LOCUS       NM_001395253            2033 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens neuropeptide Y receptor Y4-2 (NPY4R2), transcript
            variant 2, mRNA.
ACCESSION   NM_001395253 XM_005277644
VERSION     NM_001395253.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2033)
  AUTHORS   Yan,H., Yang,J., Marasco,J., Yamaguchi,K., Brenner,S., Collins,F.
            and Karbon,W.
  TITLE     Cloning and functional expression of cDNAs encoding human and rat
            pancreatic polypeptide receptors
  JOURNAL   Proc Natl Acad Sci U S A 93 (10), 4661-4665 (1996)
   PUBMED   8643460
REFERENCE   2  (bases 1 to 2033)
  AUTHORS   Lundell,I., Blomqvist,A.G., Berglund,M.M., Schober,D.A.,
            Johnson,D., Statnick,M.A., Gadski,R.A., Gehlert,D.R. and
            Larhammar,D.
  TITLE     Cloning of a human receptor of the NPY receptor family with high
            affinity for pancreatic polypeptide and peptide YY
  JOURNAL   J Biol Chem 270 (49), 29123-29128 (1995)
   PUBMED   7493937
REFERENCE   3  (bases 1 to 2033)
  AUTHORS   Bard,J.A., Walker,M.W., Branchek,T.A. and Weinshank,R.L.
  TITLE     Cloning and functional expression of a human Y4 subtype receptor
            for pancreatic polypeptide, neuropeptide Y, and peptide YY
  JOURNAL   J Biol Chem 270 (45), 26762-26765 (1995)
   PUBMED   7592911
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC245041.3.
            
            On Jun 19, 2021 this sequence version replaced XM_005277644.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968540,
                              SAMEA2142348 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000576178.7/ ENSP00000490174.1
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, expression, longest
                                         protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-281               AC245041.3         155721-156001       c
            282-437             AC245041.3         153770-153925       c
            438-2033            AC245041.3         151139-152734       c
FEATURES             Location/Qualifiers
     source          1..2033
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q11.22"
     gene            1..2033
                     /gene="NPY4R2"
                     /gene_synonym="CH17-360D5.1; NPY4-R; NPY4R; PP1; PPYR1"
                     /note="neuropeptide Y receptor Y4-2"
                     /db_xref="GeneID:100996758"
                     /db_xref="HGNC:HGNC:52383"
     exon            1..281
                     /gene="NPY4R2"
                     /gene_synonym="CH17-360D5.1; NPY4-R; NPY4R; PP1; PPYR1"
                     /inference="alignment:Splign:2.1.0"
     exon            282..437
                     /gene="NPY4R2"
                     /gene_synonym="CH17-360D5.1; NPY4-R; NPY4R; PP1; PPYR1"
                     /inference="alignment:Splign:2.1.0"
     exon            438..2033
                     /gene="NPY4R2"
                     /gene_synonym="CH17-360D5.1; NPY4-R; NPY4R; PP1; PPYR1"
                     /inference="alignment:Splign:2.1.0"
     CDS             497..1624
                     /gene="NPY4R2"
                     /gene_synonym="CH17-360D5.1; NPY4-R; NPY4R; PP1; PPYR1"
                     /note="neuropeptide Y receptor Y42; Neuropeptide Y
                     receptor type 4; Pancreatic polypeptide receptor 1"
                     /codon_start=1
                     /product="neuropeptide Y receptor type 4-2"
                     /protein_id="NP_001382182.1"
                     /db_xref="CCDS:CCDS81459.1"
                     /db_xref="GeneID:100996758"
                     /db_xref="HGNC:HGNC:52383"
                     /translation="MNTSHLLALLLPKSPQGENRSKPLGTPYNFSEHCQDSVDVMVFI
                     VTSYSIETVVGVLGNLCLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYT
                     IMDYWIFGETLCKMSAFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGI
                     VLIWVIACVLSLPFLANSILENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFL
                     LLFQYCLPLGFILVCYARIYRRLQRQGRVFHKGTYSLRAGHMKQVNVVLVVMVVAFAV
                     LWLPLHVFNSLEDWHHEAIPICHGNLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIK
                     ALVLTCQQSAPLEESEHLPLSTVHTEVSKGSLRLSGRSNPI"
ORIGIN      
        1 actctgcacg caggcagcat cggggcagca ggagcaggtg aagcaggcgc ggctctgccc
       61 cgcgcctggt gccccctggg cacaggagtg cggccggggg cggggccgag tgggccccgg
      121 tacgaaccct ccgggaagcc gggcgcgctg cctgcccttg gcccggggcg cagagcgtca
      181 cactggatct ggggagcatc ctacccccac tgtggacctc agtctcctca cctgagacat
      241 gggcggcccc atccgcaccc tgtaagccgc aagccaagga gattcctggc ccccatcctg
      301 gattcactta actacatctc ctggtggaag ggccctggga tgtgcacttt caacatgctt
      361 ctagaatgat tctgatgttt actgaaggtt gagaactgca accctgtggg attaataatg
      421 actagagaat ctgagaggcg tcatccctca agtgtatcac ttagttcaag agtcctggaa
      481 tcttttcaca tccactatga acacctctca cctcctggcc ttgctgctcc caaaatctcc
      541 acaaggtgaa aacagaagca aacccctggg caccccatac aacttctctg aacattgcca
      601 ggattccgtg gacgtgatgg tcttcattgt cacttcctac agcattgaga ctgtcgtggg
      661 ggtcctgggt aacctctgcc tgatgtgtgt aactgtgagg cagaaggaga aagccaacgt
      721 gaccaacctg cttatcgcca acctggcctt ctctgacttc ctcatgtgcc tcctctgcca
      781 gccgctgacc gccgtctaca ccatcatgga ctactggatc tttggagaga ccctctgcaa
      841 gatgtcggcc ttcatccagt gcatgtcggt gacggtctcc atcctctcgc tcgtcctcgt
      901 ggccctggag aggcatcagc tcatcatcaa cccaacaggc tggaagccca gcatctcaca
      961 ggcctacctg gggattgtgc tcatctgggt cattgcctgt gtcctctccc tgcccttcct
     1021 ggccaacagc atcctggaga atgtcttcca caagaaccac tccaaggctc tggagttcct
     1081 ggcggataag gtggtctgta ccgagtcctg gccactggct caccaccgca ccatctacac
     1141 caccttcctg ctcctcttcc agtactgcct cccactgggc ttcatcttgg tctgttatgc
     1201 acgcatctac cggcgcctgc agaggcaggg gcgcgtgttt cacaagggca cctacagctt
     1261 gcgagctggg cacatgaagc aggtcaatgt ggtgctggtg gtgatggtgg tggcctttgc
     1321 cgtgctctgg ctgcctctgc atgtgttcaa cagcctggaa gactggcacc atgaggccat
     1381 ccccatctgc catgggaacc tcatcttctt agtgtgccac ttgcttgcca tggcctccac
     1441 ctgtgtcaac ccattcatct atggctttct caacaccaac ttcaagaagg agatcaaggc
     1501 cctggtgctg acttgccagc agagcgcccc cctggaggag tcagagcatc tgcccctgtc
     1561 cacagtacat acggaagtct ccaaagggtc cctgaggcta agtggcaggt ccaatcccat
     1621 ttaaccaggt ctaggtcttc tccctgccat gtcccttgcc aggctcttcc acttagctaa
     1681 gtgggcacac tgcaagctgg ggtggcaccc cagcattcct ggctttctgg ggtccagata
     1741 ggctggcaag agctgttttt gcatccattt gcatcgtgaa gactggcatt ttgatacttc
     1801 agctgtttgt tcctgggaga attctgagca cagattccag aggtcacagt aagccttgca
     1861 gcttgagctg aaagatgcca gagccggaga tgtctgctgg cagcaggcag ggttcattct
     1921 ggtgacacag caacagatgc ctggcctggg aacccaggga tttcacctcc accagtgaga
     1981 ccacggggcc actgtggggt gagggaagga gcgcttggag tcagagctct aga
//
