LOCUS       NM_001395931            3605 bp    mRNA    linear   PRI 12-DEC-2024
DEFINITION  Homo sapiens nuclear pore complex interacting protein family member
            B12 (NPIPB12), transcript variant 1, mRNA.
ACCESSION   NM_001395931
VERSION     NM_001395931.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3605)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 3605)
  AUTHORS   Brandenberger,R., Wei,H., Zhang,S., Lei,S., Murage,J., Fisk,G.J.,
            Li,Y., Xu,C., Fang,R., Guegler,K., Rao,M.S., Mandalam,R.,
            Lebkowski,J. and Stanton,L.W.
  TITLE     Transcriptome characterization elucidates signaling networks that
            control human ES cell growth and differentiation
  JOURNAL   Nat Biotechnol 22 (6), 707-716 (2004)
   PUBMED   15146197
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC133555.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038195.2385588.1,
                                           SRR14038192.3348055.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2147596, SAMN03267757
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000550665.6/ ENSP00000447597.2
            RefSeq Select criteria :: based on manual assertion, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-625               AC133555.3         24294-24918
            626-783             AC133555.3         25072-25229
            784-912             AC133555.3         35095-35223
            913-1012            AC133555.3         38828-38927
            1013-1208           AC133555.3         39040-39235
            1209-1269           AC133555.3         43303-43363
            1270-1305           AC133555.3         43473-43508
            1306-3605           AC133555.3         44869-47168
FEATURES             Location/Qualifiers
     source          1..3605
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p11.2"
     gene            1..3605
                     /gene="NPIPB12"
                     /note="nuclear pore complex interacting protein family
                     member B12"
                     /db_xref="GeneID:440353"
                     /db_xref="HGNC:HGNC:37491"
     exon            1..625
                     /gene="NPIPB12"
                     /inference="alignment:Splign:2.1.0"
     exon            626..783
                     /gene="NPIPB12"
                     /inference="alignment:Splign:2.1.0"
     CDS             664..3450
                     /gene="NPIPB12"
                     /note="isoform a is encoded by transcript variant 1"
                     /codon_start=1
                     /product="nuclear pore complex-interacting protein family
                     member B12 isoform a"
                     /protein_id="NP_001382860.1"
                     /db_xref="GeneID:440353"
                     /db_xref="HGNC:HGNC:37491"
                     /translation="MVKLSIVLTPQFLSHDQGQLTKELQQHVKSVTCPCEYLRKVINT
                     LADHHHRGTDFGGSPWLHVIIAFPTSYKVVITLWIVYLWVSLLKTIFWSRNGHDGSTD
                     VQQRAWRSNRRRQEGLRSICMHTKKRVSSFRGNKIGLKDVITLRRHVETKVRAKIRKR
                     KVTTKINHHDKINGKRKTARKQKMFQRAQELRRRAEDYHKCKIPPSARKALCNWVRMA
                     AAEHRHSSGLPYWPYLTAETLKNRMGHQPPPPTQQHSITDNSLSLKTPPECVLTPLPP
                     SADDNLKTPPECVLTPLPPSADDNLKTPPECLLTPLPPSADDNLKTPPECLLTPLPPS
                     ADDNLKTPPECLLTPLPPSAPPSAPPSADDNLKTRAECLLHPLPPSADDNLKTPSERQ
                     LTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNI
                     KTPAFHPQRMIISRHLPSVSSLPFHPQLHSQQMIISRYLLSVCGFRFHHQPMIISRHL
                     PSVSSLPFHPQLHPQQMIISRHLPSVCGGRFHPQRMIISRHLPSVSSLPFHPQLHPQQ
                     MIISRHLPSVCGGRFHPQRMIISRHLPSVSSLPFHPQLHPQQMIISRHLPSVCGGRFH
                     PQRMIISRHLPSVSSLPFHPQLHPQQMIISRHLPSVCGERLRGPLPPSADDNLKTPSE
                     RQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADD
                     NIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPS
                     ADDNLKTPPLATQEAEAEKPRKPKRQRAAEMEPPPEPKRRRVGDVEPSRKPKRRRAAD
                     VEPSSPEPKRRRVGDVEPSRKPKRRRAADVEPSSPEPKRRRVGDVEPSRKPKRRRAAD
                     VEPSLPEPKRRRLS"
     exon            784..912
                     /gene="NPIPB12"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1012
                     /gene="NPIPB12"
                     /inference="alignment:Splign:2.1.0"
     exon            1013..1208
                     /gene="NPIPB12"
                     /inference="alignment:Splign:2.1.0"
     exon            1209..1269
                     /gene="NPIPB12"
                     /inference="alignment:Splign:2.1.0"
     exon            1270..1305
                     /gene="NPIPB12"
                     /inference="alignment:Splign:2.1.0"
     exon            1306..3605
                     /gene="NPIPB12"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atagagcata gctggcgatc gtgtacttac actctaaggt cacctggttg cactgtggcc
       61 tcatctgtgg ctctgaaaat gaagatttgg aaggagatca tcacagctaa tgttaacaag
      121 cccctcctgt gtgccaaatc attcacccct caccacaacc gaatgagcta aggattctca
      181 ttatatatag tttatggaga gggaagtgca gacataaaga ggtgaattat cttacccaga
      241 tcacacagct gataagtggt ggaggcagaa tagaatctaa acagtgtggc tccggagccc
      301 acatgcattg attcgacaag tgtttattga gcacctgcca cggacaaggc cttgtgtgat
      361 taaatagggt tataattagt aatataaaaa tgagaaatca ctaatgcttt ttagacttaa
      421 cattttcttt ttttgtaggt ttcaggcaca gaactgtata tccaataata gtgaaatgga
      481 tcccactaat tatgacagaa atgatgatac atttaaatga cttggatgtt ttataggtat
      541 gatctcgtga aaccttgaga gaaactgaat gacgaatgaa actattgttc ctgtttcaca
      601 cagaagaaaa ctgaggttaa aaggggttgg cactcatcat gagcccctgt tctcattctg
      661 caaatggtga agctctctat tgtcctgacc ccacagttcc tgtcccatga ccagggccag
      721 ctcaccaagg agctgcagca gcatgtaaag tcagtgacat gcccatgcga gtacctgagg
      781 aaggttatca atactctggc tgaccatcat catcgtggga ctgactttgg tggaagtcct
      841 tggttacatg tcattattgc gtttccgaca agttataaag ttgtcattac cctctggata
      901 gtttaccttt gggtgtctct cctgaagact atcttctggt ctcgaaatgg acatgatgga
      961 tccacggatg tacagcagag agcctggagg tccaaccgcc gtagacagga agggctgagg
     1021 tccatttgta tgcacacaaa gaaaagagtt tcttcctttc gaggaaataa aattggcctg
     1081 aaagacgtca ttactctacg gagacatgtg gaaacaaaag ttagagctaa aatccgtaag
     1141 aggaaggtga caacgaaaat caaccatcat gacaaaatca atggaaagag gaagaccgcc
     1201 agaaaacaga aaatgtttca acgtgcgcaa gagttgcggc ggcgggcaga ggactaccac
     1261 aaatgcaaaa tccccccttc tgcaagaaag gctctttgca actgggtcag aatggcggca
     1321 gcggagcatc gtcattcttc aggattgccc tactggccct acctcacagc tgaaacttta
     1381 aaaaacagga tgggccacca gccacctcct ccaactcaac aacattctat aactgataac
     1441 tccctgagcc tcaagacacc tcccgagtgt gtgctcactc cccttccacc ctcagcggat
     1501 gataatctca agacacctcc cgagtgtgtg ctcactcccc ttccaccctc agcggatgat
     1561 aatctcaaga cacctcctga gtgtctgctc actccccttc caccctcagc ggatgataat
     1621 ctcaagacac ctcccgagtg tctgctcact ccccttccac cctcagcgga tgataatctc
     1681 aagacacctc ccgagtgtct gctcactccc cttccaccct cagctccacc ctcagctcca
     1741 ccctcagcgg atgataatct caagacacgt gccgagtgtc tgctccatcc ccttccaccc
     1801 tcagcggatg ataatctcaa gacaccttcc gagcgtcagc tcactcccct tccaccctca
     1861 gctccaccct cagcagatga taatatcaag acacctgccg agcgtctgcg ggggccgctt
     1921 ccaccctcag cggatgataa tctcaagaca ccttccgagc gtcagctcac tccccttcca
     1981 ccctcagctc caccctcagc agatgataat atcaagacac ctgccttcca ccctcagcgg
     2041 atgataatct caagacacct tccgagcgtc agctcactcc ccttccaccc tcagctccac
     2101 tctcagcaga tgataatatc aagatacctg ctgagcgtct gcggattccg cttccaccat
     2161 cagccgatga taatctcaag acaccttccg agcgtcagct cactcccctt ccaccctcag
     2221 ctccaccctc agcagatgat aatatcaaga cacctgccga gcgtctgcgg gggccgcttc
     2281 caccctcagc ggatgataat ctcaagacac cttccgagcg tcagctcact ccccttccac
     2341 cctcagctcc accctcagca gatgataata tcaagacacc tgccgagcgt ctgcgggggc
     2401 cgcttccacc ctcagcggat gataatctca agacaccttc cgagcgtcag ctcactcccc
     2461 ttccaccctc agctccaccc tcagcagatg ataatatcaa gacacctgcc gagcgtctgc
     2521 gggggccgct tccaccctca gcggatgata atctcaagac accttccgag cgtcagctca
     2581 ctccccttcc accctcagct ccaccctcag cagatgataa tatcaagaca cctgccgagc
     2641 gtctgcgggg agcgtctgcg ggggccgctt ccaccctcag cggatgataa tctcaagaca
     2701 ccttccgagc gtcagctcac tccccttcca ccctcagctc caccctcagc agatgataat
     2761 atcaagacac ctgccgagcg tctgcggggg ccgcttccac cctcagcgga tgataatctc
     2821 aagacacctt ccgagcgtca gctcactccc cttccaccct cagctccacc ctcagcagat
     2881 gataatatca agacacctgc cgagcgtctg cgggggccgc ttccaccctc agcggatgat
     2941 aatctcaaga caccttctga gcgtcagctc actccccttc caccctcagc tccaccctca
     3001 gcagatgata atatcaagac acctgccgag cgtctgcggg ggccgcttcc accctcagcc
     3061 gatgataatc tcaagacacc tcccttagct actcaggagg ctgaggcaga aaaaccacgc
     3121 aaacccaaga ggcagagggc ggctgagatg gaaccacctc ccgaacccaa gaggcggagg
     3181 gtcggtgacg tggaaccgtc acgcaaaccc aagaggcgga gggccgctga cgtggaacca
     3241 tcatcacccg aacccaagag gcggagggtc ggtgatgtgg aaccgtcacg caaacccaag
     3301 aggcggaggg ccgctgacgt ggaaccatca tcacccgaac ccaagaggcg gagggtcggt
     3361 gacgtggaac cgtcacgcaa acccaagagg cggagggccg ctgacgtgga accatcatta
     3421 cccgaaccca agaggcggag gttgagctga gaagaggcca gtgcactcaa gcctgagcaa
     3481 taagaataaa accgagtaga acaaaataaa aaattcaaaa aacaaaacaa aacccacact
     3541 ccaaaaacta acaaagaata aataaataat ataaaaataa aataaatact gcagtcctta
     3601 tgtta
//
