LOCUS       NM_020645               3761 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens nuclear receptor interacting protein 3 (NRIP3), mRNA.
ACCESSION   NM_020645
VERSION     NM_020645.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3761)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 3761)
  AUTHORS   Balgobind,B.V., Zwaan,C.M., Meyer,C., Marschalek,R., Pieters,R.,
            Beverloo,H.B. and Van den Heuvel-Eibrink,M.M.
  TITLE     NRIP3: a novel translocation partner of MLL detected in a pediatric
            acute myeloid leukemia with complex chromosome 11 rearrangements
  JOURNAL   Haematologica 94 (7), 1033 (2009)
   PUBMED   19454493
  REMARK    GeneRIF: NRIP3 is a novel translocation partner of MLL in acute
            myeloid leukemia
REFERENCE   3  (bases 1 to 3761)
  AUTHORS   Lee,S.Y., Obata,Y., Yoshida,M., Stockert,E., Williamson,B.,
            Jungbluth,A.A., Chen,Y.T., Old,L.J. and Scanlan,M.J.
  TITLE     Immunomic analysis of human sarcoma
  JOURNAL   Proc Natl Acad Sci U S A 100 (5), 2651-2656 (2003)
   PUBMED   12601173
REFERENCE   4  (bases 1 to 3761)
  AUTHORS   Amid,C., Bahr,A., Mujica,A., Sampson,N., Bikar,S.E.,
            Winterpacht,A., Zabel,B., Hankeln,T. and Schmidt,E.R.
  TITLE     Comparative genomic sequencing reveals a strikingly similar
            architecture of a conserved syntenic region on human chromosome
            11p15.3 (including gene ST5) and mouse chromosome 7
  JOURNAL   Cytogenet Cell Genet 93 (3-4), 284-290 (2001)
   PUBMED   11528127
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA249943.1, BC008835.2 and AC026894.7.
            
            On Nov 22, 2018 this sequence version replaced NM_020645.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            transcript and genomic sequence to make the sequence consistent
            with the reference genome assembly. The extent of this RefSeq
            transcript is supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803611.213972.1,
                                           SRR1803612.214600.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000309166.8/ ENSP00000310205.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-16                DA249943.1         49-64
            17-847              BC008835.2         1-831
            848-3761            AC026894.7         4538-7451
FEATURES             Location/Qualifiers
     source          1..3761
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..3761
                     /gene="NRIP3"
                     /gene_synonym="C11orf14; NY-SAR-105"
                     /note="nuclear receptor interacting protein 3"
                     /db_xref="GeneID:56675"
                     /db_xref="HGNC:HGNC:1167"
                     /db_xref="MIM:613125"
     exon            1..240
                     /gene="NRIP3"
                     /gene_synonym="C11orf14; NY-SAR-105"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..792
                     /gene="NRIP3"
                     /gene_synonym="C11orf14; NY-SAR-105"
                     /note="sarcoma antigen NY-SAR-105"
                     /codon_start=1
                     /product="nuclear receptor-interacting protein 3"
                     /protein_id="NP_065696.1"
                     /db_xref="CCDS:CCDS31422.1"
                     /db_xref="GeneID:56675"
                     /db_xref="HGNC:HGNC:1167"
                     /db_xref="MIM:613125"
                     /translation="MFYSGLLTEGGRKETDMREAASLRQQRRMKQAVQFIHKDSADLL
                     PLDGLKKLGSSKDMQPHNILQRRLMETNLSKLRSGPRVPWASKTNKLNQAKSEGLKKS
                     EEDDMILVSCQCAGKDVKALVDTGCLYNLISLACVDRLGLKEHVKSHKHEGEKLSLPR
                     HLKVVGQIEHLVITLGSLRLDCPAAVVDDNEKNLSLGLQTLRSLKCIINLDKHRLIMG
                     KTDKEEIPFVETVSLNEDNTSEA"
     exon            241..405
                     /gene="NRIP3"
                     /gene_synonym="C11orf14; NY-SAR-105"
                     /inference="alignment:Splign:2.1.0"
     exon            406..488
                     /gene="NRIP3"
                     /gene_synonym="C11orf14; NY-SAR-105"
                     /inference="alignment:Splign:2.1.0"
     exon            489..628
                     /gene="NRIP3"
                     /gene_synonym="C11orf14; NY-SAR-105"
                     /inference="alignment:Splign:2.1.0"
     exon            629..681
                     /gene="NRIP3"
                     /gene_synonym="C11orf14; NY-SAR-105"
                     /inference="alignment:Splign:2.1.0"
     exon            682..776
                     /gene="NRIP3"
                     /gene_synonym="C11orf14; NY-SAR-105"
                     /inference="alignment:Splign:2.1.0"
     exon            777..3761
                     /gene="NRIP3"
                     /gene_synonym="C11orf14; NY-SAR-105"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3738..3743
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NRIP3"
                     /gene_synonym="C11orf14; NY-SAR-105"
                     /note="hexamer: AATAAA"
     polyA_site      3761
                     /gene="NRIP3"
                     /gene_synonym="C11orf14; NY-SAR-105"
                     /note="major polyA site"
ORIGIN      
        1 gctggaggag ctcgaggctg aggctgccgg ggggctgtgg gctaccgggc cgccggcgcc
       61 tcagcgatgt tttactcagg gctcctcact gagggcggcc gcaaggagac cgacatgcgg
      121 gaggcggcgt cactgcgaca gcagcgccgg atgaagcagg cggtgcagtt catccacaag
      181 gactccgccg acctgctgcc cctggacggc ctcaagaagc tgggctcgtc caaggacatg
      241 caacctcata atattctgca gaggcgcctc atggaaacca acctgtctaa gctccgaagc
      301 ggtccccgtg tcccttgggc ctctaagacg aacaaactca atcaggctaa gtctgagggg
      361 ctaaagaagt ctgaggagga tgacatgatt ttggtttctt gccagtgtgc tggaaaggat
      421 gtgaaagcct tggttgacac aggctgccta tataatctca tctctttggc ctgtgtggac
      481 agattgggac tcaaggagca tgtcaaatcc cacaagcatg aaggagaaaa gctttctcta
      541 ccccggcatc tcaaagtagt gggccagatt gagcacctag tgatcacact gggctccctc
      601 cgcctggact gcccagcagc tgtggttgat gacaatgaga aaaacttgtc ccttggtcta
      661 cagactctcc gatctctgaa gtgcatcata aacttggata agcaccggct gatcatgggg
      721 aagacagaca aggaagaaat cccttttgtg gagacagtct ctttgaatga agacaacact
      781 tcagaagcat aactacagcc tgcagcatgt ctgcacgtgt gcatgcatac acaccgggtt
      841 gacagataga gaaaactggg tttgaaccaa atgccgtagt gacttgctgt ggaccaagtc
      901 cttccatcta atagaagctc caggggctcc ttcccattca gacctctcta gactatagtc
      961 tatgcttaga gatcttgtct ggttatggcc attgtttttt actactttga tcacttaact
     1021 tatagacctt ttttgacact gccagtctca cttgtggcct atttctctgc ttcttccagg
     1081 aatttgcttt tattagtcaa gtataggggc tgccaggttc tgtgtctcca tagatatatg
     1141 tgcttctttt cctatagcta aatgtataat aaacaggaac ctgaccttta cctcctttca
     1201 gctgtttcaa acaggtgcca ggatacctat gtcttagaat tagagtttct tcaaattgat
     1261 tcattgattt ctcaagtatg gattatgtga aagagcccag ggacattatc cattacagtt
     1321 taactctttc atttaaaggt ccagagaggc aagtgaattg tctaagttca tatattaggt
     1381 cagtgactga agggaccaag aacgcagacc tgatttccaa gccaagactc ccatgctgcc
     1441 tcatttgtat tcaagccttt aacaggaggg caaagaggtg agaatgtgtt aaaaaaaaaa
     1501 aaaaaaaggc agagcatggg aggaatattc tctggagatg gatgctagga tgatttgggt
     1561 agctctccct cctgtgtgcc aagcccagta aaagttcctt gccccaaact gtcacattta
     1621 ggccctcatc ttggtgccta aaaacgagcg tacaaagatg aatgaaatgg tttctcactg
     1681 tgaacctctt ggaggaaagg aggaaccaca gacagaggaa tattaatccc tctctgatat
     1741 ggaattgaag gcttaagtaa atcagagtgt cactgtcaga cgttgattac tcccaagatc
     1801 cgatcagcat ttctgcccat cctattatgt gtctgtcaag gactgaagta gctggaaacc
     1861 aggagtagag aaagatgggg ggaaaaaaag agcaaggcca gaatagaagg gagtagactg
     1921 agtagaatca gttggtggag aggcctatct agataaacct ttctgggagg cagggaatga
     1981 cattttcagg cagggaattg agatgttcag ttctgtcctg atacaaggaa agaggcagag
     2041 caggagccgg caatgttaag gacaactttt tataactgcc cagtatttcc tgacccctgt
     2101 caaaggttgg ggagaataca aggtttcttg aagctttttg actggggtgt cacattaggc
     2161 acacaggtgt ctataatgga atctcccctt cagtttggtc atagaagtgc ttggacaagt
     2221 cagaaaaata gctagctgtg ggtatccctt taagatattc ccaagtctac cctgtgtcat
     2281 agcagtagtt ctcagagtgt ttgtttaaag gatcccactt tgaactttgc caagtactac
     2341 caactacctt gtctggtgtt cagcaactgc ccctactgaa cagccctttg gaactctgaa
     2401 tgatttgggc ctcacagaag ctccctaaag cctaggaact tggtgactat catttgaaca
     2461 actaggcagc catactgcag tcagttgtca tggggtcatt ccctaggccc ccttcctatc
     2521 agcctctacc taaagaagct agataggaag ctaagcacag ccatggttgg gaggctatat
     2581 ctaaagctca tgaggggtga tcccggggtt accagccttc agcactccct ctagcaacac
     2641 cccattctct tacctagcgg ggatttgtac ctttccactg aggcctctcc atgctccttc
     2701 cctacctttc atggcaatac tttggcctgc ctcttatcct ggtactaagt tgaagtaaag
     2761 ctcacccttt acttccctac ttgaaagttc tactctgagc cttgactctt agccacagtg
     2821 aggcatgttg aaggttcctg ctggtttatt cttttttttt tttttttttt agacagagtc
     2881 tcactctgtt gcccaggctg gagtgcagtg gcacgatctc ggttcactgc aagctccgcc
     2941 tcccgggttc atgccattct cctgcctcag cctcccaagt agctgggact acaggcacct
     3001 gccaccacgc ctggctaatt ttttgtattt ttagtagaga cgggtttcac cgtgttagct
     3061 aggatggtct cgatctcctg accttgtggt ccgcccacct cagcctccca aagtgctggg
     3121 attacaggcg tgagccaccg cacccggcct tcattcactt tctttaaatg cctccaagtt
     3181 gattattctc ctagctcata tctccttgat gtgcatgagg gagcactggg tctaattttt
     3241 gggggctgag aaggtaagaa ggtgaggtca gtttttccca ggagtcctaa aaaattctgg
     3301 taccttacat tgagggtgtg ggagaaaggg tgtcatagtt ctgaaaatag gcagtagcat
     3361 gaagcaccag acctgtctca ttccttatta gatgtctatc tcaaataaca gagtttgaaa
     3421 aatattggtt ttatcatttg atatttccat gcctgactcg ggaaaataac attttctgac
     3481 ttctttctat tttcttgccc tgcacagacc ctacctggta caattttcta tttcttagct
     3541 caaagtgtct atacaatggg ttgcctggta tgtcagctgc cctcactctt gtgtaataga
     3601 aatatattgc caggctgggg acgtggagga gacgaactgg attcctccct cctcctgttg
     3661 ccaggcctct ctgcattggc actttatcct ttcagtgttt ctggctgtgt tgggttcatt
     3721 tgtgagactg atgtaacaat aaagtgaaat cttcccctct g
//
