LOCUS       NM_006985               1084 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens nuclear pore complex interacting protein family member
            A1 (NPIPA1), mRNA.
ACCESSION   NM_006985 XM_003403681
VERSION     NM_006985.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1084)
  AUTHORS   Hornan,D.M., Peirson,S.N., Hardcastle,A.J., Molday,R.S.,
            Cheetham,M.E. and Webster,A.R.
  TITLE     Novel retinal and cone photoreceptor transcripts revealed by human
            macular expression profiling
  JOURNAL   Invest Ophthalmol Vis Sci 48 (12), 5388-5396 (2007)
   PUBMED   18055785
REFERENCE   2  (bases 1 to 1084)
  AUTHORS   Johnson,M.E., Viggiano,L., Bailey,J.A., Abdul-Rauf,M., Goodwin,G.,
            Rocchi,M. and Eichler,E.E.
  TITLE     Positive selection of a gene family during the emergence of humans
            and African apes
  JOURNAL   Nature 413 (6855), 514-519 (2001)
   PUBMED   11586358
REFERENCE   3  (bases 1 to 1084)
  AUTHORS   Loftus,B.J., Kim,U.J., Sneddon,V.P., Kalush,F., Brandon,R.,
            Fuhrmann,J., Mason,T., Crosby,M.L., Barnstead,M., Cronin,L.,
            Deslattes Mays,A., Cao,Y., Xu,R.X., Kang,H.L., Mitchell,S.,
            Eichler,E.E., Harris,P.C., Venter,J.C. and Adams,M.D.
  TITLE     Genome duplications and other features in 12 Mb of DNA sequence
            from human chromosome 16p and 16q
  JOURNAL   Genomics 60 (3), 295-308 (1999)
   PUBMED   10493829
REFERENCE   4  (bases 1 to 1084)
  AUTHORS   Cotlier,E., Baskin,M. and Kresca,L.
  TITLE     Effects of lysophosphatidyl choline and phospholipase A on the lens
  JOURNAL   Invest Ophthalmol 14 (9), 697-701 (1975)
   PUBMED   1158635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            KF175225.1 and AC138932.4.
            
            On May 17, 2019 this sequence version replaced NM_006985.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF132984.1, KF175225.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000328085.10/ ENSP00000331843.6
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-181               KF175225.1         1-181
            182-182             AC138932.4         97237-97237         c
            183-970             KF175225.1         183-970
            971-1084            AC138932.4         87111-87224         c
FEATURES             Location/Qualifiers
     source          1..1084
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p13.11"
     gene            1..1084
                     /gene="NPIPA1"
                     /gene_synonym="morpheus; NPIP; NPIPA"
                     /note="nuclear pore complex interacting protein family
                     member A1"
                     /db_xref="GeneID:9284"
                     /db_xref="HGNC:HGNC:7909"
                     /db_xref="MIM:606406"
     CDS             1..1053
                     /gene="NPIPA1"
                     /gene_synonym="morpheus; NPIP; NPIPA"
                     /note="nuclear pore complex-interacting protein A type"
                     /codon_start=1
                     /product="nuclear pore complex-interacting protein family
                     member A1"
                     /protein_id="NP_008916.2"
                     /db_xref="CCDS:CCDS10557.1"
                     /db_xref="GeneID:9284"
                     /db_xref="HGNC:HGNC:7909"
                     /db_xref="MIM:606406"
                     /translation="MFCCLGYEWLSGGCKTWHSAWVINTLADHRHRGTDFGGSPWLLI
                     ITVFLRSYKFAISLCTSYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEGIKIV
                     LEDIFTLWRQVETKVRAKIRKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHGEK
                     ERQVSEAEENGKLDMKEIHTYMEMFQRAQALRRRAEDYYRCKITPSARKPLCNRVRMA
                     AVEHRHSSGLPYWPYLTAETLKNRMGHQPPPPTQQHSIIDNSLSLKTPSECLLTPLPP
                     SALPSADDNLKTPAECLLYPLPPSADDNLKTPPECLLTPLPPSAPPSVDDNLKTPPEC
                     VCSLPFHPQRMIISRN"
     exon            1..63
                     /gene="NPIPA1"
                     /gene_synonym="morpheus; NPIP; NPIPA"
                     /inference="alignment:Splign:2.1.0"
     exon            64..192
                     /gene="NPIPA1"
                     /gene_synonym="morpheus; NPIP; NPIPA"
                     /inference="alignment:Splign:2.1.0"
     exon            193..292
                     /gene="NPIPA1"
                     /gene_synonym="morpheus; NPIP; NPIPA"
                     /inference="alignment:Splign:2.1.0"
     exon            293..437
                     /gene="NPIPA1"
                     /gene_synonym="morpheus; NPIP; NPIPA"
                     /inference="alignment:Splign:2.1.0"
     exon            438..545
                     /gene="NPIPA1"
                     /gene_synonym="morpheus; NPIP; NPIPA"
                     /inference="alignment:Splign:2.1.0"
     exon            546..606
                     /gene="NPIPA1"
                     /gene_synonym="morpheus; NPIP; NPIPA"
                     /inference="alignment:Splign:2.1.0"
     exon            607..642
                     /gene="NPIPA1"
                     /gene_synonym="morpheus; NPIP; NPIPA"
                     /inference="alignment:Splign:2.1.0"
     exon            643..1084
                     /gene="NPIPA1"
                     /gene_synonym="morpheus; NPIP; NPIPA"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1044..1049
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NPIPA1"
                     /gene_synonym="morpheus; NPIP; NPIPA"
                     /note="hexamer: AAGAAA"
     polyA_site      1064
                     /gene="NPIPA1"
                     /gene_synonym="morpheus; NPIP; NPIPA"
     regulatory      1067..1072
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NPIPA1"
                     /gene_synonym="morpheus; NPIP; NPIPA"
                     /note="hexamer: AATAAT"
     polyA_site      1084
                     /gene="NPIPA1"
                     /gene_synonym="morpheus; NPIP; NPIPA"
                     /note="major polyA site"
ORIGIN      
        1 atgttttgtt gcttaggata tgaatggctg agcggaggct gtaaaacctg gcactctgct
       61 tgggttatca atactctggc tgaccatcgt catcgtggga ctgactttgg tggaagtcct
      121 tggttactta tcattactgt gtttctgaga agttataaat ttgccatctc cctctgcaca
      181 agttaccttt gtgtgtcttt cctgaagact atcttcccgt ctcaaaatgg acatgatgga
      241 tccacggatg tacagcagag agccaggagg tccaaccgcc gtagacagga aggaattaaa
      301 attgtcctgg aagacatctt tactttatgg agacaggtgg aaaccaaagt tcgagctaaa
      361 atccgtaaga tgaaggtgac aacaaaagtc aaccgtcatg acaaaatcaa tggaaagagg
      421 aagaccgcca aagaacatct gaggaaacta agcatgaaag aacgtgagca cggagaaaag
      481 gagaggcagg tgtcagaggc agaggaaaat gggaaattgg atatgaaaga aatacacacc
      541 tacatggaaa tgtttcaacg tgcgcaagcg ttgcggcggc gggcagagga ctactacaga
      601 tgcaaaatca ccccttctgc aagaaagcct ctttgcaacc gggtcagaat ggcggcagtg
      661 gagcatcgtc attcttcagg attgccctac tggccctacc tcacagctga aactttaaaa
      721 aacaggatgg gccaccagcc acctcctcca actcaacaac attctataat tgataactcc
      781 ctgagcctca agacaccttc cgagtgtctg ctcactcccc ttccaccctc agctctaccc
      841 tcagcggatg ataatctcaa gacacctgcg gagtgtctgc tctatcccct tccaccctca
      901 gcggatgata atctcaagac acctcccgag tgtctgctca ctccccttcc accctcagct
      961 ccaccctcag tggatgataa tctcaagaca cctcccgagt gtgtctgctc actccccttc
     1021 caccctcagc ggatgataat ctcaagaaac taaggaagaa taaataaata atataaaaat
     1081 aaaa
//
