3961 gggtttagca atggctccat ctctttggct ttggaagatc ggtgcggata ttcttggcgg
     4021 actcgagggg ctttcgccga ttcatggcca tggatctgga acatgaagac atggtggaga
     4081 cggctgtttt tggtactgag aacaacctga
//
