LOCUS       NM_001277325            1084 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens nuclear pore complex interacting protein family member
            A5 (NPIPA5), transcript variant 1, mRNA.
ACCESSION   NM_001277325 XM_003118698
VERSION     NM_001277325.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1084)
  AUTHORS   Hornan,D.M., Peirson,S.N., Hardcastle,A.J., Molday,R.S.,
            Cheetham,M.E. and Webster,A.R.
  TITLE     Novel retinal and cone photoreceptor transcripts revealed by human
            macular expression profiling
  JOURNAL   Invest Ophthalmol Vis Sci 48 (12), 5388-5396 (2007)
   PUBMED   18055785
REFERENCE   2  (bases 1 to 1084)
  AUTHORS   Wang,A.G., Yoon,S.Y., Oh,J.H., Jeon,Y.J., Kim,M., Kim,J.M.,
            Byun,S.S., Yang,J.O., Kim,J.H., Kim,D.G., Yeom,Y.I., Yoo,H.S.,
            Kim,Y.S. and Kim,N.S.
  TITLE     Identification of intrahepatic cholangiocarcinoma related genes by
            comparison with normal liver tissues using expressed sequence tags
  JOURNAL   Biochem Biophys Res Commun 345 (3), 1022-1032 (2006)
   PUBMED   16712791
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            EL734608.1, CB123100.1 and AC137803.2.
            This sequence is a reference standard in the RefSeqGene project.
            
            On May 17, 2019 this sequence version replaced NM_001277325.1.
            
            Transcript Variant: This variant (1) represents the shorter
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The exon combination of this
            transcript is inferred based on paralogous transcript alignments.
            
            CCDS Note: This gene is one of several nuclear pore complex
            interacting protein (NPIP) gene copies that are present on
            chromosome 16. There are no full-length transcripts derived from
            this gene copy in support of this CCDS representation, and thus its
            exon combination is inferred based on paralogous transcript
            alignments, e.g., the mRNA AF132984.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KF175170.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1966682, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000360151.9/ ENSP00000433597.1
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-322               EL734608.1         1-322
            323-738             CB123100.1         1-416
            739-1084            AC137803.2         43131-43476
FEATURES             Location/Qualifiers
     source          1..1084
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p13.11"
     gene            1..1084
                     /gene="NPIPA5"
                     /gene_synonym="NPIP"
                     /note="nuclear pore complex interacting protein family
                     member A5"
                     /db_xref="GeneID:100288332"
                     /db_xref="HGNC:HGNC:41980"
     CDS             1..1053
                     /gene="NPIPA5"
                     /gene_synonym="NPIP"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="nuclear pore complex-interacting protein family
                     member A5 isoform 1"
                     /protein_id="NP_001264254.1"
                     /db_xref="CCDS:CCDS59264.1"
                     /db_xref="GeneID:100288332"
                     /db_xref="HGNC:HGNC:41980"
                     /translation="MFCCLGYEWLSGGCKTWHSAWVINTLADHRHRGTDFGGSPWLLI
                     ITVFLRSYKFAISLCTSYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNCRRQEGIKIV
                     LEDIFTLWRQVETKVRAKIRKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHGEK
                     ERQVSEAEENGKLDMKEIHTYMEMFQRAQALRRRAEDYYRCKITPSARKPLCNRVRMA
                     AVEHRHSSGLPYWPYLTAETLKNRMGHQPPPPTQQHSIIDNSLSLKTPSERLLYPLPP
                     SADDNLKTPPECLLTPLPPSALPSADDNLKTPAECLLTPLPPSAPPSADDNLKTPPEC
                     VCSLPFHPQRMIISRN"
     exon            1..63
                     /gene="NPIPA5"
                     /gene_synonym="NPIP"
                     /inference="alignment:Splign:2.1.0"
     exon            64..192
                     /gene="NPIPA5"
                     /gene_synonym="NPIP"
                     /inference="alignment:Splign:2.1.0"
     exon            193..292
                     /gene="NPIPA5"
                     /gene_synonym="NPIP"
                     /inference="alignment:Splign:2.1.0"
     exon            293..437
                     /gene="NPIPA5"
                     /gene_synonym="NPIP"
                     /inference="alignment:Splign:2.1.0"
     exon            438..545
                     /gene="NPIPA5"
                     /gene_synonym="NPIP"
                     /inference="alignment:Splign:2.1.0"
     exon            546..606
                     /gene="NPIPA5"
                     /gene_synonym="NPIP"
                     /inference="alignment:Splign:2.1.0"
     exon            607..642
                     /gene="NPIPA5"
                     /gene_synonym="NPIP"
                     /inference="alignment:Splign:2.1.0"
     exon            643..1084
                     /gene="NPIPA5"
                     /gene_synonym="NPIP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1067..1072
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NPIPA5"
                     /gene_synonym="NPIP"
                     /note="hexamer: AATAAT"
     polyA_site      1084
                     /gene="NPIPA5"
                     /gene_synonym="NPIP"
                     /note="major polyA site"
ORIGIN      
        1 atgttttgtt gcttaggata tgaatggctg agcggaggct gtaaaacctg gcactctgct
       61 tgggttatca atactctggc tgaccatcgt catcgtggga ctgactttgg tggaagtcct
      121 tggttactta tcattactgt gtttctgaga agttataaat ttgccatctc cctctgcaca
      181 agttaccttt gtgtgtcttt cctgaagact atcttcccgt ctcaaaatgg acatgatgga
      241 tccacggatg tacagcagag agccaggagg tccaactgcc gtagacagga aggaattaaa
      301 attgtcctgg aagacatctt tactttatgg agacaggtgg aaaccaaagt tcgagctaaa
      361 atccgtaaga tgaaggtgac aacaaaagtc aaccgtcatg acaaaatcaa tggaaagagg
      421 aagaccgcca aagaacatct gaggaaacta agcatgaaag aacgtgagca cggagaaaag
      481 gagaggcagg tgtcagaggc agaggaaaat gggaaattgg atatgaaaga aatacacacc
      541 tacatggaaa tgtttcaacg tgcgcaagcg ttgcggcggc gggcagagga ctactacaga
      601 tgcaaaatca ccccttctgc aagaaagcct ctttgcaacc gggtcagaat ggcggcagtg
      661 gagcatcgtc attcttcagg attgccctac tggccctacc tcacagctga aactttaaaa
      721 aacaggatgg gccaccagcc acctcctcca actcaacaac attctataat tgataactcc
      781 ctgagcctca agacaccttc cgagcgtctg ctctatcccc ttccaccctc agcggatgat
      841 aatctcaaga cacctcccga gtgtctgctc actccccttc caccctcagc tctaccctca
      901 gcggatgata atctcaagac acctgccgag tgtctgctca ctccccttcc accctcagct
      961 ccaccctcag cggatgataa tctcaagaca cctcccgagt gtgtctgctc actccccttc
     1021 caccctcagc ggatgataat ctcaagaaac taatgaagaa taaataaata atataaaaat
     1081 aaaa
//
