LOCUS       NM_001382304            3214 bp    mRNA    linear   PRI 29-OCT-2022
DEFINITION  Homo sapiens NUT family member 2D (NUTM2D), transcript variant 1,
            mRNA.
ACCESSION   NM_001382304
VERSION     NM_001382304.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3214)
  AUTHORS   Deloukas P, Earthrowl ME, Grafham DV, Rubenfield M, French L,
            Steward CA, Sims SK, Jones MC, Searle S, Scott C, Howe K, Hunt SE,
            Andrews TD, Gilbert JG, Swarbreck D, Ashurst JL, Taylor A, Battles
            J, Bird CP, Ainscough R, Almeida JP, Ashwell RI, Ambrose KD,
            Babbage AK, Bagguley CL, Bailey J, Banerjee R, Bates K, Beasley H,
            Bray-Allen S, Brown AJ, Brown JY, Burford DC, Burrill W, Burton J,
            Cahill P, Camire D, Carter NP, Chapman JC, Clark SY, Clarke G, Clee
            CM, Clegg S, Corby N, Coulson A, Dhami P, Dutta I, Dunn M, Faulkner
            L, Frankish A, Frankland JA, Garner P, Garnett J, Gribble S,
            Griffiths C, Grocock R, Gustafson E, Hammond S, Harley JL, Hart E,
            Heath PD, Ho TP, Hopkins B, Horne J, Howden PJ, Huckle E, Hynds C,
            Johnson C, Johnson D, Kana A, Kay M, Kimberley AM, Kershaw JK,
            Kokkinaki M, Laird GK, Lawlor S, Lee HM, Leongamornlert DA, Laird
            G, Lloyd C, Lloyd DM, Loveland J, Lovell J, McLaren S, McLay KE,
            McMurray A, Mashreghi-Mohammadi M, Matthews L, Milne S, Nickerson
            T, Nguyen M, Overton-Larty E, Palmer SA, Pearce AV, Peck AI, Pelan
            S, Phillimore B, Porter K, Rice CM, Rogosin A, Ross MT, Sarafidou
            T, Sehra HK, Shownkeen R, Skuce CD, Smith M, Standring L, Sycamore
            N, Tester J, Thorpe A, Torcasso W, Tracey A, Tromans A, Tsolas J,
            Wall M, Walsh J, Wang H, Weinstock K, West AP, Willey DL, Whitehead
            SL, Wilming L, Wray PW, Young L, Chen Y, Lovering RC, Moschonas NK,
            Siebert R, Fechtel K, Bentley D, Durbin R, Hubbard T,
            Doucette-Stamm L, Beck S, Smith DR and Rogers J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 10
  JOURNAL   Nature 429 (6990), 375-381 (2004)
   PUBMED   15164054
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL645612.10.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9304719.495915.1,
                                           ERR3218376.251928.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000381697.7/ ENSP00000371116.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-688               AL645612.10        3909-4596
            689-1388            AL645612.10        6646-7345
            1389-1517           AL645612.10        9303-9431
            1518-1657           AL645612.10        10404-10543
            1658-2040           AL645612.10        10986-11368
            2041-2157           AL645612.10        11854-11970
            2158-3214           AL645612.10        12304-13360
FEATURES             Location/Qualifiers
     source          1..3214
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q23.2"
     gene            1..3214
                     /gene="NUTM2D"
                     /gene_synonym="FAM22D"
                     /note="NUT family member 2D"
                     /db_xref="GeneID:728130"
                     /db_xref="HGNC:HGNC:23447"
     exon            1..688
                     /gene="NUTM2D"
                     /gene_synonym="FAM22D"
                     /inference="alignment:Splign:2.1.0"
     CDS             523..2943
                     /gene="NUTM2D"
                     /gene_synonym="FAM22D"
                     /note="isoform 1 is encoded by transcript variant 1;
                     family with sequence similarity 22, member D; protein
                     FAM22D; NUT family member 2A pseudogene"
                     /codon_start=1
                     /product="NUT family member 2D isoform 1"
                     /protein_id="NP_001369233.1"
                     /db_xref="CCDS:CCDS91292.1"
                     /db_xref="GeneID:728130"
                     /db_xref="HGNC:HGNC:23447"
                     /translation="MFQEPVYFQIFLFQLDSGASGEPGHSLGLTLGFSHCGNCQTAVV
                     SAQPEGMASNGAYPALGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGG
                     PLVLSNFPSTPLVTEQDGCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQ
                     APGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLP
                     PIVSQGNAGPWPQGAHGEGSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLP
                     QSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFL
                     EFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTA
                     CLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVD
                     IMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPDPGLLSYTDKLCSQKDFVTKVE
                     AVIHPQFLEELLSPDPQMDFLALSQELEQEEGLTLAQLVEKRLLPLKEKQHARAAPSR
                     GTARLDSSSSKFAAGQGAERDVPDPQQGVGMETCPPQTTARDSQGRGRAHTGMARSKD
                     SVVLLGCQDSPGLRAARPTSPPQDHRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSE
                     EEELPSLAFLLGSQHKLLPWWLPQSPVPASGLLSPEKWGPQGTHQSPSAERRGLNLAP
                     SPANKAKKRPLFGSLSPAEKTPHPGPGLRVSGEQSLTWGLGGPSQSQKRKGDPLVSRK
                     EKKQRCSQ"
     exon            689..1388
                     /gene="NUTM2D"
                     /gene_synonym="FAM22D"
                     /inference="alignment:Splign:2.1.0"
     exon            1389..1517
                     /gene="NUTM2D"
                     /gene_synonym="FAM22D"
                     /inference="alignment:Splign:2.1.0"
     exon            1518..1657
                     /gene="NUTM2D"
                     /gene_synonym="FAM22D"
                     /inference="alignment:Splign:2.1.0"
     exon            1658..2040
                     /gene="NUTM2D"
                     /gene_synonym="FAM22D"
                     /inference="alignment:Splign:2.1.0"
     exon            2041..2157
                     /gene="NUTM2D"
                     /gene_synonym="FAM22D"
                     /inference="alignment:Splign:2.1.0"
     exon            2158..3214
                     /gene="NUTM2D"
                     /gene_synonym="FAM22D"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3191..3196
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NUTM2D"
                     /gene_synonym="FAM22D"
                     /note="hexamer: AATAAA"
     polyA_site      3214
                     /gene="NUTM2D"
                     /gene_synonym="FAM22D"
                     /note="major polyA site"
ORIGIN      
        1 cgtaaggctg gcctgctggt gtggacagag attccagcaa catgcatgac ctgggggtac
       61 aaggattgct tcctaaacaa tgataagcac acagccacct aatagtctgg atcggctgag
      121 accatcctga tttcaaacac ccagtcccct tgccttccta agaacccctg tgtttctcag
      181 actgaaaatg tgttttgaac tttgttcacg aagtgaggcc gctgttgaaa ttcgtcaaga
      241 ctgggaaaga gccaaagtgg gaaggagcat gggttgattg gcacaaaagt aggtctgctg
      301 ataaagaatg gaagtaaagg ggccatcagg tagaagcttt tgctgtgagt cagaaggaca
      361 atttaaaagt tgcctaaaga ggcacacgcc atctctgctg ctgccttcca gttggaaggg
      421 aaactcaggt tcttgcctaa tggccgaagc ccttcacaga atgtccccca cccctaacag
      481 ctgcccactg cccctccccc tctgcagaat gtctggggtc ctatgttcca ggaacctgtt
      541 tactttcaaa ttttcctgtt tcagttggac tcaggagcat ctggtgagcc aggtcactct
      601 ctgggtctta cccttggctt ttctcattgt ggaaactgcc agacagcggt agtcagtgcc
      661 cagcctgagg ggatggcttc aaatggagca tacccagcgc tgggaccggg cgtgaccgcg
      721 aaccctggca cctccctgtc tgtgttcacg gctctgccct tcaccacacc cgctcccggc
      781 ccagcacacg ggccgctcct tgtgactgca ggggctcctc caggcggccc tctggtgctg
      841 tctaacttcc ccagcacacc tctggtgaca gaacaggatg gctgcggccc gagtggggcc
      901 ggggcttcca acgtctttgt ccagatgagg acagaggtgg ggcctgtgaa ggccgctcag
      961 gcgcagacct tggtcttaac tcagaccccc ctcgtctggc aggctccagg cgccctctgc
     1021 ggaggtgttg tgtgtccacc tcccctactc ctggcagctg ctcctgtggt gcctgttatg
     1081 gctgcccagg tggttggggg cacccaggcc tgtgagggag gctggtccca gggccttcct
     1141 cttccaccac caccaccacc ggctgcccag ctgcccccca ttgtgtccca agggaatgct
     1201 gggccatggc cacaaggggc tcacggagag ggcagcctgg cttcctccca ggccaaggcc
     1261 ccgccagatg actcctgtaa ccccaggagt gtctatgaga acttccgact ctggcagcac
     1321 tacaagcccc tggcccggag gcaccttccc cagagtcctg acaccgaagc gctttcgtgc
     1381 ttcctcatcc cagttctccg atccctggcc cggcggaagc ccaccatgac cctggaggag
     1441 ggactgtggc gggccatgcg ggaatggcag cacacgagca actttgaccg gatgatcttc
     1501 tacgagatgg cggaaaagtt cctggagttt gaggctgagg aggagatgca gattcagaaa
     1561 tcgcaatgga tgaaggggcc ccagtgcctg cctcctccag ccacaccgag gcttgaacct
     1621 cgaggacccc cggcccctga ggtggtcaag cagccagtgt accttcccag caaggccggc
     1681 cccaaggccc cgactgcctg cctgccacca cccaggcccc agaggccagt gaccaaggcc
     1741 cgccggccac caccccggcc ccaccggcga gcagagacca aggcccgcct gccaccaccc
     1801 aggccccaga gaccagcaga gaccaaggtc cctgaggaga tccccccaga agtggtgcag
     1861 gagtatgtgg acatcatgga ggagctgctg gggccttctc tcggggccac gggggagccc
     1921 gagaaacaac gggaagaggg cgaagtgaag cagccacagg aagaggactg gacgccccca
     1981 gacccgggcc tcctgagcta cactgacaag ctgtgttccc agaaagactt cgtcaccaag
     2041 gtggaggccg tcattcatcc ccaattcctg gaagaattgc tttccccaga tccacagatg
     2101 gatttcttgg ccctaagcca ggagctggag caggaggaag gactcaccct tgcccagcta
     2161 gtggagaagc gcctcctacc cttgaaggag aaacagcatg cgagggcagc ccctagtcgt
     2221 ggcacagccc ggttggactc aagttcttct aagtttgcag ctggccaagg agcagagaga
     2281 gacgtccctg acccccaaca aggggttggc atggaaacct gcccacccca gacgactgcc
     2341 cgggactctc agggacgagg cagagcacac actggcatgg ccaggtccaa agactctgtt
     2401 gtgcttttgg gatgtcagga ttcccctggg ctgagggctg cccggccaac ctctcctccc
     2461 caggaccaca gacccacctg ccctggcgtg ggtaccaagg atgccttgga tctccctgga
     2521 gggtctcctg tcagggagtc acatgggctg gctcaggggt caagtgagga ggaggaactc
     2581 cccagcctgg ccttcctctt gggttcccag cacaagcttc tgccctggtg gctaccccag
     2641 agccctgtcc ctgcctcggg ccttctcagc ccagaaaagt ggggacccca gggaactcat
     2701 cagtccccat ctgctgagag aagaggcctc aacctagcac cttctcctgc caacaaggcc
     2761 aagaagcgac ctctctttgg aagcctgtcc cctgctgaaa agacacccca cccagggcct
     2821 gggctcaggg tctctgggga gcaatccctg acttgggggc tgggtggccc ctcacagtct
     2881 caaaagagaa agggtgaccc cttggtctcc aggaaggaga agaagcagcg ttgtagccag
     2941 taggggcttc tgagcaggct ctctggggcc gatccccaag gatggggctc tggcatccga
     3001 tgccccaaag cggtcaaaag cttcttctcc cccagtgctg atcttgctgg gccttagctt
     3061 tggagggtag gggagggagg ggagggagag ggtggcctga atggggaggg caggaaggga
     3121 gggtctgggg ggaaggggct ggggagtggg ggtgggaagc agtgtgttgg gggcctcgtg
     3181 tgtaagtgtg aataaatgta gttgtcttgg aaaa
//
