LOCUS       NM_001012338           20018 bp    mRNA    linear   PRI 08-FEB-2025
DEFINITION  Homo sapiens neurotrophic receptor tyrosine kinase 3 (NTRK3),
            transcript variant 1, mRNA.
ACCESSION   NM_001012338
VERSION     NM_001012338.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 20018)
  AUTHORS   Lim,L.M., Lee,Y.C., Lin,T.W., Hong,Z.X., Hsu,W.C., Ke,H.L.,
            Hwang,D.Y., Chung,W.Y., Li,W.M., Lin,H.H., Kuo,H.T. and Huang,A.M.
  TITLE     NTRK3 exhibits a pro-oncogenic function in upper tract urothelial
            carcinomas
  JOURNAL   Kaohsiung J Med Sci 40 (5), 445-455 (2024)
   PUBMED   38593276
  REMARK    GeneRIF: NTRK3 exhibits a pro-oncogenic function in upper tract
            urothelial carcinomas.
REFERENCE   2  (bases 1 to 20018)
  AUTHORS   Weber,A.I., Parthasarathy,S., Borisova,E., Epifanova,E.,
            Preussner,M., Rusanova,A., Ambrozkiewicz,M.C., Bessa,P.,
            Newman,A.G., Muller,L., Schaal,H., Heyd,F. and Tarabykin,V.
  TITLE     Srsf1 and Elavl1 act antagonistically on neuronal fate choice in
            the developing neocortex by controlling TrkC receptor isoform
            expression
  JOURNAL   Nucleic Acids Res 51 (19), 10218-10237 (2023)
   PUBMED   37697438
  REMARK    GeneRIF: Srsf1 and Elavl1 act antagonistically on neuronal fate
            choice in the developing neocortex by controlling TrkC receptor
            isoform expression.
            Erratum:[Nucleic Acids Res. 2024 Feb 9;52(3):1522. doi:
            10.1093/nar/gkad1238.. PMID: 38142458]
REFERENCE   3  (bases 1 to 20018)
  AUTHORS   Klubickova,N., Mosaieby,E., Ptakova,N., Trinquet,A., Lae,M.,
            Costes-Martineau,V. and Skalova,A.
  TITLE     High-grade non-intestinal type sinonasal adenocarcinoma with
            ETV6::NTRK3 fusion, distinct from secretory carcinoma by
            immunoprofile and morphology
  JOURNAL   Virchows Arch 483 (2), 187-195 (2023)
   PUBMED   37415052
  REMARK    GeneRIF: High-grade non-intestinal type sinonasal adenocarcinoma
            with ETV6::NTRK3 fusion, distinct from secretory carcinoma by
            immunoprofile and morphology.
REFERENCE   4  (bases 1 to 20018)
  AUTHORS   Wang,H., Zhong,C., Qi,L., Fang,X. and Yuan,Y.
  TITLE     Expression and prognostic impact of NTF3 and TrkC in hepatocellular
            carcinoma
  JOURNAL   Scand J Gastroenterol 58 (11), 1309-1316 (2023)
   PUBMED   37272057
  REMARK    GeneRIF: Expression and prognostic impact of NTF3 and TrkC in
            hepatocellular carcinoma.
REFERENCE   5  (bases 1 to 20018)
  AUTHORS   Segal,D., Maier,S., Mastromarco,G.J., Qian,W.W., Nabeel-Shah,S.,
            Lee,H., Moore,G., Lacoste,J., Larsen,B., Lin,Z.Y.,
            Selvabaskaran,A., Liu,K., Smibert,C., Zhang,Z., Greenblatt,J.,
            Peng,J., Lee,H.O., Gingras,A.C. and Taipale,M.
  TITLE     A central chaperone-like role for 14-3-3 proteins in human cells
  JOURNAL   Mol Cell 83 (6), 974-993 (2023)
   PUBMED   36931259
REFERENCE   6  (bases 1 to 20018)
  AUTHORS   Guiton,M., Gunn-Moore,F.J., Glass,D.J., Geis,D.R., Yancopoulos,G.D.
            and Tavare,J.M.
  TITLE     Naturally occurring tyrosine kinase inserts block high affinity
            binding of phospholipase C gamma and Shc to TrkC and neurotrophin-3
            signaling
  JOURNAL   J Biol Chem 270 (35), 20384-20390 (1995)
   PUBMED   7657612
REFERENCE   7  (bases 1 to 20018)
  AUTHORS   Shelton,D.L., Sutherland,J., Gripp,J., Camerato,T., Armanini,M.P.,
            Phillips,H.S., Carroll,K., Spencer,S.D. and Levinson,A.D.
  TITLE     Human trks: molecular cloning, tissue distribution, and expression
            of extracellular domain immunoadhesins
  JOURNAL   J Neurosci 15 (1 Pt 2), 477-491 (1995)
   PUBMED   7823156
REFERENCE   8  (bases 1 to 20018)
  AUTHORS   McGregor,L.M., Baylin,S.B., Griffin,C.A., Hawkins,A.L. and
            Nelkin,B.D.
  TITLE     Molecular cloning of the cDNA for human TrkC (NTRK3), chromosomal
            assignment, and evidence for a splice variant
  JOURNAL   Genomics 22 (2), 267-272 (1994)
   PUBMED   7806211
REFERENCE   9  (bases 1 to 20018)
  AUTHORS   Ebendal,T.
  TITLE     Function and evolution in the NGF family and its receptors
  JOURNAL   J Neurosci Res 32 (4), 461-470 (1992)
   PUBMED   1326636
  REMARK    Review article
REFERENCE   10 (bases 1 to 20018)
  AUTHORS   Lamballe,F., Klein,R. and Barbacid,M.
  TITLE     trkC, a new member of the trk family of tyrosine protein kinases,
            is a receptor for neurotrophin-3
  JOURNAL   Cell 66 (5), 967-979 (1991)
   PUBMED   1653651
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC009711.10, AC021677.4 and
            AC011966.7.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Aug 13, 2020 this sequence version replaced NM_001012338.2.
            
            Summary: This gene encodes a member of the neurotrophic tyrosine
            receptor kinase (NTRK) family. This kinase is a membrane-bound
            receptor that, upon neurotrophin binding, phosphorylates itself and
            members of the MAPK pathway. Signalling through this kinase leads
            to cell differentiation and may play a role in the development of
            proprioceptive neurons that sense body position. Mutations in this
            gene have been associated with medulloblastomas, secretory breast
            carcinomas and other cancers. Several transcript variants encoding
            different isoforms have been found for this gene. [provided by
            RefSeq, Jul 2011].
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: S76475.1, KJ534904.1 [ECO:0000331]
            RNAseq introns       :: partial sample support SAMEA2145743,
                                    SAMEA2153980 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000629765.3/ ENSP00000485864.1
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-96                AC009711.10        38815-38910
            97-299              AC009711.10        39068-39270
            300-562             AC009711.10        39386-39648
            563-637             AC009711.10        111255-111329
            638-709             AC009711.10        112065-112136
            710-778             AC009711.10        148151-148219
            779-936             AC009711.10        157993-158150
            937-1079            AC009711.10        158945-159087
            1080-1221           AC009711.10        159514-159655
            1222-1518           AC009711.10        160157-160453
            1519-1542           AC009711.10        166820-166843
            1543-1607           AC021677.4         176990-177054       c
            1608-1710           AC021677.4         176099-176201       c
            1711-1899           AC021677.4         82685-82873         c
            1900-2030           AC011966.7         156312-156442       c
            2031-2203           AC011966.7         148701-148873       c
            2204-2447           AC011966.7         144880-145123       c
            2448-2489           AC011966.7         101383-101424       c
            2490-2648           AC011966.7         95959-96117         c
            2649-20018          AC011966.7         75440-92809         c
FEATURES             Location/Qualifiers
     source          1..20018
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q25.3"
     gene            1..20018
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /note="neurotrophic receptor tyrosine kinase 3"
                     /db_xref="GeneID:4916"
                     /db_xref="HGNC:HGNC:8033"
                     /db_xref="MIM:191316"
     exon            1..96
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            97..299
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            300..562
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     CDS             315..2834
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /EC_number="2.7.10.1"
                     /note="isoform a precursor is encoded by transcript
                     variant 1; tyrosine kinase receptor C; NT-3 growth factor
                     receptor; ETV6-NTRK3 fusion; ETS related
                     protein-neurotrophic receptor tyrosine kinase fusion
                     protein; neurotrophic tyrosine kinase, receptor, type 3"
                     /codon_start=1
                     /product="NT-3 growth factor receptor isoform a precursor"
                     /protein_id="NP_001012338.1"
                     /db_xref="CCDS:CCDS32322.1"
                     /db_xref="GeneID:4916"
                     /db_xref="HGNC:HGNC:8033"
                     /db_xref="MIM:191316"
                     /translation="MDVSLCPAKCSFWRIFLLGSVWLDYVGSVLACPANCVCSKTEIN
                     CRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELY
                     TGLQKLTIKNSGLRSIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQN
                     FFNCSCDIRWMQLWQEQGEAKLNSQNLYCINADGSQLPLFRMNISQCDLPEISVSHVN
                     LTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSE
                     DNGFTLTCIAENVVGMSNASVALTVYYPPRVVSLEEPELRLEHCIEFVVRGNPPPTLH
                     WLHNGQPLRESKIIHVEYYQEGEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTIN
                     GHFLKEPFPESTDNFILFDEVSPTPPITVTHKPEEDTFGVSIAVGLAAFACVLLVVLF
                     VMINKYGRRSKFGMKGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRI
                     PVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDK
                     MLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGD
                     LNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLAT
                     RNCLVGANLLVKIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPE
                     SIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKE
                     VYDVMLGCWQREPQQRLNIKEIYKILHALGKATPIYLDILG"
     exon            563..637
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            638..709
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            710..778
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            779..936
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            937..1079
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1221
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            1222..1518
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            1519..1542
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            1543..1607
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            1608..1710
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            1711..1899
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            1900..2030
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            2031..2203
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            2204..2447
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            2448..2489
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            2490..2648
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     exon            2649..20018
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /inference="alignment:Splign:2.1.0"
     regulatory      19999..20004
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /note="hexamer: AATAAA"
     polyA_site      20018
                     /gene="NTRK3"
                     /gene_synonym="gp145(trkC); GP145-TrkC; TRKC"
                     /note="major polyA site"
ORIGIN      
        1 gcacttgtac atttctgcag ccgcgcggcg agccattcgc ggcggctgct gcagctccta
       61 ctgcatcttc cttctcttcc tttcctcggg ctccggtctc ggagtcggag agcgcgcctc
      121 gcttccagag cccccggacc cggcgagtca gcgatcgccg agccggccac catgcccggc
      181 agaccgcgcc actaggcgct cctcgcggct cccacccggc ggcggcggcg gcggcggcgg
      241 cgtccgcgat ggtttcagac gctgaaggat tttgcatctg atcgctcggc gtttcaaaga
      301 agcagcgatc ggagatggat gtctctcttt gcccagccaa gtgtagtttc tggcggattt
      361 tcttgctggg aagcgtctgg ctggactatg tgggctccgt gctggcttgc cctgcaaatt
      421 gtgtctgcag caagactgag atcaattgcc ggcggccgga cgatgggaac ctcttccccc
      481 tcctggaagg gcaggattca gggaacagca atgggaacgc cagtatcaac atcacggaca
      541 tctcaaggaa tatcacttcc atacacatag agaactggcg cagtcttcac acgctcaacg
      601 ccgtggacat ggagctctac accggacttc aaaagctgac catcaagaac tcaggacttc
      661 ggagcattca gcccagagcc tttgccaaga acccccattt gcgttatata aacctgtcaa
      721 gtaaccggct caccacactc tcgtggcagc tcttccagac gctgagtctt cgggaattgc
      781 agttggagca gaactttttc aactgcagct gtgacatccg ctggatgcag ctctggcagg
      841 agcaggggga ggccaagctc aacagccaga acctctactg catcaacgct gatggctccc
      901 agcttcctct cttccgcatg aacatcagtc agtgtgacct tcctgagatc agcgtgagcc
      961 acgtcaacct gaccgtacga gagggtgaca acgctgttat cacttgcaat ggctctggat
     1021 caccccttcc tgatgtggac tggatagtca ctgggctgca gtccatcaac actcaccaga
     1081 ccaatctgaa ctggaccaat gttcatgcca tcaacttgac gctggtgaat gtgacgagtg
     1141 aggacaatgg cttcaccctg acgtgcattg cagagaacgt ggtgggcatg agcaatgcca
     1201 gtgttgccct cactgtctac tatcccccac gtgtggtgag cctggaggag cctgagctgc
     1261 gcctggagca ctgcatcgag tttgtggtgc gtggcaaccc cccaccaacg ctgcactggc
     1321 tgcacaatgg gcagcctctg cgggagtcca agatcatcca tgtggaatac taccaagagg
     1381 gagagatttc cgagggctgc ctgctcttca acaagcccac ccactacaac aatggcaact
     1441 ataccctcat tgccaaaaac ccactgggca cagccaacca gaccatcaat ggccacttcc
     1501 tcaaggagcc ctttccagag agcacggata actttatctt gtttgacgaa gtgagtccca
     1561 cacctcctat cactgtgacc cacaaaccag aagaagacac ttttggggta tccatagcag
     1621 ttggacttgc tgcttttgcc tgtgtcctgt tggtggttct cttcgtcatg atcaacaaat
     1681 atggtcgacg gtccaaattt ggaatgaagg gtcccgtggc tgtcatcagt ggtgaggagg
     1741 actcagccag cccactgcac cacatcaacc acggcatcac cacgccctcg tcactggatg
     1801 ccgggcccga cactgtggtc attggcatga ctcgcatccc tgtcattgag aacccccagt
     1861 acttccgtca gggacacaac tgccacaagc cggacacgta tgtgcagcac attaagagga
     1921 gagacatcgt gctgaagcga gaactgggtg agggagcctt tggaaaggtc ttcctggccg
     1981 agtgctacaa cctcagcccg accaaggaca agatgcttgt ggctgtgaag gccctgaagg
     2041 atcccaccct ggctgcccgg aaggatttcc agagggaggc cgagctgctc accaacctgc
     2101 agcatgagca cattgtcaag ttctatggag tgtgcggcga tggggacccc ctcatcatgg
     2161 tctttgaata catgaagcat ggagacctga ataagttcct cagggcccat gggccagatg
     2221 caatgatcct tgtggatgga cagccacgcc aggccaaggg tgagctgggg ctctcccaaa
     2281 tgctccacat tgccagtcag atcgcctcgg gtatggtgta cctggcctcc cagcactttg
     2341 tgcaccgaga cctggccacc aggaactgcc tggttggagc gaatctgcta gtgaagattg
     2401 gggacttcgg catgtccaga gatgtctaca gcacggatta ttacaggctc tttaatccat
     2461 ctggaaatga tttttgtata tggtgtgagg tgggaggaca caccatgctc cccattcgct
     2521 ggatgcctcc tgaaagcatc atgtaccgga agttcactac agagagtgat gtatggagct
     2581 tcggggtgat cctctgggag atcttcacct atggaaagca gccatggttc caactctcaa
     2641 acacggaggt cattgagtgc attacccaag gtcgtgtttt ggagcggccc cgagtctgcc
     2701 ccaaagaggt gtacgatgtc atgctggggt gctggcagag ggaaccacag cagcggttga
     2761 acatcaagga gatctacaaa atcctccatg ctttggggaa ggccacccca atctacctgg
     2821 acattcttgg ctagtggtgg ctggtggtca tgaattcata ctctgttgcc tcctctctcc
     2881 ctgcctcaca tctcccttcc acctcacaac tccttccatc cttgactgaa gcgaacatct
     2941 tcatataaac tcaagtgcct gctacacata caacactgaa aaaaggaaaa aaaaagaaag
     3001 aaaaaaaaac cctgtaaggc agtttggcaa atatatatat atatatatat atttatatat
     3061 ctaactatct atcaatctat atctacagag agttaccttc tctagtacac agagaagctg
     3121 ctgatacaga aaaccacaag actttaacaa ctcagaaact ctaaaatatt aataatacaa
     3181 aggaaaattc cctttgactt aagctgtggc ccatgcttct aatgctacgg ctctttggag
     3241 cagaagacct ggaccatgca gagagacaat ctttgggatg agagctctgg gacgggagga
     3301 gttaaggtgg tgctcagtcg ctgctgtgtg tgtctgttac cccggaagct caccacaggc
     3361 acatgtgggg actgcatggc tgtgctcagc aaagaaatga tgcctgagca gggtccttgc
     3421 ctccacttct tccccatttc ctccacttca ggacaatgtt ctaatttgtc cattctaaaa
     3481 agtgtaatct tgatgctttt gggaatcaat gatggcacct acgggtaaac acagaacaga
     3541 caaccccaca acacaaaacc atgacaagag ctgacagcat ccatcctggg tgtaagcttc
     3601 ttgctggagt tgcaaaggat gtgtctttct attctcagaa cttaaagaac tggactttct
     3661 ggagtaaaag aaccacagaa gaaaaaatag ctgaaacctg aaccctgcca agacactgcc
     3721 acctgtcttt tccatcattg caaagattcc ttggcctcac ctcccacttt caggcccctg
     3781 ggaagcttag ggggttagga aacaggtccc catgttatct ttgaatgtag acacagcacg
     3841 ctttagggtt gcaatagcaa gagacttggt tgcttgtagg tcattataac gaatgccccc
     3901 tggtcctctc agtttctcat cctgcttccc tagatcctag accccacttc ctgggtctct
     3961 actgagtccc aggtaaaccc cactgccaag gaagggagcc aggtctagtg agaggctgca
     4021 gcagtgagtg tttcaggaaa gcaagcagtg gagtgggtga gagccagcag gggagaatct
     4081 acttggcacc tgtgccaggc cccttggcat tctcctcacg tttccagccc ctgggaggat
     4141 tgatgcatct gcctttgagc tgttgtgaaa acgcaggggc tgagaaatca cttttgtggg
     4201 ctggggtagg gggaagggct gaggcttctc tgggagatgt ccaatgagcg gccagtgctg
     4261 caggcttgga atcttaatga ggcctgagcc ctgaccggag agagggaagg aaacatctgt
     4321 gctggggcct gctccctctg ccccagcact ggggaatcac tgccttcctg gctgctgcca
     4381 cataccacag tggggccgac ctctgggcct ccctgtcaca tgaaacatgg aagccaacag
     4441 cctggcccca cagatctcct ctgctggaga ggagaggatg tgttcctccc aggccacggg
     4501 gcccctctgc cttgccccaa gcacagagct acctaaggga ctgacctttg ccacactgga
     4561 gctcacctcc cgggggcctc tggcctaccc ttttccctgc cagctgaaga gactgccggc
     4621 agcctggacg tcctggttag ctgaaggcag ctgaaatgtg ggcctcccta tgtggggttt
     4681 agtactgaat tatgtgtttg tggttttgct tctttttgta gacccacaaa tatttttatt
     4741 tgaatagtaa agagctgtgc tcagattgta gccatggttg ggatttggga tcaacgaggc
     4801 tggttagctg gactgggagg ggaggcaggt gagatgggaa tttggtgttg gttttctcac
     4861 tgtgctgtgc tcctagcccc tgaggacttt gcaggaaagc tgtttggatt gaccacctca
     4921 aggaactcct ttgctgtcct atgacaatta ctcctcttgt ctttccacct agaggaccgt
     4981 tatgccgggg ctgtgagttc tggctgaagc tgcacaatct ggctttgatc tgggtagcta
     5041 agaacaggtg ttcagggagg gcatggtctg gaggcgcctg agggaaaagt atcttctggt
     5101 tagaagtgaa gcaccaatgc tcctgttgct tcccttctcc catatcctct cctgaacaaa
     5161 cactgtgtgg cttctgtctt cttggctgtg tgtttcaaaa ctgatagtca ctgatgggct
     5221 gggaagaagc aggagaagaa ctgggttgga gatgggtgga aaactgggaa taaggaccat
     5281 gctatggttt tatcttcagg gcactgattc atcatggcct aatgaaagaa ggtgattcct
     5341 tgggggaaca agaagcactg aaggagaccg cagttgtcag attgctgcca ccttaggccc
     5401 acgggctttc acgctgatct tggggtcatg ttcttactgt gtccattgta agcagctggc
     5461 tgtggaagag tgccagagag agaggggcag agcagggaag ggtagcgagg gaagatatat
     5521 tactttgata tattagcctt ggcagattaa aaaaaaaaga tttattttgg agagtaaagg
     5581 aggcagaaaa tagggccatg gaaattgcag ggtacactat ggctctgggg agtgtggcat
     5641 gtactgggac acacctgtcc ctcctatatt gggacaggac tgataaggct tagtacactg
     5701 tatcttaatt tccccatctg cagaataagg ggtacacctg ctaatctctg gccccttcta
     5761 gctctgagtt cttagattct gacaacgttg tgtcactgtg ccatttttct caataccatt
     5821 ctggaatggc aggacagcct tgcataggtg gggggcagtt gccgctgaag gctcactggg
     5881 cctgggcaag gctgagttcc aataagacac tcctctcctt ctttgcccct tgtctcaaca
     5941 tttcggagtc tgaagtgtct gagacgactg taagccagga ggggagcatt tggtcggctt
     6001 cccatcctgg cattcctaca taccagaaaa gcactgtcga cggtccattt atttatttat
     6061 ttatgaagag cctaatgtga tgaaatgtgt tgtgaaatga catcctatta gccaatatgg
     6121 ccactccagt tcatttcacc ctcattttcc cataccaaag tccacctttt agaagaccat
     6181 gtcacatcgc ctctgagagc ttagctttga agtgagctct tttgtgtctt ttgatgaacg
     6241 ctccagggca cccaggctgg tctctctgcc atgccaacct caccggatcc tctcctggac
     6301 tgagtgagag tgacctgctg ttgggtgtcc accttggagt agggtgttgt ggccatggga
     6361 cctcccaatt cttctttctt tggatgtgaa cctaactctg ccctctaatg atatccctga
     6421 actctgaggg gaccttgggc atcactgaac ctcctctagt caagagacaa gaaaaaggag
     6481 gtgctgcttc ctccattcag cagatcatgc acaaattact cctagacaga ggcttcccac
     6541 ttgaggcaaa ggatctttgg tccttctggg ttcaggttga acattaatgt tcttctctag
     6601 tgatgcctac tttgcggaat acactagtgc aagtcatttt ggtgctaaat actgcagaaa
     6661 ccaacaccaa cgggagagct gtcagccagc ttctggggct gcacgagact caactcagaa
     6721 gtagaagtga gtcagccatg ccgggagagt acagggtgca ttggaagtta agtagaaaag
     6781 tggcagggtg aaaagaccag caaaatttct gattttgcta ttagttatcc acgtggcctt
     6841 ggccaaatca gcttatttct catttgagac gtttaagagg tttgtataga tatttttaga
     6901 gtccttttca tttttttaaa gctaggttct ggtcccacct gatatatatg tacttgcttg
     6961 ttaaaaataa gagatgaagt gaaagataag gaaggagacg aagaaaagtt accaatggca
     7021 aaggattgat tatagaagac aatgaaagaa ggcctggtga ctggtagatt tgaggaatat
     7081 tgtacaggga gccaggcaga caagccagag acttcatttt tatgctcttc acaggaggtc
     7141 actggcctag ccacttgcct gcgtttcacc aggctgttcc cctcagctag tcaaccttcc
     7201 ctgttcaaaa ccaacatgct aacacttggc agaaactatt ccaagatatg gagagaggcc
     7261 tgcccatctc tcatgcaggc cactggaaat caactctggg tcaaaaccga caagattttt
     7321 atcttttaat gcttattgta agaggccggg atgtttgaaa gagggcagcg tcttaagttg
     7381 cagactattc accaaagtcc ttttctattc aggaatgact aatgactttc tttgttcccc
     7441 ttttccaaac caaacagcag cagtattacc ttgactccaa agtacagtga ttgcaatgga
     7501 cagtcttgag attaagggtc tttttagtgc tttgctcgga atctggagca aggaaatgtc
     7561 tagggatgtt tgttgaatga acccacctgc cagcagtcca gagagctgtc ccaaaggccc
     7621 ctgagatgtc tattgtctgc tttggtaggg agccaacctg ctagaagact caagggcatt
     7681 tgccttagag agaaaaaaaa atggcacatt tagttccggg cttgggtgct gaagtcactg
     7741 tgtttttggc tcctgaagct ccactttctt ttttcatacc aaataaattg ttttggccaa
     7801 tatttaagga tttaaatatt taaggttttg aaggaaaatt ccaagtttat gcatcattat
     7861 taagacatca atatgggctt gggaaaatgt tttggtgttg cttaataata ctgggagtgt
     7921 cttctaaaga aagtatacat atatgtacgt tgtgtgttta tttctatata ttggattgga
     7981 atggcttcaa agaaggcctg tttgaagtca gcaaattgat ttcaatttgg gattctcttt
     8041 tagccttacc gttcttgggg ataagaaatc tggagatgaa ctggcctcag aaacattcag
     8101 gaagattacg atgggaaatc tgtcatcttg taaagttgga tcatttggtg ctctctgaac
     8161 taaattatgc tgactaacat tctgagcatc tgaaaatcat tcttcctggt tgcctgatag
     8221 atgaccacac aggagtcatt tctatcacat cttatttggg ggttggtata gacgccacca
     8281 gcactgcagg gaaaaccacc ccctaggagg ggtgagacag agagaatgtg agattttgat
     8341 cattgattgc tctttctgaa aggcactgct gaccatagta ggtgtggtga atgtttgtgt
     8401 cactgcattg ggtattagaa cttttgctct gagcatgggc tgccctaccc tgaagagctg
     8461 aatcttggct tctgacagaa gctctgcatg actcattctc ctcaagcata ttttccttat
     8521 tttcctatga aagtatctat agtttgcaac aagaactgtc tttggttcaa gtgtcagtgt
     8581 actagaatag atgcttttct gtgagacctg tggaggttgg attggggtgg ggggtgttcc
     8641 ttcaaagtac ttggaattct ttatcaaaga aataaaactc agattctctt ctttctagtt
     8701 tacttctaag ttccaaattt aaaacaagac ccagtttgac atttgcagta ggagataatg
     8761 tcttgaacca gtgagcttgg ctatctttct ttcatcatag ggaggcaggg cagtaagttg
     8821 tattaatttt tcctaatcac ccaggcaaat attgcttttt gttcagtgtc gtgacccaca
     8881 ttcatagctt gcaggggata cttctagctg acaaagctgg aagtttctaa tagaagatgt
     8941 atcaagataa cagaggtgag gaaaggcctg ttgaacatct acttctgaga atcattgagg
     9001 cactcaggtc ttgcttttca gtttagtatc ttacaaaagg agttggtttc ttctcatttt
     9061 agcaatgata aatttagaca tcttttttga aaggccaaag gtagattgag agctcaaata
     9121 cttacggtgt actctgacag tcttttattc tatttttcaa gacttatttt atatatacat
     9181 attttttatt tccataggtt attggggaac aggtagtgtt tggttacatg agtaagttct
     9241 ttggtggtga tttgtgagat tttggcacac ccatcaccca ggcagtatgc accatatttg
     9301 tagtctttta tccctcactc ccttcccaca ctttccccct gagtccgcag agtccattgt
     9361 gtcattctta taccttgaca tcctcacagc ttagctccca catatcagtg agaacgtacg
     9421 atgtttggtt ttctattcct gaattgcttc acttagaata gtggtctcca atctcaccca
     9481 ggccgcttcg aatgccatta attcattcct ttttatggat gagtagtatt ccatcataca
     9541 tatatatgtt tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtacc acagtttctt
     9601 tatctgctca ttgattgatg ggcatttggg ttgattccac tttttgcaat tgcaaattgt
     9661 gctgctataa acatatgtgt gcaagtatct ctatctctta tgtataatga cttcttttcc
     9721 tctgggcaga tacccagtaa tagggctgcg ggattactga cattctttta catgcaacat
     9781 ccctaaaacc caacaagacg tgtaaacact gaagtccaag tctgataatt attctttcat
     9841 ttaagaagaa cacatgggag tttcacatat tatttttaaa aactaatttt gtaatatgtt
     9901 aaatggtagg acacattcaa ttttttttcc tcattggaga tctgtccatg ttctgtctca
     9961 atttaatagc tacctggcat gtaactgatg cctctgagcc tacctctgga gtgaataaat
    10021 aaacgtggtc caggtgattt gatttctgcc atttgtagtg gagaagtaaa tctcagtgaa
    10081 gaagattttt tttcatattt cttctttttt ctttttcttt tggcttctat cctcctgctt
    10141 ccatgggact gacaatccag cttctcaaac tccacgaaag tcttaataca aggtgaatcc
    10201 cagagccaca aacagtttgg acttcaaaca gtgagaaaat tggaccgaat gattcggcac
    10261 acaaagcaga aaactttcat ttcctgtagg caggatggaa ttgactgtta tattaagact
    10321 tctgaagaag ccctgccctg gagtaatttc agtgctgtca gacgatgttg acatctagat
    10381 taacctctgt gcagtgaatt ttactgcaaa gctcattgag atgcatgtga tgtgtctcca
    10441 caaatcccat ctggaacccg tggtggccca ccctcagcaa ccctcctctc cccactgact
    10501 ctgctttctc tgtccataaa cttttagcct ccaggagcag aggagccgtg gctgagatct
    10561 gaccctagga gagggagttt gggccttctc tgaccatgat gctgagccag gctttctgct
    10621 tagagtgaca gagattgtca ttgtattggg tttcccctga gggaactgca aattaaggca
    10681 tgaaaaacac tctgctgatg acagtttcac agcatatctt aatgctgcac aaagtgaaat
    10741 ggtttaaaag gaattagtgt gtcctaagtc attgagccct gctctgggct ctgcaatcct
    10801 ctagggattc aagatcccat tgcaacaagg tcatgactgc gtctaggccg gacagacgga
    10861 ttctgaagga caaggtgttt gtcttttgtg caggtctttc ctatggtcct tacaagagag
    10921 gcagccacag ctcctgtttc tcccaactgg gacaaaagat gtagctgttt tctaagcact
    10981 ggtttgtcat ctctttaagg agtggttggc tccagaatga gccagactca ctctataatt
    11041 ccacattgtg gcacaacagc cacatagaac ctcaaagctg aaattgcaac ttttctgcaa
    11101 aatagggcca ttgattacat ccaaagtttt gagaaaaggc cttcaggtta gattcagtca
    11161 ccttcagact ccacagagtt gctcagcatg gttgcaggcg tctttggaaa cttacctcag
    11221 ggttttagaa tacgttaccc tgaagtctgg ataacaattt tctctgagat tttactgatt
    11281 ctaattccct ttgaaattgt ttttcctact tgcctcttgt ctttcattta aataataaga
    11341 atctccttgc atattcttag gtatttcttt aggagaattg gaagtttcca gccaaggaca
    11401 ctgtgtttat gaattggaaa gatatctttc tgggctgaaa aaggtaaaaa tcatacggag
    11461 gcaatcttga tgactttatt taaaagcaat tatcagcatt gtgttttatt ctaggtgctc
    11521 gtgctcatag tgcaaactac attcacgttt ttaattattt atgttatgat acttattcgt
    11581 gtgtacatat atgcgcacac acacacacaa aagcctccac aatcctactg gtatacaaat
    11641 ccatatgccc catttgtgtc gcttccgttg atctttgtgt gcatgcattt gcaatgaagt
    11701 gtgcatcaca tgtgtgattt cttaaagtca tctatagctc atctttcctc ttattatcga
    11761 cacataccct ttgactttct gcactttgga gctcatgaaa ttaaggcttt ttcaagggag
    11821 actacatctt gagtttcttt aaaccttcat atttaaagat aggactggtt ttcttcgaga
    11881 aacaaaaact tgattcagat tttatttaat taattaattt tctgggggaa atggtactga
    11941 atttgttcct gagtaacaaa tagtagtaag tgcaaatata aatgtgaagt agtttaagca
    12001 ggttattgaa cctatcttgt ggctgaaaca agtagtcaga tatgaagctc agacactcaa
    12061 attgaattag aacgtgaacc aaaacggtta gcatggggca ggagaagagc actgggctag
    12121 gagcaagcct gctagattgt cacttgagtg tccttagctt aatgtgggca tctgacaact
    12181 agttgcagtc ctgtgcccct ctaattccag agatggggca agccaatctg tttctcatcc
    12241 attgctcaag ttggttatca ctgaaatatt atataccatc tcaagatcct gccctgaaca
    12301 agtttgcaaa catccccccc acactgagga gtcagtccca tttttgtttt atggcagttt
    12361 atctcttgtg accctccttt ggaagctgtc caaactctga acacttgctg tccattccct
    12421 gctccccacc ccacccttta aggccaggga aaagccaggg aaagccctat tggctcatct
    12481 ccctctttcc tagcctgcac atcaaccaag cttgggattt agcctaggtt ttcagagagg
    12541 aaaacaagtg cgttctccca gccatcagta tctttccagc cccctggacc aagtgattag
    12601 tgcctcatta gcgcctcatc agttgctttt gcacaagaga ctctgggaca acaagcctat
    12661 tataatgcct cagtctgtct ttttgaagtc aaaccatcct tctggcttgg ttaggaaagg
    12721 ggagcctttc tccaaacacg ttttctttta atttcctctg ttgttttctg gctgttaact
    12781 atatggataa atggtaaaac ataattttca ttttttctag gcccctatga gagtggatat
    12841 gctatatttc tatagatgag gagttccaca tgtcagcaaa gcatttattt atttagtgaa
    12901 gtgactataa tattgacaca cagatttgca gcagcatcca aatcttgagg gggaaaaaaa
    12961 agcctttttc aatcaaatga aaccttttct gtgatggcac cagagaggtt tatatcttaa
    13021 gcacagaact gaacctgata atatgcttcc tttctagaaa caaagagata gaagaaattg
    13081 ctgaaggagc tggaagacca aaccatctat tccccaaatc attatgtatc aatagatact
    13141 tcaactctgt tccttaaatg gctctgaaaa acacaaataa ccatatttac tattaaaaac
    13201 aaattcataa tgtctaaccc aatcccttat tttaatatat atacatatta aaataatccc
    13261 atgtatatat gattattatt atatgggata tatatagttt acatatatat aggggtgtgt
    13321 gtgtatatat atatatatat ttacatatat atgtaaatgt atacttttta atgctgggga
    13381 tagttccata ttgtttcttt tcttgattcc ttctaatata ttcaatgaga tttataattt
    13441 ttttcacttt tatttcttta ggaaagagtt ggggtctatt atgaatgctt tctaggataa
    13501 aatggcaaaa cagatggaaa gtgtggtaga gggaggataa tgggaatagg aggcagagaa
    13561 cttgcacatt tctatttcct gctgagagat cttggaaaaa cattgtctgc cctttacctc
    13621 agtttcttaa catacaaaat agaactacta tcaaccccct gcatgccaca gagggttatt
    13681 tgagccctaa atgagatcat aactgttaac atactctgtg aactgtacag ggccagacaa
    13741 atagagccca ctctctgggc agttgcatac agtcttgctg ggtgctgagc tgagtgactg
    13801 agagccgctt ttgagacaca ttttgaggca tatcttccct aaatttttgc tggtgtctgt
    13861 tttttagaag ttttgccatt agcatttttt gctttgagta tctagtgatg gagaatgctc
    13921 taaaaaatac aaggagacag ggggattctt tatctatttg gcttagtcac tggaaaggga
    13981 caattagagt ttgttttcag gcttggaact ctgacatttt gtagcaaaat ggcatcttct
    14041 gctgcattta attccttgcc atcaactctt gctttcataa ggttctgtca atttcaacat
    14101 aatgctttgt aaaaatagga ctctgtgaaa ctttctctat aaatttggtg gtataactaa
    14161 tttttcaggg agcatctgaa gggataatga tttttaagtg gtaccctgtt catgccagga
    14221 ccagcatttg tacatgggaa aataatctta agatgagtga agagcaaatg ctagaccaca
    14281 cctttaatag gcccaagtgc caacaaaaat acgtgtgagt gggattccca cggagaaatg
    14341 tttctgaatg aaaatgaaac ccttgataat gaatcctgag gccagaatgc caaagtcaca
    14401 gtattctgtc atttacagcc cctaaaaaat cccaggtgtt tgtgatgaca agccactatt
    14461 ataagtactc tgtattagtg actacttggc aagtaaaatt ttctcaaatg ttatttttca
    14521 tagatctcca agcaacaatc acttgcagtg tatctgacaa aatgctatac atgattttct
    14581 aaaagtattt tgatcactcc agaaagaaat cagaataaag ctgcataccc caaatcctag
    14641 aaaattcaca aatattttgc tcaagttcag gctctctcag cttctctttt ctctttaact
    14701 tttgcctcat acagaggcaa tcttgatgac aaaagattgg gctcaatttt tgtttttctt
    14761 gtgtagaaaa gcaacacctc tgtttcggac tactgttcag tagacaaaaa gcatcccagc
    14821 tttcgaaatg agagtccaaa ttgggttacc actgagattt taaattatga tgtgaaattg
    14881 gagaaggtga actgtacagg gccagacaaa taatagagcc cactctctgg gcagttgcat
    14941 gcagtcttgc tgggtgctga gctgagagac tgagagccgc ttttgagacg tgttttgagg
    15001 catatcttcc ttaaattttt gctggtgtct gttttttaga agttttgcca ttagcatttt
    15061 tcactttgag tatctagcca tggagaatgc tctaaaaaat acaaggagac agggggatgc
    15121 tttatctatt tggcttagtc actggttcag ggtgaagttt cataatttat tctgataatc
    15181 tggaggggat gacctccttc acagtactgt taaagccttc cttgaacaag ctcatttcac
    15241 tatataactt cctaaagaca aggctgatta tttaaggatt tcagagatat catttgggga
    15301 ataactcacc aggtagagaa agtttgacct gatatgttaa caggcacaac aagaacttat
    15361 ttcaatgctt tctcaccatc tgccccttct ctgagagttt agcctttctt aggatacttc
    15421 cttttccagg ctagaaaaga ttgattgtat tcatatccca aagtaaaggc tcctccaatt
    15481 ctatcagatg tggaggcaac agaaaatgac tcatgttatt tttctctcac ttcacagcat
    15541 caagaactct tcttgtttat gtgggggcca tggtggatta gcttgaggaa ctgtcaaatt
    15601 aaaatgaaag gaaagcaagt tggggcaaga aaattctcac tctgaatgtg aaagaaaata
    15661 gcagtgttct tctctctggc aaagatttgt gtactgttgg gggaagattc atgttatttc
    15721 tcaggtagac tttacttttt gagattctgt gtgtgtgtgt gtgtgtgtgt gtgtatgtgt
    15781 gtgtgtgtgt gtgtattttg cctggtgggg ggttaaaggc agatagaatg tagttgttta
    15841 tgagtttata ctttctcttt agcataatag atgccctgtt tattttctca gaatgtgaca
    15901 ataaaattag gaaaggagag gaattcagag gcccatgttg cagttcatgg caaagtttta
    15961 cccaaatatt tccttcagaa acatttagtc atagcaagcc atataaatta ttgtctgcaa
    16021 ctggtatcag aaaaagaaat cagtaggtgg ggactgtaga ccccaatggt gcatctgttt
    16081 acaatctttc ttttccaagg ttttaaggtt catgaataac atgagggaat tttgggagag
    16141 ctaccacatc agtactttgg cacgcattaa ctgttccaca ggaaaactag ggttgcttca
    16201 gggctatttt tgtttgaaat gacacacata caaaaaaaaa aaaagacttt tggaacatgt
    16261 tttgaggcct gtcacctgaa atcagccttt gctgaaagag tatttagttt gataagcggg
    16321 atttcttgct tctcgcatcc cagagtgtaa attctgcagc gaagcctggg tgtatgtttt
    16381 cagcaccagg gacagcaaac aaccccctga attgaagggg cccgctatcc tgattgacct
    16441 cccagactag gaagggcagt tgttttgttt tcctttattt cctatctacc ggagcctcaa
    16501 cttggaagac tttattctta aggttcttac atctttcatt tattaccaag cctagcttag
    16561 ctgtctctgt cacattcttg acctcctaac aaatgggttt ggagtaacac tcccagctct
    16621 cctggctcag agaagtagaa agaaacacac tagacttcat ttgaagggca tgctttagag
    16681 taggctcccc ctacacaagt ctttataaca taccactgac ttgtaaaccc ctaaatgaag
    16741 gactgcttat acacaatcat tttcctttta acatttctgc acatttctca caatgtacaa
    16801 gtctatgttt gactcagtgt gcatctggag gcaatgtttc acagcagttg agcagaagct
    16861 atgaagtttg gggacagaaa aggtcccagt gatgctgctg ttattcattt tggagactca
    16921 ttgggggcac ttctctgatt ctcagcatcc acccttcaac cctgagtgct ctttaacagc
    16981 tgtttttgcc ttaaacaatc acaataagaa tgcaaatgac tccttgtggc attcttcagg
    17041 ccagactgaa gggtgtactg agaaaacaag ggtagcagaa gcacatgttg tcacattgct
    17101 ttgtgattgg ccagttttta tatagcacaa tgacacacag atatcatctt agagtcatca
    17161 ttgtctactc ttaactaatt gtcagcatct tctccactca tgtcaggatg aatcctgtgt
    17221 tgggaaggca agtcagtcac tgcaggtttc atcataaata ttgccttcta tctgacagat
    17281 gttagaaaac ctccattttg aatgcctctg taccatccaa ggctctgaat ttcccctata
    17341 tcttatccct ttctttccat tccctttcca tgttgcttat cataacatcc ataacattta
    17401 gtggtgtaag aaaataaggg gtttctttta ggaataaatg aggtggaaaa agtaggacag
    17461 agccagatct cagaggagca agttcagtgg aacgatgatt tctaacttgg gagtgggtct
    17521 aagatgtagc catccattcc ttccattcct tgtcctcttg agtgaatctc attccagtgc
    17581 tcacacttgc cctgcaaaaa aggccatggc acaagattct ctagattatt tgtatgaaga
    17641 ctggaggtga gcagcatcca acacctctgt tagagttctt tagaatagag gagttttgtc
    17701 ttatatttta atccaggaac cttcccatat ttaaaaagtt tagaaataat atgtacagaa
    17761 aggacctatg gggataggaa agcttaataa tacaagttat tttcccttag aacagagggg
    17821 aaggagctgc aaagtgactg ctaatggagg aacgatctgc tggctggggg aaatgtggcc
    17881 tgagactaga gatgcagagc aggcatctct agaaggagag atgatgccaa tagaagcccc
    17941 aggagggaac tggccagcga atacaatttt ataaagattc tcagtacttt ttctgaaaaa
    18001 attcctaaaa ttttcaaggg cgcgtctagc cctctgcctc tttagaggtg agctcagtgc
    18061 tacttctggg ttcttaaggc aaatgcccta caaacaccaa agtcttgtat tttccactct
    18121 cagccggcac tggctaagtg ggattttttt tttcccttcc ctaagtgaaa gggacttgtt
    18181 ttcaggagaa gtgtccttta aacatccagc taaaactgga agtaattttt tgcatgaatg
    18241 gctttttaca gctaggtcta cagcagaaca aaacttgtat taaactaagt gctactttac
    18301 atatcttatt tcaagggaaa tgaaggattt attgtcgtgt aaatgatata cactgatttg
    18361 tttcctactg gacattacat gtccctttat ctctaggctg atgttgtgca gcaaactttc
    18421 aatatctgga aaatcagctg gtacctactt cagtgcatta ttaggatatt acgttccctg
    18481 agaggaattt tgccaatgaa gtttaggtac tgttgtaact gatttccatc ccccctccct
    18541 aagcttctgt actaagtata tgtaaagcta ttatatcttg tctgatccca tgtgttcatg
    18601 tgtgtttccc aatgtttgca taaatatatt ggcaatctga agggttagct ggcttatggc
    18661 aactgctgaa caatggtatg tttggcatgt gggacacctg atacctgggc acacctgttc
    18721 tgaggccaag ctaattttac agattttgga aaagaaaaaa cagcagcaac aacaacagtg
    18781 tggcttgaat taaggaaagt ttaacaatga atacagtatt gccaagtcat catttatggg
    18841 tggagacgtt gaccacagca gttgaggtgc tttcaactgg atcttatgcc ctttatttta
    18901 atcccaattg atagttcctc atttgtattt tatgacttag aaatactcct acgtgatgct
    18961 cgtttgtttt tctcccaggc ttctggaaag tgctgatcat gattgcttcc tatcatttgg
    19021 atcccaaagt tgataactta acataagtga ctgaggtttt agtagaactg ggttttacta
    19081 atcgtatctc ctccttgagg tgctgttccc ttcattcctt tcctttatga caggtgaatg
    19141 cattggctat gctgatttta tttgcatcct ggcgagtctt ggagaatcaa tctcgttaaa
    19201 atgatgactg catttgcctt tggagaagag gtttattgtc taagtaaaac tcttatgtga
    19261 aggtgtcatt tatgtaaaaa aaaaaaaaaa ttctaacttg ataagatggc cacaggttag
    19321 aggggtgtgt tctcagttga tattaaggga tatgttgaaa aggcaagtgc ccaccctcta
    19381 ttcttcatct cacccttcct ttctccccaa cctcaaaaga aaacaaaaaa ttattttttt
    19441 aaattgtatt agtaatttat gtttaataca aaaggatgat ttaatggtat caccaaaggt
    19501 tgtttctccc attgtgcatg tccttcagtc tcggccccat acccatcacc ccattcttca
    19561 ccctcatgct tccatcccaa ggcaaacatg tgtcttcatc ggaatctatg ggtgttgaag
    19621 ttaaatgtgg gggcagagat ttaacaccat gacactaata caaatcaacc attcttcact
    19681 ttcaaatggt taatcactac aggaaggcga actcttttct tggtttttgt ttaaaaacat
    19741 tttatacata tatatgtata tatgtgtgtg tatgtatgga cataggtatg tatatgcaca
    19801 tgtacatgta tatatgtata tatccatctt caatataaat atatcataag tgagagttgt
    19861 aaatactcct tggtcatatg tctgtctttc tcatagtatc atatcttcaa tgttatgtta
    19921 acaactccat ttattgattg atgaaatcgt gtgtagacct gtatcctcct gacatagttt
    19981 atgtagggtc tcttctcaaa taaagtataa aacaacaa
//
