LOCUS       XM_017001374            2605 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens natriuretic peptide receptor 1 (NPR1),
            transcript variant X2, mRNA.
ACCESSION   XM_017001374
VERSION     XM_017001374.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017001374.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2605
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..2605
                     /gene="NPR1"
                     /gene_synonym="ANPa; ANPRA; GUC2A; GUCY2A; NPRA"
                     /note="natriuretic peptide receptor 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 16 ESTs, 57 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     31 samples with support for all annotated introns"
                     /db_xref="GeneID:4881"
                     /db_xref="HGNC:HGNC:7943"
                     /db_xref="MIM:108960"
     CDS             422..2536
                     /gene="NPR1"
                     /gene_synonym="ANPa; ANPRA; GUC2A; GUCY2A; NPRA"
                     /codon_start=1
                     /product="atrial natriuretic peptide receptor 1 isoform
                     X2"
                     /protein_id="XP_016856863.1"
                     /db_xref="GeneID:4881"
                     /db_xref="HGNC:HGNC:7943"
                     /db_xref="MIM:108960"
                     /translation="MPGPRRPAGSRLRLLLLLLLPPLLLLLRGSHAGNLTVAVVLPLA
                     NTSYPWSWARVGPAVELALAQVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAV
                     DLKWEHNPAVFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVKDEYALTTRAGP
                     SYAKLGDFVAALHRRLGWERQALMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHL
                     EFAEDDLSHYTRLLRTMPRKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIF
                     GQSLQGGQGPAPRRPWERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQLKHLAY
                     EQFNFTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGV
                     TGYLKIDSSGDRETDFSLWDMDPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPP
                     DIPKCGFDNEDPACNQDHLSTLEVLALVGSLSLLGILIVSFFIYRKMQLEKELASELW
                     RVRWEDVEPSSLERHLRSAGSRLTLSGRGSNYGSLLTTEGQFQVFAKTAYYKGNLVAV
                     KRVNRKRIELTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDIL
                     ENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKITDYGLE
                     SFRDLDPEQGHTVYATLGSLTR"
ORIGIN      
        1 acactccctg gggcaggcgc tcacgcacgc tacaaacaca cactcctctt tcctccctcg
       61 cgcgccctct ctcatccttc ttcacgaagc gctcactcgc accctttctc tctctctctc
      121 tctctctcta acacgcacgc acactcccag ttgttcacac tcgggtcctc tccagcccga
      181 cgttctcctg gcacccacct gctccgcggc gccctgcgcg cccccctcgg tcgcgcccct
      241 tgcgctctcg gcccagaccg tcgcagctac agggggcctc gagccccggg gtgagcgtcc
      301 ccgtcccgct cctgctcctt cccataggga cgcgcctgat gcctgggacc ggccgctgag
      361 cccaagggga ccgaggaggc catggtagga gcgctcgcct gctgcggtgc ccgctgaggc
      421 catgccgggg ccccggcgcc ccgctggctc ccgcctgcgc ctgctcctgc tcctgctgct
      481 gccgccgctg ctgctgctgc tccggggcag ccacgcgggc aacctgacgg tagccgtggt
      541 actgccgctg gccaatacct cgtacccctg gtcgtgggcg cgcgtgggac ccgccgtgga
      601 gctggccctg gcccaggtga aggcgcgccc cgacttgctg ccgggctgga cggtccgcac
      661 ggtgctgggc agcagcgaaa acgcgctggg cgtctgctcc gacaccgcag cgcccctggc
      721 cgcggtggac ctcaagtggg agcacaaccc cgctgtgttc ctgggccccg gctgcgtgta
      781 cgccgccgcc ccagtggggc gcttcaccgc gcactggcgg gtcccgctgc tgaccgccgg
      841 cgccccggcg ctgggcttcg gtgtcaagga cgagtatgcg ctgaccaccc gcgcggggcc
      901 cagctacgcc aagctggggg acttcgtggc ggcgctgcac cgacggctgg gctgggagcg
      961 ccaagcgctc atgctctacg cctaccggcc gggtgacgaa gagcactgct tcttcctcgt
     1021 ggaggggctg ttcatgcggg tccgcgaccg cctcaatatt acggtggacc acctggagtt
     1081 cgccgaggac gacctcagcc actacaccag gctgctgcgg accatgccgc gcaaaggccg
     1141 agttatctac atctgcagct cccctgatgc cttcagaacc ctcatgctcc tggccctgga
     1201 agctggcttg tgtggggagg actacgtttt cttccacctg gatatctttg ggcaaagcct
     1261 gcaaggtgga cagggccctg ctccccgcag gccctgggag agaggggatg ggcaggatgt
     1321 cagtgcccgc caggcctttc aggctgccaa aatcattaca tataaagacc cagataatcc
     1381 cgagtacttg gaattcctga agcagttaaa acacctggcc tatgagcagt tcaacttcac
     1441 catggaggat ggcctggtga acaccatccc agcatccttc cacgacgggc tcctgctcta
     1501 tatccaggca gtgacggaga ctctggcaca tgggggaact gttactgatg gggagaacat
     1561 cactcagcgg atgtggaacc gaagctttca aggtgtgaca ggatacctga aaattgatag
     1621 cagtggcgat cgggaaacag acttctccct ctgggatatg gatcccgaga atggtgcctt
     1681 cagggttgta ctgaactaca atgggacttc ccaagagctg gtggctgtgt cggggcgcaa
     1741 actgaactgg cccctggggt accctcctcc tgacatcccc aaatgtggct ttgacaacga
     1801 agacccagca tgcaaccaag atcacctttc caccctggag gtgctggctt tggtgggcag
     1861 cctctccttg ctcggcattc tgattgtctc cttcttcata tacaggaaga tgcagctgga
     1921 gaaggaactg gcctcggagc tgtggcgggt gcgctgggag gacgttgagc ccagtagcct
     1981 tgagaggcac ctgcggagtg caggcagccg gctgaccctg agcgggagag gctccaatta
     2041 cggctccctg ctaaccacag agggccagtt ccaagtcttt gccaagacag catattataa
     2101 gggcaacctc gtggctgtga aacgtgtgaa ccgtaaacgc attgagctga cacgaaaagt
     2161 cctgtttgaa ctgaagcata tgcgggatgt gcagaatgaa cacctgacca ggtttgtggg
     2221 agcctgcacc gaccccccca atatctgcat cctcacagag tactgtcccc gtgggagcct
     2281 gcaggacatt ctggagaatg agagcatcac cctggactgg atgttccggt actcactcac
     2341 caatgacatc gtcaagggca tgctgtttct acacaatggg gctatctgtt cccatgggaa
     2401 cctcaagtca tccaactgcg tggtagatgg gcgctttgtg ctcaagatca ccgactatgg
     2461 gctggagagc ttcagggacc tggacccaga gcaaggacac accgtttatg ccactttggg
     2521 ctccctcact cggtgactac cgacctctga cccacagaaa agctgtggac ggcccctgag
     2581 ctcctgcgaa tggcttcacc ccctg
//
