LOCUS       XM_017022242           10796 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens neurotrophic receptor tyrosine kinase 3
            (NTRK3), transcript variant X4, mRNA.
ACCESSION   XM_017022242
VERSION     XM_017022242.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000015.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017022242.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10796
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
     gene            1..10796
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /note="neurotrophic receptor tyrosine kinase 3; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 22 ESTs, 36 long SRA reads, 4 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 6 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:4916"
                     /db_xref="HGNC:HGNC:8033"
                     /db_xref="MIM:191316"
     CDS             27..2279
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /codon_start=1
                     /product="NT-3 growth factor receptor isoform X3"
                     /protein_id="XP_016877731.1"
                     /db_xref="GeneID:4916"
                     /db_xref="HGNC:HGNC:8033"
                     /db_xref="MIM:191316"
                     /translation="MDVSLCPAKCSFWRIFLLGSVWLDYVGSVLACPANCVCSKTEIN
                     CRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELY
                     TGLQKLTIKNSGLRSIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQN
                     FFNCSCDIRWMQLWQEQGEAKLNSQNLYCINADGSQLPLFRMNISQCDLPEISVSHVN
                     LTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSE
                     DNGFTLTCIAENVVGMSNASVALTVYYPPRVVSLEEPELRLEHCIEFVVRGNPPPTLH
                     WLHNGQPLRESKIIHVEYYQEGEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTIN
                     GHFLKEPFPESTDNFILFDEVSPTPPITVTHKPEEDTFGVSIAVGLAAFACVLLVVLF
                     VMINKYGRRSKFGMKGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRI
                     PVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDK
                     MLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGD
                     LNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLAT
                     RNCLVGANLLVKIGDFGMSRDVYSTDYYRYTSAKALEECSDLSDRENTVKDSLYELIP
                     PDRFVPLCYH"
ORIGIN      
        1 ctctttttta gaagcagcga tcggagatgg atgtctctct ttgcccagcc aagtgtagtt
       61 tctggcggat tttcttgctg ggaagcgtct ggctggacta tgtgggctcc gtgctggctt
      121 gccctgcaaa ttgtgtctgc agcaagactg agatcaattg ccggcggccg gacgatggga
      181 acctcttccc cctcctggaa gggcaggatt cagggaacag caatgggaac gccagtatca
      241 acatcacgga catctcaagg aatatcactt ccatacacat agagaactgg cgcagtcttc
      301 acacgctcaa cgccgtggac atggagctct acaccggact tcaaaagctg accatcaaga
      361 actcaggact tcggagcatt cagcccagag cctttgccaa gaacccccat ttgcgttata
      421 taaacctgtc aagtaaccgg ctcaccacac tctcgtggca gctcttccag acgctgagtc
      481 ttcgggaatt gcagttggag cagaactttt tcaactgcag ctgtgacatc cgctggatgc
      541 agctctggca ggagcagggg gaggccaagc tcaacagcca gaacctctac tgcatcaacg
      601 ctgatggctc ccagcttcct ctcttccgca tgaacatcag tcagtgtgac cttcctgaga
      661 tcagcgtgag ccacgtcaac ctgaccgtac gagagggtga caacgctgtt atcacttgca
      721 atggctctgg atcacccctt cctgatgtgg actggatagt cactgggctg cagtccatca
      781 acactcacca gaccaatctg aactggacca atgttcatgc catcaacttg acgctggtga
      841 atgtgacgag tgaggacaat ggcttcaccc tgacgtgcat tgcagagaac gtggtgggca
      901 tgagcaatgc cagtgttgcc ctcactgtct actatccccc acgtgtggtg agcctggagg
      961 agcctgagct gcgcctggag cactgcatcg agtttgtggt gcgtggcaac cccccaccaa
     1021 cgctgcactg gctgcacaat gggcagcctc tgcgggagtc caagatcatc catgtggaat
     1081 actaccaaga gggagagatt tccgagggct gcctgctctt caacaagccc acccactaca
     1141 acaatggcaa ctataccctc attgccaaaa acccactggg cacagccaac cagaccatca
     1201 atggccactt cctcaaggag ccctttccag agagcacgga taactttatc ttgtttgacg
     1261 aagtgagtcc cacacctcct atcactgtga cccacaaacc agaagaagac acttttgggg
     1321 tatccatagc agttggactt gctgcttttg cctgtgtcct gttggtggtt ctcttcgtca
     1381 tgatcaacaa atatggtcga cggtccaaat ttggaatgaa gggtcccgtg gctgtcatca
     1441 gtggtgagga ggactcagcc agcccactgc accacatcaa ccacggcatc accacgccct
     1501 cgtcactgga tgccgggccc gacactgtgg tcattggcat gactcgcatc cctgtcattg
     1561 agaaccccca gtacttccgt cagggacaca actgccacaa gccggacacg tatgtgcagc
     1621 acattaagag gagagacatc gtgctgaagc gagaactggg tgagggagcc tttggaaagg
     1681 tcttcctggc cgagtgctac aacctcagcc cgaccaagga caagatgctt gtggctgtga
     1741 aggccctgaa ggatcccacc ctggctgccc ggaaggattt ccagagggag gccgagctgc
     1801 tcaccaacct gcagcatgag cacattgtca agttctatgg agtgtgcggc gatggggacc
     1861 ccctcatcat ggtctttgaa tacatgaagc atggagacct gaataagttc ctcagggccc
     1921 atgggccaga tgcaatgatc cttgtggatg gacagccacg ccaggccaag ggtgagctgg
     1981 ggctctccca aatgctccac attgccagtc agatcgcctc gggtatggtg tacctggcct
     2041 cccagcactt tgtgcaccga gacctggcca ccaggaactg cctggttgga gcgaatctgc
     2101 tagtgaagat tggggacttc ggcatgtcca gagatgtcta cagcacggat tattacaggt
     2161 atacatcggc taaggccttg gaggaatgct ctgatttgtc agatcgcgag aatactgtga
     2221 aggattctct ctatgagctg atacccccgg acaggtttgt acctctctgc tatcactgat
     2281 tactgaactc atttgggcct aagagtttgt tggcttctta tgcctaacac cactaagtgc
     2341 agataatcca ggcctgtgtg tgtgtgtgtg tgtgtgtgtg tgcatacacg tgtgcttgcc
     2401 tgcccagtgc agattccaga atgtgcatat aagggcatgg ggagagatgg agataaactc
     2461 ctccttatag tctttctttt tcatttttaa tttgttaaaa cgaagaggca ccatctggct
     2521 catacataag tggtatacag acgatttaca aaggtgaact gcctaatttc ctgttacaca
     2581 tttagagaga gaaaacaaat gttcccacac cagaacacca gagcgatttg ttctctcttc
     2641 ttaagacatt cacaatgaca aacacctttt ccttctgtga atcactgact caatgcttcc
     2701 aagattacct ttacactggc tttgacaagg gtaggctttg ggtaccatta tatctttcta
     2761 agaacatcag agaacactaa gagattgata gtcaaatcta gtattaaagt tttgaatgtc
     2821 ctgaagggga gaaggttgag atttcagaat acagatgttt tcagatgttt tgatttgggg
     2881 agaggagtca atacactgag atcagggagg aatggaatga ggggggaatg ggatcctact
     2941 aatgtagagc tccaggagtg ttcctttctg ttcatcctgc tgtcctgtgt gcctgtgtgc
     3001 tgtcctgtgt gacagtacct ggcacttgtt aggcacctaa taaaagtatg aatgagtgaa
     3061 gtcagaaagg gaatttagaa ttaggaaata ggtcattcca gaccaagaga aacctagaca
     3121 gataaccaga tgctcactta ggggaggtga gcctttggag atgatgtgga atgcagctgc
     3181 aggcagcagg agcaagtctt atctaatcaa gcagtgcatt atcctgggag aatgttcaga
     3241 agaggcaaac gagtgatagt ctgagtcaag gatgacccac ttcaggttct ggtaggagac
     3301 agaacagagt gtctaggaca tgatggggta agtatgctaa aatcctgtgt gtttatgaca
     3361 cacaggtgtg ggtcataaac aggtctggca gcaggtagta aggcactgga ttctaagctg
     3421 gagattctgg gtcagggttc ccagaaactc ctagaaagac agtaacagta atccttagga
     3481 agtgggaatc atttagaaca agccaacctt actggaagaa tatttgattt tatggatgtc
     3541 ttggtgtccc catagcagat gaaaagttgt aagctcttgg acccacactg ccttggtttg
     3601 atctctgctc ctataattcc tgactgtatg accttcggca agttacttgc cctttctgtg
     3661 tcttcaactg taaaatggag ccaacatccc ctatcacacg cattttctgt aaggactaag
     3721 agttaagaaa tataaagctc ttaggatgat aaataataaa tattaattat tgtcttagtc
     3781 tgttctgtgt tgctacaaca gaataccaca gaatgggtaa tttattaaag aaagagattt
     3841 atttcttatg gttctggagg ctaggcagtt caagatcgag gggcctcatc tggtgagggc
     3901 cttcttgctg tgtcataaca tggcagaaga catcacatgg caaaagacca agaatgggcc
     3961 aaacttgctt ttatagtaaa cccgctcttg tgataacaaa cccactctca tgataacaac
     4021 attaatccat tcatgagagc agagctctca tgattaatca cctgttagag gtctcacctc
     4081 tcaacactgt tgcattgggg ttaagttttc aacagaggat ctttggagga cactttcaaa
     4141 ccctagcaat tattggagct aaaatatgaa tgctttctcc aattccaaaa tggacaaggc
     4201 ttacctagat atattagtta aggtaggcca actgctgtat caaatagata ctcagatata
     4261 taatggttcc aacacaaata gaagctcatt tctaggtcat ctaacagtat gagtaggtga
     4321 attcactgga ggagtagtcc tctgctacac catcattcag gctcatggag ctctaccctt
     4381 ttccttgtgt ggggtccttc cttggtcatg ctaggcatct atctatgtcc caaccagcta
     4441 aaaggagaaa ctggcatgaa ggaatgtgtg tgggatgttg ttaatagacc tggcctgaaa
     4501 gtggggacta atcactttct ttcatggcaa gaacccagtt atatgacctt cctatttaaa
     4561 aaggtggctg agaaatggaa catagctgtg tcccacatag aagagaaaaa acatgaattg
     4621 tacttcatag ctggcaatct ctgccagagt taaggatgaa gaaaaactac attgtttttc
     4681 cacattccat cccagcagga aatcatccca tatccactga tttatcagga aagataggcc
     4741 aagccattct tactttgtat tgctactctg aatgtggaga gagttatttt gcaagatccc
     4801 cttttctatt ctccttgcaa actcttggtg tcccatgctt ttgtaagcaa tggaagagct
     4861 tggtcccacc tgccatcttg gtgctttgat tcatcctcca ggaaagcaga agagtaaatt
     4921 caagaaacta catcctatga attgggtgga ggaaagaaac aatgttccaa atcaaaggga
     4981 atgtaagtta atagataaga aaacacatct agaagaaaaa cagggaagaa atacaaatta
     5041 gagcaacttc tattccaaat ccatggtagt aaaggaggaa tccagaatat gtcgaaattc
     5101 taactgaagc cgtccagtat tttctaaaga agggttacat ccttgactaa aagcctgtat
     5161 tgttttccat cagcaggtca aaggatgggc ttcagaaact ctaagacttc ctaaaattat
     5221 atgagtaata ttgagtgggg tgttgtattt cattttttgt tttttgaagg ttcagggctt
     5281 ttaagaggat cctaaagata tttatggccc attgacttta ctgaaatgaa tttcccagca
     5341 tgtcagtcct gagagaacaa gacagagatc cagggactgt aacaatatga gagctctgga
     5401 gggcagcccc ctcattagtt taatgggagg acctgaggtg cagcaaagct gaggctttat
     5461 cagatgctct ctaaggtgcc ttccagtttt atgatcaaca agaacattga ctgattactc
     5521 agtcaccaga gctgagagcc tgaggctcct ctaagtcttt ttgaccagtg agttcttgcc
     5581 ttcaagtcgg gagaaactct cagatgaaag tcaagtggtt ggcagtgtac tgaagagagc
     5641 cagtggtctg tgagataact tggttttagg taattttaaa ggtaaaaaca aaagctaatg
     5701 atggtaattt gaggcaattg acttttagga tcacagggtt ccaccatgct ttctgctctt
     5761 cgttggaact ttgggaatct catttaataa gtggtacctc tcttctctgc ccagatgatg
     5821 tgtttgagcc cactgaggct gagaagccag gcagatgaag attataaagt acacttgaat
     5881 aatgatagaa ttcttactga tggtgatttc agtgtgcagc aacaatagtt tttttttttt
     5941 ttaataccaa gtcccctaat ctttatagca agattaggca ttccagctca gtcatagcag
     6001 cctggaaata ttgcagactt tgctctgcag aggcagaagt tttgctgctc attgctcctc
     6061 tttgtaggga gaagatactc atcagaaaag ggaaggggtt gtggccccat gcgcagtccc
     6121 caaaatcaga caagcttttt ctcccaagag gtgagattaa gactggagag ctctctgcat
     6181 tagacctgtt actccaataa ggtgtccctg tagttggaag cctgaaacag tgcaaagagg
     6241 aaggggtcca tcacaagtct attcatgtcc acataggcaa gcagttgcca gctacactca
     6301 gaatcatata gttccttcct ctgagaccag gagtagggag gcttgacccc tagcttaact
     6361 ggtgataaag gattagcagc taggcatact ggttcttgag ggatgctgac cctgtttgga
     6421 gagggcttat ccagatttgt ccctttggtt ttagccatta ggtactccta agtagaccca
     6481 ggcaccaatg aagaagtgat gctggctgtc aggagatgag gttcttgtac tggttgtcca
     6541 gtgaccagac tctgtttatt gtgtttgatt cttcctttgc tgtttttgaa atatcgtaat
     6601 cattctttaa ccatcgtcct atttatatag aggagaacaa tggaggagcg ttgtattcca
     6661 ttcccgagga agtggttttc ccaaattttt ataataaaat tttatttgag agtaatttta
     6721 gatgtacaga aaagttgcaa aaatagtgta gagaattccc atatatcctt cactcagttt
     6781 ttcctcctgt tggcatcgta tggaaccagg gtaccttggc aaaaaataag aaattaacag
     6841 tgacacaaat tattaactaa actacagact ttgtttggat tttaccagct tttccactaa
     6901 tgcacatttt actgtctcag gattcactct gcgataccaa accagtctta cttaagggca
     6961 gtggaactac cgtggtcaaa gcaggggtga ggggatggat cccccattgc ccacagtctc
     7021 tcctttgata ccctatgccc tcgatgcacc cttaggagcc tccaggattc catggttcaa
     7081 ttttctgcaa cagagatagg tgggctataa gaccccctcc tgcaaaacca gtcccagagg
     7141 tgctgagaaa ccctattttg tgagcaaatt ataactccag attcttacaa gaatctttta
     7201 gaactgtgca gtctggggca gccatcttca tatagcaagt ggacagggct ggagttactg
     7261 ttctctgctg gagtttagga gtctagagga aggtatggga tcttcttaaa ttcccagccc
     7321 taaaccatgc gtttgttctc ttcttcagct ttgggagagg gtgctttgtg ctaatcagga
     7381 gacgtggcca cagactggag agacttccaa gtggggctca gagctttagt tacctgagca
     7441 tctgctgtag gactgggtgt cgtgatatgc acatctcagg tgaattttga aaaacaactt
     7501 aaatgctaag acctattaag ttgtacagag ctgctgaggg aatgaacaca gaaggaggtg
     7561 tgtgggatac atttatgcta attataagta ttacaacctt atttccttga ttaaagccag
     7621 tggatctgca cactaattat ctacaaaata tcagtcactt tggaatacaa aagtctgttg
     7681 agggacaggg ctgagattta ggacatcttg gtctcagtgt cagttctgtg tccaggttcc
     7741 aaatcagaga tttcactttc atctctaaaa tctggagttt ggattccagc catatgatct
     7801 ctttggggtt ttgccttctg ttgaactaag ttctgtgtgt aataataagt gagaagaaga
     7861 cttgattttt ttaggatagg agggggacat ggccaaaggt agaataataa cgtcaaagtt
     7921 gtcttaacca gtctgtactg ttgctttgac cctagaccat agctcttcca catctcagcc
     7981 ccgttttttc cttcctgata aaataaaaaa acaaactcca gttttgaagc agactcttct
     8041 acattacctg gatctagttt agtgactgaa gtttaatttc tgctccaccc tcttcttctt
     8101 ctttgagata ttgaggataa ttgtccaaga ttcaccctgg tgggtagaag aattacctga
     8161 acagaatttc tttgtatttt tccaaggatg aggattatct aattattgct atcatctttg
     8221 cactcctata cctccaccct ttctagagca ttttatactt tatttcaata tggtggtaat
     8281 gttggggaca tctacctgca actcaggtat tctgaaaagt atagaactga atacagaaaa
     8341 gaatctggta ttttccaccc tgggacactc cggcaatctg gagagaagat gacgtggaga
     8401 gggcatgatg accaggaggt tgaggtgcaa agaaccgggc tctaacaatg aagtgatgaa
     8461 gttattttgt gaattctccc tgcagtggcc tgaggatatt agtcctggga agtgccctcc
     8521 catttttgtt tttgggctct tggcagccag tgacaaatgt gggaactaga atgcaggagt
     8581 agaagccaag aagcctagat tcagtctctc tgccatgact cctgacatgg aacagatccc
     8641 tttcttgccc aggacctgag tttctcattt gtaaagtgga catttctcat ctttcttcta
     8701 cactgtgtga ggcttttcat cttttcacaa gtactggcca caccaatagc attattgtct
     8761 gccactgcat ggaaactagg ttgagagttt gtgggatgta ctcaagtttc ctttttagat
     8821 acatccatgg ctttactgct ttttttcctg gactgggact gaaagaactg agtcccagtt
     8881 cagtcactcg gtttctttga tgacattgtc tttagatcag tgttcttaac ctcaactcta
     8941 gttaacactt ccctctcatg aggttaaatt agatgcttag tttccaaaca catttgcaca
     9001 tttgctaacc ctgtccatgt tggtttattt cctaccctca taccacattc cctagccatt
     9061 cgcaagatcc atgtgtgagg gatgggattc aattcaattc cttgtccatg tgctaagatg
     9121 aatagaacac aaggaaataa aaatctcata gggaatataa gaacagataa aaatgtgttg
     9181 ctctatcata agccaaaggg aggcaaattg tataaaaggc agttaagaat gtctaaagct
     9241 tatctaagta gaggaatggc atgggtcttg aggggttggt tggcagtctg gattaaattt
     9301 taggaagata tctccatcag agaggttagc atgagcaaag tcatggagga agcttggagg
     9361 taaggaaacc agaagaatga tctagaacgg tgtgtgattc aactggccga aactaaggat
     9421 ctatggaaga tgcatggaaa gaaatgttgg taaaggaaag accaccatgg cagcttttga
     9481 aaggccaact attttggctt aggtagtcaa tggacagtca cagaggattt gtcatctgtt
     9541 gaggtgtgaa tcaggtcatg tgtaaggaca attcataagg cagtggcatg tgggatagat
     9601 tgctggaaac taagaccata aaggcaggcc attgcactgg cccaggaaag aggcagtgag
     9661 atcctgtgcc acagtggtag ccatagagta tggaagagaa gccattagaa tccatgggct
     9721 caggactacg aactggagac tggctggtcc cacaggctca aagccacttg cagtttgtaa
     9781 ggggcaacta tgaaaacaaa caaacaaata caaaacaaaa aaaaaacaca aaaaaacagt
     9841 gaaatggagg gtcaggatgt gtcttcatcc attttgaggt gctataaaaa acacttgtgg
     9901 ctatgtaatt tataaagaaa agagatttga ttggctcata tctctgaaga ctgtgcaaga
     9961 agcatggtgc cagcatctgc ttctggtaag gacctcagga agcttccaat catggcaaag
    10021 gaggagcagg agtgtcacat ggtgagggag ggagcaagag agagaggaag gagtggtgcc
    10081 agactcttta atgactagat ctcatgggaa ctaagatgaa taactcactt actacctgga
    10141 gaatggcacc aggccattcc ctcagggatc cacccccatg attcaaacgc ctctcaccag
    10201 gccccacctc caacactggg gatcagattt ccacatgaga tttggaggtg acaaatacct
    10261 aaataaacca ggatggattt ttaaattgca tcttttaggc caccaagtcc attctgcatc
    10321 cttaaagtgt tagaaacaac ggagcagatg ccaaatcatt caattttaaa gaaatatata
    10381 gctggaagga gccttaaatg tcatctattt cacccttgag ggaccaggca gaatagcatc
    10441 aaaatcatcc cagacagatg gtttgctcac tctattccag tgcatcttct gggattccac
    10501 aggtttcctt ccttattcct ttcagctgtg ggagagggaa gctattttca gtgagagatt
    10561 tgtctttttc tttctaatta ttaacattct ttagaagtgg gaagttctca gttgtgtcta
    10621 gcgagaatcc tacctgctac aaggtaagta tgtttcatcc tatgtcctta gtggagataa
    10681 atgtggttta tgttataaaa cagacattat aagactcaga aaaactaaga agaacctcaa
    10741 tgtgaccaaa atggccctgt ggccaggtgc ggtggtttgt atctgtaatc ccagca
//
