LOCUS       XM_024447561            2165 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens natriuretic peptide receptor 2 (NPR2),
            transcript variant X2, mRNA.
ACCESSION   XM_024447561
VERSION     XM_024447561.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000009.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_024447561.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2165
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
     gene            1..2165
                     /gene="NPR2"
                     /gene_synonym="AMD1; AMDM; ANPb; ANPRB; ECDM; GC-B; GCB;
                     GUC2B; GUCY2B; NPRB; NPRBi; SNSK"
                     /note="natriuretic peptide receptor 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 52 ESTs, 74 long SRA reads, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 138 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:4882"
                     /db_xref="HGNC:HGNC:7944"
                     /db_xref="MIM:108961"
     CDS             140..1879
                     /gene="NPR2"
                     /gene_synonym="AMD1; AMDM; ANPb; ANPRB; ECDM; GC-B; GCB;
                     GUC2B; GUCY2B; NPRB; NPRBi; SNSK"
                     /codon_start=1
                     /product="atrial natriuretic peptide receptor 2 isoform
                     X2"
                     /protein_id="XP_024303329.1"
                     /db_xref="GeneID:4882"
                     /db_xref="HGNC:HGNC:7944"
                     /db_xref="MIM:108961"
                     /translation="MFGVSSFLIFRKLMLEKELASMLWRIRWEELQFGNSERYHKGAG
                     SRLTLSLRGSSYGSLMTAHGKYQIFANTGHFKGNVVAIKHVNKKRIELTRQVLFELKH
                     MRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWMFRYSLINDLV
                     KGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSHALYAKKLW
                     TAPELLSGNPLPTTGMQKADVYSFGIILQEIALRSGPFYLEGLDLSPKEIVQKVRNGQ
                     RPYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFGQIKGFIRRFNKEGGTSILDNLL
                     LRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSV
                     TIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGL
                     PGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPR
                     YCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTY
                     WLLGERKGPPGLL"
ORIGIN      
        1 cctattccct gggtgaaggg ggctcctccc tcggacaatc ccccctgtgc ctttgacttg
       61 gacgacccat cctgtgataa aagtggctcc actttcaacc ctggcaattg tggctctggg
      121 cacaggaatc accttcatca tgtttggtgt ttccagcttc ctaattttcc gaaagctgat
      181 gctggagaag gagctggcta gcatgttgtg gcgtattcgc tgggaagaac tgcagtttgg
      241 caactcagag cgttatcaca aaggtgcagg cagtcgcctc acactgtcgc tgcggggatc
      301 cagttacggc tcgctcatga cagcccatgg gaaataccag atctttgcca acaccggtca
      361 cttcaaggga aatgttgtcg ccatcaaaca tgtgaataag aagcgcattg agctgacccg
      421 gcaggttctg tttgaactca aacatatgag agatgttcag ttcaaccatc tcactcgctt
      481 cattggcgcc tgcatagacc ctcccaacat ttgcattgtc actgaatact gtcctcgtgg
      541 gagtttacag gatattctag aaaatgacag catcaacttg gactggatgt ttcgttattc
      601 actcattaat gaccttgtta agggcatggc ctttctccac aacagcatta tttcatcgca
      661 tgggagtctc aagtcctcca actgtgtggt ggatagtcgt tttgtgctca aaatcacaga
      721 ctatggcctg gccagcttcc gatcaactgc tgaacctgat gacagccatg ccctctatgc
      781 caagaagctg tggactgccc cagaactgct cagtgggaac cccttgccaa ccacaggcat
      841 gcagaaggct gacgtctata gctttgggat catcctgcag gagatagcac ttcgcagtgg
      901 tcctttctac ttggagggcc tggacctcag ccccaaagag attgtccaga aggtacgaaa
      961 tggtcagcgg ccatatttcc ggccaagcat tgaccggacc caactgaatg aagagctagt
     1021 tttgctgatg gagcgatgtt gggctcagga cccagctgag cggccagact ttggacagat
     1081 taagggcttc attcggcgct ttaacaagga gggtggcacc agcatattgg acaacctcct
     1141 gctgcgcatg gaacagtatg ccaataactt ggagaagctg gtggaggaac gcacacaggc
     1201 ctatctggag gaaaaacgca aggctgaagc tctgctctac caaatcctac cccattcagt
     1261 ggcagagcag ttaaaacggg gagagactgt acaggctgag gcctttgaca gtgttaccat
     1321 ctacttcagt gacattgttg gcttcacagc attgtcagca gagagcaccc ccatgcaggt
     1381 agtgacactt cttaatgacc tgtatacctg ctttgatgcc ataattgaca actttgatgt
     1441 ctacaaggtg gagacgattg gggatgctta catggtggta tctggcctcc caggccgaaa
     1501 tggtcaacgc catgcaccag aaattgctcg tatggcccta gcattactag atgcagtttc
     1561 ttcctttcgc atccgccacc gaccccatga ccagctgagg ctacgcatag gggtccatac
     1621 tgggccagtc tgtgctgggg ttgttggcct gaagatgccc cgttattgtc tttttggaga
     1681 cacagtgaac actgcttctc gaatggagtc taatggtcaa gcgctgaaga tccatgtctc
     1741 ctctaccacc aaggatgccc tagatgagct aggatgcttc cagctagagc ttcgggggga
     1801 tgtggaaatg aagggaaaag gaaagatgcg aacatactgg ctcttaggag agcggaaagg
     1861 acctcctgga ctcctgtaaa cccccattct ttccaagtca gatagtcttc tgctgctggt
     1921 acctgggtgg gcaatggcca ccatgtctgc acacaccaga aatggacatt ttcatatgca
     1981 atggaaaaca gccacaaaaa aacctacctt atatggaagt tgtagccctc tgcagctcag
     2041 ccctgtacat atacctgtcc ctctctggct tggtcccctt cctccctact ttctgtaaat
     2101 atctgtatct aaaccagaat attttggtca aatataaaac aataataaaa aaagttctga
     2161 tgtca
//
