LOCUS       XM_047424779            4997 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens NOP2/Sun RNA methyltransferase 6 (NSUN6),
            transcript variant X9, mRNA.
ACCESSION   XM_047424779
VERSION     XM_047424779.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000010.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4997
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
     gene            1..4997
                     /gene="NSUN6"
                     /gene_synonym="4933414E04Rik; ARL5B-AS1; MRT82; NOPD1"
                     /note="NOP2/Sun RNA methyltransferase 6; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 7 ESTs, 109 long SRA reads, 3 Proteins, and
                     88% coverage of the annotated genomic feature by RNAseq
                     alignments, including 19 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:221078"
                     /db_xref="HGNC:HGNC:23529"
                     /db_xref="MIM:617199"
     CDS             3255..4625
                     /gene="NSUN6"
                     /gene_synonym="4933414E04Rik; ARL5B-AS1; MRT82; NOPD1"
                     /codon_start=1
                     /product="tRNA (cytosine(72)-C(5))-methyltransferase NSUN6
                     isoform X5"
                     /protein_id="XP_047280735.1"
                     /db_xref="GeneID:221078"
                     /db_xref="HGNC:HGNC:23529"
                     /db_xref="MIM:617199"
                     /translation="MFHKRGKKNGKFSIVTALGKQEAERKFETLLKHLSHPPSFTTVR
                     VNTHLASVQHVKNLLLDELQKFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAI
                     VGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLG
                     NGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLN
                     PQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRA
                     FCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASY
                     QPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGG
                     EGMRGAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKF
                     VKCKST"
     polyA_site      4997
                     /gene="NSUN6"
                     /gene_synonym="4933414E04Rik; ARL5B-AS1; MRT82; NOPD1"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 acttccggta ggagagtccc aaacggccag cggctgggaa tttgcggtat cgcggggggg
       61 tgggaaattt cccttggtgc gtgctccttc tgatgtcagc cttcaaaacg tttgtgggac
      121 tcccctttga tttgagtctc tgctgctagc agctgcttcc ctgacctcta aaaccaggaa
      181 agaccatagg ttctctaagt gagcagccgc cgtttgctgc tcttagaaaa ctcacagaag
      241 tgaagagtgt ttctttcctg acttattcct gttcccctag gcaggcgtgc taggggttag
      301 gagttctgcc gtgattcttc ttcattcatt tattaatcta ttcattcacg tattcattca
      361 ttggcttatg catttatgta ctcattgatt gattgatcga ttgcagacga ggtcgggctg
      421 tgttgcccag ggggactcaa tttcctgggc tcaagcgatc ttcctgcctc gacttcccaa
      481 agtggtggga ttgcaggctc agccaccgcg cccggcccct gtcgtgattc ttagttctga
      541 aaagaattga ttgggagacg agccatggaa ggcctggagc cacagagttc agttatgtga
      601 ttaataataa cacataataa taacacatag cacccctctc cattttgcca agcattaggt
      661 atgttcgtgg atcccagatc gaagtccacg cataagccaa ttcgctgtgt aattgttttc
      721 aattccactt tccatggtta ggttctagca ttgaaaagaa aagcttcaca gcctggcatg
      781 aaacgaaact gaatgtcctt gaaaccagtt gacggaggag caagcttaaa atttttttag
      841 actctgactt cagtcagatg gttggatttt aaccttggca acgtggcctt ttaacatgcc
      901 aaactcttga gttaacctgt acaaggagaa tgtatgactt acgtcctccc agtgctatgg
      961 tttaaagacc ctttaagact tagatgcagg ataatatgct ccaacgttac aacattaaag
     1021 gcaagtttca acctcctatg tagaggaaaa agaatgtact gaccctatgc aaacttaact
     1081 ttcatgacta tcagttggac cataaatgtg aataattttg tgtttgtgta agtaatggct
     1141 taaaaggaca tttttagtcc tagcttcatt atcacaaaac aaactttaga ttccgtaaca
     1201 gcttcttcaa ttgttagaca tggatgtaaa ccacattctg cttttttttt ttttttctgg
     1261 ctttcggatt tctaagaaac catttctgaa aagaacaaag catttttgta tgaagatgca
     1321 gacatttggc tgggcgctgg ggctcatgct tgtaatccca gcactttggg aggctgaggc
     1381 gggtggatca cgaagtcaag agatggagac catcctggcc aacatggtga aaccctgtct
     1441 ctactaaaaa tacaaaaatt agccgggtgt ggtggcacgc gcctgtaatc ctagctactc
     1501 aggaggctga ggcaggagaa ttgcttgaac ctgggaggca gaggttgcag ggagcagaga
     1561 tcacaccagg gcacttcagc ctggcgacag agtgagactc cgtctaaaaa aataaaaata
     1621 aaaataaaat aaagaaaatg cagagatttg aagcaaaaaa aactatagat ttcttaaaca
     1681 tttttatgat attttagaga cagtaagttt gaattatact tctactttta actaagtgga
     1741 atgaatgtat ttatttgaac atggctcttg atatttttat tggttttgtt tctttgaaat
     1801 ttcagaaaac tttagtgttg aagttttcag ttcgttaaaa tttactttta acttactttt
     1861 aacacctttc ttatgaacaa tttacctgac aatgagactg ttctaatatt ttaaaaatat
     1921 tttttcatat ttaaaagttt tgtttgctga tttggaaatc taaaattttt acaaactgga
     1981 gggaaagaaa aatagccaca attatcaaaa gtaatatgat tgattaacag aatatagttg
     2041 tgtattatct aaacagatat catgctgatg tacctatcga tctgttagaa aaaatacttt
     2101 caattacatt aggagaggca cggtggctca tgcctgtgat gctagcagtt tgggaggcca
     2161 aggcaggtgg attacttgag cccaggaatt ttagatcaac ccagacaaca tggagaaatc
     2221 ctgtctctcc aaaaaaatac aaaagttagc tggacatggt ggtgcacatg tgtagtcccg
     2281 actaatgagg tggctgaggc aagaggctca tttgagccaa ggaggtcaag actgcagtgg
     2341 gctaagatcg tgcatctgga ctccagcctg ggtgacagtg agaccctgtc tgaaccaaaa
     2401 aaaaaaaaaa aaaaaaaaaa aaggattgta actaattttc ttaagtgttc attggaaata
     2461 acttccttta attaaattgg aatcccagta aaatctctat ccagttcaac aaaatatttt
     2521 aaagagttca aggaagaaaa atgtcaaaca actcgggaat tcaaaaaata aaactataag
     2581 atgtttttaa aaggaactat tacaaactaa cttcagataa tacttggaag agctagctgt
     2641 agctgtaatt gaattcaatt tattacttat acaactctga tcaatttgtc cattgctttt
     2701 tttaaacgga gtctcactct gtcacctagg ctggagtgca gttgtgtgat ctcagctcac
     2761 tgcaacctct gcctcccggg ttcaagcagt tctcctgcct cagtctcttg agtagctggg
     2821 attacaggca tgcaccacca tgcccagtta atttttgtat ttttagtaga gatggggttt
     2881 caccatgttg gtcaggctgg tcttgaactc ctgacctcgt gatccacctg ccttggcctc
     2941 ccaaagtgct ggaagccacc attttttaac tttcctcaac ctttaaggta atgcccattg
     3001 tgattttagt ttagttgatc agtctccaga ttaggtgtga ctgatagatt tcccgtcaga
     3061 aaattctacc tgccatatgg tctgaaatca atatgatcgc cttctgtaaa tatctattga
     3121 gagaccaaca atttttgatg ctgtgggaag gatacgagca agataaagca gcgagggatt
     3181 taagtctggc aacagttgga ctgctggatt ttcagagaag tgttccccaa agcaaattat
     3241 agtgctaatt tccaatgttc cataagcgtg gcaagaaaaa tgggaagttc tcgattgtga
     3301 ctgctttagg taaacaagaa gcagaaagga agtttgaaac tttgttaaag cacctgtcac
     3361 atcctccatc atttacaact gtcagagtga atacacattt agcctcagta caacatgtga
     3421 aaaatctgtt acttgatgaa cttcagaagt ttaatggatt aagtgttcct attcttcaac
     3481 atccagacct tcaagatgtg ttacttattc ctgttattgg acccagaaag aatattaaaa
     3541 aacaacagtg tgaagccatt gttggagccc agtgtggcaa tgcagtttta agaggagccc
     3601 atgtctatgc cccaggaatt gtgtcagcat cacaatttat gaaagctgga gatgttattt
     3661 ctgtatactc tgatattaaa ggaaaatgta agaaaggagc caaagaattt gatggaacaa
     3721 aagtatttct tggaaatggg atttctgaac taagccgcaa agaaatcttc agtggattac
     3781 ctgaactgaa aggcatgggc ataagaatga cagaaccagt atatctcagc ccttcatttg
     3841 acagtgtact gccccgttac ttatttttac aaaatttgcc atctgcctta gtaagtcatg
     3901 tactaaatcc tcaacctgga gagaagattc tagacttgtg tgcagcacct ggagggaaaa
     3961 caacacacat tgcagcacta atgcatgatc agggagaagt tatagcactg gataaaatct
     4021 tcaacaaagt agaaaaaatc aaacagaatg ccttattgtt agggctgaat tccatcaggg
     4081 cattttgttt tgatggaaca aaggcggtta aacttgatat ggtggaggac acagaaggag
     4141 aacctccatt tctaccagaa tcctttgacc gaattcttct ggatgcaccc tgtagtggaa
     4201 tgggacagag accaaacatg gcctgtactt ggtctgtgaa ggaagtggca tcatatcagc
     4261 cattacagcg aaaactcttc actgcagcgg ttcagctgct gaagccagag ggtgtgctgg
     4321 tttatagcac gtgcactata acactggccg aaaatgaaga acaggttgcc tgggccctga
     4381 caaaatttcc ttgccttcag cttcagcccc aggaaccgca gattggagga gaaggaatga
     4441 ggggagctgg gctctcatgt gaacagttga aacagctgca gcgatttgat ccatcggctg
     4501 tgccattacc ggacactgac atggactctc ttagagaggc cagaagagaa gacatgttgc
     4561 gtctggctaa taaggactct ataggttttt ttattgcaaa atttgtaaaa tgcaaaagca
     4621 cataggagag ggatggatgc tcagaaatga aaattccaaa catttgctgt ctgtggtttt
     4681 ttttttttta accaaagtgt tgtcaggcca actgaatgat gatgtggttg ctatggaaac
     4741 agaaaaggct gccagctgtt ttaccaggga tccagagaca tagaggaagt agggggtggt
     4801 atgagattat attttctgtt tttaaaagat tttttttttt tatgtattta gtagagtata
     4861 aagaaaagca gatgcctata gatgtctgga gcatattttc atttgtgatc taatgtttta
     4921 atttgtaaag tgtacaagtc atttttaatg ttaaaaatta gtgaatctaa caaaaggaat
     4981 aaattagcaa tatttga
//
